LOCUS       NM_001302967            5212 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus collagen type XVI alpha 1 chain (Col16a1), mRNA.
ACCESSION   NM_001302967
VERSION     NM_001302967.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   2  (bases 1 to 5212)
  AUTHORS   Bedal,K.B., Grassel,S., Oefner,P.J., Reinders,J., Reichert,T.E. and
            Bauer,R.
  TITLE     Collagen XVI induces expression of MMP9 via modulation of AP-1
            transcription factors and facilitates invasion of oral squamous
            cell carcinoma
  JOURNAL   PLoS One 9 (1), e86777 (2014)
   PUBMED   24466237
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5212)
  AUTHORS   Pogribny,I.P., Starlard-Davenport,A., Tryndyak,V.P., Han,T.,
            Ross,S.A., Rusyn,I. and Beland,F.A.
  TITLE     Difference in expression of hepatic microRNAs miR-29c, miR-34a,
            miR-155, and miR-200b is associated with strain-specific
            susceptibility to dietary nonalcoholic steatohepatitis in mice
  JOURNAL   Lab Invest 90 (10), 1437-1446 (2010)
   PUBMED   20548288
REFERENCE   4  (bases 1 to 5212)
  AUTHORS   Eble,J.A., Kassner,A., Niland,S., Morgelin,M., Grifka,J. and
            Grassel,S.
  TITLE     Collagen XVI harbors an integrin alpha1 beta1 recognition site in
            its C-terminal domains
  JOURNAL   J Biol Chem 281 (35), 25745-25756 (2006)
   PUBMED   16754661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760433,
                              SAMEA5760476 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-204               JAXUCZ010000005.1  147673096-147673299
            205-311             JAXUCZ010000005.1  147674838-147674944
            312-386             JAXUCZ010000005.1  147676911-147676985
            387-504             JAXUCZ010000005.1  147677069-147677186
            505-628             JAXUCZ010000005.1  147678058-147678181
            629-895             JAXUCZ010000005.1  147678450-147678716
            896-976             JAXUCZ010000005.1  147679645-147679725
            977-1102            JAXUCZ010000005.1  147679850-147679975
            1103-1156           JAXUCZ010000005.1  147680656-147680709
            1157-1183           JAXUCZ010000005.1  147681003-147681029
            1184-1219           JAXUCZ010000005.1  147681507-147681542
            1220-1246           JAXUCZ010000005.1  147682457-147682483
            1247-1309           JAXUCZ010000005.1  147683457-147683519
            1310-1351           JAXUCZ010000005.1  147683751-147683792
            1352-1396           JAXUCZ010000005.1  147683874-147683918
            1397-1432           JAXUCZ010000005.1  147683999-147684034
            1433-1495           JAXUCZ010000005.1  147684387-147684449
            1496-1540           JAXUCZ010000005.1  147684769-147684813
            1541-1636           JAXUCZ010000005.1  147684901-147684996
            1637-1675           JAXUCZ010000005.1  147685330-147685368
            1676-1720           JAXUCZ010000005.1  147685837-147685881
            1721-1756           JAXUCZ010000005.1  147686043-147686078
            1757-1867           JAXUCZ010000005.1  147686544-147686654
            1868-1903           JAXUCZ010000005.1  147687004-147687039
            1904-1939           JAXUCZ010000005.1  147687271-147687306
            1940-2050           JAXUCZ010000005.1  147687382-147687492
            2051-2095           JAXUCZ010000005.1  147687727-147687771
            2096-2131           JAXUCZ010000005.1  147691012-147691047
            2132-2176           JAXUCZ010000005.1  147691135-147691179
            2177-2308           JAXUCZ010000005.1  147691459-147691590
            2309-2344           JAXUCZ010000005.1  147692249-147692284
            2345-2452           JAXUCZ010000005.1  147692637-147692744
            2453-2575           JAXUCZ010000005.1  147693006-147693128
            2576-2629           JAXUCZ010000005.1  147693229-147693282
            2630-2671           JAXUCZ010000005.1  147693823-147693864
            2672-2707           JAXUCZ010000005.1  147694342-147694377
