LOCUS       NM_001100535            5193 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus collagen type XV alpha 1 chain (Col15a1), mRNA.
ACCESSION   NM_001100535 XM_001066530 XM_003754014 XM_216399
VERSION     NM_001100535.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5193)
  AUTHORS   Barallobre-Barreiro,J., Gupta,S.K., Zoccarato,A.,
            Kitazume-Taneike,R., Fava,M., Yin,X., Werner,T., Hirt,M.N.,
            Zampetaki,A., Viviano,A., Chong,M., Bern,M., Kourliouros,A.,
            Domenech,N., Willeit,P., Shah,A.M., Jahangiri,M., Schaefer,L.,
            Fischer,J.W., Iozzo,R.V., Viner,R., Thum,T., Heineke,J.,
            Kichler,A., Otsu,K. and Mayr,M.
  TITLE     Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin
            Activity in Human Atrial Fibrillation
  JOURNAL   Circulation 134 (11), 817-832 (2016)
   PUBMED   27559042
REFERENCE   2  (bases 1 to 5193)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   3  (bases 1 to 5193)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   4  (bases 1 to 5193)
  AUTHORS   Didangelos,A., Yin,X., Mandal,K., Baumert,M., Jahangiri,M. and
            Mayr,M.
  TITLE     Proteomics characterization of extracellular space components in
            the human aorta
  JOURNAL   Mol Cell Proteomics 9 (9), 2048-2062 (2010)
   PUBMED   20551380
REFERENCE   5  (bases 1 to 5193)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 5193)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Feb 11, 2021 this sequence version replaced NM_001100535.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.18904.1,
                                           SRR26643295.21223.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               JAXUCZ010000005.1  66297546-66297843
            299-387             JAXUCZ010000005.1  66297927-66298015
            388-935             JAXUCZ010000005.1  66335977-66336524
            936-1010            JAXUCZ010000005.1  66338197-66338271
            1011-1091           JAXUCZ010000005.1  66339875-66339955
            1092-1236           JAXUCZ010000005.1  66344443-66344587
            1237-1346           JAXUCZ010000005.1  66347712-66347821
            1347-1481           JAXUCZ010000005.1  66349217-66349351
            1482-1607           JAXUCZ010000005.1  66350382-66350507
            1608-1811           JAXUCZ010000005.1  66352209-66352412
            1812-1940           JAXUCZ010000005.1  66352812-66352940
            1941-2033           JAXUCZ010000005.1  66358528-66358620
            2034-2159           JAXUCZ010000005.1  66359725-66359850
            2160-2222           JAXUCZ010000005.1  66360690-66360752
            2223-2258           JAXUCZ010000005.1  66368937-66368972
            2259-2399           JAXUCZ010000005.1  66369331-66369471
            2400-2465           JAXUCZ010000005.1  66369669-66369734
            2466-2501           JAXUCZ010000005.1  66371065-66371100
            2502-2585           JAXUCZ010000005.1  66371187-66371270
            2586-2651           JAXUCZ010000005.1  66372845-66372910
            2652-2687           JAXUCZ010000005.1  66374691-66374726
            2688-2750           JAXUCZ010000005.1  66377080-66377142
            2751-2819           JAXUCZ010000005.1  66378885-66378953
            2820-2855           JAXUCZ010000005.1  66379062-66379097
            2856-2909           JAXUCZ010000005.1  66381782-66381835
            2910-2969           JAXUCZ010000005.1  66381932-66381991
            2970-3038           JAXUCZ010000005.1  66382680-66382748
            3039-3080           JAXUCZ010000005.1  66382866-66382907
            3081-3126           JAXUCZ010000005.1  66385604-66385649
            3127-3207           JAXUCZ010000005.1  66388223-66388303
            3208-3257           JAXUCZ010000005.1  66388739-66388788
            3258-3350           JAXUCZ010000005.1  66389229-66389321
            3351-3495           JAXUCZ010000005.1  66389990-66390134
            3496-3560           JAXUCZ010000005.1  66393791-66393855
