LOCUS       NM_001401623            5189 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cyclin and CBS domain divalent metal cation
            transport mediator 1 (Cnnm1), transcript variant 2, mRNA.
ACCESSION   NM_001401623 XM_006231483
VERSION     NM_001401623.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5189)
  AUTHORS   Guo,D., Ling,J., Wang,M.H., She,J.X., Gu,J. and Wang,C.Y.
  TITLE     Physical interaction and functional coupling between ACDP4 and the
            intracellular ion chaperone COX11, an implication of the role of
            ACDP4 in essential metal ion transport and homeostasis
  JOURNAL   Mol Pain 1, 15 (2005)
   PUBMED   15840172
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5189)
  AUTHORS   Wang,C.Y., Yang,P., Shi,J.D., Purohit,S., Guo,D., An,H., Gu,J.G.,
            Ling,J., Dong,Z. and She,J.X.
  TITLE     Molecular cloning and characterization of the mouse Acdp gene
            family
  JOURNAL   BMC Genomics 5 (1), 7 (2004)
   PUBMED   14723793
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 16, 2022 this sequence version replaced XM_006231483.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.8079.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1712              JAXUCZ010000001.1  252245623-252247334
            1713-1856           JAXUCZ010000001.1  252270351-252270494
            1857-1997           JAXUCZ010000001.1  252273453-252273593
            1998-2167           JAXUCZ010000001.1  252276247-252276416
            2168-2267           JAXUCZ010000001.1  252278434-252278533
            2268-2315           JAXUCZ010000001.1  252278983-252279030
            2316-2378           JAXUCZ010000001.1  252282779-252282841
            2379-2536           JAXUCZ010000001.1  252290651-252290808
            2537-2720           JAXUCZ010000001.1  252298555-252298738
            2721-2870           JAXUCZ010000001.1  252298859-252299008
            2871-2972           JAXUCZ010000001.1  252300683-252300784
            2973-5189           JAXUCZ010000001.1  252301989-252304205
FEATURES             Location/Qualifiers
     source          1..5189
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..5189
                     /gene="Cnnm1"
                     /note="cyclin and CBS domain divalent metal cation
                     transport mediator 1"
                     /db_xref="GeneID:309387"
                     /db_xref="RGD:1308728"
     exon            1..1712
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..3052
                     /gene="Cnnm1"
                     /note="isoform 2 is encoded by transcript variant 2; metal
                     transporter CNNM1; cyclin M1"
                     /codon_start=1
                     /product="metal transporter CNNM1 isoform 2"
                     /protein_id="NP_001388552.1"
                     /db_xref="GeneID:309387"
                     /db_xref="RGD:1308728"
                     /translation="MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLG
                     LRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPAVPAAPVPAPSLAPGENGTGDW
                     APRLVFIEEPPGAGSAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALV
                     QVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDL
                     LPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVR
                     GRGTHLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGA
                     VFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFY
