LOCUS       NM_013142              11622 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus collagen type XII alpha 1 chain (Col12a1), mRNA.
ACCESSION   NM_013142 XM_017596099
VERSION     NM_013142.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 11622)
  AUTHORS   Wang,F. and Zhang,M.
  TITLE     Circ_001209 aggravates diabetic retinal vascular dysfunction
            through regulating miR-15b-5p/COL12A1
  JOURNAL   J Transl Med 19 (1), 294 (2021)
   PUBMED   34233716
  REMARK    GeneRIF: Circ_001209 aggravates diabetic retinal vascular
            dysfunction through regulating miR-15b-5p/COL12A1.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11622)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   3  (bases 1 to 11622)
  AUTHORS   Chiasserini,D., van Weering,J.R., Piersma,S.R., Pham,T.V.,
            Malekzadeh,A., Teunissen,C.E., de Wit,H. and Jimenez,C.R.
  TITLE     Proteomic analysis of cerebrospinal fluid extracellular vesicles: a
            comprehensive dataset
  JOURNAL   J Proteomics 106, 191-204 (2014)
   PUBMED   24769233
REFERENCE   4  (bases 1 to 11622)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   5  (bases 1 to 11622)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   6  (bases 1 to 11622)
  AUTHORS   Brafman,D.A., Phung,C., Kumar,N. and Willert,K.
  TITLE     Regulation of endodermal differentiation of human embryonic stem
            cells through integrin-ECM interactions
  JOURNAL   Cell Death Differ 20 (3), 369-381 (2013)
   PUBMED   23154389
REFERENCE   7  (bases 1 to 11622)
  AUTHORS   Stamer,W.D., Hoffman,E.A., Luther,J.M., Hachey,D.L. and Schey,K.L.
  TITLE     Protein profile of exosomes from trabecular meshwork cells
  JOURNAL   J Proteomics 74 (6), 796-804 (2011)
   PUBMED   21362503
REFERENCE   8  (bases 1 to 11622)
  AUTHORS   Didangelos,A., Yin,X., Mandal,K., Baumert,M., Jahangiri,M. and
            Mayr,M.
  TITLE     Proteomics characterization of extracellular space components in
            the human aorta
  JOURNAL   Mol Cell Proteomics 9 (9), 2048-2062 (2010)
   PUBMED   20551380
REFERENCE   9  (bases 1 to 11622)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   10 (bases 1 to 11622)
  AUTHORS   Kania,A.M., Reichenberger,E., Baur,S.T., Karimbux,N.Y.,
            Taylor,R.W., Olsen,B.R. and Nishimura,I.
  TITLE     Structural variation of type XII collagen at its carboxyl-terminal
            NC1 domain generated by tissue-specific alternative splicing
  JOURNAL   J Biol Chem 274 (31), 22053-22059 (1999)
   PUBMED   10419532
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On May 15, 2023 this sequence version replaced XM_017596099.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               JAXUCZ010000008.1  89545493-89545711   c
            220-328             JAXUCZ010000008.1  89542457-89542565   c
            329-445             JAXUCZ010000008.1  89534874-89534990   c
            446-589             JAXUCZ010000008.1  89533343-89533486   c
            590-649             JAXUCZ010000008.1  89532699-89532758   c
            650-913             JAXUCZ010000008.1  89530770-89531033   c
            914-1078            JAXUCZ010000008.1  89530437-89530601   c
            1079-1252           JAXUCZ010000008.1  89529258-89529431   c
            1253-1543           JAXUCZ010000008.1  89527104-89527394   c
            1544-2146           JAXUCZ010000008.1  89526080-89526682   c
            2147-2419           JAXUCZ010000008.1  89523900-89524172   c
            2420-2692           JAXUCZ010000008.1  89520461-89520733   c
            2693-2965           JAXUCZ010000008.1  89519702-89519974   c
            2966-3238           JAXUCZ010000008.1  89510320-89510592   c
            3239-3505           JAXUCZ010000008.1  89507037-89507303   c
            3506-3698           JAXUCZ010000008.1  89506293-89506485   c
            3699-3820           JAXUCZ010000008.1  89505244-89505365   c
            3821-3970           JAXUCZ010000008.1  89503382-89503531   c
