LOCUS       NM_001164091            1787 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus COP9 signalosome subunit 7A (Cops7a), transcript
            variant 1, mRNA.
ACCESSION   NM_001164091
VERSION     NM_001164091.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1787)
  AUTHORS   Sharon M, Mao H, Boeri Erba E, Stephens E, Zheng N and Robinson CV.
  TITLE     Symmetrical modularity of the COP9 signalosome complex suggests its
            multifunctionality
  JOURNAL   Structure 17 (1), 31-40 (2009)
   PUBMED   19141280
REFERENCE   2  (bases 1 to 1787)
  AUTHORS   Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ and Huang L.
  TITLE     Characterization of the human COP9 signalosome complex using
            affinity purification and mass spectrometry
  JOURNAL   J Proteome Res 7 (11), 4914-4925 (2008)
   PUBMED   18850735
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM122308.1, FM037577.1, AB259153.1, AI603423.1, DV719333.1 and
            CB326021.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript but encodes the shorter isoform (1).
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               FM122308.1         1-217
            218-218             FM037577.1         212-212
            219-601             FM122308.1         219-601
            602-838             AB259153.1         314-550
            839-1055            AI603423.1         1-217
            1056-1751           DV719333.1         34-729
            1752-1787           CB326021.1         1-36                c
FEATURES             Location/Qualifiers
     source          1..1787
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1787
                     /gene="Cops7a"
                     /note="COP9 signalosome subunit 7A"
                     /db_xref="GeneID:312710"
                     /db_xref="RGD:1310070"
     exon            1..122
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            123..327
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..993
                     /gene="Cops7a"
                     /note="isoform 1 is encoded by transcript variant 1; COP9
                     (constitutive photomorphogenic) homolog, subunit 7a; COP9
                     complex subunit 7a; COP9 constitutive photomorphogenic
                     homolog subunit 7A; COP9 signalosome complex subunit 7a"
                     /codon_start=1
                     /product="COP9 signalosome complex subunit 7a isoform 1"
                     /protein_id="NP_001157563.1"
                     /db_xref="GeneID:312710"
                     /db_xref="RGD:1310070"
                     /translation="MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFG
                     ELLDMPNVRELADSDFASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVV
                     TLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGR
                     DIQRQDLSAIAQTLQEWCVGCEVVLSGIEEQVSRANLHKEQQLGLKQQIESEVANLKK
                     TIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN"
     exon            328..403
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            404..492
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            493..695
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            696..801
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            802..953
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1771
                     /gene="Cops7a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttccaggt agcggtcggt cgcagtctgt cccagggtac gacccggcct tgggcacaga
       61 ttcgcggacc cggggctgcc tctttaaggg agggggtgga gccacgagtg aggatcgaaa
      121 agctccagaa aacttgaggc cagagccccg caccagggtg cagccatgag tgcggaggtg
      181 aaggtgacag ggcagaacca ggagcaattt ctgctccttg ccaagtcggc taagggggca
      241 gcactggcca cactcatcca ccaggtgctg gaggcccctg gtgtctacgt gtttggggaa
      301 ctgctggata tgcctaatgt tagagagctg gcagacagcg actttgcctc cacgttccgg
      361 ctgctcacag tgtttgccta tgggacctat gctgactact tagctgaagc caggaacctc
      421 cccccactta ctgaggctca gaagaacaag cttcgacatc tgtcagttgt cactctggct
      481 gccaaagtca agtgtatccc atatgcagtg ttgctggagg ctctcgccct tcgtaatgtg
      541 cgccagctgg aagacctcgt gatcgaggcc gtgtatgccg atgtccttcg tggatctctg
      601 gaccagcgca atcagcggct agaggttgac tacagcattg gacgggacat ccagcgccag
      661 gacctcagcg ccatcgccca aaccctgcaa gagtggtgcg taggctgtga ggttgtgctg
      721 tcaggcattg aagagcaagt cagccgtgcc aacctgcaca aggagcagca gctgggcctg
      781 aagcagcaga tcgagagtga ggttgccaac cttaagaaaa ccattaaagt tacaacagcg
      841 gccgctgctg cagccacttc ccaggaccct gagcaacacc tgacagagct gagagaacca
      901 gctcctggca ccaaccagcg ccaacccagc aagaaagcct caaagggcaa gggactccga
      961 gggagcgcca agatttggtc caagtcgaac tgaaaggact tgtttcttcc ctgggaatgt
     1021 ggggtcccag ctgcctacct gcctagccct taggattcct cagagagcct tcctgtgccc
     1081 ctggccagct gataatgcta gctcatgact tccatctcct ccacccccaa gcataaccac
     1141 atcctctgtg gggaggaggc cagtacaggt catgctatgt tggtacttct tacgtgtccc
     1201 attctcctcc ccaccacgct tgctcccatt gttctttagc actgtgtctg cccatgaccc
     1261 ccggcattga gcaggccggc agtcctacag agggtgctgg ctctccacta cccacaccta
     1321 cccctgcatg cctaacctgc agctcctcct cctgcctagt gggctgcatc tgaaaagcca
     1381 tggggaaggg ggtctccacc ttcatcccag ccttagagtt ctggagtcag tctgctaccc
     1441 tgggagtcac tggacatttt cctcccagaa ccccatcaca ctacattgtc tcttgtcctc
     1501 tctcatctcc ttgggcctgg ggatactgct gctccagtga ccccagagcc tgaggacaac
     1561 tatttctgag atgttaagaa atggttcttg gttagctaat catcttagga aacacaatgg
     1621 aaatcctgcc agaacttata tctcctgtgg ttttggtggg gaaggaaata tagattgtat
     1681 attaaaaata aaaagtatat atgaataggt ctatatataa catgacacag aaataaatct
     1741 atgagaaatc tatgtacaaa aatgccagga aaaaaaaaaa aaaaaaa
//
