LOCUS       NM_001033889            2786 bp    mRNA    linear   ROD 12-MAY-2024
DEFINITION  Rattus norvegicus component of oligomeric golgi complex 7 (Cog7),
            mRNA.
ACCESSION   NM_001033889 XM_215051
VERSION     NM_001033889.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2786)
  AUTHORS   Steet,R. and Kornfeld,S.
  TITLE     COG-7-deficient Human Fibroblasts Exhibit Altered Recycling of
            Golgi Proteins
  JOURNAL   Mol Biol Cell 17 (5), 2312-2321 (2006)
   PUBMED   16510524
REFERENCE   2  (bases 1 to 2786)
  AUTHORS   Shestakova,A., Zolov,S. and Lupashin,V.
  TITLE     COG complex-mediated recycling of Golgi glycosyltransferases is
            essential for normal protein glycosylation
  JOURNAL   Traffic 7 (2), 191-204 (2006)
   PUBMED   16420527
REFERENCE   3  (bases 1 to 2786)
  AUTHORS   Loh,E. and Hong,W.
  TITLE     The binary interacting network of the conserved oligomeric Golgi
            tethering complex
  JOURNAL   J Biol Chem 279 (23), 24640-24648 (2004)
   PUBMED   15047703
REFERENCE   4  (bases 1 to 2786)
  AUTHORS   Wu,X., Steet,R.A., Bohorov,O., Bakker,J., Newell,J., Krieger,M.,
            Spaapen,L., Kornfeld,S. and Freeze,H.H.
  TITLE     Mutation of the COG complex subunit gene COG7 causes a lethal
            congenital disorder
  JOURNAL   Nat Med 10 (5), 518-523 (2004)
   PUBMED   15107842
REFERENCE   5  (bases 1 to 2786)
  AUTHORS   Ungar,D., Oka,T., Brittle,E.E., Vasile,E., Lupashin,V.V.,
            Chatterton,J.E., Heuser,J.E., Krieger,M. and Waters,M.G.
  TITLE     Characterization of a mammalian Golgi-localized protein complex,
            COG, that is required for normal Golgi morphology and function
  JOURNAL   J Cell Biol 157 (3), 405-415 (2002)
   PUBMED   11980916
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 2, 2020 this sequence version replaced NM_001033889.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.3415.1,
                                           SRR26643299.4291.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               JAXUCZ010000001.1  185980436-185980711 c
            277-425             JAXUCZ010000001.1  185976720-185976868 c
            426-542             JAXUCZ010000001.1  185976372-185976488 c
            543-711             JAXUCZ010000001.1  185970476-185970644 c
            712-794             JAXUCZ010000001.1  185964966-185965048 c
            795-917             JAXUCZ010000001.1  185963931-185964053 c
            918-1116            JAXUCZ010000001.1  185955528-185955726 c
            1117-1244           JAXUCZ010000001.1  185950508-185950635 c
            1245-1399           JAXUCZ010000001.1  185949097-185949251 c
            1400-1516           JAXUCZ010000001.1  185943467-185943583 c
            1517-1582           JAXUCZ010000001.1  185941079-185941144 c
            1583-1769           JAXUCZ010000001.1  185937233-185937419 c
            1770-1910           JAXUCZ010000001.1  185935943-185936083 c
            1911-1994           JAXUCZ010000001.1  185929671-185929754 c
            1995-2109           JAXUCZ010000001.1  185928427-185928541 c
            2110-2253           JAXUCZ010000001.1  185923720-185923863 c
            2254-2786           JAXUCZ010000001.1  185921058-185921590 c
FEATURES             Location/Qualifiers
     source          1..2786
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..2786
                     /gene="Cog7"
                     /note="component of oligomeric golgi complex 7"
                     /db_xref="GeneID:293456"
                     /db_xref="RGD:1566058"
     exon            1..276
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..2420
                     /gene="Cog7"
                     /EC_number="3.2.1.113"
                     /note="COG complex subunit 7"
                     /codon_start=1
                     /product="conserved oligomeric Golgi complex subunit 7"
                     /protein_id="NP_001029061.1"
                     /db_xref="GeneID:293456"
                     /db_xref="RGD:1566058"
                     /translation="MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKL
                     QLFIQEVNHAVEETSLQALQNMPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTS
                     QSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDIAVISAKLTGMQSS
                     LMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMP
                     QLLAYYYKCHKVQLLATWQELCQRDLPLDRQLTGLYHALLGAWHTQTQWATQVFKNPY
                     EVVTVLLIQTLGALVPSLPMCLSEAVERAGPELELTRLLEFYDTTAHFAKGLEMALLP
                     HLQDHNLVKVVELVDAVYGPYKPYQLKYGDLEESNLLIQISAVPLEHGEVIDCVQELS
                     QSVHKLFGLASAAVDRCAKFTNGLGTCGLLTALKSLFTKYVSHFTNALQSIRKKCKLD
                     DIPPNSLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPR
                     SLAGFQDSILTDKKSPAKNPWQEYNYLQKDNPAEYANLMEILYTLKEKGSSNHNLLSV
