LOCUS       NM_053746               3341 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus contactin 5 (Cntn5), mRNA.
ACCESSION   NM_053746 XM_346816
VERSION     NM_053746.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3341)
  AUTHORS   Ashrafi,S., Betley,J.N., Comer,J.D., Brenner-Morton,S., Bar,V.,
            Shimoda,Y., Watanabe,K., Peles,E., Jessell,T.M. and
            Kaltschmidt,J.A.
  TITLE     Neuronal Ig/Caspr recognition promotes the formation of axoaxonic
            synapses in mouse spinal cord
  JOURNAL   Neuron 81 (1), 120-129 (2014)
   PUBMED   24411736
REFERENCE   2  (bases 1 to 3341)
  AUTHORS   Shimoda,Y., Koseki,F., Itoh,M., Toyoshima,M. and Watanabe,K.
  TITLE     A cis-complex of NB-2/contactin-5 with amyloid precursor-like
            protein 1 is localized on the presynaptic membrane
  JOURNAL   Neurosci Lett 510 (2), 148-153 (2012)
   PUBMED   22285261
REFERENCE   3  (bases 1 to 3341)
  AUTHORS   Toyoshima,M., Sakurai,K., Shimazaki,K., Takeda,Y., Nakamoto,M.,
            Serizawa,S., Shimoda,Y. and Watanabe,K.
  TITLE     Preferential localization of neural cell recognition molecule NB-2
            in developing glutamatergic neurons in the rat auditory brainstem
  JOURNAL   J Comp Neurol 513 (4), 349-362 (2009)
   PUBMED   19177518
  REMARK    GeneRIF: findings suggest that NB-2 plays a key role in maturation
            of glutamatergic synapses in the brainstem during the final stages
            of auditory development
REFERENCE   4  (bases 1 to 3341)
  AUTHORS   Li,H., Takeda,Y., Niki,H., Ogawa,J., Kobayashi,S., Kai,N.,
            Akasaka,K., Asano,M., Sudo,K., Iwakura,Y. and Watanabe,K.
  TITLE     Aberrant responses to acoustic stimuli in mice deficient for neural
            recognition molecule NB-2
  JOURNAL   Eur J Neurosci 17 (5), 929-936 (2003)
   PUBMED   12653969
REFERENCE   5  (bases 1 to 3341)
  AUTHORS   Ogawa,J., Lee,S., Itoh,K., Nagata,S., Machida,T., Takeda,Y. and
            Watanabe,K.
  TITLE     Neural recognition molecule NB-2 of the contactin/F3 subgroup in
            rat: Specificity in neurite outgrowth-promoting activity and
            restricted expression in the brain regions
  JOURNAL   J Neurosci Res 65 (2), 100-110 (2001)
   PUBMED   11438979
REFERENCE   6  (bases 1 to 3341)
  AUTHORS   Ogawa,J., Kaneko,H., Masuda,T., Nagata,S., Hosoya,H. and
            Watanabe,K.
  TITLE     Novel neural adhesion molecules in the Contactin/F3 subgroup of the
            immunoglobulin superfamily: isolation and characterization of cDNAs
            from rat brain
  JOURNAL   Neurosci Lett 218 (3), 173-176 (1996)
   PUBMED   8945756
  REMARK    Erratum:[Neurosci Lett 1997 Jan 17;221(2-3):217]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from D87212.1.
