LOCUS       NM_053879               4609 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus contactin 4 (Cntn4), mRNA.
ACCESSION   NM_053879 XM_579581
VERSION     NM_053879.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4609)
  AUTHORS   Radom,J., Colin,D., Thiebault,F., Dognin-Bergeret,M.,
            Mairet-Coello,G., Esnard-Feve,A., Fellmann,D. and Jouvenot,M.
  TITLE     Identification and expression of a new splicing variant of
            FAD-sulfhydryl oxidase in adult rat brain
  JOURNAL   Biochim Biophys Acta 1759 (5), 225-233 (2006)
   PUBMED   16806532
REFERENCE   2  (bases 1 to 4609)
  AUTHORS   Fernandez,T., Morgan,T., Davis,N., Klin,A., Morris,A., Farhi,A.,
            Lifton,R.P. and State,M.W.
  TITLE     Disruption of contactin 4 (CNTN4) results in developmental delay
            and other features of 3p deletion syndrome
  JOURNAL   Am J Hum Genet 74 (6), 1286-1293 (2004)
   PUBMED   15106122
REFERENCE   3  (bases 1 to 4609)
  AUTHORS   Singh,D. and Lampe,P.D.
  TITLE     Identification of connexin-43 interacting proteins
  JOURNAL   Cell Commun Adhes 10 (4-6), 215-220 (2003)
   PUBMED   14681019
REFERENCE   4  (bases 1 to 4609)
  AUTHORS   Hansford,L.M., Smith,S.A., Haber,M., Norris,M.D., Cheung,B. and
            Marshall,G.M.
  TITLE     Cloning and characterization of the human neural cell adhesion
            molecule, CNTN4 (alias BIG-2)
  JOURNAL   Cytogenet Genome Res 101 (1), 17-23 (2003)
   PUBMED   14571131
REFERENCE   5  (bases 1 to 4609)
  AUTHORS   Yoshihara,Y., Kawasaki,M., Tamada,A., Nagata,S., Kagamiyama,H. and
            Mori,K.
  TITLE     Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and
            F3: four members of an axon-associated cell adhesion molecule
            subgroup of the immunoglobulin superfamily
  JOURNAL   J Neurobiol 28 (1), 51-69 (1995)
   PUBMED   8586965
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053879.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U35371.1, SRR26643298.24325.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000004.1  140180821-140180944
            125-269             JAXUCZ010000004.1  140335464-140335608
            270-325             JAXUCZ010000004.1  140413812-140413867
            326-473             JAXUCZ010000004.1  140655274-140655421
            474-600             JAXUCZ010000004.1  140827866-140827992
            601-776             JAXUCZ010000004.1  140835274-140835449
            777-872             JAXUCZ010000004.1  140904534-140904629
            873-1070            JAXUCZ010000004.1  140961156-140961353
            1071-1173           JAXUCZ010000004.1  140978310-140978412
            1174-1358           JAXUCZ010000004.1  140981482-140981666
            1359-1495           JAXUCZ010000004.1  140993558-140993694
            1496-1625           JAXUCZ010000004.1  140995420-140995549
            1626-1776           JAXUCZ010000004.1  141016586-141016736
            1777-1904           JAXUCZ010000004.1  141091911-141092038
            1905-2080           JAXUCZ010000004.1  141136126-141136301
            2081-2201           JAXUCZ010000004.1  141142938-141143058
            2202-2360           JAXUCZ010000004.1  141147715-141147873
            2361-2510           JAXUCZ010000004.1  141150289-141150438
            2511-2581           JAXUCZ010000004.1  141152102-141152172
            2582-2816           JAXUCZ010000004.1  141153253-141153487
            2817-2929           JAXUCZ010000004.1  141155794-141155906
            2930-3116           JAXUCZ010000004.1  141157108-141157294
            3117-3229           JAXUCZ010000004.1  141157729-141157841
            3230-3398           JAXUCZ010000004.1  141172665-141172833
            3399-4609           JAXUCZ010000004.1  141175980-141177190
FEATURES             Location/Qualifiers
     source          1..4609
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q41"
     gene            1..4609
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /note="contactin 4"
                     /db_xref="GeneID:116658"
                     /db_xref="RGD:621361"
     exon            1..124
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            125..269
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            270..325
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            326..473
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             419..3499
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /note="brain-derived immunoglobulin superfamily protein 2;
