LOCUS       NM_001109327            3390 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus coronin 1C (Coro1c), mRNA.
ACCESSION   NM_001109327 XM_001080440 XM_017598446 XM_577254
VERSION     NM_001109327.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Meng,Z., Chen,Y., Wu,W., Yan,B., Meng,Y., Liang,Y., Yao,X. and
            Luo,J.
  TITLE     Exploring the Immune Infiltration Landscape and M2
            Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy
  JOURNAL   Front Endocrinol (Lausanne) 13, 841813 (2022)
   PUBMED   35692390
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3390)
  AUTHORS   Hoyer,M.J., Chitwood,P.J., Ebmeier,C.C., Striepen,J.F., Qi,R.Z.,
            Old,W.M. and Voeltz,G.K.
  TITLE     A Novel Class of ER Membrane Proteins Regulates ER-Associated
            Endosome Fission
  JOURNAL   Cell 175 (1), 254-265 (2018)
   PUBMED   30220460
REFERENCE   3  (bases 1 to 3390)
  AUTHORS   Williamson,R.C., Cowell,C.A., Hammond,C.L., Bergen,D.J.,
            Roper,J.A., Feng,Y., Rendall,T.C., Race,P.R. and Bass,M.D.
  TITLE     Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1
            and controlling GEF exposure
  JOURNAL   J Cell Sci 127 (Pt 19), 4292-4307 (2014)
   PUBMED   25074804
REFERENCE   4  (bases 1 to 3390)
  AUTHORS   Williams,H.C., San Martin,A., Adamo,C.M., Seidel-Rogol,B.,
            Pounkova,L., Datla,S.R., Lassegue,B., Bear,J.E. and Griendling,K.
  TITLE     Role of coronin 1B in PDGF-induced migration of vascular smooth
            muscle cells
  JOURNAL   Circ Res 111 (1), 56-65 (2012)
   PUBMED   22619279
REFERENCE   5  (bases 1 to 3390)
  AUTHORS   Chan,K.T., Roadcap,D.W., Holoweckyj,N. and Bear,J.E.
  TITLE     Coronin 1C harbours a second actin-binding site that confers
            co-operative binding to F-actin
  JOURNAL   Biochem J 444 (1), 89-96 (2012)
   PUBMED   22364218
REFERENCE   6  (bases 1 to 3390)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   7  (bases 1 to 3390)
  AUTHORS   Samarin,S.N., Koch,S., Ivanov,A.I., Parkos,C.A. and Nusrat,A.
  TITLE     Coronin 1C negatively regulates cell-matrix adhesion and motility
            of intestinal epithelial cells
  JOURNAL   Biochem Biophys Res Commun 391 (1), 394-400 (2010)
   PUBMED   19913511
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On or before Nov 3, 2022 this sequence version replaced
            XM_017598446.2, NM_001109327.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.45885.1,
                                           SRR26643294.46956.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                JAXUCZ010000012.1  48373573-48373660
            89-288              JAXUCZ010000012.1  48401403-48401602
            289-411             JAXUCZ010000012.1  48422928-48423050
            412-541             JAXUCZ010000012.1  48435501-48435630
            542-723             JAXUCZ010000012.1  48437149-48437330
            724-843             JAXUCZ010000012.1  48438230-48438349
            844-948             JAXUCZ010000012.1  48439185-48439289
            949-1094            JAXUCZ010000012.1  48440298-48440443
            1095-1152           JAXUCZ010000012.1  48441865-48441922
            1153-1398           JAXUCZ010000012.1  48442592-48442837
            1399-3390           JAXUCZ010000012.1  48443727-48445718
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..3390
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /note="coronin 1C"
                     /db_xref="GeneID:501841"
                     /db_xref="RGD:1564490"
     exon            1..88
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            89..288
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1518
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /note="coronin, actin binding protein 1C"
                     /codon_start=1
                     /product="coronin-1C"
                     /protein_id="NP_001102797.1"
                     /db_xref="GeneID:501841"
                     /db_xref="RGD:1564490"
                     /translation="MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPR
                     FVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSED
                     CTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV
                     GTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRRQEIVAEKEKAHEG
                     ARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPD
                     TSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIAR
                     FFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKH
                     GYIPGKNRDLKVVKKNILDSKPAANKKSDLICAPKKTTDTASVQNEAKLDEILKEIKS
                     IKDTICNQDERISKLEQQLAKMAA"
     exon            289..411
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            412..541