            
            On Dec 17, 2003 this sequence version replaced XM_346816.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D87212.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3341
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q11"
     gene            1..3341
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /note="contactin 5"
                     /db_xref="GeneID:114589"
                     /db_xref="RGD:621302"
     exon            1..76
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..3321
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /function="neural adhesion molecule"
                     /note="neural recognition molecule NB-2"
                     /codon_start=1
                     /product="contactin-5 precursor"
                     /protein_id="NP_446198.1"
                     /db_xref="GeneID:114589"
                     /db_xref="RGD:621302"
                     /translation="MASSWRLILFLSFTSCLSEYSEALSGLSTSYAALLRIKKSSTSS
                     AFGSKSRPRYSSPSLGTLSVSPPSWRGAAQQYHSPVNLYHSPDAFRQDESVDYGPVFV
                     QEPDDIIFPTDSDEKKVALNCEVRGNPSPTYRWLRNGTEIDLESDYRYSMIDGTFIIN
                     NPSESRDSGLYQCLATNTFGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCS
                     PPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNAVT
                     NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPTTVTAAKGTTVKMECFALGNPVPTITW
                     MKVNGYIPSKSRLRKSQAVLEIPNLQLDDAGIYECTAENSRGKNSFRGQLQIYTYPHW
                     VQKLNDTQLDSGSPLQWECKATGKPRPTYRWLKNGAPLLPQSRVDTANGVLAIHSVNQ
                     SDAGMYQCLAENKYGAIYASAELKILASPPSFELNQVKKSIIVTKDREVLIECKPQGS
                     PKPAISWRKGDKAVRGNKRIAILPDGSLRILNASKADEGKYICQGVNIFGSAEIIASV
                     SVKEPTRIELTPKRTELTVGESIVLNCKAMHDSSLDVTFYWTLKGQPIDFEKEGGHFE
                     SIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGVVIVEEI
                     TESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTVPEVITGDMESAMAVDLNP
                     WVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSNVSGGSGRRHELVIAWEPVS
                     EEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSDASKFIYRDESVPPLTPFEVKVGVYNN
                     KGDGPFSQIVVICSAEGEPTAAPTDVTATSVSVSEIFVVWKHVKESLGRPQGFEIGYW
                     KDTEPEDSAETVRTRGNESFVMLTGLEGDTLYHLTVRAYNGAGYGPPSREVSATTKRH
                     PPSEPPGNLRWEQQGSQVSLGWEPVRPLANESEVMGYKVFYRQEGHSKGQVIETQKPQ
                     AVVPLPEAGVYIIEVRAYSEGGDGTASSQIRVPSYAGGKITSAQSTLHSLSKWSSVTL
                     LLALMLPSSSW"
     exon            77..298
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            299..422
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            423..598
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            599..694
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            695..898
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1001
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1183
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1320
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1450
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1601
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1729
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1905
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2026
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2185
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2186..2335
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2406
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..2641
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2642..2751
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2752..2938
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..3051
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3052..3220
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3221..3341
                     /gene="Cntn5"
                     /gene_synonym="Nb-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaagagtcc agtgaccaat catggcttcc tcttggagac taatcctgtt cctgtctttc