                     axonal-associated cell adhesion molecule"
                     /codon_start=1
                     /product="contactin-4 precursor"
                     /protein_id="NP_446331.1"
                     /db_xref="GeneID:116658"
                     /db_xref="RGD:621361"
                     /translation="MRLPWELLVLQSFMLCLADDYTLHGPVFVQEPSHVMFPLDSEEK
                     KVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDSGTYQCIA
                     TNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFN
                     EHPSYQDNRRFVSQETGNLYIAKVEKADVGNYTCVVTNTVTSHQVLGPPTPLILRNDG
                     VMGEYEPKIEVQFPETVPAEKGSTVKLECFALGNPVPTILWRRADGKPIARKARRHKS
                     SGILEIPNFQQEDAGSYECVAENSRGKNIAKGQVTFYAQPNWVQIINDIHVAMEESVF
                     WECKANGRPKPTYRWLKNGDPLLTRERIQIEQGTLNITIVNLSDAGMYQCVAENKHGV
                     IYASAELSVIAESPDFSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRE
                     NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNVVVKDPTKVMVPPSSMD
                     VTVGESIVLPCQVTHDHSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNI
                     QLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNH
                     SPITMYVIQARTPFSVGWQAVSTVPELVDGKTFTATVVGLNPWVEYEFRTVAANVIGI
                     GEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFR
                     PHGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAE
                     EEPTKPPASIFARSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENARKIRTV
                     GNQTSTKITNLKGNALYHLSVKAYNSAGTGPSSAAVNVTTRKPPPSQPPGNIIWNSSD
                     SKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEI
                     KPFSDGGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIMISLTARSSL"
     exon            474..600
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            601..776
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            777..872
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1070
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1173
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1358
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1495
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1625
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1776
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1904
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2080
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2201
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2360
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2510
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2581
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..2816
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2817..2929
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..3116
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3117..3229
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3230..3398
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3399..4609
                     /gene="Cntn4"
                     /gene_synonym="Axcam; Big-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagagcacta ggttcataac caggattggt cgcaagtagg gagcttttgc cactccgctg
       61 ggaccttcgg acgctggctg tgttgcaagc ccagttctcc taagcgctgt gccgggcgtc
      121 ttggattcat attgtgttgt cggcacttct cccaggtgga tttcagctag agctcacttg
      181 gaaatgtctg cagcttggtg tgagagaata ggattcttct tgctgaacta aaggaagcaa
      241 ccttcatacg ttcctactga aaagaaaggg gatttttgac acagagtaaa tccatagtat
      301 atgcctctcc gaactgtcct gaaagattaa aggttgcaca aagcttaaaa ggaacagaag
      361 cagcagttct attcacttgt tattggactt gaaactcctt tgacctcgga agctgaagat
      421 gaggttgcca tgggaactgc tagtgctgca atcattcatg ttgtgccttg cagatgacta
      481 cacactacat ggcccagttt ttgttcaaga gccaagtcat gtcatgtttc ctttggattc
      541 tgaggagaaa aaagtgaaac tgagttgcga agttaaaggg aatccaaagc ctcacatcag
      601 gtggaagtta aatggaacag atgttgacat tggtatggat ttccgctaca gtgttgttga
      661 aggcagcttg ttgatcaata accccaataa aacccaagat tctggaacgt accaatgcat
      721 agcaacaaac tcgtttggaa caattgtaag cagagaagca aagcttcagt ttgcatatct
      781 tgaaaacttt aagacaagaa caagaagcac agtgtcagtc cgtcgaggtc agggaatggt
      841 cctcctgtgc ggcccgccac cccattctgg agagctgagc tacgcctgga tcttcaatga
      901 acacccttcc tatcaggata accgccgctt tgtttctcaa gagactggca atctgtatat
      961 tgccaaggtg gaaaaagctg acgttggtaa ttatacgtgt gtggttacca atactgtgac
