LOCUS       NM_001134540            4374 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus COPI coat complex subunit alpha (Copa), mRNA.
ACCESSION   NM_001134540
VERSION     NM_001134540.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4374)
  AUTHORS   Kuliyev,E., Gingras,S., Guy,C.S., Howell,S., Vogel,P. and
            Pelletier,S.
  TITLE     Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron
            Viability
  JOURNAL   J Neurosci 38 (10), 2615-2630 (2018)
   PUBMED   29437892
REFERENCE   2  (bases 1 to 4374)
  AUTHORS   Peter,C.J., Evans,M., Thayanithy,V., Taniguchi-Ishigaki,N.,
            Bach,I., Kolpak,A., Bassell,G.J., Rossoll,W., Lorson,C.L., Bao,Z.Z.
            and Androphy,E.J.
  TITLE     The COPI vesicle complex binds and moves with survival motor neuron
            within axons
  JOURNAL   Hum Mol Genet 20 (9), 1701-1711 (2011)
   PUBMED   21300694
REFERENCE   3  (bases 1 to 4374)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 4374)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   5  (bases 1 to 4374)
  AUTHORS   Cao,Z., Li,C., Higginbotham,J.N., Franklin,J.L., Tabb,D.L.,
            Graves-Deal,R., Hill,S., Cheek,K., Jerome,W.G., Lapierre,L.A.,
            Goldenring,J.R., Ham,A.J. and Coffey,R.J.
  TITLE     Use of fluorescence-activated vesicle sorting for isolation of
            Naked2-associated, basolaterally targeted exocytic vesicles for
            proteomics analysis
  JOURNAL   Mol Cell Proteomics 7 (9), 1651-1667 (2008)
   PUBMED   18504258
REFERENCE   6  (bases 1 to 4374)
  AUTHORS   Wegmann,D., Hess,P., Baier,C., Wieland,F.T. and Reinhard,C.
  TITLE     Novel isotypic gamma/zeta subunits reveal three coatomer complexes
            in mammals
  JOURNAL   Mol Cell Biol 24 (3), 1070-1080 (2004)
   PUBMED   14729954
REFERENCE   7  (bases 1 to 4374)
  AUTHORS   Quek,H.H. and Chow,V.T.
  TITLE     Molecular and cellular studies of the human homolog of the 160-kD
            alpha-subunit of the coatomer protein complex
  JOURNAL   DNA Cell Biol 16 (3), 275-280 (1997)
   PUBMED   9115636
REFERENCE   8  (bases 1 to 4374)
  AUTHORS   Feurle,G.E., Hamscher,G., Kusiek,R., Meyer,H.E. and Metzger,J.W.
  TITLE     Identification of xenin, a xenopsin-related peptide, in the human
            gastric mucosa and its effect on exocrine pancreatic secretion
  JOURNAL   J Biol Chem 267 (31), 22305-22309 (1992)
   PUBMED   1429581
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473985.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169090.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4374
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..4374
                     /gene="Copa"
                     /note="COPI coat complex subunit alpha"
                     /db_xref="GeneID:304978"
                     /db_xref="RGD:1310525"
     exon            1..146
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..3781
                     /gene="Copa"
                     /note="coatomer protein complex subunit alpha"
                     /codon_start=1
                     /product="coatomer subunit alpha"
                     /protein_id="NP_001128012.1"
                     /db_xref="GeneID:304978"
                     /db_xref="RGD:1310525"
                     /translation="MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLI
                     DKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFH
                     HEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVR
                     VWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMP
                     LIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW
                     DMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLH
                     YVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYD
                     LYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKIQV
                     PNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAK
                     HAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDL
                     PIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQS
                     IIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVAL
