LOCUS       NM_001108449            2773 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus component of oligomeric golgi complex 4 (Cog4),
            mRNA.
ACCESSION   NM_001108449 XM_001075681 XM_341688
VERSION     NM_001108449.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2773)
  AUTHORS   Richardson BC, Smith RD, Ungar D, Nakamura A, Jeffrey PD, Lupashin
            VV and Hughson FM.
  TITLE     Structural basis for a human glycosylation disorder caused by
            mutation of the COG4 gene
  JOURNAL   Proc Natl Acad Sci U S A 106 (32), 13329-13334 (2009)
   PUBMED   19651599
REFERENCE   2  (bases 1 to 2773)
  AUTHORS   Laufman O, Kedan A, Hong W and Lev S.
  TITLE     Direct interaction between the COG complex and the SM protein,
            Sly1, is required for Golgi SNARE pairing
  JOURNAL   EMBO J 28 (14), 2006-2017 (2009)
   PUBMED   19536132
REFERENCE   3  (bases 1 to 2773)
  AUTHORS   Loh E and Hong W.
  TITLE     The binary interacting network of the conserved oligomeric Golgi
            tethering complex
  JOURNAL   J Biol Chem 279 (23), 24640-24648 (2004)
   PUBMED   15047703
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341688.3, XM_001075681.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2773
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..2773
                     /gene="Cog4"
                     /note="component of oligomeric golgi complex 4"
                     /db_xref="GeneID:361407"
                     /db_xref="RGD:1310549"
     exon            1..178
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..2377
                     /gene="Cog4"
                     /codon_start=1
                     /product="conserved oligomeric Golgi complex subunit 4"
                     /protein_id="NP_001101919.1"
                     /db_xref="GeneID:361407"
                     /db_xref="RGD:1310549"
                     /translation="MADVESPPKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEA
                     VYERLCGEEKVVEKELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTC
                     NLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHIHR
                     YLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAAATKEGDLPQVERF
                     FKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLF
                     EGIARIVETHQPIVETYYGPGRLFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLV
                     QSNLMRNSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEV
                     KQEHQKCLDKLLNNCLLSCTMQELVGFYITMEEYFMRETVNKAVALDTYEKGQLTSSM
                     VDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCNKLRMGFPATTLQD
                     IQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKLSFLVTLNNVEVCSENISTLKKTLE
                     SDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLAELNSSAVKPQVQPWI
                     NTFLSVSHSIEEEEFNDYEANDPWVQQFILSLEQQMAEFKASLSPVIYDSLTGLMTSL
                     VAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLE
                     RVTEILDYWGANSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL"
     exon            179..261
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            262..376
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            377..551
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            552..745
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            746..851
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1009
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1068
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1202
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1321
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1488
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1489..1654
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1717
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1834