                     TREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDF
                     ATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHC
                     VFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEIL
                     DETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPF
                     KSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRSRPVDYFVLLLQGKVEVE
                     VGKEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLPVSVSRTFAFSRGD
                     SLAGSPVNRSPSRCSGLNRSESPNRERSDFGGSNTQLCSNNLYTPDYSVHILSDVQFV
                     KITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNR
                     TSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHKAQQVSLSPVTVPTAAASET
                     ECCNIHLDPEASPCSSDSEETMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT"
     exon            1713..1856
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..1997
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2167
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2267
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..2315
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2316..2378
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2379..2536
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2720
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2870
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..2972
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
     exon            2973..5189
                     /gene="Cnnm1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcctccagc ccacgcgcgc aaggggagca cacgtggtga cctgcctggg gccggattcc
       61 gggctccagc tcctcctccc tcccctccag ctcgcgctcg gcttgctgca gtatcacgtg
      121 caaccgcgcc gggtgcagga tggcggcggc ggccgcggcg gcagcagcgc tgggtgtcag
      181 gctccgggac tgctgcagcc ggggcgccgt actactcctc ttcttctccc tgtcccctcg
      241 gcccccggcc gccgctgcct ggctgctagg tctgagacct gaagacactg ccggaggccg
      301 cgtgtcgctg gaggggggca ccctgcgggc ggccgaaggc accagcttcc tcttgcgggt
      361 ctacttccag cctgggccgg cggtccccgc cgcgcccgtg cccgcaccct ccctggcccc
      421 gggggagaat ggcacgggcg attgggcccc gcggctcgta ttcatcgagg agcccccggg
      481 cgccggcagc gcggcgccca gcgcggtccc cactcgtccc ccgggaccgc agcgctgtcg
      541 cgagcagagc gactgggcgt cggacgtgga ggtcctgggg cccctgcgcc ccgggggcgt
      601 ggcgggctcg gccctggtcc aggtgcgggt gcgggagctg cggaagggcg aggcggagcg
      661 cggcggcgcg ggcggcggcg ggaagctctt ttcgctgtgc gcctgggacg ggcgcgcttg
      721 gcaccaccac ggcgcagccg gcggcttcct gctgcgcgtc cgcccgcgcc tctacggccc
      781 gggtggggac ctgctgccgc ccgcgtggct gcgagcgctc ggggcgctcc tgctgttggc
      841 cctgtccgcc ctgttcagcg gcctgcgcct gagcctgctc tcgctggacc cggtggagtt
      901 acgggtgctg cggaacagtg gctcggccgc cgagcaggag caggcgcgcc gcgtgcaggc
      961 cgtacgcggc agggggaccc atctgctctg caccctgctc ctgggccaag ccggcgccaa
     1021 tgccgcgctg gccggctggc tgtacgcctc gctgccaccg ggcgtcgggg accccgggga
     1081 ggactccggc gaggcggggg ttcatttccc gtggctgccg gcgctcgtgt gcaccggcgc
     1141 cgtgttcctg ggagccgaga tctgtccgta ctccgtgtgc tcacgccacg ggctggccat
     1201 cgcctctcac agtgtgtgcc taacccggct cctcatggcg gccgccttcc cggtgtgcta
     1261 cccgctgggc cgcctcctgg actgggctct gcgccaggag atcagcacct tctacacgag
     1321 ggagaagctg ctggagacgc tgagggccgc cgatccttac agcgacctgg tgaaggaaga
     1381 gctcaacatc atccagggcg ccctggagct gcgcaccaag gtggtagagg aggtgctgac
     1441 ccctctcggg gactgcttca tgctgcgctc cgacgctgtg cttgacttcg ccactgtatc
     1501 cgagatcctc cgtagtggct acactcgcat cccggtgtac gagggcgacc agaggcacaa