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            542..723
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            724..843
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            844..948
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1094
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1152
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1398
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..3390
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgccaggc gggaggcggc agcggttgga aggcttcgcg gggctttgca gctgggactt
       61 cggcggcgcc tcaggcaccc gggctctgac acgatgcggc gagtggtacg acagagcaag
      121 ttccggcacg tctttggaca ggcagtgaag aatgaccagt gctacgatga catccgcgtc
      181 tcccgagtca cctgggacag ctccttttgt gctgtcaacc ccagattcgt ggccatcatc
      241 atagaagcga gtgggggagg ggccttcctg gtgctccctc tgcacaagac gggacgaatt
      301 gacaaatcct accctacagt gtgtggccac acaggaccag tgctggacat agactggtgc
      361 ccacacaacg accaggtcat cgccagcggc tcagaggact gcactgtgat ggtttggcag
      421 atcccggaaa atggactgac cctttccctg actgaacctg tggtgatttt agaaggtcac
      481 tcaaaaagag ttggcatcgt ggcctggcat ccgacggccc gcaatgtgct tctcagtgca
      541 ggctgtgata atgccattat catctggaac gtggggacag gggaggccct catcaacttg
      601 gacgacatgc attcagacat gatttacaac gtgagctgga gccgcaatgg cagtctcatc
      661 tgcacagcgt ccaaagacaa gaaagtgagg gtcatcgatc ccaggagaca ggagatcgta
      721 gcggaaaagg agaaagcaca cgaaggagcc aggcccatgc gcgccatctt cctggccgac
      781 ggcaatgtct tcactactgg ttttagccgt atgagcgagc ggcagttggc actctggaac
      841 ccaaaaaaca tgcaggaacc aattgctctt catgaaatgg acactagcaa tggggtgctg
      901 ctccctttct acgacccgga caccagcatc atttacttat gtgggaaggg tgacagcagt
      961 atccgctact ttgaaatcac ggatgagtcc ccatacgtgc actacctcaa caccttcagc
     1021 agcaaggagc ctcagcgagg gatgggctac atgcccaagc gggggcttga cgtcaacaag
     1081 tgtgagatcg ccagattctt caagcttcac gagagaaagt gtgaacctat tatcatgaca
     1141 gtccccagga agtctgacct cttccaagat gacctgtacc ctgacacagc ggggccggaa
     1201 gcagcacttg aggcagagga gtggtttgag gggaaaaacg cagaccccat cctcatctcc
     1261 ttgaagcatg ggtacattcc aggcaagaac agggatctca aggtcgtcaa gaagaacatt
     1321 ctggacagca agccagctgc aaacaagaag agtgatctca tctgtgcccc taagaagacc
     1381 acagacacag ccagtgtgca aaatgaagcc aagctggatg agattttaaa agagatcaaa
     1441 tccataaagg acacaatctg caatcaagac gagcgcattt caaagctaga acagcagctg
     1501 gccaagatgg ctgcctgagg tcgccacccc cacagccggc agggcagctg ctcactggct
     1561 tgctccaagg gagggcagaa gggagacact gccattggag acattccatt tcagatctgt
     1621 cagccagcga taggccacat tccagtaaga actccattcc tctctcaaat ttcccaaaac
     1681 atggaagcca agcttttcac gggggctgtt ggtgtttggc aggtctggtg acttgccgag
     1741 cttcaccgcg tcggaaatgc cgggtactct gaatcttaga aagcaaccct ccccacccag
     1801 cgtccccccc acccagcgtc ccccacctga ccagcccgag gccgcctctg cctgcctctt
     1861 cctttctaac gttgccaaac cagaagtcgc tcttctcctt tgtattttgc tactttgcag
     1921 tattcgtgtg tttttttttt cttctcctca attcaaaagg gacagcactg tgtacgttta
     1981 taactaaatg aagatgagat gattattttg tataaactca cgagaacaat cagcacagcc
     2041 acacagggct ggctcacagc acaaacctgg gcgtctaagc ctgtccagag gaagacttga
     2101 gaaatcacgt ggacccacac actgccctca tcccgctgag tctttgatca aaagttcatg
     2161 ccccctcccc tcccctccct ctctctctct ttctctctct ctctttacta caagttgggt
     2221 ggttgcacag acaggactca gctccttgat tgacgctgtg cctcggtgat tatactctaa
     2281 cccaaacgag cttgcgtctc tgcagttttg ttctccacag acggttgccc gtcccttcca
     2341 gcagtgtggg tcacttccgg gctgttttgg acaagggcac acaaggcgac cagatatccg
     2401 tgtgttgaga gtccttgtcc accaaggtag ctcacctggc ccttgggtct agtatggggc
     2461 ttgaacccag gcactttgtg cacagcctct gccccaggcg ccatttccct tgctctggtc
     2521 gtccctccct cctatgctgc ctcctgtctc aggcgcccag tcagtcctca agggctcttg
     2581 aatgttacag ccgagggaaa ggtccagaac aaagtagaga gggaagtcca gagagggccg
     2641 tggctggtca tgcacaggcc ctctgccacc cacccacatg aggtcagtgt cagagtggtc
     2701 ctgactgcag cacagcagtt ccctggccgt ggctggtcga gggcagctgg agcccagccc
     2761 taacttcagt ctcatgttgc atgtctgtga cagcaggcaa cctgggtagt gatcgtgaaa
     2821 ggcaagcctt ggcaggcgtt ggtgccagtg tgggcacagt gctggcacag cagtgcacag
     2881 gtcatcagga cagaggcaga gcagcagagc gtgcagcgca tgctcagagc ctgcactgac
     2941 tgagctctgt cggaagagaa gctctgagaa gacacctagg tgggttgcag gctccgaggg
     3001 tttctgtgtc catcttgtgt tttagtgttg ggtggtgaga cgtagagaag actgggaaca
     3061 ctggcgttgt ctgtatgcag ggagtgctga ggacctgtgt cacgattcac aaatgttctg
     3121 gggtcagttg aattaattag gtaaacaatt gtagaggctg gtgatgcagc cagaggcgat
     3181 gtggttcaga gaggaaggag tgactgtagt gtgtgccagg ctgagtaggc acctgacacg
     3241 ctgtggtggc ttctgttccc ctgttttgtc ttaaagccgt ggcaccggag gaggacagtg
     3301 tactgctcct acgcccactc ttatagagtg gccatagtgt tctgtcaaac actcgcttcc
     3361 gttttcagag ataaaagaca ttgattacaa
//