                     SRTALTRLNQQAHQLAFDSVFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPL
                     EYISNIGQYIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQGEELPELDNMADNWL
                     GSIARATMQTYCDGILQIPAVTPHSTKQLATDIDYLINVMDALGLQPSRTLQNIATLL
                     KAKPEEYRQVSKGLPRRLAATVATMRGVNY"
     exon            277..425
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            426..542
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            543..711
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            712..794
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            795..917
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1116
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1244
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1399
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1516
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1582
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1769
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1910
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..1994
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2109
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            2110..2253
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2786
                     /gene="Cog7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agattcggcg cgagcgcgct gacgggtcgg caaattacag gcgaggtggg ttcagacagg
       61 agccccaaag gcggtatcgc tcggcaccaa ctcggaggcc gagcgccatg gacttctcca
      121 agttcctggc cgatgacttc gacgtgaagg actggatcaa tgcggccttc agagccggcc
      181 ctaaagacgg ggcggcgggg aaggcggacg gccacgcagc caccctggtg atgaagctgc
      241 agttgttcat ccaggaggtg aaccacgccg tggaggaaac aagtctccaa gcccttcaga
      301 acatgcccaa agtgctccgt gatgtggaag ccctgaagca ggaggcgtct ttcctgaaag
      361 aacaaatgat tcttgtcaaa gaggacatta aaaaatttga gcaggatact tcacagtcca
      421 tgcaggtact ggtagagatt gaccaggtga agtccaggat gcagcttgct gcagaatctc
      481 ttcaggaagc tgacaagtgg agcacgctga gtgctgatat tgaggagacc ttcaaaacgc
      541 aagacatagc tgtgatctct gcaaagctga ctggtatgca gagcagcttg atgatgcttg
      601 tggatacccc agactactca gaaaagtgcg tgcacctgga ggctctgaag aacagactgg
      661 aggccctggc cagcccccag attgtagcag cgttcacctc tcagtccgtg gatcagtcta
      721 aagtattcgt gaaggtgttc actgaaatcg accggatgcc ccagctcctt gcatactact
      781 acaagtgtca caaggtgcag cttttagcaa cctggcaaga gctgtgtcag agggaccttc
      841 cactggaccg gcagctcact ggcctctacc atgccttgct tggggcatgg cacacgcaaa
      901 cccagtgggc cacacaggtt ttcaagaacc cctatgaggt ggtgacagtg ctgctgattc
      961 agaccctggg ggccttggtg ccctccctgc ctatgtgcct cagtgaggct gtggagagag
     1021 cgggaccaga gctggagctc accagactac tggagtttta tgacactact gcccactttg
     1081 ccaaggggct ggaaatggcg ctgctccccc atctccagga ccacaacctg gtgaaagttg
     1141 ttgagctggt ggatgctgta tatggtccgt ataaacccta ccagctgaag tacggtgatc
     1201 tggaggagag caaccttctc atacaaatca gcgcggtgcc tctggaacac ggggaagtga
     1261 ttgactgcgt tcaggagctg agccaatctg tgcacaagct ctttggcttg gcatctgcag
     1321 ctgttgacag atgtgccaaa ttcaccaatg gccttgggac ctgtggactg ctgacagcct
     1381 tgaagtccct ctttaccaag tatgtgtctc acttcaccaa tgctctccag tcgatccgaa
     1441 agaagtgcaa gctggatgat attcctccca actccctgtt ccaggaggat tggaccgctt
     1501 ttcagaactc tgtcaggatc atagccacct gtggagagct cttgcgccag tgtggggact
     1561 ttgagcagca gctggcaaac aggatcctgt ccacagcagg gaagtatttg tctgactcct
     1621 acagccctcg gagcctggca ggttttcagg acagcatctt gacagacaag aagagccctg
     1681 ccaagaaccc atggcaggaa tataattacc tccagaaaga taaccctgct gaatatgcca
     1741 atttaatgga aatactttat accctcaagg agaaggggtc cagtaaccat aacctgctgt
     1801 ctgtgtctcg cacagccctg acccggctga accagcaggc ccaccagctg gctttcgact
     1861 cagtcttcct gcgcatcaaa cagcagctgc tgctcgtctc caggatggat agctggaaca
     1921 cagctggcat tggcgaaacc ctgacagacg atctgcctgc cttcagcctc acacctcttg
     1981 agtacatcag caacattggg cagtacatca tgtccctgcc cctgaatctt gagccatttg
     2041 tgactcaaga ggactctgca ttagagttgg ccttacatgc tgggaagctg ccattccctc
     2101 ctgagcaagg ggaagaactt cctgagttgg acaacatggc tgacaactgg ctgggctcta
     2161 tagctagagc caccatgcag acctattgtg atgggatcct ccagatccca gcggtgaccc
     2221 cgcattccac caagcagctg gctacagaca tcgactatct gatcaacgtg atggacgcac
     2281 tgggcctgca gccatcacgc accctccaga acattgcgac actcttgaag gccaagcccg
     2341 aggagtatag acaagtcagc aaaggccttc cacgccgcct cgcagccaca gtggccacca
     2401 tgcgtggtgt gaattattga ccaatcctga gaggagcacc caggcagggt caggactggt
     2461 gtctctcaga atggattcat tctcagtatc tgccagtgtt ggggctgtgt gtgtgtgtgt
     2521 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt taactgaaag aaaggctata ctccaggcat
     2581 ggtggtacat gtctataatc ccttgggaga caggggcagg aagattactg tgagtttgac
     2641 atcatcctgg actagagtga tacccaatct ctacaagaaa aagaagtaaa tgtaaatgag
     2701 aaataatgta ttatttatca gaaaaaattt ttcagatgat ttttaaaaat aaccttaagt
     2761 aggcttaata aacaccatga aatggg
//
