LOCUS       NM_017360               2560 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus coilin (Coil), mRNA.
ACCESSION   NM_017360
VERSION     NM_017360.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Krejci,J., Legartova,S. and Bartova,E.
  TITLE     Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by
            Coilin Downregulation and the Accumulation of Cajal Bodies in
            Nucleoli
  JOURNAL   Stem Cells Int 2017, 1021240 (2017)
   PUBMED   28337219
REFERENCE   2  (bases 1 to 2560)
  AUTHORS   Stern,J.L., Zyner,K.G., Pickett,H.A., Cohen,S.B. and Bryan,T.M.
  TITLE     Telomerase recruitment requires both TCAB1 and Cajal bodies
            independently
  JOURNAL   Mol Cell Biol 32 (13), 2384-2395 (2012)
   PUBMED   22547674
REFERENCE   3  (bases 1 to 2560)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2560)
  AUTHORS   Richter,K., Brar,S., Ray,M., Pisitkun,P., Bolland,S., Verkoczy,L.
            and Diaz,M.
  TITLE     Speckled-like pattern in the germinal center (SLIP-GC), a nuclear
            GTPase expressed in activation-induced deaminase-expressing
            lymphomas and germinal center B cells
  JOURNAL   J Biol Chem 284 (44), 30652-30661 (2009)
   PUBMED   19734146
REFERENCE   5  (bases 1 to 2560)
  AUTHORS   Miele,A., Medina,R., van Wijnen,A.J., Stein,G.S. and Stein,J.L.
  TITLE     The interactome of the histone gene regulatory factor HiNF-P
            suggests novel cell cycle related roles in transcriptional control
            and RNA processing
  JOURNAL   J Cell Biochem 102 (1), 136-148 (2007)
   PUBMED   17577209
REFERENCE   6  (bases 1 to 2560)
  AUTHORS   Lemm,I., Girard,C., Kuhn,A.N., Watkins,N.J., Schneider,M.,
            Bordonne,R. and Luhrmann,R.
  TITLE     Ongoing U snRNP biogenesis is required for the integrity of Cajal
            bodies
  JOURNAL   Mol Biol Cell 17 (7), 3221-3231 (2006)
   PUBMED   16687569
REFERENCE   7  (bases 1 to 2560)
  AUTHORS   Hong,S., Ka,S., Kim,S., Park,Y. and Kang,S.
  TITLE     p80 coilin, a coiled body-specific protein, interacts with
            ataxin-1, the SCA1 gene product
  JOURNAL   Biochim Biophys Acta 1638 (1), 35-42 (2003)
   PUBMED   12757932
REFERENCE   8  (bases 1 to 2560)
  AUTHORS   Tucker,K.E., Berciano,M.T., Jacobs,E.Y., LePage,D.F.,
            Shpargel,K.B., Rossire,J.J., Chan,E.K., Lafarga,M., Conlon,R.A. and
            Matera,A.G.
  TITLE     Residual Cajal bodies in coilin knockout mice fail to recruit Sm
            snRNPs and SMN, the spinal muscular atrophy gene product
  JOURNAL   J Cell Biol 154 (2), 293-307 (2001)
   PUBMED   11470819
REFERENCE   9  (bases 1 to 2560)
  AUTHORS   Ferreira,J. and Carmo-Fonseca,M.
  TITLE     The biogenesis of the coiled body during early mouse development
  JOURNAL   Development 121 (2), 601-612 (1995)
   PUBMED   7768196
REFERENCE   10 (bases 1 to 2560)
  AUTHORS   Carmo-Fonseca,M., Ferreira,J. and Lamond,A.I.
  TITLE     Assembly of snRNP-containing coiled bodies is regulated in
            interphase and mitosis--evidence that the coiled body is a kinetic
            nuclear structure
  JOURNAL   J Cell Biol 120 (4), 841-852 (1993)
   PUBMED   7679389
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_017360.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF399643.1, SRR26360172.1799348.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-245               JAXUCZ010000010.1  74286852-74287096
            246-1341            JAXUCZ010000010.1  74294072-74295167
            1342-1428           JAXUCZ010000010.1  74295294-74295380
            1429-1476           JAXUCZ010000010.1  74295629-74295676
            1477-1546           JAXUCZ010000010.1  74297993-74298062
            1547-1635           JAXUCZ010000010.1  74299560-74299648
            1636-2560           JAXUCZ010000010.1  74301424-74302348
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2560
                     /gene="Coil"
                     /note="coilin"
                     /db_xref="GeneID:50998"
                     /db_xref="RGD:62031"
     CDS             1..1710
                     /gene="Coil"
                     /codon_start=1
                     /product="coilin"
                     /protein_id="NP_059056.2"
                     /db_xref="GeneID:50998"
                     /db_xref="RGD:62031"
                     /translation="MAASETVRVRLQFDYPPPATPHCTVFWLLVDLNRCRVVTDLISL