                     LQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLG
                     DVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPP
                     APIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDED
                     GFVEAPEGLGEDTLGKGQEEGGGWDVEEDLELPPELDVPSGVAGGAEDGFFVPPTKGT
                     SPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVVQFGPYKQLFLQTYARGRTTYQA
                     LPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLSTVGKFEDAVEKFR
                     SILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMA
                     AYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILS
                     ACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVT
                     TVTEIGKDVIGLRISPLQFR"
     exon            147..260
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            261..334
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            335..415
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            416..492
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            493..602
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            603..712
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            713..812
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            813..948
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1031
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1182
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1249
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1325
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1408
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1548
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1634
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1773
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1936
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2083
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2084..2273
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2369
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2370..2458
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2582
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2583..2672
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2673..2782
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2783..2860
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2861..2929
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..3066
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            3067..3253
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            3254..3364
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            3365..3526
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            3527..3721
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
     exon            3722..4374
                     /gene="Copa"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcttccgg gagccgcgac ctggggtagc tgacgtggag cctttgggag tgcaaccggg
       61 agcggcggga tccgctaatc tgacctggga gccgaaggcc tgaaggatgc taaccaaatt
      121 cgagaccaaa agcgcgcggg tgaaaggcct tagttttcat cctaaaagac cctggatcct
      181 gaccagttta cataatgggg tcatccagtt atgggactat cggatgtgca ccctcattga
      241 caaatttgat gaacatgatg gtccagtgcg tggcattgac ttccataagc agcagcccct
      301 attcgtctct ggaggagatg actataagat taaggtttgg aattacaaac ttcggcgctg
      361 cctcttcaca ttgcttgggc acttggatta tatccgcacg acgttttttc atcatgagta
      421 tccttggatt ctgagcgcct cagatgatca gaccattcgg gtgtggaact ggcagtctag
      481 aacctgtgtc tgtgtgttaa cggggcacaa ccattatgta atgtgtgctc agttccaccc
      541 ctctgaagac ctggtggtat cagctagcct ggaccagact gtccgcgttt gggatatttc
      601 tggtctaagg aaaaaaaact tgtctcctgg tgcggtggag tccgatgtga gaggaataac
      661 tggggtcgat ctgtttggaa ctacagatgc agtggtgaag catgtgctag agggccatga
      721 ccgtggagtg aattgggctg ccttccaccc gactatgccc cttattgtat cgggggcaga
      781 tgaccggcaa gtgaagatat ggcgcatgaa tgaatcaaag gcatgggagg ttgacacctg
      841 ccggggccat tacaacaatg tgtcttgtgc cgtctttcac cctcgccaag agttgatcct
      901 cagcaattct gaggacaaga gtattcgagt ctgggatatg tctaagcgga ctggggttca
      961 gactttccgt agggatcatg atcgcttctg ggtcctggct gcccatccca accttaacct
