LOCUS       NP_001102797             474 aa            linear   ROD 03-APR-2024
DEFINITION  coronin-1C [Rattus norvegicus].
ACCESSION   NP_001102797 XP_001080440 XP_017453935 XP_577254
VERSION     NP_001102797.1
DBSOURCE    REFSEQ: accession NM_001109327.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 474)
  AUTHORS   Meng,Z., Chen,Y., Wu,W., Yan,B., Meng,Y., Liang,Y., Yao,X. and
            Luo,J.
  TITLE     Exploring the Immune Infiltration Landscape and M2
            Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy
  JOURNAL   Front Endocrinol (Lausanne) 13, 841813 (2022)
   PUBMED   35692390
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 474)
  AUTHORS   Hoyer,M.J., Chitwood,P.J., Ebmeier,C.C., Striepen,J.F., Qi,R.Z.,
            Old,W.M. and Voeltz,G.K.
  TITLE     A Novel Class of ER Membrane Proteins Regulates ER-Associated
            Endosome Fission
  JOURNAL   Cell 175 (1), 254-265 (2018)
   PUBMED   30220460
REFERENCE   3  (residues 1 to 474)
  AUTHORS   Williamson,R.C., Cowell,C.A., Hammond,C.L., Bergen,D.J.,
            Roper,J.A., Feng,Y., Rendall,T.C., Race,P.R. and Bass,M.D.
  TITLE     Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1
            and controlling GEF exposure
  JOURNAL   J Cell Sci 127 (Pt 19), 4292-4307 (2014)
   PUBMED   25074804
REFERENCE   4  (residues 1 to 474)
  AUTHORS   Williams,H.C., San Martin,A., Adamo,C.M., Seidel-Rogol,B.,
            Pounkova,L., Datla,S.R., Lassegue,B., Bear,J.E. and Griendling,K.
  TITLE     Role of coronin 1B in PDGF-induced migration of vascular smooth
            muscle cells
  JOURNAL   Circ Res 111 (1), 56-65 (2012)
   PUBMED   22619279
REFERENCE   5  (residues 1 to 474)
  AUTHORS   Chan,K.T., Roadcap,D.W., Holoweckyj,N. and Bear,J.E.
  TITLE     Coronin 1C harbours a second actin-binding site that confers
            co-operative binding to F-actin
  JOURNAL   Biochem J 444 (1), 89-96 (2012)
   PUBMED   22364218
REFERENCE   6  (residues 1 to 474)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   7  (residues 1 to 474)
  AUTHORS   Samarin,S.N., Koch,S., Ivanov,A.I., Parkos,C.A. and Nusrat,A.
  TITLE     Coronin 1C negatively regulates cell-matrix adhesion and motility
            of intestinal epithelial cells
  JOURNAL   Biochem Biophys Res Commun 391 (1), 394-400 (2010)
   PUBMED   19913511
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On or before Nov 3, 2022 this sequence version replaced
            XP_017453935.1, XP_577254.2, XP_001080440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.45885.1,
                                           SRR26643294.46956.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     Protein         1..474
                     /product="coronin-1C"
                     /note="coronin, actin binding protein 1C"
                     /calculated_mol_wt=53047
     Region          8..>402
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Region          36..78
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          84..128
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          133..170
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          178..213
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          221..260
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          268..309
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..474
                     /gene="Coro1c"
                     /gene_synonym="RGD1564490"
                     /coded_by="NM_001109327.3:94..1518"
                     /db_xref="GeneID:501841"
                     /db_xref="RGD:1564490"
ORIGIN      
        1 mrrvvrqskf rhvfgqavkn dqcyddirvs rvtwdssfca vnprfvaiii easgggaflv
       61 lplhktgrid ksyptvcght gpvldidwcp hndqviasgs edctvmvwqi pengltlslt
      121 epvvileghs krvgivawhp tarnvllsag cdnaiiiwnv gtgealinld dmhsdmiynv
      181 swsrngslic taskdkkvrv idprrqeiva ekekahegar pmraifladg nvfttgfsrm
      241 serqlalwnp knmqepialh emdtsngvll pfydpdtsii ylcgkgdssi ryfeitdesp
      301 yvhylntfss kepqrgmgym pkrgldvnkc eiarffklhe rkcepiimtv prksdlfqdd
      361 lypdtagpea aleaeewfeg knadpilisl khgyipgknr dlkvvkknil dskpaankks
      421 dlicapkktt dtasvqneak ldeilkeiks ikdticnqde riskleqqla kmaa
//
