LOCUS       NM_001114402            3345 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus centlein (Cntln), mRNA.
ACCESSION   NM_001114402 XM_001070679
VERSION     NM_001114402.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3345)
  AUTHORS   Fang,G., Zhang,D., Yin,H., Zheng,L., Bi,X. and Yuan,L.
  TITLE     Centlein mediates an interaction between C-Nap1 and Cep68 to
            maintain centrosome cohesion
  JOURNAL   J Cell Sci 127 (Pt 8), 1631-1639 (2014)
   PUBMED   24554434
REFERENCE   2  (bases 1 to 3345)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 3345)
  AUTHORS   Makino,K., Umeda,K., Uezu,A., Hiragami,Y., Sakamoto,T., Ihn,H. and
            Nakanishi,H.
  TITLE     Identification and characterization of the novel centrosomal
            protein centlein
  JOURNAL   Biochem Biophys Res Commun 366 (4), 958-962 (2008)
   PUBMED   18086554
  REMARK    GeneRIF: The molecular characterization of a novel protein, named
            centlein (centrosomal protein), is described. Centlein was a
            protein of 721 amino acids with a calculated molecular weight of
            82,717 and possessed coiled-coil domains.[Centlein]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB369315.1, CB699924.1, BU759324.1, JAXUCZ010000005.1 and
            BF394214.1.
            
            On Feb 10, 2008 this sequence version replaced XM_001070679.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB369315.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-503               AB369315.1         1-503
            504-661             CB699924.1         141-298
            662-2164            AB369315.1         662-2164
            2165-2499           BU759324.1         18-352              c
            2500-2689           JAXUCZ010000005.1  104621657-104621846
            2690-3345           BF394214.1         1-656               c
FEATURES             Location/Qualifiers
     source          1..3345
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q31"
     gene            1..3345
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /note="centlein"
                     /db_xref="GeneID:679640"
                     /db_xref="RGD:1308101"
     CDS             1..2166
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /note="centrosomal protein; centlein, centrosomal protein"
                     /codon_start=1
                     /product="centlein"
                     /protein_id="NP_001107874.1"
                     /db_xref="GeneID:679640"
                     /db_xref="RGD:1308101"
                     /translation="MNLQDELDELKIYMTIDKTTIQELNRCMAEKREEQLFRHHEDAG
                     VKKSTPEKNEKAISEQTLEKVIELENRLKSFEKNSRKLKEESKKLKKENDFLKSHLQH
                     YQEDSESRGKELEKLLRVSSSVEQDKSELQTKVTALEREVTTLRRQVAKAKALRDENE
                     EVVNPEEKEHCPTDKAKSEMATTDVRAQHCDCKTTTTKVKFKAAKKKCSVGRHHTVLN
                     HSVKVMSHVENLSKDGWEDMSEGSSDSETQTFQNLGTVIVETSQNIRPIENDGNQKET
                     DQTEDSRAQQEVQTYSCEDLKAPQNTKKMTFQNKSGSLQKNLHSALPARVNREKCKTK
                     PAQKSSSNTILLRERIVSLQQQNSLLQNARKAAESSAKEFKEANEKLLHQQQISDHRF
                     QTSRQTIKLTLDLAELRKEKEDLLKKVESSSDITSLAEEVSRIMAPQIQVTTLGPSRS
                     TDLEIKQLQCKLKNATNELTKQSSSVKSLKLELLAKDDHMKAMQEKMSRMERDITMKR
                     HLIEDLKFRQKINSESNESFNEMLGTLEKKDLKMNLLISKLNDTETAMAQIKSAASEQ
                     LQGLALQSEQVLEGTQKKLLLANEKIEEFTVFVQALVNELQSDAHRTRQQVRELRQTQ
                     KSRHACKTSTHKAQTLAASILNISRSDLEEILHTGDEMEIEKTKIDAENDKDWMLYIQ
                     KLLQGQLPFASYLLEAVLGKIKENKKLTEGYFTVMKDIK"
     exon            1..100
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            101..192
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            193..725
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            726..900
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            901..976
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1200
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1389
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1487
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1614
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1800
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1986
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2064
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..3331
