LOCUS       NM_001039022            1606 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus coenzyme Q5, methyltransferase (Coq5), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001039022 XM_222227
VERSION     NM_001039022.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1606)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1606)
  AUTHORS   Nguyen,T.P., Casarin,A., Desbats,M.A., Doimo,M., Trevisson,E.,
            Santos-Ocana,C., Navas,P., Clarke,C.F. and Salviati,L.
  TITLE     Molecular characterization of the human COQ5 C-methyltransferase in
            coenzyme Q10 biosynthesis
  JOURNAL   Biochim Biophys Acta 1841 (11), 1628-1638 (2014)
   PUBMED   25152161
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098719.1.
            
            On Jan 12, 2006 this sequence version replaced XM_222227.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098719.1, FQ219423.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132303, SAMD00155314
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1606
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..1606
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /note="coenzyme Q5, methyltransferase"
                     /db_xref="GeneID:304542"
                     /db_xref="RGD:1310857"
     exon            1..205
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..987
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /EC_number="2.1.1.201"
                     /note="ubiquinone biosynthesis methyltransferase COQ5,
                     mitochondrial; 2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase, mitochondrial; coenzyme Q5 homolog,
                     methyltransferase"
                     /codon_start=1
                     /product="2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase, mitochondrial precursor"
                     /protein_id="NP_001034111.1"
                     /db_xref="GeneID:304542"
                     /db_xref="RGD:1310857"
                     /translation="MAAPRSCVLWSYCGHGWSRLAGDCRLPGFRRSWLGATLSARSLS
                     QEKRAAETHFGFETVSEKEKGGKVYQVFQSVARKYDLMNDMMSLGIHRAWKDLLIRKM
                     HPLPGTQLLDVAGGTGDIAFRFLSYVQTQHERKQRRQLRTRQNLSWEEIARKYQSKED
                     PLGGSLVMVCDINREMLKVGKQKALARGHTAGLAWVLGDAEELPFDDDRFDVYTIAFG
                     IRNVTHIDRALQEAHRVLKPGGRFLCLEFSQVNDPLISRLYDLYSFQVIPVIGEVIAG
                     DWKSYQYLVESIRKFPNQEEFKDMIEDAGFQKVTYESLTSGIVAIHSGFKL"
     exon            206..355
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     exon            356..577
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     exon            578..684
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     exon            685..773
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     exon            774..885
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1559
                     /gene="Coq5"
                     /gene_synonym="RGD1310857"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagatggcgg cgcccaggag ctgtgttcta tggagctact gcggccacgg gtggtcgcga
       61 ttagcaggag actgcaggct ccccgggttt cgtagatctt ggctgggggc cacgctgagt
      121 gcgcggtcct tgtcccaaga gaagcgagcc gcggaaactc acttcgggtt tgagacggtg
      181 tcggaaaagg aaaaaggagg caaagtctac caggtgtttc agagcgtggc caggaagtac
      241 gacctgatga atgacatgat gagcctcggc atccaccgtg cctggaagga tttgctgatc
      301 aggaaaatgc acccgctgcc cgggacccag ctgctcgatg tggctggagg cacaggtgac
      361 attgcattcc ggttccttag ttacgttcag acacagcatg agaggaaaca gaggagacag
      421 ctgaggacgc ggcagaattt atcctgggaa gaaattgcca gaaagtacca gagtaaagag
      481 gaccccctgg gaggttcgct tgtcatggtc tgcgacatca acagggagat gctgaaggtc
      541 ggaaagcaga aagccttggc ccggggacac acggctggac ttgcgtgggt gctgggagac
      601 gctgaagaac tgccctttga tgatgacaga tttgacgttt acaccattgc ctttgggatc
      661 cggaatgtca cgcacattga ccgggctctc caggaagccc atcgagtcct aaagcctgga
      721 ggacggtttc tctgtctgga gtttagccaa gtgaatgacc ccctcatctc caggctttat
      781 gatctgtaca gcttccaggt catccctgtc atcggtgagg tcattgcagg agactggaag
      841 tcctatcaat accttgtgga aagtattcgc aagttcccaa atcaggaaga gttcaaggac
      901 atgatagaag acgcaggctt tcagaaggtg acttacgaga gcctgacttc agggattgtg
      961 gccattcact ctggcttcaa actctagctt ctttgctatt gtggagcaga agccaggcat
     1021 ttctactgaa gcccggggct ggaagatcat ctccctgatg agacagtagc tgagcatcca
     1081 ttcccctaag gctacaaagc cttcgattca tgttctgcat tgaccaggct caaaaaggaa
     1141 gaaaccaatt gctgcctttt ttgcagctct cattagtagc tgcccaggct gctgaggcct
     1201 tctcccacaa ttgtctggcc tagctgtgca ctgtgggagt cgggtaaaac cagcaggaat
     1261 gcagttttga agcttatgcg cagcttctct atgacagatg ttttctagag ggataatgga
     1321 tcactgggac cctaggagaa tttgaaccag cccttcagcc aaaagccaca gtccacttca
     1381 gaatgtcggt gccccagccc accggtgagg tgctcagtgg tgagcacctg tgagatctgg
     1441 ggctgtagac gcagcacagt ggagcgcatg cttggcctgt tgaggccctg ggcttggtgc
     1501 tcaccaggaa caagtaaaca gaagtagaac ctgtgaagca gtaaagttta caatttggga
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