            2708-2761           JAXUCZ010000005.1  147694461-147694514
            2762-2830           JAXUCZ010000005.1  147694659-147694727
            2831-2857           JAXUCZ010000005.1  147698583-147698609
            2858-2917           JAXUCZ010000005.1  147699213-147699272
            2918-2965           JAXUCZ010000005.1  147699412-147699459
            2966-3019           JAXUCZ010000005.1  147699589-147699642
            3020-3073           JAXUCZ010000005.1  147703665-147703718
            3074-3106           JAXUCZ010000005.1  147703898-147703930
            3107-3223           JAXUCZ010000005.1  147705898-147706014
            3224-3265           JAXUCZ010000005.1  147706206-147706247
            3266-3352           JAXUCZ010000005.1  147706342-147706428
            3353-3397           JAXUCZ010000005.1  147707249-147707293
            3398-3451           JAXUCZ010000005.1  147709778-147709831
            3452-3505           JAXUCZ010000005.1  147710327-147710380
            3506-3559           JAXUCZ010000005.1  147710885-147710938
            3560-3604           JAXUCZ010000005.1  147712355-147712399
            3605-3658           JAXUCZ010000005.1  147712503-147712556
            3659-3694           JAXUCZ010000005.1  147712724-147712759
            3695-3757           JAXUCZ010000005.1  147713017-147713079
            3758-3829           JAXUCZ010000005.1  147715168-147715239
            3830-3883           JAXUCZ010000005.1  147715398-147715451
            3884-3928           JAXUCZ010000005.1  147716062-147716106
            3929-3973           JAXUCZ010000005.1  147716252-147716296
            3974-4027           JAXUCZ010000005.1  147716591-147716644
            4028-4081           JAXUCZ010000005.1  147717000-147717053
            4082-4132           JAXUCZ010000005.1  147718795-147718845
            4133-4222           JAXUCZ010000005.1  147719164-147719253
            4223-4258           JAXUCZ010000005.1  147721066-147721101
            4259-4303           JAXUCZ010000005.1  147722377-147722421
            4304-4492           JAXUCZ010000005.1  147723177-147723365
            4493-4559           JAXUCZ010000005.1  147723836-147723902
            4560-4736           JAXUCZ010000005.1  147724499-147724675
            4737-4814           JAXUCZ010000005.1  147725845-147725922
            4815-5212           JAXUCZ010000005.1  147726610-147727007
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5212
                     /gene="Col16a1"
                     /note="collagen type XVI alpha 1 chain"
                     /db_xref="GeneID:366474"
                     /db_xref="RGD:1310982"
     exon            1..204
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            205..311
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..5017
                     /gene="Col16a1"
                     /note="procollagen, type XVI, alpha 1; collagen
                     alpha-1(XVI) chain; collagen, type XVI, alpha 1"
                     /codon_start=1
                     /product="collagen alpha-1(XVI) chain precursor"
                     /protein_id="NP_001289896.1"
                     /db_xref="GeneID:366474"
                     /db_xref="RGD:1310982"
                     /translation="MLVSWAPGLWVLGLWATFSHGTNIGERCPTSQEEGLKLEHSSDP
                     STNMTGFNLIRRLNLMKTSAIKKIRNPKGPLILRLGAAPLTQATRRVFPRGLPEEFAL
                     VLTVLLKKHTFRNTWYLFQVTDANGYPQVSLEVNSQERTLELRAQGQDGDFVSCIFPV
                     PQLFDLRWHKLMLSVASRVASVHVDCVSASSQPLGPRQPIRPGGHVFLGLDAEQGKPV
                     SFDLQQAHIYCDPELVLEEGCCEILPGGCPPETSKSRRDTQSNELIEINPQTEGKVYT
                     RCFCLEEPHNSKVDAQLMGRSSQKAERGTKAHQETGASECPPCARSARESNVTLGPPG
                     LKGGKGDQGLTGPSGPKGEKGARGNDCVRISPDGPLQCAEGPKGEKGESGDLGPSGLP
                     GPTGQKGQKGEKGDGGLKGLPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPG
                     PPGLPGPPGIGLPGTPGDPGGPPGPKGAKGSSGIPGKEGPGGKPGKPGVPGTKGEKGD
                     PCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPAPAREGLGTVGLKGDRGDPGIQGMKGE