     1021 ctttgcagca ggccatgatg gtgggatgat tgtatttaag ctggaacggg agcgtccagc
     1081 ctatgctgtt catggcaata tgctgcatta tgtgaaggac cgattcctcc gtcagctgga
     1141 tttcaacagc tccaaagatg tagctgtgat gcagttgcgg agtggttcta agttcccagt
     1201 gttcaacatg tcatacaatc cagcagagaa cgccgtgctg ctgtgcacca gagcaagcaa
     1261 tttagagaat agtacctatg atctgtacac catccccaaa gatgcagact cccagaatcc
     1321 tgatgcccct gaagggaaac gatcctcggg cctgacagcg gtttgggttg ctcggaatcg
     1381 gtttgctgtc ctagatcgaa tgcactcgct tctgattaaa aacctgaaaa atgagatcac
     1441 caagaaaatc caggtgccca actgtgatga aatcttctat gctggtacag gcaacctcct
     1501 gcttcgggat gcagattcca tcacactctt tgatgtccag cagaagcgaa ctctggcatc
     1561 agtgaagatt tccaaggtga aatatgttat ctggtcggca gacatgtctc atgttgcact
     1621 cctggccaag catgccattg tgatctgtaa ccgcaagctg gatgctctgt gtaacattca
     1681 tgagaacatt cgtgtcaaga gtggggcctg ggatgaaagt ggggtgttta tctataccac
     1741 aagcaaccac atcaaatatg ctgtcaccac tggggaccat gggatcatcc gaactctgga
     1801 tttgcccatc tatgtcacaa gagtgaaggg caataacgta tactgcctgg acagggagtg
     1861 tcgtcctcgg gtgctcacca ttgaccccac cgaattcaag ttcaaactgg ccctgatcaa
     1921 caggaagtat gatgaggtac tgcacatggt gaggaacgcc aaactagtag gccagtcgat
     1981 catcgcttac ctccagaaga agggttatcc tgaagtggca ctgcattttg taaaggatga
     2041 gaaaactcgt ttcagcttgg ccctggagtg tggaaacatt gagattgctc tagaggcagc
     2101 caaagctctg gatgacaaga actgctggga gaagctggga gaagtggccc tgttacaggg
     2161 caatcaccag attgtagaaa tgtgctatca gcgcaccaaa aactttgaca agctctcctt
     2221 cctgtacctt attactggca acctggagaa gcttcgaaag atgatgaaga ttgctgagat
     2281 ccgaaaggac atgagtggcc attatcagaa tgccctgtac ctgggtgatg tgtcagagag
     2341 agtgcgaatc ctgaagaact gtgggcagaa atccctggcc tacctcacag ctgctacaca
     2401 tggcttagat gaggaagctg agagcctgaa ggagacattt gaccctgaga aggagacaat
     2461 cccagatatt gatcctaatg ccaagctgct ccagccacca gcacctatca tgccattgga
     2521 taccaattgg cccttactga ctgtgtccaa agggttcttt gaaggctcca ttgcaagcaa
     2581 ggggaaggga ggcgcgttgg ctgccgacat tgacatcgac actgttggta ctgaaggctg
     2641 gggagaggac gcagagctgc agctggacga agatgggttt gtggaggctc cggaaggttt
     2701 gggggaggat actctcggca agggacaaga ggaaggaggt ggctgggacg tagaagaaga
     2761 tttggagctc ccacctgagc tggatgtacc ctctggggtt gccggtggtg ctgaagacgg
     2821 tttctttgtg cccccaacca agggaacaag cccaactcaa atctggtgca ataactccca
     2881 gcttccagtg gatcacatcc tggcaggttc ttttgaaaca gctatgcggc ttcttcatga
     2941 ccaggtggga gtagtccagt ttggccccta taagcaactg tttctacaga catacgcgcg
     3001 aggccgcacc acctaccaag cactgccctg cttgccctcc atgtatagct accctaatcg
     3061 caattggaag gacgcagggc tgaagaatgg tgtgccggct gtgggcctca agcttaacga
     3121 cctgatccag cggctgcagc tctgttacca gctcagcaca gtcggcaagt ttgaagacgc
     3181 tgtggagaaa ttccgctcca tcctactcag tgtgcccctt cttgtggtgg acaataaaca
     3241 ggagattgca gaggcccagc agctcatcac catctgccgt gagtacattg tgggtttgtg
     3301 catggagata gaaaggaaga agctacctaa ggagacccta gaccagcaga agcgcatctg
     3361 tgagatggcg gcttatttca cacactcaaa cctgcagcct gtgcacatga tcctggtgct
     3421 gaggacagcc ctcaacctct tcttcaagct caagaacttc aagacagctg ccacctttgc
     3481 ccgacgcctg ctggaacttg ggcccaaacc tgaagtagcc caacagacaa ggaaaatctt
     3541 gtctgcctgt gagaaaaacc ccacagatgc ctgccagctc aattatgaca tgcacaaccc
     3601 ctttgacatt tgtgctgcat cttaccggcc catctaccgt ggaaaaccag tggagaagtg
     3661 tccactcagt ggggcctgct attcccctga gttcaaaggg cagatctgca gggtcactac
     3721 agtgacagag attggcaaag atgtgattgg tctgaggatc agtcctcttc agtttcgcta
     3781 aggttctccc ttcacgtgca tggttaatca cacactgttc tttaaagtct ctagctgcaa
     3841 accctcactc tcccctacag ccacgattcg acttgttgag gttggttctc cctgaaaacg
     3901 tcatgttctt tctcttcgtt ggcaaatcag aagtttcaag cttgattttc ttgctcctgc
     3961 agacctctcc tgaagtttac tgtgcttgtg atcatagatg actttgcgtt tcagcttggg
     4021 ccttccaagg aacaaatgaa aactctgtgc tggccatttg tttagcaaat tctttagtat
     4081 ttattccttc cttaactacc gcctttggtc caattccact agcaagcagc aggatgcaag
     4141 aaatgacatt tttcctcagc caaacgaact gttaactatc ccatattttt cttgtgcatt
     4201 taatgtcata aataagttcc ttctttatgt gggcccacac acttgcaggc tgagaagaag
     4261 tcatttagtt ttgcaaaatc tgtaccagtt ttcactgatt tgttcctgtc ctttataact
     4321 taccattgtt cttatatcct gttgctcacc aaataaagta aatttctgag agtc
//
