LOCUS       NM_198732                957 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus COMM domain containing 3 (Commd3), mRNA.
ACCESSION   NM_198732 XM_214517
VERSION     NM_198732.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 957)
  AUTHORS   Liu,Y.F., Swart,M., Ke,Y., Ly,K. and McDonald,F.J.
  TITLE     Functional interaction of COMMD3 and COMMD9 with the epithelial
            sodium channel
  JOURNAL   Am J Physiol Renal Physiol 305 (1), F80-F89 (2013)
   PUBMED   23637203
  REMARK    GeneRIF: Suggest that COMMD3 and COMMD9 may be endogenous
            regulators of ENaC to regulate Na+ transport through altering ENaC
            cell surface expression.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On May 26, 2021 this sequence version replaced NM_198732.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060591.1, CF110580.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               JAXUCZ010000017.1  86235863-86236068
            207-318             JAXUCZ010000017.1  86237294-86237405
            319-382             JAXUCZ010000017.1  86237517-86237580
            383-417             JAXUCZ010000017.1  86237681-86237715
            418-478             JAXUCZ010000017.1  86238044-86238104
            479-535             JAXUCZ010000017.1  86238184-86238240
            536-595             JAXUCZ010000017.1  86238325-86238384
            596-957             JAXUCZ010000017.1  86239249-86239610
FEATURES             Location/Qualifiers
     source          1..957
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..957
                     /gene="Commd3"
                     /note="COMM domain containing 3"
                     /db_xref="GeneID:291339"
                     /db_xref="RGD:735116"
     exon            1..206
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..655
                     /gene="Commd3"
                     /codon_start=1
                     /product="COMM domain-containing protein 3"
                     /protein_id="NP_942027.1"
                     /db_xref="GeneID:291339"
                     /db_xref="RGD:735116"
                     /translation="MELSEYVQRGIQTLADPGSFDSSAFALLLRAAFQSLLDAQADEA
                     ALDHPDLKHIDPVVLKHCHGAAATYILEAGKHRVDKSTLSTYLEDCKFDRERIELFCT
                     EYQNNKNSLEILLGSIGRALPHITDVSWRLEYQIKTNQLHKMCRPGYLVTLNVENADS
                     QSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL"
     exon            207..318
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            319..382
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            383..417
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            418..478
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            479..535
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            536..595
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
     exon            596..957
                     /gene="Commd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccgatcag ctgggcgcgc gtcccgagtc acgtggtgcg catgtcgaag gtcacggcgc
       61 gctcacaatg gagctctccg agtatgtaca gagaggcatc cagacgctgg cggatcccgg
      121 ttcctttgac tccagcgcct tcgcgcttct cctccgggcg gctttccaga gcctgctgga
      181 cgcccaggcg gacgaggccg cgctagatca cccagacttg aaacatatcg acccagtggt
      241 tttaaagcat tgtcatgggg cagctgcaac ttacatactg gaggcaggaa agcaccgagt
      301 tgacaagtct actctaagca cttatttaga agactgtaaa tttgaccgag agcgaataga
      361 actgttttgc acggagtatc agaataataa gaattctcta gaaatcctac tgggaagtat
      421 aggtagagct ctccctcata taactgatgt ttcctggcga ttggaatatc agataaagac
      481 caaccaactt cataagatgt gtcgacctgg atatttagtg accttaaacg tagagaacgc
      541 tgattcccaa tcctacccag agattagttt tagctgcagc atggagcagt tacaggattt
      601 ggtggggaaa cttaaggatg cttcaaaaag cctggaaaga gcaactcagt tgtaacttgg
      661 ggaagctgat gacccaggag cctagaggaa aaccagacgc gccatgtctc ctgcaggacc
      721 ttcgatcgtg cgagctggat gtcattttca gtagaaaaag agctcccttt tgaagttatg
      781 ccagccatca gttttgacac tttttttaaa cacatgtgaa atggttaaga gggaaactct
      841 tacgcatttg aattttcaat attaatcttg cattccttct atgttgaacg ctttcaagcc
      901 ctatcaaagt atcgtaccct gaataaataa ggtggtattc ccacaataag ggcggta
//