                     KGEPCSSCSSGVGAQHLGPSTGVNEDMGSPVHGLPGLPGKPGIPGPRGMKGEKGSFGD
                     AGPAGVAGPPGPVGPAGIKGAKGEPCEPCASLSKLQDGDTQVVHLPGPAGEKGEPGPP
                     GSGLPGKQGRAGERGLKGQKGDAGNPGDPGTPGITGQPGMSGEPGVRGPAGPKGEKGD
                     GCTACPSLQGALTDVSGLPGKPGPKGEPGPEGVGRPGKPGQPGLPGVQGPPGLKGTQG
                     EPGPPGTGAEGPQGEPGTPGLPGIQGPPGPRGPPGSTGEHGAQGPPGPKGATGPMGPP
                     GASISGPPGQKGSRGEKGEPGECSCPSRGEPIFSGMPGAPGLWMGSSSQPGPQGPPGV
                     PGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGSLPIEQHLLKSICGDCAQGQAAHSAS
                     LLVKGEKGDQGVPGVPGFNDCARCFIERERPRAEEARGDNSEGEPGCPGSPGLPGPPG
                     MPGQRGEEGPPGMRGSPGLPGPVGLQGERGPTGLTGDKGEPGPPGQPGYPGAMGPPGL
                     PGIKGERGYAGPAGEKGESGPPGSEGLPGPQGPAGPRGERGPQGSSGEKGDQGFQGQP
                     GFPGPPGPPGFPGKAGAPGPPGPQAEKGSEGMRGPSGLPGSPGPPGPPGIQGPAGLDG
                     LDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSSGRPGA
                     EGEPGAMGPQGRPGPPGHLGPQGPPGQPGPPGLSTMGLKGDRGSPGERGLAGLPGQPG
                     TPGHPGPPGEPGSDGAAGKEGPPGKQGLYGPPGPKGDPGPAGQKGQAGEKGRSGMPGG
                     PGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSMGDMVNYDDIKRFIRQEII
                     KLFDERMAYYTSRMQFPMEVAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQG
                     LPGMRGLPGTKGDKGDIGVGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPG
                     PPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPIKSMKGPFG"
     exon            312..386
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..504
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            505..628
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            629..895
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            896..976
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1102
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1156
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1183
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1219
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1246
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1309
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1351
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1396
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1432
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1495
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1540
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1636
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1675
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1720
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1756
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1867
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..1903
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..1939
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2050
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2095
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2131
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2176
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2308
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2344
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2452
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2575
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2629
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2671
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2672..2707
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2708..2761
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..2830
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2857
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2858..2917
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2918..2965
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2966..3019
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..3073
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3074..3106
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3223
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3224..3265