       61 acaagttgtc tttcagaata ctctgaagct ctctctggcc tttctacttc atatgctgct
      121 ttgctaagaa ttaagaagag ttcaacctca tctgccttcg gttccaagtc cagaccacga
      181 tacagcagtc cttcattagg caccctcagt gtttctccac cgagctggcg aggggcagct
      241 cagcagtacc actccccggt taacctttac cactccccag atgccttcag acaggatgaa
      301 agtgtggatt atgggccagt atttgtgcaa gagcctgatg atattatttt tccaactgat
      361 tctgatgaaa agaaggtagc cctgaattgt gaagttcgtg gcaacccatc tcctacttac
      421 agatggcttc ggaatggaac agaaattgat cttgagagtg actaccgcta cagtatgata
      481 gacggcacct tcatcatcaa caatccaagt gaaagcaggg attcagggct ctaccagtgt
      541 ttagccacca acacgtttgg aagtattctc agtcgagaag ccacacttca gtttgcttat
      601 ctggggaatt ttagtggccg gacaagaagt gcagtctcag tgcgggaagg ccagggggtt
      661 gttctgatgt gctctccacc gcctcattct ccagagatca tctatagctg ggtcttcaat
      721 gagttccctt ccttcgtggc agaggacagc cggcggttca tatcccaaga gacaggcaac
      781 ctctatattt ctaaagtgca aacatcagat gttggcagct acatttgtct ggtgaaaaat
      841 gctgtaacga atgctcgcgt gctcagccct ccaaccccgc tcacgcttcg aaatgatggt
      901 gtaatgggag aatacgagcc aaaaattgag gtccattttc ccaccacggt cacagctgct
      961 aagggaacga ctgtgaagat ggaatgcttt gcacttggca accctgttcc aacgatcact
     1021 tggatgaagg ttaacggtta cattcccagt aagtccagac tgcgaaaatc ccaggcggtc
     1081 ctggagatcc ccaacctgca gctggatgac gccggaatat atgaatgcac agctgaaaac
     1141 tcccgaggga aaaactcctt tcgtggacag ctccaaatat acacgtaccc acactgggta
     1201 cagaaactga atgacaccca gctggacagt gggagtcctc tgcagtggga atgcaaggct
     1261 accggaaagc ccaggcccac ataccgctgg ctgaagaatg gagcacccct cctgccacag
     1321 agcagagtgg acacagctaa tggagtattg gcgatccata gtgtaaatca atcagatgct
     1381 gggatgtatc agtgtttggc tgagaataaa tatggagcta tttatgcgag cgccgagctg
     1441 aagattttag cctcaccacc ctcttttgaa ctgaatcaag tgaagaaatc aataattgtc
     1501 acgaaagacc gggaagtgct catagaatgc aaaccccagg gctctccaaa gccagccatc
     1561 tcctggagga agggagacaa ggcagtgagg gggaacaaga gaatagctat tcttccagac
     1621 ggaagcctgc ggatcctcaa tgcttctaaa gcggatgagg ggaagtacat ttgccaaggg
     1681 gtgaacatct tcggttccgc ggagatcata gcttctgtgt ctgtcaaaga acccacaagg
     1741 atagagctta ctcctaaaag aacagagtta actgttggag agagcattgt ccttaactgc
     1801 aaagccatgc acgactccag tttggatgtc actttctact ggacactaaa aggacaacct
     1861 attgattttg agaaagaagg cggacatttt gaaagcatca gggctcaagc atcctctgca
     1921 gatttaatga tcaggaacat ccttctgatg catgctggga gatatggctg cagggtacag
     1981 accacagcag acagtgtgtc agatgaggca gaacttcttg ttaggggtcc cccagggcca
     2041 cctggagtgg tcatagtgga ggagatcaca gaaagcacag ccactctctc atggagtcca
     2101 gcaactgaca accacagccc catctcttcc tacaaccttc aggctcgcag ccccttctcc
     2161 ctgggctggc aaacagtgaa gacagtccct gaagtcatca caggagacat ggagtcagcg
     2221 atggctgtgg acctaaaccc ctgggtagaa tatgaattcc gagtggtggc caccaatcca
     2281 attgggacag gagatccaag cattccatct cgaatgatcc gcacaaacga ggcagttcct
     2341 aagacggcac ccagcaacgt gagtggagga agtggaagaa ggcacgagtt ggtcattgcc
     2401 tgggagccag tatcagaaga gtttcagaat ggggaaggct tcggctacat agtggcattc
     2461 agaccgaatg gaacacgtgg ctggaaggag aaaatggtta cttcttcgga tgcttccaag
     2521 ttcatttacc gagacgaaag tgtccctcct ctcacaccct ttgaagtcaa agttggtgtc
     2581 tataataata aaggtgatgg gcctttcagc cagattgtag tcatctgctc ggctgaggga
     2641 gaacccactg ctgctcccac tgatgtcaca gcgaccagtg tgtcggtgtc agagattttt
     2701 gttgtatgga aacatgttaa agagagtctc ggaagaccac aggggtttga gattggttac
     2761 tggaaagata ccgagccaga agactctgca gaaacagtca gaaccagagg gaatgagtca
     2821 ttcgtcatgt tgacgggatt ggaaggcgac acactctatc acctcacagt cagggcttac
     2881 aatggagccg ggtatgggcc acccagcagg gaagtgagcg ccaccaccaa gaggcacccc
     2941 cctagcgaac cacctggcaa cctccgttgg gaacagcagg gttcccaggt ttccctaggc
     3001 tgggagcctg tcagacctct agccaacgag tctgaagtca tgggttacaa ggttttttat
     3061 aggcaagagg gtcacagcaa aggtcaagtt attgagacac agaaacctca ggctgttgtg
     3121 cctctccctg aggctggagt ctacattatt gaagttcgag cgtacagtga aggaggagat
     3181 ggaacagcga gctcccaaat cagggtacct tcatatgcag gtgggaaaat cacaagcgct
     3241 cagtccaccc tgcactctct ctccaagtgg tcctcagtaa cactgctctt ggctttgatg
     3301 cttccttcca gttcctggtg aaagcagctc acgcagtgtg c
//