            3561-3689           JAXUCZ010000005.1  66396270-66396398
            3690-3749           JAXUCZ010000005.1  66396536-66396595
            3750-3809           JAXUCZ010000005.1  66397493-66397552
            3810-3995           JAXUCZ010000005.1  66400256-66400441
            3996-4111           JAXUCZ010000005.1  66400676-66400791
            4112-5193           JAXUCZ010000005.1  66402091-66403172
FEATURES             Location/Qualifiers
     source          1..5193
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..5193
                     /gene="Col15a1"
                     /note="collagen type XV alpha 1 chain"
                     /db_xref="GeneID:298069"
                     /db_xref="RGD:1310820"
     exon            1..298
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..4325
                     /gene="Col15a1"
                     /note="procollagen, type XV; collagen alpha-1(XV) chain;
                     collagen, type XV, alpha 1; collagen alpha-1(XV)
                     chain-like"
                     /codon_start=1
                     /product="collagen alpha-1(XV) chain precursor"
                     /protein_id="NP_001094005.1"
                     /db_xref="GeneID:298069"
                     /db_xref="RGD:1310820"
                     /translation="MTHRRTAQGRRPRWLLSIISTLLSTVLQTRAATGSASQDHLDLT
                     ELIGVPLPSSVSFVTGYGGFPAYSFRPGANVGRPARTLIPSTFFRDFAIGVAVKPSSA
                     QGGVLFAVTDAFQKVIYLGLRLSRVEDGRQRVILYYTEPGSHVSQEAAAFSVPVMTNR
                     WNRFAVTVQGEEAVLFMDCEEHSQVLFQRSSRPLTFEPSAGIFVGNAGATGLERFTGS
                     IQQLIIYSDPRTPEELCEAQESSASGEASGFQEMDEVAEIMEAVTYTQAPPKEAHVDP
                     ISMPPTSSSPTEDTELSGEPVPEGTPGTDLSITGHSSPEQGSGEILNDTLEVRTVDGN
                     PSTDGGSGDGALLNVTDGQGLSATATGETRVPVTTALEVENGSMPTGSPTLAMFTQSF
                     REVDMLDLENLTTASGDGEVPTSTDVDTEAGTLPTGGPTLKPREEATLGSLGEEWSTT
                     VVSKVPLNAFEEEEASGTAIDSLDAFTPTVVLEQASGTPTDIQAALTTTVAPEQVFTA
                     APTDGEDLVTSTEESDEEGSGSTLPIGPPLSKPTVTPERQVTLAGVEAEGSDPVWGVD
                     VGSGSGDIVGNEDLLRGPPGPPGPPGSPGIPGKPGTDVFVGPPGSPGEDGAPGEPGPQ
                     GPEGQPGLDGASGQPGMKGEKGARGPNGSVGEKGDPGSRGLPGPPGKNGEVGIPGAMG
                     PPGPPGPPGPPGPGCTTKLGFEIEGSGDTQLLSKPRISGPSSPSGPKGEKGEQGAKGE
                     RGTDGISTMGPPGPRGPPGRVEVLSSSLINITNGSMNFSDIPELMGPPGPDGVPGLPG
                     FPGPRGPKGDTGVPGFPGLKGEQGEKGEPGAILTGDIPLEMVKGRKGEPGVHGAPGPM
                     GPKGPPGHKGEFGLPGRPGRPGLNGLKGAKGDRGIMLPGPPGLPGPPGPPGPPGAVVN
                     IKGAVFPIPARPHCKTPVGTAHPGDPELVTFHGVKGEKGSWGLPGTKGEKGDQGAQGP
                     PGPPVDPAYLRHFLNSLKGENGDAAFRGESSHNLFVSGPPGLPGHPGLAGQKGEAVVG
                     PQGPPGIPGLPGPPGFGRPGVPGPPGPPGPPGPPAILGAAVPLPGPPGPPGQPGLPGS
                     RNLVTALSDMGDMLQKAHLVIEGTFIYLRESGEFFLRVRDGWKKLQLGELIPIPADSP
                     PPPALSSNPYQPQPPLNPILSANYERPVLHLVALNTPVAGDIRADFQCFQQARAAGLL
                     STFRAFLSSHLQDLSTVVRKAERFSLPIVNLKGQVLFNNWDSIFSGDGGQFNTHIPIY
                     SFDGRDVMTDPSWPQKVVWHGSNPHGVRLVDKYCEAWRTTDMAVTGFASPLSTGKILD
                     QKAYSCANRLIVLCIENSFMTDARK"
     exon            299..387
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            388..935
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1010
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1091
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1236
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1346
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1481
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1607
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..1811
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..1940
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1941..2033
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2034..2159
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2160..2222
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2223..2258
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2259..2399
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2400..2465