     1021 cagccaccag gtcctgggac cgcctacacc actaatcctg agaaatgatg gggtgatggg
     1081 tgaatatgaa cccaaaatag aagtacagtt tccagaaact gtcccggctg agaaaggatc
     1141 aacagtcaag ctggaatgct ttgccttagg aaacccagtc ccaactattc tatggagaag
     1201 agctgatggg aagccgatag caaggaaagc cagaagacac aagtccagtg gaattctgga
     1261 aattcccaat tttcagcagg aagatgctgg ttcctatgaa tgtgtggccg aaaactccag
     1321 aggcaaaaac atagcaaagg gacaggtgac tttttatgct caacctaact gggttcaaat
     1381 aataaatgat atccacgtgg ccatggaaga gagtgtcttc tgggaatgta aagcaaatgg
     1441 gaggcccaag cctacctata ggtggcttaa aaatggtgac ccactgttaa cacgggagag
     1501 aatacagatc gagcaaggaa cactcaacat aacaatagtg aatctctcag atgccggcat
     1561 gtaccagtgt gtggcagaga ataaacatgg agttatctat gccagcgctg aacttagtgt
     1621 aatagctgaa agtccagatt tttcgagaac actcttaaaa agagtaacac ttgtcaaagt
     1681 gggtggtgaa gttgtcattg agtgcaagcc gaaagcatcc ccaagacctg tctacacctg
     1741 gagaaaggga agagaaatat taagagaaaa tgaaagaatt accatttctg aagatggaaa
     1801 cctcagaatc atcaatgtca ctaagtctga cgctggaagt tatacctgca tagccactaa
     1861 ccattttggc actgccagca gcactgggaa tgtggttgtg aaagacccaa caaaggtgat
     1921 ggttccccct tccagcatgg atgtcactgt gggagaaagc attgttcttc catgccaggt
     1981 gacacatgat cactcactgg acattgtctt tacttggaca tttaatggac acttgataga
     2041 ctttgacaaa gatggagacc actttgaaag agttggaggg caggattcag ctggtgattt
     2101 gatgatccga aacatccaac tgaagcatgc tgggaaatat gtctgcatgg tccaaacaag
     2161 tgtggacaaa ctctctgctg ctgcggacct gattgtaaga ggtcctccag gtcctcctga
     2221 ggctgtgacc atagacgaaa tcacagacac cactgctcag ctgtcctgga gacctggacc
     2281 tgacaaccac agccccatca ccatgtatgt catccaagct aggactccat tctccgtggg
     2341 ctggcaagca gtcagtacag ttccagaact cgttgatggg aagacattca cagcaactgt
     2401 ggtgggtttg aacccctggg ttgaatatga attccgcact gttgcagcta atgtgattgg
     2461 cattggggaa cccagcaggc cctcagagaa acggaggact gaagaggctc tccccgaagt
     2521 caccccggct aacgtcagtg gtggtggagg cagcaagtct gaactggtta taacctggga
     2581 gacagtccct gaggaattac agaatggcag aggctttggt tacgtggtag ccttccggcc
     2641 acatggcaaa atgatctgga tgctgacagt gctggcttca gctgatgcct ccagatacgt
     2701 gttcaggaat gaaagcgtgc gtccattctc tccctttgag gttaaagtgg gtgtcttcaa
     2761 taacaaaggg gaaggccctt tcagtcccac caccctggtg tattctgctg aagaagaacc
     2821 caccaagcca ccagccagta tctttgccag gagtctttct gccacagata tcgaagtttt
     2881 ctgggcctcc cctattggga agaacagggg acggattcaa ggttatgagg taaaatattg
     2941 gagacatgat gataaggaag aaaatgctag aaaaatacga acagttggaa accagacatc
     3001 tacgaaaatc accaacttga aagggaatgc tctgtaccac ctatctgtca aggcttataa
     3061 ctcagctggg acaggaccct ccagtgcagc agtcaatgtc acgaccagaa agccaccacc
     3121 aagccaaccc cctggaaaca tcatatggaa ttcatcggac tccaaaatta tcctgaactg
     3181 ggatcaagtg aaggccctgg ataatgagtc agaagtaaaa ggatacaaag tcttgtaccg
     3241 atggaacagg caaagcagta catctgtcat tgaaacgaac aaaacgtcag tggagctttc
     3301 tctacctttc gatgaagact acatcataga gatcaagcca ttcagtgacg gaggagatgg
     3361 cagcagcagt gagcagatcc gaatcccaaa gatatcaaat tcctatgcaa gaggatctgg
     3421 ggcttctacc tccaatgcgt gtacactgtc agccatcagt acaataatga tttctctcac
     3481 agccaggtct agtttatgac aaaagttatc taaaggactc actatttata atataagcaa
     3541 catttagcta gttgttttga agacacccag tactaagtaa tattgttgtt caagtacatc
     3601 ttattactgg aaaaaaatgt tttttgcttc gttaggaatg gcattataca gtacttcctc
     3661 aaagcaaatc tagctttgtc tgaagtttct ttggaaactc tgcaatgcac tgaagacatc
     3721 tgtaatatga tgttaccaaa gcagtttaca tatgtcctta tatgcatatt ttttattata
     3781 tatttagtgt tttatagaat tttttaaagt taacatataa tgtagatatt gttttttttt
     3841 cttcctctgc tgtaaaatgc tctgggcaac acaaccacac aattatgatt tgagacgatt
     3901 tcctttaagg acagagtttg aaaatcatct cagtagatga attacaattg acttgtacag
     3961 ttttacaagg atctggtgtc aaaacatcta gagactgggt ctgtaactca aggctgctgt
     4021 atataaatta ttccttgaat ggttaatgca ttgaatcgag tccccttgac atatgtgata
     4081 tgttttccca ccctgttgtg aattttgttg ctcaacacaa tttgaaatgg tttcaggagc
     4141 tacacatccc caaaagctaa acttcccagc ccatgaggca ccttgtgcaa tcctcccatc
     4201 cctgaactta gcattgtctg gtaagacttt atttgagcac cgtccttgtg gtagcattat
     4261 cttaggcatt gaatttgaag ttacatatcc tgtagtaaca tagatgaaaa gttactatag
     4321 tcaaatgagt ctttcatggc ataaaaggta attttactct ttagacatat ctgttttgaa
     4381 tgtaaatttt ttaaaactcc tgtcgatgca tttataattt caagatttct tagataccat
     4441 gtataattgt aatgatagag tccttctttt gaatgacaat aacatatgta atttgaaaac
     4501 tttttcctac tttagcagat agctgctaca aagaatttta catataactc tctaaactat
     4561 cagtagtcca tgtgcattgg accttgatgt ctctcccatt ttgcagtag
//
