LOCUS       NM_001012157            2874 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus component of oligomeric golgi complex 3 (Cog3),
            mRNA.
ACCESSION   NM_001012157 XM_341356
VERSION     NM_001012157.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2874)
  AUTHORS   Starr T, Sun Y, Wilkins N and Storrie B.
  TITLE     Rab33b and Rab6 are functionally overlapping regulators of Golgi
            homeostasis and trafficking
  JOURNAL   Traffic 11 (5), 626-636 (2010)
   PUBMED   20163571
REFERENCE   2  (bases 1 to 2874)
  AUTHORS   Shestakova A, Zolov S and Lupashin V.
  TITLE     COG complex-mediated recycling of Golgi glycosyltransferases is
            essential for normal protein glycosylation
  JOURNAL   Traffic 7 (2), 191-204 (2006)
   PUBMED   16420527
REFERENCE   3  (bases 1 to 2874)
  AUTHORS   Loh E and Hong W.
  TITLE     The binary interacting network of the conserved oligomeric Golgi
            tethering complex
  JOURNAL   J Biol Chem 279 (23), 24640-24648 (2004)
   PUBMED   15047703
REFERENCE   4  (bases 1 to 2874)
  AUTHORS   Loh E and Hong W.
  TITLE     Sec34 is implicated in traffic from the endoplasmic reticulum to
            the Golgi and exists in a complex with GTC-90 and ldlBp
  JOURNAL   J Biol Chem 277 (24), 21955-21961 (2002)
   PUBMED   11929878
REFERENCE   5  (bases 1 to 2874)
  AUTHORS   Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE,
            Heuser JE, Krieger M and Waters MG.
  TITLE     Characterization of a mammalian Golgi-localized protein complex,
            COG, that is required for normal Golgi morphology and function
  JOURNAL   J Cell Biol 157 (3), 405-415 (2002)
   PUBMED   11980916
REFERENCE   6  (bases 1 to 2874)
  AUTHORS   Suvorova ES, Kurten RC and Lupashin VV.
  TITLE     Identification of a human orthologue of Sec34p as a component of
            the cis-Golgi vesicle tethering machinery
  JOURNAL   J Biol Chem 276 (25), 22810-22818 (2001)
   PUBMED   11292827
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083901.1.
            
            On Feb 11, 2005 this sequence version replaced XM_341356.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083901.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2874
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q11"
     gene            1..2874
                     /gene="Cog3"
                     /note="component of oligomeric golgi complex 3"
                     /db_xref="GeneID:361073"
                     /db_xref="RGD:1304555"
     exon            1..253
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..2566
                     /gene="Cog3"
                     /codon_start=1
                     /product="conserved oligomeric Golgi complex subunit 3"
                     /protein_id="NP_001012157.1"
                     /db_xref="GeneID:361073"
                     /db_xref="RGD:1304555"
                     /translation="MAEASLLLLPEAAAERDAREKLSLWDRRPDSIAPLTDRQTDSVL
                     ELKAAVENLPVPAELPIEDVCSLASQSLPIELTAVVPESTEDVLLKGFTSLGMEEERI
                     ETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILSDVNSALQHLESLQK
                     QYLFVSNKTGTLHEACEQLLKEQSELADLAEHIQQKLSYFNELETINTKLNSPTLSVN
                     SEGFIPMLAKLDDCITYISSHPNFKDYPVYLLKFKQCLSKALHLMKTYTVNTLQTLTN
                     QLLKRDPSSVPNADNAFTLFYVKFRAAAPKVRTLIEQIEQRSEKIPEYQHLLNDIHQC
                     YLDQRELLLGPSIAYTVTELTSQNNRDHCALVRSGCAFMVHVCQDEHQLYNEFFTKPT
                     SKLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILKNEVLEDHVQNNAEQLGAFA
                     AGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKK
                     TPSEASFSDVRLEEGESSSLRKSGSTDSLNPRPQTTISPADLHGMWYPTVRRTLVCLS
                     KLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKTQIDGQLFLIKHLLILREQIA
                     PFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHY
                     LDSKKDVDRHLKSACEQFIQQQTRLFVEPLEEFMTKVSALKTMASQGGPKYTLSQQPW
                     AQPAKVNDLVATAYKTIKTKLPQTLRSMSLYLSNKDTEFILFKPVRNNIQQVFQKFHA
                     LLKEEFSPEDIQIIACPSVEQLNLLLSVSK"
     exon            254..400
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            401..462
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            463..628
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            629..703
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            704..796
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            797..922
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1003