                     /gene="Cntln"
                     /gene_synonym="RGD1308101"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaatcttc aagatgaatt ggatgagctt aaaatatata tgactattga taaaacaaca
       61 atacaggaat tgaacagatg catggcagag aaaagagaag aacaactctt tagacaccat
      121 gaagatgctg gggtcaagaa gagtactcca gagaagaatg agaaagcaat atcggagcag
      181 acattagaga aggtcattga gttggaaaat cggctaaaat cttttgagaa aaactcaaga
      241 aaattaaaag aagagagtaa gaaattaaag aaagaaaatg atttcctgaa atcccactta
      301 caacactatc aagaagactc ggagagcaga ggaaaggagc tagagaaact actgagagtg
      361 agcagcagtg tagaacagga caaaagtgag cttcaaacaa aagtcactgc tctggagagg
      421 gaggtcacta cgctgaggag acaagtggca aaagctaagg ctttgagaga tgaaaacgaa
      481 gaggtggtga atccagagga aaaggaacac tgcccaacag acaaagctaa atctgagatg
      541 gccaccacag atgtgagagc ccagcactgt gactgcaaga caaccactac caaggtgaaa
      601 tttaaagctg ccaagaaaaa gtgctctgtg ggtcgccacc acactgttct caatcactcc
      661 gtcaaggtta tgagccatgt ggagaacctc agcaaggatg gctgggagga catgagtgaa
      721 ggcagcagtg attctgaaac acaaaccttt caaaatttgg gaacagttat tgtggaaaca
      781 tcccagaata taaggcctat agaaaatgat ggaaaccaga aggaaactga ccaaacagaa
      841 gacagccgtg ctcaacaaga agtgcagaca tactcctgtg aggacctcaa ggccccacag
      901 aatacgaaga aaatgacttt tcaaaacaag agtggaagtc tacagaagaa cttacacagt
      961 gcccttcctg ccagagttaa cagagaaaag tgcaaaacta aacctgccca gaaatccagt
     1021 agcaacacta ttttattacg agaacggatt gtatccttgc agcaacaaaa cagtttgctt
     1081 cagaatgcca ggaaagcagc agagtcgtct gctaaagaat ttaaagaagc aaatgaaaaa
     1141 ctcctccatc aacagcagat atctgatcac cgattccaga ccagcaggca gacaataaag
     1201 ctaactcttg atttagctga acttcgaaaa gagaaagaag atttgttgaa gaaagtggag
     1261 tcttcatctg acatcacaag cttggcagaa gaagtttcca gaataatggc cccacagata
     1321 caagttacca cactgggtcc ttcaaggagc acggatttgg aaataaagca attgcagtgt
     1381 aaactaaaga atgcaactaa cgaactcact aagcagtcct cgagtgtgaa gtcgctgaag
     1441 ctggaacttc tggcgaagga tgaccacatg aaggcgatgc aggagaagat gtctcgaatg
     1501 gagagagata taaccatgaa aagacacctg attgaggact tgaaatttcg acagaaaata
     1561 aattcagaaa gtaatgagag ttttaatgaa atgttaggaa ctcttgaaaa aaaggatctc
     1621 aagatgaatc tcctgatatc aaaactaaat gacacggaga cagccatggc tcagatcaag
     1681 agcgcagcgt cggagcagct ccaaggcttg gcgttgcaga gtgagcaggt cctggaaggc
     1741 acgcagaaga aactgctgct ggccaatgaa aagatcgagg agttcactgt ctttgtgcag
     1801 gctttggtca atgagttaca aagtgatgcc cataggacaa gacaacaagt cagagagctt
     1861 aggcagacgc agaaaagcag acatgcttgt aaaacctcaa cccataaagc ccagaccttg
     1921 gccgcttcca tcctgaacat ctcacggtca gacctagaag aaatattgca cacaggagat
     1981 gaaatggaaa tcgagaagac aaagatagat gctgaaaatg acaaggactg gatgttgtac
     2041 attcagaaac ttctccaagg acagcttcct tttgcatcat atttactaga agcagtgctg
     2101 gggaaaataa aggaaaacaa gaagctgact gaaggatatt tcacagtcat gaaagacatt
     2161 aaataaagtt gcagcagacc tgttttcaaa tgcaggaact tggtgtgctg cagtggtgaa
     2221 cagtgcagat gctgtaaaca gtcactgctt cagcaagcag cgggcagctt ctacccagca
     2281 aaggctgctg agactgaccg ctgaaccgat gaagctaacc aagtgctcgg cctcgccaaa
     2341 gggaagtcta gcatttgaat gctggctgtt atccccaatc aatgcaaact taaaatggtt
     2401 tccttccagt gcttaagaaa acaaaacaag cttctcacag gcaaatgggc ctgagtataa
     2461 aatgaaaaag ttataaataa aggacttaat ataaactcat atgaaaacta gattttttat
     2521 ataaaactat tataaatgag atccagtgaa caacatcttt acatggtgag aaagtatgaa
     2581 gtgaattatc ctaatgtgaa ggaggagcac tgagtgaagc caattgtata gctccattgt
     2641 aactattctc attgacacac tggattatac gggacatact ctgtttttct agaactctct
     2701 ggataaacaa gaaccttttc ctcctctgtc tgcttgtgct gctgtataaa tcagcaaaga
     2761 ccagaacccc agtgtgtaat gttgctctag acctagcaga gctcctacca cggccatcta
     2821 attaacaatg ccttctcact gtgatgggag cattgtatgt gattgttacc accccctccc
     2881 tgcacgtcct cactgagttc ttgccacaca ttcttggagc ctctgagtca ctgaacttgg
     2941 cctctatgtt tgctgttggg gccatctttg cagaatactt tgtaactgta ggtatgcctg
     3001 tcttcttatt acccaggctc actttatcag tcctgtcata gcgtatttct gaaaatctta
     3061 ctgttaacct gaaatcatct gtttttaata tgctcactct tcgttttatg gttcatcctt
     3121 atttcctcct ttaaaatgta gatcccatga gattaaggta ggtgttggca aattgaggcc
     3181 catagccaaa tctagcctgc cacctacttt atagagttca cagactaaac atttttctat
     3241 tttattaaac tgtttaaaaa caatactttg tagcatgtaa aaatcatatg aaattcaatt
     3301 ttaatgtctt atcaataaag atttattgag aaaaaaaaaa aaaaa
//