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1927
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2011
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2113
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2242
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2773
                     /gene="Cog4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgccgagtg ggcaccaaga tggcggatgt ggaatcccct ccgaagttgt caggagcgcc
       61 tccaccacct gagggggtgg gaggaggtca ctgctccgaa atctccaccg agctcattcg
      121 ctctctgaca gagctgcagg agctggaagc tgtgtacgaa cgactctgcg gcgaagagaa
      181 agtggtggag aaagagctgg atgctctttt ggaacagcaa aacaccattg aaagtaagat
      241 ggtcactctc cacaggatgg gtcccaacct gcagttgatt gagggagatg caaagcaact
      301 ggctgggatg atcaccttta cctgcaacct agctgaaaat gtgtccagca aagtccgtca
      361 gcttgacctg gccaagaacc gcctctatca ggccattcag agagcagatg acatcttgga
      421 cctgaagttc tgcatggatg gagttcaaac tgctttgagg agtgaagatt atgagcaggc
      481 tgcagcccac attcatcgtt acttgtgcct ggacaagtct gtcatagagc tcagtcgaca
      541 aggcaaagaa ggaagcatga ttgatgccaa cctgaaatta ctgcaggaag ctgagcaacg
      601 tcttaaagcc atagtagcag agaagtttgc tgctgctacc aaagaagggg atttgcccca
      661 ggtggagcga ttcttcaaga tcttcccact gctgggttta catgaggatg gactgagcaa
      721 gttctcggaa tacctgtgca aacaggtggc cagtaaggct gaagagaatc tgctcttggt
      781 gctgggatca gacatgagtg atcgaagagc tgcagtcatc tttgcggaca ctctcactct
      841 cctctttgaa gggattgccc gaattgtgga aacccaccaa cccatagtgg agacttacta
      901 tgggccaggg cgactcttta ccctgatcaa atatcttcaa gtagaatgtg acacgcaggt
      961 agagaaggtg gtaaacaagt tcatcaagca aagggactac caccagcagt tccggcttgt
     1021 ccagagtaac ttgatgagaa attctgcaac agaaaaaatt gaaccaaggg agctggaccc
     1081 cgtcttgact gaggttaccc tgatgaatgc tcgaagtgaa ttgtacttac gcttccttag
     1141 gaagaggatc agtgcagatt ttgaggtggg ggactccatg gcttcagaag aagtaaagca
     1201 agagcaccag aagtgcctgg acaaactcct caataactgc ctattgagct gtaccatgca
     1261 ggagctagtt ggcttctata ttaccatgga ggagtacttc atgagagaga ctgtcaataa
     1321 ggctgtggct ctggatacct atgagaaggg ccagttgaca tccagcatgg tggatgatgt
     1381 cttttacatt gttaaaaagt gcattgggcg tgctctgtcc agctctaaca tcgactgtct
     1441 ctgtgccatg atcaaccttg caaccagaga gctggaagct gacttcaggg atgttctatg
     1501 taataagcta agaatgggct tcccagccac caccttacag gacatccagc gtggggtgac
     1561 gagtgccgtg aacatcatgc acagcagcct ccagcaaggc aagtttgaca ccaaaggcat
     1621 cgagagcact gatgaagcca agctgtcctt cctggtgact ctgaataatg tggaagtctg
     1681 cagtgagaac atctcaactc tgaagaagac tctggagagt gactgcacca agctcttcag
     1741 tcagggcatt ggaggggaac aggcccaggc caagtttgac agctgccttt ctgacttagc
     1801 tgctgtgtcc aacaaatttc gagacctctt gcaggaaggg ttggcggagc tcaacagttc
     1861 agcagtcaag ccgcaggtgc aaccttggat caacactttt ctctcagtct cacacagcat
     1921 cgaggaggaa gaattcaacg actatgaggc caatgacccc tgggtacagc agttcatcct
     1981 cagcctagaa cagcagatgg cagagttcaa ggccagcctg tccccggtca tctatgacag
     2041 cctaactggc ctcatgacca gccttgttgc tgttgaactg gaaaaagtgg ttctgaaatc
     2101 caccttcaac aggctaggtg gtctgcagtt tgacaaggaa ctccggtcac tcattgctta
     2161 ccttaccact gtgaccacct ggaccatccg agacaagttc gcccggctct cccagatggc
     2221 tacaatcctt aatctagagc gggtgaccga gatactagat tactggggtg ctaactctgg
     2281 ccctttgaca tggcgcctca cccctgctga agtgcgacag gtactggctc tgcgcataga
     2341 cttccgcaat gaggacatca agaggctgcg cctgtagcag ccatgtgagg ccatgtggcc
     2401 caccagtctc agggcctgtt ttctaagtag aactatgcag agctgctggc ttgggtaagc
     2461 cgaaggccca gactgcacca ctgcacggaa accaggaagc aaggagtaca ctcactcact
     2521 gcaaagttct tcccaggagc agtgaaggct ggaggcagag agggctactt tacgatagct
     2581 ttccctacag agaggtgggg actagcaggg agcacacaac ccagccatct atcccatgag
     2641 cagtcactct cacccgcaca ctacagcaca catgctgaca gcatagagag cttggaggct
     2701 cctggtgacc taaaggcaag gctatgatgt tcacaaataa acatcagaat aaagacacta
     2761 cctggagaca tgc
//