                     IRQRFGFSSGALLGLYLEGGLLPPSESARLVRDNDCLRVKLEDQGLPEALIVSNGGDS
                     NFPCRKSKKRAFKLVEDEETDQGYKYPDKYWKRQEDSGPNEKASDLETKLFPDEVRRT
                     KNKRKSKVAGIPAEEDEEETKKKSSKRKEKCEQKKQTRASKSPKQQTHKEGGSQNCSF
                     PRASYRSSLAKARRRSSTGAKGSPSYLSESESCPDSVSDGHCSVTTMQGVTLSEKLSA
                     ELLKDGATKTAAANRQSSKPSFTFSSGKGKASRASSSSSDSSSESEDQFLVSKNMLEG
                     ASDFLKTTGLFAGQGCSSPGLSLETPGIMGWKPSDSNRGRQAPGPNVPVPTSLGRGWG
                     RGEDFLFGKGLRGRGIRGRGRGRGQTVSCILNRSSESQKQKQLNDILTNSSTVIQNPV
                     ETSKKDYSLLPLLAAAPQVGEKIAFKLLELTSDYSPDVSDYKEGKILSHDPETQQVDI
                     EVLSSLPALKEPGKFDLVYHNENGTEVVEYAVTQEKRITVFWKELIDPRLIIDSSSSI
                     SSK"
     exon            1..245
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            246..1341
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1428
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1476
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1546
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1635
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..2560
                     /gene="Coil"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcagcct ccgagacggt tagggtacga cttcaatttg actacccgcc gccggccact
       61 ccacactgca cggtcttctg gcttctagtt gacctgaaca gatgccgagt tgtcacagat
      121 ctcatcagtc tcatccgcca gcgctttggc ttcagttccg gggcgctcct gggcctctat
      181 ctggaagggg ggcttctgcc cccttccgag agcgcgcgcc tggtgagaga caacgactgc
      241 ctcagggtta agttagaaga ccaaggactc cctgaggctt tgatagtaag caatggcggc
      301 gactctaatt tcccatgtag gaaatcaaag aagcgggctt ttaagttggt ggaggacgag
      361 gagacggacc agggttacaa gtaccctgac aagtactgga agaggcagga ggacagcggc
      421 cctaatgaga aggcctcaga cctggagaca aaactcttcc cagacgaggt gcggcggaca
      481 aagaacaaga gaaaaagcaa agtggcaggc atccctgctg aggaggacga ggaagagacc
      541 aaaaagaagt cttcaaaaag aaaggagaaa tgtgaacaga agaagcagac cagggcctcc
      601 aagtctccca aacaacagac acataaagag ggaggctcac agaactgcag cttccccagg
      661 gcctcctaca gaagcagcct tgctaaagcc cggaggagaa gcagcacagg ggcaaaaggt
      721 agtccaagct acctgtcaga gtctgagtcc tgtccagact cagtcagtga tggccactgc
      781 agtgtcacga cgatgcaggg ggtcacctta tcagagaaac tgtcagctga gctgttgaaa
      841 gacggagcta caaaaactgc agctgccaac agacagtcct caaagcctag cttcaccttc
      901 agctccggca agggcaaggc ctccagagcc tcgtcttcca gttcagactc cagttcagag
      961 tcagaagacc agttcctggt gtccaagaac atgctggagg gcgcatctga cttcttaaag
     1021 acaacaggcc tctttgcagg gcaagggtgt tccagtccag ggctgtcttt ggagactccg
     1081 ggtattatgg gatggaagcc ttctgactca aacagaggca gacaggctcc tggtcccaac
     1141 gtgcctgtcc ccaccagttt gggaagagga tgggggcgag gagaggactt cttgtttggg
     1201 aagggactga ggggccgggg tattcggggc cgagggcgag gtcgaggtca gactgtctcc
     1261 tgtatcttaa atagaagctc tgagagccag aagcagaaac agttaaatga tattctaacc
     1321 aactcatcca cggtgatcca gaatccagta gagacctcca agaaggacta tagtctgtta
     1381 ccactcttag cagctgcccc tcaagtcgga gaaaagattg ccttcaagct tttggaactt
     1441 acatccgact attctcctga tgtctctgac tacaaggaag gaaaaatatt aagccacgat
     1501 ccagagaccc agcaagtgga tattgaagtc ctctcctccc taccggcttt gaaagaacct
     1561 gggaagtttg atttggtcta tcacaatgaa aacggaaccg aggtggtgga atacgctgtg
     1621 acgcaggaga agcggatcac tgtgttctgg aaagagttga tcgatccgag actgattatt
     1681 gactcttcaa gtagcatctc aagtaaataa tgtgtctgca aataccctct gaccttgccg
     1741 ccttgaattc tataattgtt tgtgaccgtg gttatagcct gaagttttta aaaagaaggc
     1801 taaatgttgt ttagactttt tgttatcttc actttaccat attaggaaaa aaaaatctac
     1861 ctcatcattt agagtaacga agttgctagt atgtagatcc ttatttcctt cgggctaagt
     1921 tcagtaaccc atttgaaaaa ccgggtgcag accagtaaga cagtgcgctt gactcctccc
     1981 cacctgtccg gctcccagta gcaatcatca gtaggagttt acagtgccac acccaagaat
     2041 gtgctgtgcg tcttgtcttg tttttaagtc actttaaact actaaggcat gtttcttgac
     2101 ttaattttta acacgtgagc tgttctgtta cgcacagagc atctcccaca ttccacacat
     2161 tttatgcttg ctatcctcga gagttagtgg agttggattt gtcggggcga caggttacag
     2221 agtcctttca catcttccag ctggaaaata cagggccctt aggaccctgt gccgactgca
     2281 gtggggagac atggttgttg tatcatctgg agaagacatg gtctcccaga aggctggcca
     2341 tgaacctcag accaggctgg ggcaagtgac cttgtcacac agtgccagga acttggcttc
     2401 tcatactgaa gtgaggatct taaacagaaa tgtccttttc tgttattatc caccacgaag
     2461 ctaaaggctg aatataaact gcaaattgct ttcttttaat gaaaactcag atccctcctt
     2521 cagccttgca gatttttaaa taaaaccata tcaaactcaa
//