            3971-4090           JAXUCZ010000008.1  89503181-89503300   c
            4091-4255           JAXUCZ010000008.1  89502917-89503081   c
            4256-4402           JAXUCZ010000008.1  89502056-89502202   c
            4403-4542           JAXUCZ010000008.1  89499588-89499727   c
            4543-4672           JAXUCZ010000008.1  89498960-89499089   c
            4673-4815           JAXUCZ010000008.1  89498304-89498446   c
            4816-4945           JAXUCZ010000008.1  89497870-89497999   c
            4946-5082           JAXUCZ010000008.1  89489762-89489898   c
            5083-5212           JAXUCZ010000008.1  89488189-89488318   c
            5213-5352           JAXUCZ010000008.1  89484771-89484910   c
            5353-5485           JAXUCZ010000008.1  89484032-89484164   c
            5486-5512           JAXUCZ010000008.1  89483899-89483925   c
            5513-5655           JAXUCZ010000008.1  89482725-89482867   c
            5656-5785           JAXUCZ010000008.1  89480755-89480884   c
            5786-5922           JAXUCZ010000008.1  89479415-89479551   c
            5923-6052           JAXUCZ010000008.1  89478857-89478986   c
            6053-6195           JAXUCZ010000008.1  89477715-89477857   c
            6196-6325           JAXUCZ010000008.1  89476465-89476594   c
            6326-6468           JAXUCZ010000008.1  89475520-89475662   c
            6469-6598           JAXUCZ010000008.1  89473375-89473504   c
            6599-6718           JAXUCZ010000008.1  89471581-89471700   c
            6719-6865           JAXUCZ010000008.1  89469155-89469301   c
            6866-6982           JAXUCZ010000008.1  89467782-89467898   c
            6983-7129           JAXUCZ010000008.1  89467487-89467633   c
            7130-7204           JAXUCZ010000008.1  89466797-89466871   c
            7205-7344           JAXUCZ010000008.1  89464677-89464816   c
            7345-7468           JAXUCZ010000008.1  89463159-89463282   c
            7469-7612           JAXUCZ010000008.1  89462872-89463015   c
            7613-7777           JAXUCZ010000008.1  89461030-89461194   c
            7778-7816           JAXUCZ010000008.1  89460266-89460304   c
            7817-7955           JAXUCZ010000008.1  89460029-89460167   c
            7956-8098           JAXUCZ010000008.1  89457838-89457980   c
            8099-8208           JAXUCZ010000008.1  89456533-89456642   c
            8209-8358           JAXUCZ010000008.1  89450016-89450165   c
            8359-8436           JAXUCZ010000008.1  89448485-89448562   c
            8437-8523           JAXUCZ010000008.1  89446918-89447004   c
            8524-8577           JAXUCZ010000008.1  89445321-89445374   c
            8578-8673           JAXUCZ010000008.1  89444729-89444824   c
            8674-8727           JAXUCZ010000008.1  89443901-89443954   c
            8728-8781           JAXUCZ010000008.1  89443339-89443392   c
            8782-8835           JAXUCZ010000008.1  89439855-89439908   c
            8836-8907           JAXUCZ010000008.1  89438389-89438460   c
            8908-8943           JAXUCZ010000008.1  89435443-89435478   c
            8944-9010           JAXUCZ010000008.1  89435284-89435350   c
            9011-9199           JAXUCZ010000008.1  89434394-89434582   c
            9200-9268           JAXUCZ010000008.1  89433411-89433479   c
            9269-9439           JAXUCZ010000008.1  89431051-89431221   c
            9440-11622          JAXUCZ010000008.1  89427834-89430016   c
FEATURES             Location/Qualifiers
     source          1..11622
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..11622
                     /gene="Col12a1"
                     /note="collagen type XII alpha 1 chain"
                     /db_xref="GeneID:25683"
                     /db_xref="RGD:2374"
     exon            1..219
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            220..328
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..9450
