LOCUS       NM_001004275            1598 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus COP9 signalosome subunit 4 (Cops4), mRNA.
ACCESSION   NM_001004275 XM_341189
VERSION     NM_001004275.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1598)
  AUTHORS   Granata,A., Koo,S.J., Haucke,V., Schiavo,G. and Warner,T.T.
  TITLE     CSN complex controls the stability of selected synaptic proteins
            via a torsinA-dependent process
  JOURNAL   EMBO J 30 (1), 181-193 (2011)
   PUBMED   21102408
REFERENCE   3  (bases 1 to 1598)
  AUTHORS   Sharon,M., Mao,H., Boeri Erba,E., Stephens,E., Zheng,N. and
            Robinson,C.V.
  TITLE     Symmetrical modularity of the COP9 signalosome complex suggests its
            multifunctionality
  JOURNAL   Structure 17 (1), 31-40 (2009)
   PUBMED   19141280
REFERENCE   4  (bases 1 to 1598)
  AUTHORS   Fang,L., Wang,X., Yamoah,K., Chen,P.L., Pan,Z.Q. and Huang,L.
  TITLE     Characterization of the human COP9 signalosome complex using
            affinity purification and mass spectrometry
  JOURNAL   J Proteome Res 7 (11), 4914-4925 (2008)
   PUBMED   18850735
REFERENCE   5  (bases 1 to 1598)
  AUTHORS   Wei,N., Tsuge,T., Serino,G., Dohmae,N., Takio,K., Matsui,M. and
            Deng,X.W.
  TITLE     The COP9 complex is conserved between plants and mammals and is
            related to the 26S proteasome regulatory complex
  JOURNAL   Curr Biol 8 (16), 919-922 (1998)
   PUBMED   9707402
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079384.1.
            
            On Sep 10, 2004 this sequence version replaced XM_341189.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079384.1, SRR8487226.215963.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1598
                     /gene="Cops4"
                     /note="COP9 signalosome subunit 4"
                     /db_xref="GeneID:360915"
                     /db_xref="RGD:1302952"
     exon            1..112
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1259
                     /gene="Cops4"
                     /note="SGN4; signalosome subunit 4; JAB1-containing
                     signalosome subunit 4; COP9 (constitutive
                     photomorphogenic) homolog, subunit 4"
                     /codon_start=1
                     /product="COP9 signalosome complex subunit 4"
                     /protein_id="NP_001004275.1"
                     /db_xref="GeneID:360915"
                     /db_xref="RGD:1302952"
                     /translation="MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGTEQLEA
                     LKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEVYHFTLEKVQPRVISFEEQ
                     VASIRQRLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDD
                     PVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVH
                     ESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGN
                     QLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPAAK
                     AEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTA
                     PEWTAQAMEAQMAQ"
     exon            113..192
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            193..344
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            345..448
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            449..602
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            603..753
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            754..924
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1040
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1125
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1573
                     /gene="Cops4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagaggtc ccgcagccgt ggctgagctg gaagaaagat ggcggctgcc gtgcgacagg
       61 atttggccca gctcatgaat tcaagcggct ctcacaaaga tctggcgggc aaatatcgtc
      121 agattctgga aaaagccatt cagttatctg ggacagaaca actagaagca ttgaaagctt
      181 ttgtggaagc gatggtgaac gagaacgtca gccttgtgat ctcacggcaa ctgctaacag
      241 atttctgcac acacctcccc aacctgccag acagcacagc caaggaggtc taccatttca
      301 ccttggagaa ggtccagcct cgggtcatct cctttgagga gcaggtggct tccatacgac
      361 agcgtcttgc atctatttat gagaaggaag aagactggag aaacgcagcc caagtgttgg
      421 tggggattcc tctggagaca ggacaaaaac agtacaacgt agactataag ctggagacct
      481 acctgaagat cgcgaggcta tacttggagg atgacgaccc tgtccaggct gaggcttaca
      541 taaaccgagc ttccttactt cagaatgaat ccacaaacga acagttacag atacactata
      601 aggtttgcta tgcacgtgtc cttgactaca gaaggaagtt cattgaagcc gcccaaaggt
      661 acaatgagct ctcttacaag acaatagtgc acgaaagtga gagactggag gccttgaagc
      721 acgcactgca ctgcaccatc ctagcgtcgg caggacagca gcgctctcgg atgctggcta
      781 ccctttttaa ggatgaaagg tgccagcaac tggctgctta tgggatcctg gagaaaatgt
      841 acctagacag gatcatcaga gggaaccagc ttcaagaatt tgctgcaatg ctgatgcctc
      901 accaaaaagc aaccacagct gatggttcca gcatcttgga cagagctgtt attgagcata
      961 atttgttgtc agcaagcaaa ttatataaca acatcacctt tgaggaactc ggagctcttt
     1021 tagagatccc tgcagctaag gcagaaaaga tagcatctca gatgataaca gaaggacgca
     1081 tgaacggatt tattgaccag atcgatggga tagttcattt tgaaacacga gaagccctgc
     1141 cgacgtggga caagcagatc caatcacttt gtttccaagt aaataacctc ctggagaaga
     1201 ttagtcagac agcccccgag tggacagcgc aagccatgga ggcgcagatg gcccagtgag
     1261 tcctggagct ccgtgcacac tgcgtctttg cactttgtgc ggatcgattc actgccctca
     1321 cagcatttgc atcgtgacca tagacatctc agtccttttt tgccagctcc cacgtgagga
     1381 cgacgcagga gcaagcagtg cagccttgaa gcagtagctc ccgtgccgcc tgggtctatg
     1441 ttgagctgac tcgggtgtct tgaaagcttg ttctttaagt gagcaagcga gcgagctggg
     1501 tagtcgtgta aaacttcagt gctttgtgcc tctccagatg tggttactct aataaacgga
     1561 gcgatgaacc agaaaaaaaa aaaaaaaaaa aaaaaaaa
//