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2501
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2502..2585
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2586..2651
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2687
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2688..2750
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2819
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2855
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..2909
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2910..2969
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2970..3038
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3039..3080
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3081..3126
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3127..3207
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3208..3257
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3258..3350
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3351..3495
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3496..3560
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3561..3689
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3690..3749
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3750..3809
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3810..3995
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3996..4111
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4112..5193
                     /gene="Col15a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctatccca ggcggcccta aggttgtgga gctctgtgtc tgcatgcagg actttcctcg
       61 cgtgttacat aaggccctgg ggtggcgaga agaagggggc gtagggaggc gcggcgggaa
      121 ccagcggcga ggtggggcac cgcgcgtggg ggagcgcagg gcgcggcgga gtcgggtttc
      181 agagcgcggg tgactcaggc acgggcggca gccgggatcc cgccgccgcc gccgagcgcc
      241 gcctttgttc cgcgggcaaa gtggagctgg ggtccggcag ctgcaccatg acacacagga
      301 ggaccgcgca gggccggcgc ccgaggtggc tgctctccat catctccacg ctgctttcca
      361 ccgtcctgca gacgcgcgcc gcgacagggt cagcctctca ggaccacctg gacctcacag
      421 agctcattgg tgtcccatta ccctcatctg tgtcctttgt caccggctat ggtggtttcc
      481 cggcttacag cttccggcct ggggccaatg tcggccgccc agccaggacc ctcatcccat
      541 cgaccttctt cagggatttc gccatcggtg tggcagtgaa gcccagtagt gcccaagggg
      601 gcgtgctttt cgctgttact gatgctttcc agaaagtcat ctacctgggc ctgcggcttt
      661 cccgtgtaga ggacggccgc cagcgggtta tcctctacta cacggaaccc ggctcccacg
      721 tgtcccagga ggctgctgct ttctcggtgc ccgtaatgac taacaggtgg aatcgctttg
      781 ctgtgaccgt ccagggcgag gaagcggtcc ttttcatgga ctgtgaggaa cacagccaag
      841 tccttttcca gcgatcttcc cggccgttga cttttgagcc cagtgccggg atctttgtgg
      901 gcaatgcagg agccaccggc ctggagagat ttacgggctc catacaacag ctcatcatct
      961 attcagaccc caggacccct gaggagctgt gtgaagcaca agagtcctcg gcatctggag
     1021 aagccagtgg gtttcaggag atggatgaag ttgctgaaat catggaagcc gtcacttaca
     1081 cacaagcccc gcctaaagaa gcacacgttg atcccataag catgccccct acttcatcct
     1141 ctcctactga ggacacagag ctttctgggg aaccggttcc agaaggaacc ccaggaactg
     1201 acctgagcat cactggacac agcagccctg agcaagggtc tggtgaaatc ctgaatgata
     1261 ccctggaggt ccgtactgtg gatgggaacc ccagtactga tggtggttca ggggatgggg
     1321 ccttgctgaa cgtcactgac ggtcaggggt tatcagcaac agcaactggg gagaccaggg
     1381 tgcctgtcac cactgccctg gaagtagaga atggcagtat gcccactggg agccccaccc
     1441 tggccatgtt tacccagagc ttcagggaag tagacatgct ggatctagaa aatctaacaa
     1501 cagcatcagg ggatggtgag gtgcctacca gcactgatgt ggacacagag gctggcactt
     1561 tgcccactgg agggccaacc ctgaagccaa gagaagaggc cactctgggt tcactcggtg
     1621 aagaatggtc aaccacagtt gtgtccaaag tgcccctcaa tgcctttgag gaagaggaag
     1681 ccagcgggac tgccatcgac agcctggatg ccttcacacc cacagtggtc cttgagcaag
     1741 ccagcgggac ccctacagac attcaggctg ctctcaccac cacagtggcc cctgagcaag
     1801 tgtttactgc tgcacccaca gatggagaag acctggtgac ttctacagag gaatctgacg
     1861 aggagggatc tggtagcacc ctccccatag ggcccccgct ctccaaaccc acagtgactc
     1921 cagagaggca ggtcaccctg gcaggagtgg aggccgaggg gtcagaccct gtttggggcg
