LOCUS       XM_017596510            4762 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus cyclin and CBS domain divalent metal
            cation transport mediator 4 (Cnnm4), transcript variant X1, mRNA.
ACCESSION   XM_017596510
VERSION     XM_017596510.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051344.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017596510.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017596510.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4762
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4762
                     /gene="Cnnm4"
                     /note="cyclin and CBS domain divalent metal cation
                     transport mediator 4; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 20 ESTs, 14 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 37 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:363216"
                     /db_xref="RGD:1305571"
     CDS             102..2483
                     /gene="Cnnm4"
                     /codon_start=1
                     /product="metal transporter CNNM4 isoform X1"
                     /protein_id="XP_017451999.1"
                     /db_xref="GeneID:363216"
                     /db_xref="RGD:1305571"
                     /translation="MAPGGGGGRRDGWPARGRLLLAALLLLLWTRAASGQSSPQQSVI
                     LGMRLASCNKSCGMNPDGIIFVSEGSTVNLRLYGHRLGEISSNLISFTEVDDAETVHN
                     STNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALCTRTRADGPWLK
                     WTDKDSLLFMVEEHGRFLPLWLHILLVLVLLVLSGIFSGLNLGLMALDPMELRIVQNC
                     GTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIG
                     IVIFGEILPQALCSRHGLAVGANTIVLTKIFMLLTFPLSFPISKLLDFVLGQEIRTVY
                     NREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDF
                     NTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFV
                     FHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILD
                     ESDTYTDNRTRKRVSMKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVPQFSPS
                     LMSEKILLRLLKYPDVIQELRFDEHNKHCTRHYLYTRNKPADCFILILQGKVEVEAGK
                     ENMKFETGAFSYYGTMALSLAPPAPPVQAGCSTGKLNSLLSRLADRSPAHPTPLSRSA
                     SLSYPDRNTDMTPSSLAGSNQFGSCILGQYVSDFSVRALTDLQYIKVTRQQYQNGLLA
                     SRMDNSPQLTLDGCATCTENLSERPELPVVDETTTLLNERNLLLHRASQEGTI"
ORIGIN      
        1 ggggcagttg gcgcggcggc ggcggagcgg caggagggca ggagcggcgg cgccgagtga
       61 ggcgcgcggc ggggcgcggg cagcggcggg gccggagcaa catggcgccg gggggcgggg
      121 gcgggcggcg ggacggctgg ccggcccgag ggcgcctcct cctggccgcg ctgctgctgc
      181 tgctatggac gcgggcggcc agcggccaga gcagccccca gcagagcgtg atcctaggca
      241 tgaggctggc gagctgcaac aagtcgtgcg ggatgaaccc ggatggcatc atcttcgtgt
      301 ccgagggcag cacggtgaac ttgaggctct acggccacag actgggcgag atctctagca
      361 acctgatctc cttcaccgag gtggacgacg ccgagacggt ccacaactcc accaactgcc
      421 tggagctcac caaggactta gtggtccagc ggctggtcaa cgtgagccgc gggaacacgt
      481 cggggatgct agtggtgatt accaagttcc tgcggaggag tgagaacatg aagctgtacg
      541 cgctgtgcac ccggacccgg gccgacgggc cctggctcaa atggacggac aaggactccc
      601 tgctcttcat ggtggaggag catgggaggt ttctgccgct ctggctgcac atccttcttg
      661 ttttggtgct gttggtgctg tcgggcatct tttctggcct caacttgggg cttatggccc
      721 tggacccgat ggagttgcgc atcgtgcaga actgtggaac tgagaaggag agaaggtacg
      781 ctcgcaagat agagcccatc aggcgcaagg gcaactacct gctctgctcg ctgctcctgg
      841 ggaatgtgct agtcaacacc tccctcacca tccttctaga caacctcatc ggttctggca
      901 tcatggcagt ggcctcctcc accattggca ttgtcatctt tggggagatc ttacctcaag
      961 ccctgtgctc caggcatggg ctggctgtgg gtgccaacac tattgttctc accaaaatct
     1021 ttatgttact cactttcccc ctgagtttcc ccattagcaa actcctggac ttcgtcttgg
     1081 gtcaggagat tcgcactgtt tacaatcggg agaaactgat ggagatgttg aaggtgacag
     1141 agccctataa tgacctggtg aaggaggagt taaacatgat ccagggtgct ctggaactaa
     1201 ggaccaaaac tgtggaggat atcatgaccc agctacacga ctgcttcatg atccgcagtg
     1261 atgccattct ggacttcaac accatgtcgg agattatgga gagtggctat actcgcattc
     1321 ctgtgtttga agatgagcag tccaatatcg tagatatcct ttacgtcaaa gacctggctt
     1381 ttgttgaccc agatgactgc accccgctca agacgatcac tcgcttctac aaccacccgg