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1047
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1174
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1266
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1406
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1567
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1673
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1798
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1888
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..2009
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2098
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..2233
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2234..2309
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2437
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2438..2536
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2851
                     /gene="Cog3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccccggtcct cccggaagtt ccccggctct gcctgtcggg ctccggttct gcgttgctga
       61 ggggcccaag gcggcgggga tggcggaggc gtcgctgctg ctgctgcccg aggcggcggc
      121 cgagcgggac gcccgcgaga agctgtctct ctgggatcgg agacccgact cgatagcgcc
      181 gctgacagac aggcagacgg actcggtgct ggagctaaag gcggcagtgg agaacctgcc
      241 ggtgccggcc gagctcccaa ttgaagatgt atgcagttta gcatcccagt cgctgcccat
      301 tgagctgact gctgtagtgc ctgaatctac agaagacgtc ctcttaaagg gcttcacatc
      361 tttaggaatg gaagaagaaa gaattgagac tgcacagcag tttttctcat ggtttgcaaa
      421 gctgcaaact caaatggatc aggatgaagg aactaaatat agacagatga gggattactt
      481 gtctgggttt caggaacagt gtgatgctat actgagtgac gtgaacagtg ctcttcagca
      541 cctggagtcc ctgcagaaac agtatctgtt tgtgtccaac aagacaggaa cacttcacga
      601 agcctgtgaa cagctcctaa aagagcagtc ggaacttgct gatcttgctg agcacatcca
      661 acagaagctg tcttatttta atgagttgga gaccattaac acaaaattga attccccaac
      721 gttgtctgtg aatagtgaag gatttatccc tatgctggcc aagttagatg attgtataac
      781 atatatttca tctcatccta attttaaaga ttatcctgta tacttactga agtttaaaca
      841 atgtctttct aaagctttgc acctcatgaa gacatatact gtgaacacac tgcagactct
      901 cacaaatcag ttactaaaaa gggacccctc atcagtccct aatgcagaca atgccttcac
      961 actattttat gtgaaatttc gagctgctgc ccctaaagtc agaactctca ttgaacaaat
     1021 agagcaacgt tctgagaaga tacccgaata ccagcacctg ctcaatgata tccaccagtg
     1081 ttaccttgat cagcgggagc tccttttggg cccaagtatt gcctacactg tcacggagct
     1141 aaccagccag aacaacagag accattgtgc cttggttcgc agtggctgtg cctttatggt
     1201 ccatgtctgc caagatgagc accaacttta caatgaattt tttacaaagc caacatcaaa
     1261 attagacgaa ctgttggaga aactgtgcgt gtcactgtat gacgtgttcc ggccgttgat
     1321 catccacgtc attcacctag agactctgtc tgagctctgt gggattctta aaaatgaggt
     1381 gcttgaagac catgtacaga acaacgctga acagctgggg gcctttgcag ctggagtaaa
     1441 gcagatgttg gaagatgtac aagagaggct tgtgtatcgc acccatatct acattcagac
     1501 ggacatcaca ggctataaac cagctcctgg agacctggcg taccctgata agcttgtcat
     1561 gatggagcaa attgcacaga gtttaaagga tgaacagaag aagacacctt cagaagcttc
     1621 cttttcagat gtacggttag aagaaggaga gtccagtagt ttaagaaagt ctggttcaac
     1681 agactccctc aatcctagac cacagaccac gatttctcca gcagatcttc acgggatgtg
     1741 gtatcccaca gttcgaagga cacttgtctg tctctccaaa ttatatagat gcatagatag
     1801 ggcggtgttc caaggattat cacaggaagc cttgtctgct tgcatacagt ccttgctagg
     1861 agcatcagag tctatcagca aaaacaagac tcagattgat ggacaacttt tcttaattaa
     1921 gcaccttttg attcttcgag aacaaattgc tccatttcac actgaattca ccattaagga
     1981 aatttccctg gacctcaaga aaactcgaga tgcagcattt aaaatcctga accctatgac
     2041 tgttccgaga ttttttaggc tgaatagcaa caatgccttg atagagttct tgttggaggg
     2101 aactcctgag atcagagagc attatcttga ctctaagaag gacgtggatc ggcacctgaa
     2161 gtcagcctgt gagcagttca ttcagcaaca gaccaggcta tttgtagagc cactggagga
     2221 gttcatgaca aaggtatcag cattaaaaac catggccagt cagggaggcc ccaagtacac
     2281 cctctcacag cagccttggg cacaaccagc gaaggtcaac gaccttgtgg ccactgctta
     2341 caagacaata aaaacgaagc tgccgcagac attgagaagc atgtctctgt acttgtccaa
     2401 taaggacacg gagttcatct tgtttaagcc tgtcaggaat aacattcagc aagtcttcca
     2461 gaagttccat gctctgctaa aggaagagtt cagtcctgaa gatatccaga ttattgcttg
     2521 tccttctgtg gaacagctaa acctcctgct gtcagtctct aagtagtcct ctggactgtg
     2581 ggtgtcagcg atctgtccca cggataggcc tgagggtcct gcagcctgca ggatgcccaa
     2641 ggcccctgtg tgggacggct cctgggaaca tggatggctg cctgcagaag ggaacctggg
     2701 tgaagcagaa gatcaaaatg ccaaagattg acagcaggga tagctgcctt gttgaaatgg
     2761 tctccagaag tggagagact cgacagggag ccctggttca cagtgaaatg ttccttcaca
     2821 cagattgtgc aataaagtag gctaccataa aaaaaaaaaa aaaaaaaaaa aaaa
//