                     /gene="Col12a1"
                     /note="collagen alpha-1(XII) chain; procollagen, type XII,
                     alpha 1; collagen, type XII, alpha 1"
                     /codon_start=1
                     /product="collagen alpha-1(XII) chain precursor"
                     /protein_id="NP_037274.1"
                     /db_xref="GeneID:25683"
                     /db_xref="RGD:2374"
                     /translation="MQTGLPRALAALGVALLLSSIEAEVDPPSDLNFKIIDENTVHMS
                     WERPADPIVGYRITVDSTTDGPTKEFTLAASTTETLLSNLIPETQYVVTITSYDEVEE
                     SVPVIGQLTIETGDPAKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYIL
                     DFIVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYRREDLLAAIKKIPYKGGNTM
                     TGDAIDYLVKNTFTESAGSRAGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGI
                     KAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVI
                     EPPSNLVVTDLSSKFIRLRWDPSPSAVTGYKILLTPMAAGSRHHALSVGPQTTTLNVR
                     DLSADTEYQISVFAMKGLTSSEPVSVMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS
                     IGIANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDIIKAIN
                     NFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKLRN
                     SDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQEL
                     AAIKKKAYVPPKDLRFTQVTANSFKAEWSPAGDNVFSYHITYKDTTGDDEVTVVEPAS
                     STSVVLSNLKPETLYLVNVTAEYEDGFSVPVVGEETTAEVKGAPRNLKVTDETTDSFK
                     ITWSQAPGRVLRYRIMYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEISVIAEYSS
                     GPGSPLTGSAATEEVRGNPRDLRVSDATTSTLKLTWSGAPGKVKQYLVTYTPAAGGET
                     QEVTVRGDTTTTVLRNLKEGTQYDLSVTALYASGAGEALSGKGTTLEERGSPQNLVTK
                     DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKTLPGDAIHTMIENLQPETKYK
                     ISVFATYSSGEGEPVTGDATTELSQDSKILKVDEETEHTMRVTWKAAPGKVINYRVVY
                     RPQGGGRQMVAKVPPTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFK
                     SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEE
                     LRAGTTYRVNVFGMFDGGESLPLVGQEMTTLSDTTVTPFLSSGMECLTRAEADIVLLV
                     DGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWHLNAHRDKKSL
                     LQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPS
                     KKLKDEGVELFAIGIKNADEVELKMIATDPDDIHAYNVADFESLSKIVDDLTINLCNS
                     VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLE
                     TSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDIGPTTMHVQW
                     QPVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQAVLHDL
                     TSEPAKAREATLPLPRPQDVKIRDVTHSTMNVIWEPVLGKVRKYTVRYKTPEEEFKEV
                     EVDRSRTSTTLKDLSSQTQYTVSVSAVYDEGTSPPATAHETTRPVPAPTNLQFTEVTP
                     ESFRGTWDHGASDVSLYRITWAPVGNPDKLETILNGDENTLLFENLDPNTLYDVSITA
                     IYPDESESEDLSGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQK
                     YRITYQPSTGEGNEQTTTVGGRQNSVVLQKLKPDSPYTITVSSQYPDGEGGRMTGRGK
                     TKPLNTVRNLRVYDPSTSTLSVRWDHAEGNPRQYKLFYAPAGGPEELVPIPGNTNYAI
                     LRNLQPDTPYTVTVVPVYAEGDGGRTSDTGRTLVRGLARNVQVYNPTPNSLDVRWDSA
                     PGPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNP
                     SPGQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPIVGDPIDEYTTV
                     PGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNMHISDEWYTR
                     FRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVYAQYD
                     SGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVKWSPHRAATSYRLKLSPADGTRGQE
                     ITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQTTVKPTEAPTEPPTPS
                     PPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQV
                     SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGM
