LOCUS       NM_001009671            1651 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Rattus norvegicus coenzyme Q10B (Coq10b), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001009671 XM_217393
VERSION     NM_001009671.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1651)
  AUTHORS   Kucharska,J., Gvozdjakova,A. and Simko,F.
  TITLE     Simvastatin decreased coenzyme Q in the left ventricle and skeletal
            muscle but not in the brain and liver in L-NAME-induced
            hypertension
  JOURNAL   Physiol Res 56 Suppl 2, S49-S54 (2007)
   PUBMED   17824807
  REMARK    GeneRIF: Administration of simvastatin under the condition of
            nitric oxide-deficiency reduced the level of coenzyme Q9/10 in the
            heart and skeletal muscle.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088273.1.
            
            On Jan 13, 2005 this sequence version replaced XM_217393.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088273.1, EX488032.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q31"
     gene            1..1651
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /note="coenzyme Q10B"
                     /db_xref="GeneID:301416"
                     /db_xref="RGD:1359509"
     exon            1..130
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..743
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /note="coenzyme Q10 homolog B"
                     /codon_start=1
                     /product="coenzyme Q-binding protein COQ10 homolog B,
                     mitochondrial"
                     /protein_id="NP_001009671.1"
                     /db_xref="GeneID:301416"
                     /db_xref="RGD:1359509"
                     /translation="MIMAARTSQRTLARVASGCRPKSTTVTEARVRGSARNVRYLAPC
                     GILMNRTLAPWASVLPKEICARTFFRITTPLVNKRKEYSERRIIGYSMQEMYDVVSGM
                     EDYKHFVPWCKKSDILSRRSGYCKTRLEIGFPPVLERYTSIVTLVKPHLVKASCTDGK
                     LFNHLETVWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFER
                     RACKLYGPETNIPRELMLHEIHHT"
     exon            131..280
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /inference="alignment:Splign:2.1.0"
     exon            281..473
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /inference="alignment:Splign:2.1.0"
     exon            474..575
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /inference="alignment:Splign:2.1.0"
     exon            576..1624
                     /gene="Coq10b"
                     /gene_synonym="RGD1359509"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcttcac aaagatgatc atggcagctc ggactagtca gaggactctg gctagggtgg
       61 catcgggatg ccgtccgaag tcaaccacag tgacggaagc ccgggtgcga gggtctgcgc
      121 gcaacgtcag gtacttagct ccctgtggta tactgatgaa cagaaccctt gcaccgtggg
      181 cctcagtttt gcctaaagag atctgtgcaa gaaccttctt cagaatcact acaccattag
      241 taaataagcg aaaggagtat tcagagagaa gaattatagg gtactccatg caggaaatgt
      301 atgatgtagt atcaggaatg gaagattata aacattttgt tccttggtgt aaaaagtcag
      361 atatattatc aaggagatct ggatattgta aaacccgatt agaaattggg tttccccctg
      421 ttttggagcg atacacatca atagtgacct tggtaaaacc acatttggta aaggcctctt
      481 gtactgatgg gaaacttttc aatcatctgg agactgtttg gcgattcagc ccaggtcttc
      541 ctggctatcc aagaacatgt accttggatt tttcaatttc ttttgaattc cgctcccttc
      601 tgcactctca gctcgctaca ctgttctttg atgaagttgt gaaacaaatg gtagcggcct
      661 ttgaaagaag agcttgtaaa ctgtatggtc cagagacaaa cattcctcgg gaattaatgc
      721 ttcatgaaat tcaccacacc tgagaggaaa acgagagctg cctccatcca tcttgactag
      781 tttgttcact tttaagaagc catttcacca gctattgaga agtcagacag catttgttaa
      841 acctgccttg actccaagcc cgctccattg aaaatttata cattgaatat ggactcactt
      901 gtacatagaa tcatttcttc aatcaagtgt aactctaagt aacgtgtaca tttgcaggct
      961 ctgcctgcct ttgtaataat ggatgtcatc actgttgcta ggataccaca ttcctcattt
     1021 gagtgcacag atgaacaagt cttttaattc tcaccttaca tgaaaggtta gccgagatac
     1081 aatgtctgtt atattaacca tatcatgtct aagttattag gttgaatatt tgtaacttat
     1141 tgttattagg catgtcatac agtttagggt attcgagtaa tcatatattt aacattaaaa
     1201 ctcagattta aagtactgcc aatgaggtct tagcactttg ggtattttaa attgttctta
     1261 tgggtcgcag gagatagttc agtgttgttg ggaagttgtt tgccagatgt actgagtggg
     1321 gtttttgttt tgtttgtttt tgctttttgt tttatttggt gagtggtcca gagctctgag
     1381 ctacttttct agacatttga aacttcctcc caggtgcttt gcactctttg ctgactgcat
     1441 tcaacctttt gtgtcactgt gggcgacata cgtagttccc atgtctgcag cacacgcagg
     1501 ccattcctat ttattgtgca tagtcacttt caataatagt ctgaactgat atttttttaa
     1561 aaaacaaatc agtgtaaggg ctgaagtcat gacttaataa agttaaattg tttatttttg
     1621 tataaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
