LOCUS       NM_001004200            1596 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus COP9 signalosome subunit 3 (Cops3), mRNA.
ACCESSION   NM_001004200 XM_213326
VERSION     NM_001004200.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Sharon,M., Mao,H., Boeri Erba,E., Stephens,E., Zheng,N. and
            Robinson,C.V.
  TITLE     Symmetrical modularity of the COP9 signalosome complex suggests its
            multifunctionality
  JOURNAL   Structure 17 (1), 31-40 (2009)
   PUBMED   19141280
REFERENCE   2  (bases 1 to 1596)
  AUTHORS   Fang,L., Wang,X., Yamoah,K., Chen,P.L., Pan,Z.Q. and Huang,L.
  TITLE     Characterization of the human COP9 signalosome complex using
            affinity purification and mass spectrometry
  JOURNAL   J Proteome Res 7 (11), 4914-4925 (2008)
   PUBMED   18850735
REFERENCE   3  (bases 1 to 1596)
  AUTHORS   Yan,J., Walz,K., Nakamura,H., Carattini-Rivera,S., Zhao,Q.,
            Vogel,H., Wei,N., Justice,M.J., Bradley,A. and Lupski,J.R.
  TITLE     COP9 signalosome subunit 3 is essential for maintenance of cell
            proliferation in the mouse embryonic epiblast
  JOURNAL   Mol Cell Biol 23 (19), 6798-6808 (2003)
   PUBMED   12972600
REFERENCE   4  (bases 1 to 1596)
  AUTHORS   Wei,N., Tsuge,T., Serino,G., Dohmae,N., Takio,K., Matsui,M. and
            Deng,X.W.
  TITLE     The COP9 complex is conserved between plants and mammals and is
            related to the 26S proteasome regulatory complex
  JOURNAL   Curr Biol 8 (16), 919-922 (1998)
   PUBMED   9707402
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079143.1.
            
            On Sep 10, 2004 this sequence version replaced XM_213326.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079143.1, FQ228882.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1596
                     /gene="Cops3"
                     /note="COP9 signalosome subunit 3"
                     /db_xref="GeneID:287367"
                     /db_xref="RGD:1303002"
     exon            1..99
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1316
                     /gene="Cops3"
                     /note="SGN3; signalosome subunit 3; COP9 (constitutive
                     photomorphogenic) homolog, subunit 3"
                     /codon_start=1
                     /product="COP9 signalosome complex subunit 3"
                     /protein_id="NP_001004200.1"
                     /db_xref="GeneID:287367"
                     /db_xref="RGD:1303002"
                     /translation="MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDT
                     VLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAG
                     LCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALP
                     YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSH
                     IMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELR
                     NLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEA
                     EKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKA
                     MDQEITVNPQFVQKSMGSQEDDSGNKPSSYS"
     exon            100..229
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            230..342
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            343..392
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            393..485
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            486..665
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            666..806
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            807..980
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1067
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1181
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1262
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1570
                     /gene="Cops3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgcgcgag ctacctctgt tgctttggcc accagcgggg aaacatggcg tctgctctgg
       61 agcagttcgt gaacagtgtc cgacagctct cagctcaagg gcagatgact cagctttgtg
      121 aactcatcaa caagagtgga gaactccttg cgaagaactt gtcccacttg gacactgtgc
      181 ttggggcttt agatgttcaa gaacactcat tgggtgtcct tgccgttctg tttgtgaagt
      241 tttccatgcc cagtgttcct gacttcgaga cactgttctc acaggtgcag cttttcatta
      301 gtacttgtaa cggcgagcac attcgatacg caacagatac gttcgctggg ctttgccatc
      361 agctaacaaa cgcactcgtg gagagaaaac agccccttcg aggaattggc atccttaagc
      421 aagccataga caagatgcag atgaatacaa accagctgac ctcagtacac gccgatctct
      481 gccagctctg tttactagcg aagtgcttta aacctgccct gccatatctt gatgtggata
      541 tgatggatat ctgtaaagag aatggagcct atgatgcaaa acactttctg tgctactact
      601 attatggagg gatgatctat acggggctga agaactttga aagagcactg tatttttatg
      661 agcaggccat aactacccca gccatggccg tcagccatat catgttggag tcatataaaa
      721 agtatatttt agtgtctttg atattacttg ggaaagtaca acagctgcct aaatacacct
      781 ctcaaattgt gggcagattt attaagcctc tcagcaacgc ttaccacgag ttagcacaag
      841 tttattcaac caacaacccg tccgagctcc ggaacctggt gaacaagcac agtgagacct
      901 tcactcgaga taacaacatg ggcctggtga agcagtgcct gtcgtctctt tataagaaga
      961 acattcagag gctgacaaag acctttttaa cactttcatt acaagatatg gcaagtcgcg
     1021 tgcagttatc tggacctcag gaggcagaaa agtatgttct acacatgata gaagatggag
     1081 aaatttttgc aagtattaac cagaaggatg gtatggtcag tttccatgat aatcctgaaa
     1141 agtataacaa cccagccatg cttcataaca ttgatcaaga gatgctaaaa tgcatagagc
     1201 tggatgagcg actgaaggcc atggaccagg agatcacagt gaacccccag tttgttcaaa
     1261 agagcatggg ctcacaagaa gatgactcag gaaacaagcc ctccagctac tcttgaaact
     1321 aactcccatc ctgaggtaac agccttgccc tggcaagtgt gaagagggag ggcagcagga
     1381 agtaccatgc tggtccacgc cggttcttcc tggacattca gaaattcagt tttaacatct
     1441 tcagttatat tgctttcaga aaaccattct ctgcaaagaa agaaaaaaaa atctacttta
     1501 gagtctgttg tggatttatt tatcctcaga ttattgttat tattgcatta aagttacctt
     1561 tttgttttaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