                     RKNVPKVLVVVTDGRSQDEVKKAAFIIQQSGFSVFVVGVADVDYNELANIASKPSERH
                     VFIVDDFESFEKIEDNLITFVCETATSSCPLVYLDGYTSPGFKMLEAYNLTEKNFASV
                     QGVSLESGSFPSYSAYRLQKNAFINQPTAELHPNGLPPSYTIILLFRLLPETPSDPFA
                     IWQITDRDYRPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDADEAKTLFYGSFHKVHI
                     VVTSKSVKIYIDCYEIVEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQSFDIICS
                     PVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGI
                     NGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPG
                     LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGTPGSPGVTGPSGKPGKPGDHGRPGQ
                     SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSNRNQPGP
                     PGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPQGERGLPGEKGERGIGSQGPRGPPG
                     PPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGY
                     PGSG"
     exon            329..445
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            446..589
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..649
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            650..913
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1078
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1252
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1543
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..2146
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2419
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2420..2692
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2965
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2966..3238
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3239..3505
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3506..3698
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3699..3820
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3821..3970
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4090
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4091..4255
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4402
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4403..4542
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4543..4672
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4673..4815
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4816..4945
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            4946..5082
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5083..5212
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5213..5352
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5353..5485
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5486..5512
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5513..5655
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5656..5785
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5786..5922
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5923..6052
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6053..6195
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6196..6325
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6326..6468
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6469..6598
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6599..6718
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6719..6865
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6866..6982
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            6983..7129
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7130..7204
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7205..7344
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7345..7468
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7469..7612
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7613..7777
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7778..7816
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7817..7955
