LOCUS       NM_001077585            1028 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus canopy FGF signaling regulator 2 (Cnpy2), mRNA.
ACCESSION   NM_001077585 XM_001065386
VERSION     NM_001077585.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Do HT, Tselykh TV, Makela J, Ho TH, Olkkonen VM, Bornhauser BC,
            Korhonen L, Zelcer N and Lindholm D.
  TITLE     Fibroblast growth factor-21 (FGF21) regulates low-density
            lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin
            ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting
            saposin-like protein (Msap)
  JOURNAL   J Biol Chem 287 (16), 12602-12611 (2012)
   PUBMED   22378787
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC126101.1.
            
            On Nov 9, 2006 this sequence version replaced XM_001065386.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC126101.1, FQ220178.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1028
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /note="canopy FGF signaling regulator 2"
                     /db_xref="GeneID:685814"
                     /db_xref="RGD:1589072"
     exon            1..295
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
     exon            296..408
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..869
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /note="transmembrane protein 4; protein canopy homolog 2;
                     canopy 2 homolog"
                     /codon_start=1
                     /product="protein canopy homolog 2 precursor"
                     /protein_id="NP_001071053.1"
                     /db_xref="GeneID:685814"
                     /db_xref="RGD:1589072"
                     /translation="MKGWGWLALLLGVLLGTTWARRSQDLHCGACRALVDELEWEIAR
                     VDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHR
                     KNYVRVVGRNGGSSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVK
                     DKLCSKRTDLCDHALHRSHDEL"
     exon            409..524
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
     exon            525..728
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
     exon            729..825
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
     exon            826..999
                     /gene="Cnpy2"
                     /gene_synonym="Tmem4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcctcggag gcgcccctaa agctgcctgc tcgcgcgaga gtttggaggg gctggcttag
       61 ggtcattttc gtggaggctc gcacgggacc ttcagatctc cgcttaggtt cctggttagg
      121 tacggggtgc tgggccaggc ggtcactggc caccctgaac ctggcgagcg ccggagcgct
      181 ctggagaagc ccggacagcc ccgttctttc cagccagctg ctagggttgg gagccaaagt
      241 gagagtccgg ctgctttcca gtgcctgggc cacggcggcg gccgtgggag cagaggtgga
      301 gcgaccctgt cccgctaaag atgaaaggct ggggttggct ggccctactt ttgggggtcc
      361 tgctgggaac tacctgggct cgaaggagcc aggatctaca ctgtggagct tgcagggctc
      421 tggtggatga attagagtgg gaaattgccc gcgtggaccc caagaagacc attcagatgg
      481 gatccttccg aatcaatcca gatggcagcc agtcagttgt ggaggttcct tatgcccgct
      541 cagaggccca cctcacggag ttgcttgagg agatatgtga ccgaatgaag gagtatgggg
      601 aacagattga cccttctacc caccgcaaga actacgtccg tgttgtcggc cggaacggag
      661 gatccagtga actagactta cagggtatcc gaatcgattc agatatcagt ggcaccctca
      721 agtttgcgtg tgagagcatt gtggaggagt acgaggatga acttattgaa ttcttttcaa
      781 gagaggctga caacgttaaa gacaaacttt gcagtaagcg gacagatcta tgtgaccatg
      841 ccctgcacag atctcatgat gagctatgac tcacaggagc aagcagccca caccagcttg
      901 gtgaaacacc cccgggaggg gaaggaagat ggcggcattg ccttttatat tatgttttta
      961 tggaaatgaa ctgaaaaaaa actcttgaaa ccaaaagtaa aaaaaaaaaa aaaaaaaaaa
     1021 aaaaaaaa
//