     1981 tggacgtggg ctcaggctct ggagacattg tgggcaatga agatctgttg agaggtcctc
     2041 caggtccccc aggcccaccg ggatcacctg ggattccagg gaaaccagga actgatgttt
     2101 tcgtgggacc tcctgggtct cctggagagg atggagctcc tggtgagcca ggaccccagg
     2161 gccctgaggg acagcctgga cttgatggag cctctggcca gcctggaatg aaaggagaga
     2221 agggagcaag aggacctaac ggctccgttg gcgagaaggg cgaccctggc agccgaggct
     2281 taccagggcc cccagggaag aacggagaag ttggtatccc tggggccatg ggaccgccgg
     2341 ggcctcctgg accccctggg cctccaggtc cgggatgtac aaccaagctt ggatttgaga
     2401 ttgaaggctc tggggacacc cagctgctga gcaaacccag aatctcggga ccctcctctc
     2461 caagtggtcc caaaggagaa aaaggagaac aaggagccaa gggtgaacgg gggacagacg
     2521 gaatcagcac tatggggcct cctgggccca gggggccacc tggacgtgtt gaggtcctgt
     2581 ccagttcttt gatcaacatc accaatggat ccatgaattt ctcagacatt cctgagctca
     2641 tggggcctcc ggggccagac ggtgtgccgg ggctgccagg gtttccaggc cccagaggac
     2701 caaaaggtga cactggtgtg cctggattcc caggtctaaa aggagaacag ggtgagaagg
     2761 gagagcctgg agccatcttg actggggata tccctctgga aatggtgaag gggagaaagg
     2821 gtgaacctgg agttcatgga gcaccaggac ctatgggacc caaaggacca ccgggacaca
     2881 aaggagaatt tggcctccca ggacgacctg gtcgcccagg attgaatggc ctcaagggtg
     2941 ccaaaggaga ccgcgggatc atgttgcctg gtccacctgg cctacctgga cccccagggc
     3001 ccccaggacc ccctggagct gtggttaaca tcaaaggtgc tgtttttcca atacctgccc
     3061 ggccgcactg caaaacacca gttggtaccg ctcaccctgg tgacccagag cttgtcactt
     3121 tccacggtgt taaaggagag aaagggtcct ggggtcttcc tggcacaaaa ggagaaaagg
     3181 gggaccaagg agctcaagga ccaccaggcc ctccagtgga ccccgcttac ctgagacatt
     3241 ttctcaacag cctgaagggg gagaatggag atgctgcatt cagaggagag tccagccaca
     3301 acctctttgt atcagggcct ccaggcctac caggacaccc aggcctggct gggcagaaag
     3361 gagaggctgt tgtggggcct caaggacccc caggaattcc aggcctgcct gggccacctg
     3421 gctttgggag acctggtgtt cctggaccac cgggaccccc tgggccacca ggacctccgg
     3481 ccattctggg tgcagctgtg ccccttcccg gcccacctgg ccctccagga cagccaggac
     3541 tccccggatc cagaaacttg gtcacagcgc tcagtgacat gggtgacatg ctacagaaag
     3601 ctcacttggt catagaaggg acgttcatct acctgaggga aagtggggag tttttccttc
     3661 gtgtccgaga tggttggaaa aagttgcagt tgggagaact gatccccatt cctgctgaca
     3721 gccccccacc accagcactt tccagcaatc cgtaccagcc acagcctcca ctgaacccca
     3781 ttttaagtgc caattacgag agacctgttc tgcacctggt tgctctcaac acgccggtgg
     3841 ctggggacat ccgagcagat ttccagtgtt tccagcaggc cagggctgca ggactactgt
     3901 ccaccttccg agcgtttctg tcatcacact tgcaggatct ctccacagtt gtgcggaagg
     3961 cagagagatt cagtcttcca attgtgaacc tcaagggcca agtgcttttt aacaactggg
     4021 actcaatatt ttctggtgat ggaggtcaat tcaatacaca cattccgata tactcctttg
     4081 atggtcggga cgtgatgact gatccttcct ggccgcagaa ggttgtttgg cacggctcca
     4141 acccccatgg tgtccgcctc gtggacaagt actgtgaagc ctggcgaacc acggacatgg
     4201 cagtaacagg atttgcctcc ccactgagca cagggaagat tctggaccag aaagcatata
     4261 gctgtgctaa taggctaatc gttctgtgca tcgaaaacag tttcatgaca gacgcaagga
     4321 agtgataacc tccccatggt tcttaaaaga gtattctaat atttcttatg tgaagagttg
     4381 acactgaagt ctaaaatgtt gtaaatatta cagtttgttt ttttttatat tacacatctg
     4441 tccaaagaga aaccaaagaa aacatacctc agtatagtca aaaggaaaga cggaagggac
     4501 tcagacccaa gtcaaatcca gtccacatat tggtgctaga ttctgtggga agacacacct
     4561 ccctcccctc gcagtgtgtg aacacatccc taacacagag tagggcagtc tgaaaacagg
     4621 ggctggcatg gttgccccgt gcgttcttca gaaagtcatt ccttccttcc aaccctggct
     4681 gttgagggta agatgtcctt tgtgtttgct aacagcatca ccttttagat atgtgagaca
     4741 tagctccctc cctaagaaat gtgtgaacca agcgcttggc gataccacgc acggttccat
     4801 acagccagag aaagagagct gctccaaaga tcctgctcat gtttcctccg atatcgggat
     4861 ttaatatggt cccctaaaat attattgcct tcatgctgta gggttctgcc tgtctaccca
     4921 gtcatagttg agtgtggcat ctattgatgt aagtctgact tgctgggaag ttaaaattct
     4981 aggaagaagc agcacagaat cttgaccttc ccccaacgct cccccttccc atcccctgcg
     5041 ccgatcttaa gatttccatt tgacaagtct tgaattatga ctgcagctga aacagattcg
     5101 ttgagatgaa ttttatgaaa agtctgtatc atcatgctat agactccgat atccttttcc
     5161 atgtaagaac ataaagacat cttttccggg tgc
//