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            7956..8098
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8099..8208
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8209..8358
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8359..8436
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8437..8523
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8524..8577
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8578..8673
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8674..8727
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8728..8781
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8782..8835
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8836..8907
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8908..8943
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            8944..9010
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            9011..9199
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            9200..9268
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            9269..9439
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
     exon            9440..11622
                     /gene="Col12a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagtcagc aaaggcggcg ctgcagacgc gtccgcgggg cagctgcatt cagtccccct
       61 gcctccgctc cgcgccttgg gcgctgctcc tgggtgctcc cgccgccttt tccacacccg
      121 cggccgtcag gtgctcctgg agcgcagcgc cctcacaggc ccggggggtc ccacgcggag
      181 actgctggac gcccgctccc tctgtcacct ccggctcaga tcccttcatg aggctgtgag
      241 ctttgaggca caagcatgca gaccgggctt ccccgagcgc tggccgccct gggcgtggcc
      301 ctactcctgt cttctattga ggcagaagtt gacccacctt ccgacttgaa ttttaaaatt
      361 atagatgaaa atactgtcca tatgtcatgg gagagaccag ctgatccaat tgtgggttac
      421 agaataacag tggactctac aacagatggg cctactaaag aatttaccct tgcagctagt
      481 accactgaaa ccctattatc aaaccttatt cctgaaacac agtacgtggt caccatcact
      541 tcctacgatg aagtagaaga aagtgtgccg gttataggcc aactaacaat tgaaacaggt
      601 gatccagcaa aaccagggga gaagaaacct ggaaaaacag agatacaaaa gtgctctgtc
      661 agcgcctgga ccgacttagt gtttcttgtg gatggctcct ggagtgtggg aagaaataat
      721 ttcaagtaca ttttagactt cattgttgct cttgtgtctg cctttgacat tggggaggag
      781 aagacaaggg tgggagttgt tcagtacagc tcagacacca ggactgaatt taacttaaat
      841 cagtattacc gaagagaaga cctgcttgct gcaattaaaa aaataccata caaaggtggc
      901 aacacaatga caggggatgc cattgactac ttagtcaaaa acactttcac tgagtctgct
      961 ggctcaagag ctggctttcc taaagtggcg atcattatca cggatggcaa gtctcaggat
     1021 gaagtagaaa ttccagcacg ggaacttcgg aatattggag ttgaggtttt ctctctgggc
     1081 attaaagctg cagatgcaaa agaactcaaa caaattgcat ccacaccttc cctgaaccac
     1141 gtgttcaatg tggccaattt tgatgcaatc gtggacattc agaatgagat aatctcccag
     1201 gtgtgttcag gagttgatga gcaacttggt gagctggtca gtggagaaga agtcatcgag
     1261 cctccttcaa atctggtagt cacagatctc tcatcaaaat tcattaggct gagatgggat
     1321 ccgtctccca gcgctgtgac tggctataag atcctcctca caccaatggc tgccgggagc
     1381 cgccatcacg ctttgagtgt ggggccccag acgaccacgc tcaatgttcg tgacctttca
     1441 gctgacacag aataccagat cagcgttttt gccatgaagg ggctaacatc cagtgagcct
     1501 gtttcagtca tggagaagac acagccaatg aaagttcaag tagaatgttc acgtggtgtg
     1561 gatataaaag ccgacatcgt gtttttggtt gatggttcct acagcatcgg cattgcaaac
     1621 tttgttaaag ttagagcctt tttggaagtt cttgcaaaaa gttttgagat ttctccaaac
     1681 agggtgcaga taagccttgt ccagtacagc agagaccctc acactgaatt tacattgaag
     1741 gagtttaaca gagttgaaga cataatcaaa gcaataaata acttcccgta caggggagga
     1801 tccacaaaca caggcaaagc aatgacttac gtcagagaga aaatatttgt gcctaacaaa
     1861 ggctccagaa gcaacgtacc aaaggtgatg attctcatca cagatgggaa gtcgtcagat
     1921 gctttcaggg accctgctat aaaactcagg aactcggacg tggagatctt cgcagttggt
     1981 gtaaaggatg ctgtgcgctc agaactggaa gccattgcct ctcctcccgc tgagacacat
     2041 gtgttcacag tggaggactt cgatgccttt cagaggatat cgtttgaact cacacagtct
     2101 atctgtctta gaattgagca agagttggca gctataaaga agaaagctta tgtgccgcca