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3266..3352
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3353..3397
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3398..3451
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3505
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3506..3559
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3560..3604
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3605..3658
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3659..3694
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3695..3757
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3758..3829
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3830..3883
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3884..3928
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3929..3973
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4027
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4028..4081
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4132
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4133..4222
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4223..4258
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4259..4303
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4304..4492
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4493..4559
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4560..4736
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4814
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4815..5212
                     /gene="Col16a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgcccgg cagtcccggc aggcgtgcgc tgcggtgcgg cactcagtct agagaactcg
       61 ggacgcggaa aagctgggga caccgcagac tggcagggag agatcgagga ttcccctatg
      121 ggtctggacc cctggccctg cttcccatag ctggcggcct tggggctgcc aggattgctc
      181 agtgaaaggc tccccgggcc gttggtgctg aggctgtagc tgatctctct ggaccaacat
      241 gttggtatcc tgggctcccg gcctatgggt gcttgggctc tgggccacct tcagccatgg
      301 aacaaatata ggtgagcgct gcccaacttc acaggaagaa ggactcaagc tggaacacag
      361 cagtgacccg tcaaccaaca tgactggctt caacctaatc cgcaggctga accttatgaa
      421 gacatccgcc atcaaaaaga tccgcaaccc caaggggcct ctcatcttgc gactgggggc
      481 tgccccactg acccaagcaa ctcgacgagt gttccctcgg ggcctccccg aggagtttgc
      541 cctggtcctg acggtccttc tgaagaaaca caccttccgg aatacatggt acttattcca
      601 agtgactgac gcaaatgggt acccacaggt ctccttggaa gtcaacagcc aggagcggac
      661 tctagagctc cgggcacagg gccaagatgg tgactttgtg tcctgcatct tcccagtgcc
      721 tcagctcttc gatctgcgtt ggcacaagct gatgctgagc gtggcaagcc gtgtggcctc
      781 tgtgcatgtg gactgcgtct cggcttcctc ccagcctctg gggccccggc agcccatccg
      841 gcctggggga catgtgtttc tgggcttgga cgctgagcag ggcaagccgg tttcatttga
      901 ccttcagcag gcgcacatct actgtgaccc ggagctggtg ctggaggaag gctgctgtga
      961 gatcttaccg ggagggtgtc ccccagagac ctccaagtca cgccgggaca cccagagtaa
     1021 tgagctcatt gagatcaatc ctcagaccga gggcaaggtc tacacccgct gcttctgctt
     1081 ggaagaacct cataacagca aggtggacgc acagctgatg ggaagaagca gccagaaggc
     1141 agaaaggggg acaaaggccc accaggagac tggagccagc gagtgtccgc cctgtgcccg
     1201 cagcgcccgg gagagcaatg tcacacttgg tccccctggc ctcaagggag ggaaaggtga
     1261 ccaaggcctg actggaccat caggccccaa gggagagaag ggagcacggg gcaatgactg
     1321 tgttcgaatc tccccagatg gcccacttca gtgtgcagaa ggtccgaaag gagagaaggg
     1381 agaatcagga gacttgggac cctcaggact cccgggccca acaggccaga agggccagaa
     1441 aggggagaag ggcgatggag gcctcaaagg actgccggga aagccggggc gagatggtcg
     1501 gccaggagag atctgtgtca ttgggcccaa agggcagaaa ggagaccctg gctttgttgg
     1561 gcctgaggga ttggcaggag agcctgggcc ccctggccta cccggaccac ctgggatagg
     1621 actgcctggg actcctggag atccaggtgg cccaccaggc cctaaaggag caaagggcag
     1681 ctctggaata ccaggaaagg aaggcccagg agggaagccg gggaagccag gagtacccgg
     1741 gactaaggga gaaaagggtg acccctgtga agtgtgtcca acgctgcccg aagggttcca
     1801 gaactttgtg gggctccctg gaaagccagg gcctaaagga gaaccaggtg atcctgctcc
     1861 agccagggag ggcctaggaa ctgttggact gaaaggtgac cggggagatc caggcatcca
     1921 aggaatgaaa ggagagaagg gggaaccctg ctcatcctgc agttcaggtg ttggggccca