     1441 tccattttgt ttttcatgac accaagctgg atgccatgct ggaggaattc aagaagggca
     1501 agtcccacct ggccatcgtg cagaaggtga acaatgaggg cgagggcgac cccttctacg
     1561 aggtgctggg cctggtcacc ctggaggacg tcatcgagga gatcatcaag tctgagatcc
     1621 tggatgagtc ggacacgtac actgacaatc gaacccggaa acgggtgtcc atgaagaaca
     1681 agcgtgactt ctctgccttc aaggatgctg acaatgaact caaagtgaaa atctcacctc
     1741 agcttcttct ggccgctcac cgcttcctgg ccacagaggt gccgcagttc agtccctccc
     1801 tgatgtcaga gaagatcctg ctccggctgc tcaagtaccc tgacgtcatt caggagctca
     1861 ggttcgacga gcacaacaag cactgcaccc gccactacct gtacacccgg aacaagccag
     1921 ccgactgctt cattctcatc ctgcagggga aggtggaggt ggaagcaggc aaggagaaca
     1981 tgaagtttga gaccggtgcc ttctcgtact atgggaccat ggctctgtcc ctggcgcccc
     2041 cagcgcctcc tgtgcaggct gggtgctcaa caggcaaact gaactccctg ctctcccggc
     2101 tcgcagaccg gtccccagcc cacccaactc cactcagccg ttcagcctcc ctcagttacc
     2161 cggaccgcaa cacagacatg acaccctcct ccctggcagg cagcaaccag tttggcagct
     2221 gcattctggg ccagtatgtc tctgacttca gtgtgcgggc gctcacagac ctgcagtaca
     2281 ttaaggtcac aagacagcag taccagaacg ggctgctggc ctcccgcatg gacaacagcc
     2341 cccagctcac cttggatggc tgtgccacct gcacagagaa cttatccgag aggcctgagc
     2401 tgcccgtggt ggacgagacg acgactcttc tcaatgaacg caacttgttg ctgcacagag
     2461 cctcccaaga gggcaccatc tgacaggagg gcccggggac tcccgcccac cctgcggggt
     2521 ctccccagtg ggcccacatg aagtcaggga gcctattagg ctagaagggg tgcaggtaga
     2581 tatcctgcat gactgagcaa ccagacgtcc ctgcccaggg gctctggctg cagatgggga
     2641 cctctgaaca gctctgacgt gaaacctacc cagtccagct agtgagcaaa ggctgtgggg
     2701 ttttgttttt taaaacactg agagaagttt taagctaggc gcattgctcc tctttttaaa
     2761 tatcattttg ggaagggaag acagggttaa ggaactttat gtaaaaaaac aaaatttttt
     2821 ttcaagaagc cccacaaact gtaaaagggg aggagggctc ctcactccag gaagcaatag
     2881 ccataacctg tttccagcag agaccttgca gcctgtgcct gttgctccag gaggcgctct
     2941 tctgcagcag tgggggcctg gagcccactg gaggggattc ctgggaggaa gcagggatcc
     3001 aggtcataac atcgactgcc gggacacacg agcagaagtc atagagaagt gctgggcaac
     3061 ggatcaggga cacggtgacc ccagcatcag agagggatac atctgctctt atcaactgcc
     3121 ggatccagtg atctcctaga accctgccca gggcctctct tggtgaggcg ggactcggcc
     3181 gagaaccaga cctggctctc atctacctac cactttggac agttctcccc tggaagggtc
     3241 tggccccaag agttaggcgt ggtctttggc tctgcagttg cttatctgct tcctggctct
     3301 ggtttcactc ttaccaaagg tttcctctca gaggggagag catcaacatt agaggtgact
     3361 tattgggcac tcctggtagt ctcaggctat ctgataatag gtagatctgt gtcagcagtc
     3421 attcctaccc aaccacctgc tggaagagtc agggctcagt agtccgccca ggaaggtctc
     3481 tttcctgact ccccattctt atctatcctg gtccttctgg ggactggaag ccccccaagc
     3541 tcagtcattg tgtccttgcc tgtgtagtgg gcagaggacc acctgagctc tgagctcttt
     3601 tccacttaag gaccccaaga aaggagggtt ccctaaggac aagcagcaga tggcctggtt
     3661 ctctctgcct gaggcctgtg ctggtgagag gtatttgatg agcataggct gaagctcttg
     3721 gtactgcagg gcaatccaca ccatgtgaaa tcctacccca gttccacctg ggaaacctga
     3781 gtgcaatcag tccatgggac tgagctgcac acttctattg tagggagact gtatgaccaa
     3841 gggccacatc taccttttgt tgggacaaat ggagctgcag tataagagcc aggccagcgg
     3901 gagcacgggc gagtgggagc acaggccatc tgtgtttgtt cacttcattc ctcagccagc
     3961 ggagtcctgt cacaccaggt actctgctgt ctgtgtaccc agagaatcct aactcctagg
     4021 atgatgcacc aaggtgtcct gtacccctgg ccaatctgaa gtctcctcca ctcacaaaat
     4081 ttactctgag aagcctggag atggcggctt tcaacgataa gggaaaaaga catcagacct
     4141 ctcgttcctt aagaaactct tagttctctg taggtgcggc atgctcctga gtctgtagat
     4201 gaggtgccta gctgtgttac tgtgagacct aagtgccagg tagagcaaaa ccctgtggtg
     4261 ggtgtgaggc aaacgtagca ggtgcacaca cttccacagc tacctctctg catacacagt
     4321 caccgacagc cgggccccgc ccctcccctc ctcacttaga atcacttctt gcagagggtc
     4381 ataattattt ccaaatatta ctgttctgat gacttcctcc tcctagtgca atttttcact
     4441 tcttccaacc tctggttcct gggcagagcc ataccctgga actggcctgg tctgcgtgtc
     4501 ttcccagcag gggaggactc cacagacggc gtccaagtgg gtaggcaagt cacagccgcc
     4561 atagcagatg actcctattt attttgcatt aagattttaa tttgtatatt tttgtgattt
     4621 attttggcat tgttatgagt ttgactctcg gggagttttg ttgttatgac tcttgtgtct
     4681 tttgtcacaa aacaatgata atatttgcta aacaatatat ggaatttatt tttgattggt
     4741 aataaaaaat gaaatgcaca ta
//