     2161 aaggatctga gatttactca ggtaactgct aatagtttca aagctgaatg gtctcctgct
     2221 ggagacaacg tcttctcgta tcacatcacg tacaaggaca ctactggtga cgatgaggtc
     2281 acagtggtgg agccagcctc cagcaccagt gttgttctca gcaacctgaa accagagacc
     2341 ctgtacttgg tgaatgtgac ggcagagtat gaggatggct tcagcgtccc tgtagttggg
     2401 gaggagacca cggctgaagt aaaaggagca ccacgaaacc tgaaggtgac tgatgagacg
     2461 acggacagtt ttaaaattac ctggtctcaa gctccaggga gagtcttaag gtaccgaatt
     2521 atgtacagac cagtttctgg tggagaaagt aaagaagtca gtactccagc caaccagagg
     2581 aggaaaacac tggagaacct gacgccagac acaaagtatg aaatatctgt aattgctgaa
     2641 tattcatccg gacctggctc tccactgaca ggaagtgcag ccactgaaga agttagaggg
     2701 aatccaagag acttaagagt ttctgatgcc acgacatcaa cgctgaagtt gacttggagt
     2761 ggggccccag gaaaagtgaa gcagtatctt gtcacataca ccccagcagc aggaggtgaa
     2821 actcaggagg tcactgtgag aggggataca accaccacgg tgttgaggaa cttgaaggaa
     2881 gggacacagt acgacttatc tgtgacagca ctgtatgcgt ctggggctgg tgaggccctt
     2941 tctggaaaag ggacaacact tgaagaacgt ggttcacctc aaaatctagt taccaaagac
     3001 atcacagaca catcaatcgg ggcctattgg acatctgctc cagggatggt tcgagggtac
     3061 agggtctcat ggaagtcgct ttatgacgat attgaggccg gagagaaaac tcttcctgga
     3121 gatgcaattc acactatgat tgagaatctg cagccagaga ccaagtacaa aatttcagtt
     3181 tttgcaactt acagcagtgg agaaggagag ccggtgactg gagatgccac aactgaatta
     3241 tctcaagact ccaaaatctt aaaagtggat gaagaaacag aacacacaat gagagttacc
     3301 tggaaagcag cgccggggaa agtcatcaac taccgcgttg tgtatcgccc tcaagggggt
     3361 gggagacaga tggttgctaa ggttccaccc acggtcactt caacagtgct aaagaggctt
     3421 caaccccaga ccacatatga catcacagtt ctcccaatgt ataagacagg agaaggaaag
     3481 cttagacaag gatcaggaac aacagcttct cgatttaaat cgccgagaaa cctcaaaact
     3541 tctgacccaa caatgtcaag tttccgagtg acttgggagc ctgcccctgg ggaagtgaaa
     3601 ggttacaaag tcacctttca ccctacaggt gacgacagaa gacttgggga gttggtcctt
     3661 ggaccatatg acaacacagt tgtcttggag gagcttaggg caggcactac atatagagtc
     3721 aatgtttttg ggatgttcga tggaggagaa agtttaccac ttgttgggca ggaaatgaca
     3781 accctttctg acacaactgt gacaccattt ctatcttccg ggatggaatg tctcaccaga
     3841 gctgaagcag acattgtgtt gctggtggat gggtcatgga gcattggccg cgcaaatttt
     3901 agaactgtgc gaagcttcat ctctcgtatc gtggaagtct ttgaaatcgg ccccaagaga
     3961 gtacaaattg ctctcgctca gtacagtgga gaccccagaa cagagtggca cctaaacgct
     4021 catagagaca agaagagttt gttacaggct gtggcgaact tgccgtataa gggaggaaac
     4081 accctcacag gcatggcttt gaatttcatt cgccaacaga gcttcaagac tcaagctggc
     4141 atgcggcctc gtgctcgcaa aattggagtt ctcattaccg atggaaaatc acaggatgat
     4201 gtggaggctc catccaagaa gctcaaggat gaaggtgtag agctgtttgc tatcggtatt
     4261 aagaatgctg acgaagttga gttaaagatg attgccactg atccagatga cattcacgca
     4321 tacaatgtgg cagattttga gtcattgtcc aagattgtgg atgacctcac catcaacttg
     4381 tgtaacagtg tcaagggccc tggtgacttg gaagcaccat ctaacttagt tatttcagag
     4441 agaactcatc gttcttttag agtgagctgg acaccccctt ctgacagtgt ggacagatac
     4501 aaggtggaat actatcctgt ctctggaggg aaacgccagg agttttacgt gagtcgacta
     4561 gaaactagca cagtgttgaa ggatctgaag cccgagactg agtatgtggt gaacgtgtat
     4621 tctgtggttg aagatgagta cagtgagcct ctgaagggca cagagaaaac cttgccagtc
     4681 cctgtagtta gcctgaatat ttatgatatt ggccccacca ctatgcatgt gcaatggcag
     4741 cctgtgggag gagctactgg ctacactgta tcataccaac ctacaagatc tccagaagga
     4801 acaaagccca aagagatgcg tgtggggccc acagtgaatg atgtgcagct gaccggcctc
     4861 cttcctaaca cagagtatga ggtcaccgtc caggcagtct tgcatgacct cactagtgaa
     4921 cctgccaaag ctcgggaagc cacattgccc ttacccagac cccaggatgt gaaaatcaga
     4981 gatgtgaccc acagtaccat gaatgtcatc tgggagcctg tgcttggaaa agttcgcaaa
     5041 tacactgtta gatataaaac tccagaagag gagttcaaag aggtggaggt ggacagatca
     5101 aggaccagca ctaccctcaa agacctctcc tctcaaaccc agtacacagt gagcgtttcc
     5161 gcagtgtatg atgagggcac atctcccccg gcgactgctc atgagacaac ccggcctgtt
     5221 ccagccccaa ccaacctaca gtttactgaa gtaactccgg agagttttag gggaacctgg
     5281 gatcacggtg cttcagatgt gtctctctac agaataacct gggcacctgt cggaaaccca
