LOCUS       NM_001107313            2614 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus CCR4-NOT transcription complex, subunit 7
            (Cnot7), mRNA.
ACCESSION   NM_001107313 XM_001058225 XM_001058352 XM_001058414 XM_001058476
            XM_224894
VERSION     NM_001107313.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2614)
  AUTHORS   Shi JX, Li JS, Hu R, Shi Y, Su X, Li Q and Zhang F.
  TITLE     CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by
            tristetraprolin
  JOURNAL   Cell Signal 26 (11), 2390-2396 (2014)
   PUBMED   25038453
REFERENCE   2  (bases 1 to 2614)
  AUTHORS   Wahle E and Winkler GS.
  TITLE     RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3
            complexes
  JOURNAL   Biochim Biophys Acta 1829 (6-7), 561-570 (2013)
   PUBMED   23337855
REFERENCE   3  (bases 1 to 2614)
  AUTHORS   Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P,
            Chettab K, Sentis S and Corbo L.
  TITLE     hCAF1/CNOT7 regulates interferon signalling by targeting STAT1
  JOURNAL   EMBO J 32 (5), 688-700 (2013)
   PUBMED   23386060
REFERENCE   4  (bases 1 to 2614)
  AUTHORS   Cai LY, Kato T, Chen M, Wang H, Sekine E, Izumi S and Kato Y.
  TITLE     Accumulated HSV1-TK proteins interfere with spermatogenesis through
            a disruption of the integrity of Sertoli-germ cell junctions
  JOURNAL   J Reprod Dev 58 (5), 544-551 (2012)
   PUBMED   22785219
REFERENCE   5  (bases 1 to 2614)
  AUTHORS   Hosoda N, Funakoshi Y, Hirasawa M, Yamagishi R, Asano Y, Miyagawa
            R, Ogami K, Tsujimoto M and Hoshino S.
  TITLE     Anti-proliferative protein Tob negatively regulates CPEB3 target by
            recruiting Caf1 deadenylase
  JOURNAL   EMBO J 30 (7), 1311-1323 (2011)
   PUBMED   21336257
REFERENCE   6  (bases 1 to 2614)
  AUTHORS   Horiuchi M, Takeuchi K, Noda N, Muroya N, Suzuki T, Nakamura T,
            Kawamura-Tsuzuku J, Takahasi K, Yamamoto T and Inagaki F.
  TITLE     Structural basis for the antiproliferative activity of the
            Tob-hCaf1 complex
  JOURNAL   J Biol Chem 284 (19), 13244-13255 (2009)
   PUBMED   19276069
REFERENCE   7  (bases 1 to 2614)
  AUTHORS   Zheng D, Ezzeddine N, Chen CY, Zhu W, He X and Shyu AB.
  TITLE     Deadenylation is prerequisite for P-body formation and mRNA decay
            in mammalian cells
  JOURNAL   J Cell Biol 182 (1), 89-101 (2008)
   PUBMED   18625844
REFERENCE   8  (bases 1 to 2614)
  AUTHORS   Bianchin C, Mauxion F, Sentis S, Seraphin B and Corbo L.
  TITLE     Conservation of the deadenylase activity of proteins of the Caf1
            family in human
  JOURNAL   RNA 11 (4), 487-494 (2005)
   PUBMED   15769875
REFERENCE   9  (bases 1 to 2614)
  AUTHORS   Bogdan JA, Adams-Burton C, Pedicord DL, Sukovich DA, Benfield PA,
            Corjay MH, Stoltenborg JK and Dicker IB.
  TITLE     Human carbon catabolite repressor protein (CCR4)-associative factor
            1: cloning, expression and characterization of its interaction with
            the B-cell translocation protein BTG1
  JOURNAL   Biochem J 336 (Pt 2) (Pt 2), 471-481 (1998)
   PUBMED   9820826
REFERENCE   10 (bases 1 to 2614)
  AUTHORS   Draper MP, Salvadore C and Denis CL.