     1981 gcatcttggg ccctccactg gggtcaatga agacatgggc tcccctgtcc atggtttacc
     2041 tggccttccg ggcaaacctg gaattcccgg gccaagaggc atgaaaggag agaagggtag
     2101 ttttggcgat gctgggccgg ctggagttgc gggaccacca ggaccagtgg gaccggctgg
     2161 tatcaaaggg gcaaaggggg agccgtgtga gccctgtgca tctttgtcca agctccaaga
     2221 tggggacact caagtggttc acctgcccgg cccagctgga gagaagggag agcctgggcc
     2281 cccgggctcc gggctgcctg ggaagcaggg tagagctgga gagcgtggac tcaaggggca
     2341 gaagggggat gctgggaatc caggagaccc tggaacgcca ggcatcacag ggcagcctgg
     2401 aatgtctgga gagcctgggg ttcggggtcc tgcaggacca aaaggagaaa agggcgatgg
     2461 atgcactgcc tgccctagcc tgcagggggc gttgacagat gtatcgggac tgcctgggaa
     2521 accaggtccc aaaggagagc caggtcctga aggtgtgggt cggcccggta aaccaggcca
     2581 gcctggtcta ccaggagttc aagggcctcc aggactgaag ggcactcagg gagagcctgg
     2641 acctccaggc accggtgctg agggacccca gggggagcct ggaaccccag gtttgcctgg
     2701 cattcagggg ccccccggac ctcggggacc acctggctca accggcgaac acggtgccca
     2761 gggacctcca gggcccaaag gagccacagg acccatggga cctcctggtg ctagtatctc
     2821 tgggcctccg ggccaaaagg gatcacgagg agagaaaggt gaaccgggag agtgttcctg
     2881 tccttctcga ggagagccca tcttctccgg catgccgggt gctccgggac tgtggatggg
     2941 cagctcctcg cagccgggcc cgcagggtcc cccaggtgtc cccggaccac caggtccccc
     3001 cggaatgcct ggattgcagg gagtgcctgg acacaacggt ttgccaggac agcctgggct
     3061 cactgccgag ctgggatcct tacccatcga gcagcatctc ctcaagagca tctgtggtga
     3121 ctgtgcccag ggccaggcag cccattcagc ctcccttctg gtgaaaggag aaaaggggga
     3181 ccagggtgtc cctggtgtgc cgggtttcaa cgactgtgcc aggtgcttca tagagaggga
     3241 gcgcccgaga gctgaggagg ccaggggaga caacagtgag ggagaacctg gctgtcctgg
     3301 gagccctggc ctgcctggtc ctccagggat gcctggccaa agaggagaag agggtccacc
     3361 tggcatgagg ggctctcctg gtcttccagg ccctgttggt cttcaagggg agcgaggccc
     3421 cacaggcctg actggagaca agggagaacc gggtccccca ggacagcctg gctacccggg
     3481 tgccatgggt cccccaggac tgcctggcat caagggagaa agaggatatg ctggccctgc
     3541 gggagagaag ggggagtcgg gcccaccagg atctgaaggc cttccaggtc cccaaggtcc
     3601 agcgggtccc cgaggagagc gaggtcccca agggagctcg ggagagaagg gtgatcaggg
     3661 atttcaaggc cagccaggtt tccctggccc accgggtccc ccgggattcc caggcaaagc
     3721 tggagctcct ggcccacctg gcccccaagc agagaagggc agtgaaggga tgcgaggtcc
     3781 ctcaggcttg cctggttccc ctggaccacc aggccctcct gggattcagg gccctgctgg
     3841 actggatgga ctggatggga aagacggcaa accgggcctg aggggggacc caggtcccgc
     3901 tggccctcct ggactcatgg gacctccagg tttcaaaggg aaaacagggc atcctggtct
     3961 ccctggacct aagggtgact gtggaaaacc aggtcctcct ggcagcagtg gccggccagg
     4021 tgcagagggt gagcccggtg ccatgggacc ccagggacga ccaggacctc cagggcatct
     4081 tgggccacag gggcctccag gccagccagg tccacctggg ctctccacca tgggcctgaa
     4141 aggagatcgg ggatcccctg gagaaagggg cttggccggc ctcccaggcc agcctggcac
     4201 acccggacac cccggccctc cgggtgaacc tggttcggat ggtgcagctg gcaaagaggg
     4261 acctccagga aagcagggac tctatggacc ccccggccca aagggtgacc caggacctgc
     4321 aggacagaaa ggccaagcag gagaaaaggg aagatctggc atgcctgggg gccctggcaa
     4381 gagtggctcc atgggaccga ttggaccacc gggtcctgcg ggagagagag gccaccctgg
     4441 gtccccaggg cctgctggga accctggatt gcctggtttg ccaggctcta tgggagacat
     4501 ggtgaattat gatgatatca agaggtttat cagacaagag atcattaaac tgtttgatga
     4561 gaggatggct tactacacct ctaggatgca gttccccatg gaggtggcag cagctccagg
     4621 ccggccaggg cctccaggga aggatggcgc cccagggcgg ccaggtgctc cagggtcacc
     4681 tgggctccct ggtcagatag gccgagaagg acgccagggt ttgccaggaa tgagaggatt
     4741 gcctggtacc aaaggtgata agggagacat tggtgttggc attgcaggag aaaatggtct
     4801 ccctggccct ccaggtcctc aagggcctcc aggttatggc aagatgggtg caaccgggcc
     4861 aatgggccag caaggcattc ctgggatccc tggccccccg gggcccatgg gccagccagg
     4921 gaaggcaggc cactgcaacc cctcagactg ttttggggcc atgccaatgg agcagcagta
     4981 cccgcccata aaaagcatga aggggccttt tggttgaagc tcctgctcgc actgagagga
     5041 aggactctac taggaataaa tggccaaagc ttacaggact ctgacaggtt gtgaatgttt
     5101 gtactattct tgtgtttgtt gttttgttgt tgttgctgtt aatatttttt ttaacaataa
     5161 agaaagaaaa ctatctgtaa ccccacttcc atggggttcc cctggtgctg ca
//