     5341 gataagctgg agaccatctt aaatggagat gaaaatacct tgctgtttga aaatctggac
     5401 cccaacactc tgtatgatgt ctccatcact gccatttatc ccgatgagtc tgaaagcgag
     5461 gacctgagtg gcagcgagcg cacattgcgt ctgataccct taacgacaca agctccaaaa
     5521 agtggtccac ggaacctgca ggtgtacaat gccacatcta acagtttgac tgttaagtgg
     5581 gaccctgcta gtggtcgtgt gcaaaaatac agaatcacct atcagccttc aactggagaa
     5641 ggcaatgagc aaacgaccac agtaggagga cggcagaaca gcgtggtcct gcagaaactg
     5701 aagcccgaca gtccgtacac catcaccgtg tcatcccagt atcctgatgg tgaaggcggc
     5761 cggatgactg gaaggggcaa aactaaacct ctgaataccg tgaggaattt gagagtgtat
     5821 gacccatcta ccagcacttt gagtgttcgc tgggaccatg cagaaggcaa tcctcgccag
     5881 tacaaactct tctatgcccc agccggtggt ccagaagaac tggtaccaat ccctgggaat
     5941 accaactatg ccattcttag gaacctgcag ccagatactc catacactgt cacagtggtt
     6001 cctgtctatg cagaaggtga cggcgggcgc acatcagata ctggaaggac actggtgaga
     6061 ggactggcga gaaatgtcca agtgtataac cctacgccca acagcctcga tgtccgctgg
     6121 gactctgccc cagggccagt gcagcagtac cgcattgtgt actccccagt ggctgggaca
     6181 agaccctcag aatctattgt ggtgccaggg aatacccgca cggtgcatct ggagaggttg
     6241 attcctgaca caccctactc tgtgaacatc gtggctctct actcagatgg agaggggaat
     6301 cccagccctg gccagggccg aacactgcca cggagtggac caagaaatct acgagtcttt
     6361 ggggagacga ccaacagcct ctctgtagcc tgggaccatg ctgacgggcc agttcagcaa
     6421 tacaggatca tctattctcc tatcgtgggc gatccaattg atgaatatac cacagttcca
     6481 ggcaggagaa acaatgtaat actgcagccc ctgcaacctg acactccata taaaattact
     6541 gtcattgcca tttatgagga tggagatggt ggccatctaa ctggaaacgg gaggactgtg
     6601 ggtctgcttc cgcctcagaa catgcacatc tctgacgaat ggtacacaag gttccgagtg
     6661 tcctgggacc cttcaccctc accagtcctt ggatataaaa ttgtgtacaa gccagtgggt
     6721 tccaatgagc ccatggaagc ctttgttgga gaagtgacgt catacacttt acacaacctc
     6781 aatcccagca ctacctatga tgtcagtgtt tatgcacagt atgactctgg actcagcgtt
     6841 cccctcacag atcaaggcac cacgttgtac ttaaatgtga cagatctgaa aacttaccag
     6901 gttggatggg acaccttctg tgtcaaatgg tcacctcacc gggcagcgac ctcttacagg
     6961 ctaaagctga gtcctgccga tggaaccagg ggacaagaaa taacagtgag aggatcagag
     7021 accagtcact gcttcactgg cctctccccg gaggctgagt atggcgttac tgtttttgtg
     7081 cagacaccaa atctcgaggg gccgggtgtc cccatcaaag aacagacgac tgtgaaacca
     7141 acagaggctc ccacagaacc gcccacgcct tcacctcctc ccactatccc acctgcccgt
     7201 gatgtatgca aaggggccaa ggcagatatt gtgttcctga cggatgcctc ttggagtatt
     7261 ggagatgaca attttaacaa agttgtaaaa tttattttta atactgtggg ggcctttgat
     7321 gaaatcagcc ctgctgggat tcaggtttct tttgtgcagt acagtgatga ggtcaagtct
     7381 gaattcaagc tgaacacata caacgataag gctctagccc ttggagccct ccagaacatt
     7441 cggtacagag gaggaaacac aagaacaggc aaggccctca cgtttatcaa ggagaaggtc
     7501 ttgacctggg aaagtggcat gaggaagaat gtcccgaagg tgctagttgt ggtcacagat
     7561 ggccggtcac aggatgaggt gaagaaggca gcctttatca tccagcagtc agggttcagt
     7621 gtattcgttg ttggtgtggc tgatgtggac tacaatgagc tcgccaacat tgccagcaag
     7681 cccagtgaga ggcacgtgtt cattgtggac gactttgaat cttttgagaa gatcgaggac
     7741 aatcttatca catttgtttg tgaaactgcc acttcaagtt gtcctctcgt ctatctggat
     7801 ggctacacat caccaggctt taagatgctt gaagcttaca acctgacaga aaagaacttt
     7861 gcttctgtcc aaggagtctc tttggaatca gggtctttcc ccagctattc agcctacagg
     7921 cttcagaaga atgcctttat caatcagccc acagcagaac tccatccgaa tggactcccc
     7981 ccttcatata cgattatatt attgtttaga cttctcccag aaactcctag tgaccccttt
     8041 gcaatttggc aaattacaga cagagactac agaccacaag ttggagtgat tgcagatcct
     8101 tctagcaaga cactgtcttt ctttaataag gatacaagag gcgaggtaca gactgttaca
     8161 tttgatgcag atgaagcgaa gaccttgttt tatggaagct ttcataaggt ccatattgta
     8221 gtgacctcaa agagtgttaa gatttatatt gactgctatg aaattgtaga aaaagacatc
     8281 aaagaagctg gaaatataac aactgatggc tatgaaattc ttggaaaact tcttaaagga
     8341 gagaggaaat cagccacatt ccaaatccag agctttgaca ttatctgcag cccagtgtgg
     8401 accagtagag acagatgctg tgatattccc tctcggagag atgaagcaaa atgccccgcc