  TITLE     Identification of a mouse protein whose homolog in Saccharomyces
            cerevisiae is a component of the CCR4 transcriptional regulatory
            complex
  JOURNAL   Mol Cell Biol 15 (7), 3487-3495 (1995)
   PUBMED   7791755
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473995.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224894.4, XM_001058414.1, XM_001058476.1, XM_001058352.1,
            XM_001058225.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167766.1, SRR8487227.65766.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2614
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.1"
     gene            1..2614
                     /gene="Cnot7"
                     /note="CCR4-NOT transcription complex, subunit 7"
                     /db_xref="GeneID:306492"
                     /db_xref="RGD:1305313"
     exon            1..203
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     exon            204..415
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..1156
                     /gene="Cnot7"
                     /EC_number="3.1.13.4"
                     /codon_start=1
                     /product="CCR4-NOT transcription complex subunit 7"
                     /protein_id="NP_001100783.1"
                     /db_xref="GeneID:306492"
                     /db_xref="RGD:1305313"
                     /translation="MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFP
                     GVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFN
                     LTEDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGY
                     DFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLEL
                     ERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNA
                     YEEEASKQS"
     exon            416..609
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     exon            610..771
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     exon            772..916
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1027
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..2614
                     /gene="Cnot7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcatgccgcg ccctcgatag gacgtgcgag gagcgacgtc gcagcgctgg gcagagcgca
       61 gctccggctc ccctttcccc tttgcagggc gagagctgtc tatggggctc cctctgccgc
      121 cgccggtacc gccaccgcca ccgccgccgg gtgctatctc tatggcgagg aggaggagga
      181 ggagcgcgag ctcagagaca caagtacaca agtaaagagt aaagtatttt tatgaaacaa
      241 atcttcaatc aagtataaca ttttgatgct tcgcatctag actccttgtg ctgtcactat
      301 gccagcagca actgtagatc atagccaaag aatttgtgaa gtttgggctt gtaacctgga
      361 tgaagagatg aagaaaatcc gtcaagttat ccgaaaatat aattatgttg ctatggacac
      421 cgagtttcca ggcgttgttg caaggcccat tggagaattc agaagcaatg ctgactatca
      481 gtaccaactg ttgcgatgta atgtagactt gttaaagata attcagcttg gactgacatt
      541 tatgaatgag caaggagaat accctccagg aacatcaact tggcagttta attttaaatt
      601 taatttgacg gaggacatgt atgctcagga ctctatagag ctactgacaa cgtctggcat
      661 ccagtttaaa aaacatgagg aggaagggat tgagacccag tattttgcag aacttcttat
      721 gacctcagga gtggttctct gtgaaggggt caaatggtta tcatttcata gtggttatga
      781 ctttggctat ttaatcaaaa ttctgaccaa ctctaacttg cctgaagaag agcttgattt
      841 ctttgagatc cttcgattat tcttccctgt catctatgat gtgaagtacc tcatgaagag
      901 ctgcaagaac ctcaagggtg gactgcagga agttgctgag cagttagagc tggagcggat
      961 aggacctcaa caccaggcag gatctgactc actgcttaca ggaatggcct ttttcaaaat
     1021 gagagaaatg ttctttgaag atcacattga tgatgccaaa tactgtggcc acttatacgg
     1081 ccttggttct ggctcatcct atgtacagaa cggcacaggg aatgcatatg aagaggaagc
     1141 cagcaagcag tcgtgacagg aaatagtctt cttattttta ttttatacga gttacacaca
     1201 tgcttgtata taggttttat catcccttaa ataataggca atacctgccc ctcctttggt
     1261 agcccttctt ttctgctttc agtaataagt atggcctttc ttagctatga tcttaataaa
     1321 ttaaagtaca ttcaggttaa atctggcctt aatttaatac acctcttatc aagcttgtgt
     1381 gacaaagcta cattactgaa taatttgaca aactttgcct acttgagctt ggttttgttt
     1441 ttccctttcc taaattaact agcattgact gtaatttatt tccctcttcc gtgcctctcc
     1501 tcctattctg cagtacttat aggtatttaa gattgtggac catcaagttt gcactttata
     1561 gagtgatttc aatcctctat tttatcagaa attgtgattt ttcttgctct tagctagaaa
     1621 aatgaccatc caccaccttt ttacagtatt tgcttgtttt tgacattcag agtacagcac
     1681 gtgcattgtg caaattgttg attcaacggg actaacaaga agacaaggaa ctactgaaga
     1741 gcctagtaac tactgtttct gtgtgtagtg tttaaccttc cgaacacatc tcctgtctgt
     1801 tggtttctaa ttggcatgca taggctgcta tgtgactgaa gaatttcaaa ccagctttac
     1861 acccttcagg aagaagccct tgcgattgga ggtttccact ctgccagaaa gaaactggcg
     1921 tttaagatgt ggaactacag ttttatgaca gcaacgcttc ccttgaccgg cttcctttta
     1981 ctccatcact tttaccctta atgttttatt ttataaacat atttatgatg ttcttgattt
     2041 gttgactacg caaatcaatt tcattaaagt ccaaagataa caagtcttta ggtacatttt
     2101 atatcaaatt aaaaatacaa aaaaaaatgt gatttcataa atgctacaaa aataaataat
     2161 ggagagattt ggtgcaaaac aacaaaatgc aaaatatata tataaataca cacatatagc
     2221 taataaaatt acctgaggag tgtaatgctt gtttattttt ttgtgtatat ctttgcaatc
     2281 tattttatat atattgacaa gagactgtga aatatttagc catgcagaat acgtgaccac
     2341 accagagcat gtgttggaag attttggtga acattaactc taccctgaag tgacggacta
     2401 caagttgtaa tgtgtgttat ctacacttca atcaataata ttagaaagtc tccaactgtt
     2461 agcaacacag ttcatttccc ttgtacattc tgtatacatg atacgaaaat gctgtacctg
     2521 ggcggtcctt tttaaactaa acattatttg caaaacagag ggtattattt gtttttaaag
     2581 cttttgtaaa taaaggcttc aagaatgttt tcct
//
