LOCUS       NM_001033692            1183 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus COMM domain containing 9 (Commd9), mRNA.
ACCESSION   NM_001033692 XM_215781
VERSION     NM_001033692.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A,
            Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der
            Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B,
            Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH and van de
            Sluis B.
  TITLE     CCC- and WASH-mediated endosomal sorting of LDLR is required for
            normal clearance of circulating LDL
  JOURNAL   Nat Commun 7, 10961 (2016)
   PUBMED   26965651
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1183)
  AUTHORS   Liu YF, Swart M, Ke Y, Ly K and McDonald FJ.
  TITLE     Functional interaction of COMMD3 and COMMD9 with the epithelial
            sodium channel
  JOURNAL   Am J Physiol Renal Physiol 305 (1), F80-F89 (2013)
   PUBMED   23637203
  REMARK    GeneRIF: Suggest that COMMD3 and COMMD9 may be endogenous
            regulators of ENaC to regulate Na+ transport through altering ENaC
            cell surface expression.
REFERENCE   3  (bases 1 to 1183)
  AUTHORS   Dai C, Liang D, Li H, Sasaki M, Dawson TM and Dawson VL.
  TITLE     Functional identification of neuroprotective molecules
  JOURNAL   PLoS One 5 (11), e15008 (2010)
   PUBMED   21124846
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC101873.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by
            NM_001033692.2.
            
            On Sep 25, 2005 this sequence version replaced XM_215781.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101873.1, EU000469.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     gene            1..1183
                     /gene="Commd9"
                     /note="COMM domain containing 9"
                     /db_xref="GeneID:295956"
                     /db_xref="RGD:1307706"
     exon            1..57
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..603
                     /gene="Commd9"
                     /note="neuroprotective protein 9"
                     /codon_start=1
                     /product="COMM domain-containing protein 9"
                     /protein_id="NP_001028864.1"
                     /db_xref="GeneID:295956"
                     /db_xref="RGD:1307706"
                     /translation="MAALTSEHFVALQSLLKASSKDVVRQLCQESFSSSALHSKTLLD
                     NTCSSLSVTQEEAEQLLQALHHFTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKII
                     LEHISTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLC
                     GEKPSISAVTVELSKETLDTMLDGLGRIRDQLSAVANK"
     exon            58..183
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
     exon            184..323
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
     exon            324..358
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
     exon            359..462
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
     exon            463..1163
                     /gene="Commd9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgaaagatgg cggccttgac atcagagcat ttcgtggcgc tccagagcct gctgaaggcc
       61 tcctcaaaag atgtcgtcag acagctgtgc caagaaagct tctccagttc agcccttcac
      121 tcaaaaacac tcctggataa cacatgttcc agcttgtctg tgacccagga ggaggcagag
      181 caactgctcc aggctctgca ccacttcact aggctggtgg ccttccgtga cctgtcctct
      241 gctgaggcga ttctggctct ctttccggaa aatttccacc agaacctcaa aaacctgctg
      301 acaaaaatca tcctggagca catatcgact tggagaactg aagcccaagc aaaccagatc
      361 tctctgccac gcctagtgga cctggactgg agagtggata tcaaaacctc gtctgacagc
      421 atcagccgca tggccgtccc cacctgcctg ctccagatga agatccagga ggaccctagt
      481 ctgtgtggag agaaaccctc tatctcggct gtgaccgtgg agctgagcaa agaaacgctg
      541 gacaccatgt tagatgggct gggtcgcatt cgggaccagc tctctgctgt agctaataag
      601 taaggccagc agctattggc ctgggagggt gtggctgccg gcacagaggc tgacagtggc
      661 agacagtggg gtggaagggc tgctgctaca cagaaggcac agtggaggaa aggaagcggc
      721 catacccatg cccatgccca cggctcctct cttctcttcc tccttttgtt tttcctgaag
      781 atgagcaaag cctccatctc tgagaaggcc ctgtgtggag gtaaaccgcc ttcggccatg
      841 caaaggagca ggttcttcat cagccgcctg tgcactgcta taaagaactc aggccggtgc
      901 tgggcactca cctaatgatt tacctccagc tcacatgagc tcgtttccag cccagaatac
      961 atgagggaat tggggatgat gccagcagtg cctgcttccc catcacagac gtcagcagac
     1021 acataacgat cccctaagac ccctctctga gcttgcagcc ctgctgggcc acagctccaa
     1081 tgcagaaagc tggaacacac cactggccac tattcctgcg ctaggaagta agaagagttg
     1141 gaaataaata acagtgatga ttcaaaaaaa aaaaaaaaaa aaa
//