     8461 cttccgaatg cttgcacatg cacacaggac agcgttggcc ctccaggtcc tccaggccct
     8521 gcgggaggac ctggtgccaa aggtcccaga ggtgaaagag gcatcaatgg ggcagttggg
     8581 cccccaggtc ctcgtggaga tactgggcct ccaggacctc agggtcctcc aggccctcag
     8641 ggacccaatg gactctccat tccaggagaa cagggtcgcc agggaatgaa aggtgatgca
     8701 ggagagccag ggcttccagg ccggacagga accccaggat tacctggccc gccaggacca
     8761 atggggccac caggagacag aggtttcact ggaaaagatg gtgcaatggg accgagaggc
     8821 ccacctgggc caccgggaac cccaggctct ccaggagtca cagggccaag tgggaaaccg
     8881 ggaaaacctg gagatcatgg ccgacctggt caatctgggt taaaaggaga aaaaggtgat
     8941 aggggagaca ttgcttccca gaacatgatg cgagctgttg caagacaagt gtgtgaacaa
     9001 ctgatcagtg gccagatgag cagattcaac cagatgctga atcagattcc aaacgattac
     9061 cactcaaatc gaaaccagcc tggcccacca ggacctccag ggccccctgg cagtgctgga
     9121 gccagaggag aaccagggcc ggggggacga ccaggattcc ctggcacgcc tgggatgcaa
     9181 ggacctcagg gcgaacgagg tttgcctgga gagaaaggtg aaaggggtat tgggtcgcaa
     9241 ggaccccgag gacctccagg gcccccaggt ccacaaggtg aatccagaac aggtccacca
     9301 gggtctacag gttcaagagg ccctcctggt ccccctggtc gtccaggaaa ctcaggtatc
     9361 cgaggacccc caggtcctcc tggatattgt gattcatccc agtgtgccag cattccatac
     9421 aacgggcaag gctatccagg ttccggctaa caaactttct aagtctccag tgctgcttac
     9481 agtttgaata catgagaatc ctgtttctga gatgtttgcg cacgtgctta ttagaaaatg
     9541 agtctgtatg gaaatctcac ggcagatatg gttaacgaac tgggtcggca tcacacagga
     9601 gggtggagac tccatactaa cttgaatgac gcaacgggca gtggtgtccg cctgatgctt
     9661 ttcagcagta atgtagaaaa ccatctttta aaaagtccga atgcagctgg gaggagccct
     9721 ggctgtgaag gaggtgccct aataagctac taaccagcag agacacgcca tgttaagaca
     9781 gacgattaac cgggttgaag agaaagaccc cgtgtaaata atcaactaat tgtggcttgt
     9841 acatgatctg tatgtgatcc cgtgtactaa aatttcgtta accactcaac aacccgcttc
     9901 tgcgctaaag cctgctggcc gtttgctctc tgcagtaata acgaacagat ctgatccttt
     9961 cttgcttgtt agcagtgtgt ctgagttcag ggcatgtgac ttctcagcat tctgggtgtg
    10021 tacttttatt tgggtttctt acctgcaatc tttcaaacca aagtttaaaa atcaccgttc
    10081 cttccggttt ggctgtagtc acaggtgttc ctcacccact cactggctgt aactctgctg
    10141 gagacatagc cataggggac acggtggact gtagaaaacc tggtgacagc tcctttcacc
    10201 ccgagatcaa tctctaggcc caaatactct tcatgtcctc agctctcgaa gtcatttgct
    10261 aaccctgatg agtttgaagt catgaacagt tatctgggga tttgccaaaa aaagcctacc
    10321 taggtactgt gtttacaatt ctttggccca atttctgatc cttcccaggt tttgtgcaat
    10381 gattgtgttt actgctggat atttgcgaca cccccacccc cacccccacc ctacccccac
    10441 cgctggcgct ccttattcga tcaccaaatt caccctgcac atgtgcacat ggaaataatc
    10501 ggatcgctgt aatgcaatac atctatttgt ggttgtgaga ttaagactgg agtatcgtca
    10561 cctccagtga tgacttaact tttgctgtgc gtgtgtacct tccaagtcat gctataactg
    10621 taatgttgaa tcggacagag ccttatgtgc ccgagggcgg ggcctacctg cctgaccgcg
    10681 agcccttcat cgtacctgtg gagcctgaga ggacggcaga atacgaggat gactacgggg
    10741 cagatgagcc tgagcagcag caccctgacc acaggcgttg gcggcgagcc ctacgcccag
    10801 gccctgggca atgaacctga gaccacgggt tcaccgaggt gggaggtgtt gggattctca
    10861 ttcacaggtc agacagagca gcagtgacgt tttctcagcg tcgcttcatc cacaagtgct
    10921 cctatctgac tgtagagaat cttgtttctg gaggcagcct agctcgcaac agtctgtaga
    10981 catctttgcc tttgcagtac aaatggtcac aacacaagct tttcacagaa gctgcatgga
    11041 gagaacacac ccagggtgcg ctggggcagc cgagcttctt ggttgccctg caagccctgg
    11101 aaaccagagc agctgtctct tcagaaaggg cctttatctt agaactaatc tgcagttcaa
    11161 ttgcacccca tttccagtca ttccgctcct aaaatcaaaa agaaggggga acagcagctc
    11221 actgtagccg gtcacctatc ttttcttcct cctcttatgc tttagggcat agtcttttta
    11281 acaaccacag accttaagcc tcgtagccga agttattgta tcaactggat actgttccat
    11341 attgctttcg acgtctttgt tgacacacta acatttatgc caaattgcag attattctgc
    11401 cgagatggaa ttgcatgttt gtgttgtata tttagaatga actttttttt ttttttgcag
    11461 aacatgtttc ttagttatca aagcagttgg aaatgtttgc aagactatga acatagagtc
    11521 gctgctttta tattttaact gcagattgtg aatttcactg ccttatatta tttatttctg
    11581 aaacaaaaga ggcatttttc aataaaacta ctgaaaattt ga
//