     1561 cattgtggac attctgttcg tcaaagactt ggcctttgtg gacccggacg actgtacccc
     1621 cctgctcaca gtcacccgct tctacaacag gcccctgcat tgcgtcttca atgatacccg
     1681 gctggacaca gtactggagg agtttaagaa gggaaaatca cacctggcca ttgtccagag
     1741 agtgaacaac gagggtgaag gagacccttt ctatgaggtg atgggcatcg tcacactgga
     1801 ggacatcata gaagagatca tcaagtcgga gatcctagat gaaactgacc tctacactga
     1861 caatcggaaa aagcagaggg tcccacaccg ggagaggagg cggcatgatt tctctctgtt
     1921 caagctttca gactcagaga tcagagtcaa gatctcgcca cagctcttgc tcgccacaca
     1981 tcgcttcatg gccacagaag tggagccctt taagtctctc tacctttccg agaagatcct
     2041 gctccggctt ctgaaacatc ccaacgtgat ccaggagctt aagtttgatg agaggaacaa
     2101 gaaagcccca gaacactacc tctaccagcg cagccgcccc gtggactatt ttgtgctgct
     2161 tttacagggg aaagtggaag tggaggtcgg taaggaaggc cttcgttttg agaatggagc
     2221 ctttacctac tacggtgtcc cagccatcat gaccagcgcc tgctcagata acgacgtgcg
     2281 gaaggttgga agtctggctg gatcctctgt cttcctgccc gtctctgtgt ctcgtacctt
     2341 cgccttcagc agaggggact ctctggcagg ctccccagta aaccggtccc cttctcgctg
     2401 cagcgggttg aatcgttccg agtctccaaa ccgagagcgc agtgacttcg gcgggagcaa
     2461 cacgcagctg tgcagcaaca acctctacac acccgactac tctgtgcaca tcctcagcga
     2521 tgtgcagttt gtgaagatca cacggcaaca gtaccagaac gcactcacgg cctgccacat
     2581 ggacagctcg ccccagtccc cagatatgga ggccttcacc gacggcgact ccaccaaggc
     2641 ccccaccact cgaggcacac ctcagactcc aaaggacgac ccggtcctca cactcctgag
     2701 taacaggacc agcttgccat gcagccgctc agatggtctg agaagcccgg gcgaggtggt
     2761 gtacctgagg atggaggaga tggccttccc ccaggaagag atgcccaact ttgaggagca
     2821 caaggcacag caagtctcgc tgtcccctgt gactgttcct acagcagcag cttcagagac
     2881 tgaatgctgt aatatccacc tggacccaga ggccagcccc tgcagcagtg actctgagga
     2941 aaccatgggc aagaagctgc taaggacctt gagtggccgg aagagaaaga aatcagcaga
     3001 cggagagaga gcctctgagg aaaactccaa tttaacaccc ctgatcacat gacgaggtct
     3061 tccctccttg gctgagcgtg agactccgag gccttggggg aagacccacc ctcccgtcac
     3121 tcacttcccc ccccaaggcc tcccgtcagt gacagaacat tctgccctcc acctttcacc
     3181 cctcagtcag tttggcaagt tttacgagct gcctcatgtc tgacacagaa ggagatacct
     3241 gtggtggaag atgctagaaa cggtcttgtc tgtagcatag tctaggactg gccaggggat
     3301 gacgccaagc tgacaatgcc attctgaggt tcccagtgat aaccgttgtt ctttggtgtc
     3361 cctgggccac gggagacctg tgtcctgaaa ttcaccattc tttcttccag gacaaaataa
     3421 ccctttctac catagttcat gatccgcgtc aactcagaca gtgaagctgg cagagaggag
     3481 tactggagtc tagaggggct gacgtgaaaa tcagctccag ggatggacaa ggattcttca
     3541 ctgttagtga gtggttctcc ctgcagcccg gggaaggaca gatcagcgga atgaagcgag
     3601 aggaatcccc aagtcactgt gtctcccggg atgtcagttt ggacgtctag agattaatct
     3661 ctctatacgt ttgcttcaga agaagaggtt cagggagcat agaggccaag ttgtgagcca
     3721 gacacaaaac ttcaggtttt aagtgaaaat caaagcagga aaaaaaaaac ttacatgaaa
     3781 agattgtaag ttgttcagtt tgtgtagcca tgataaacca aagagtgccc aggtcggcca
     3841 ggaagggtgc tccgtgctgt cacgggactt cactgtgctt gacacaggaa tgttgaatgc
     3901 tcacttttct tttccacata cccccacctc aagcctctta ctacatccct tgatggtaag
     3961 ctaagtattc caaaaaccta ccagatccag gggttttagt cctggatgtg ggggcagatg
     4021 caattctaat cataaccaca aggtggcaga atgaccgtgc atatctactc ctaagactaa
     4081 tgtaggtgtt gggaaacaca gccagcccaa gggaaattta aaagtcaagt ttgagtttct
     4141 gatttatttc ccaccccgtc cttgcacacc tccagccagt gcccagagac tcagtgctgc
     4201 ctgctgaatc tccaaaccat tccctagctg ccacccccag cccctgcccc tattcagtca
     4261 caggaaaata cttgcccaca ggaactttaa ctcaggggtt gttagcctgg ggcgttaccc
     4321 cagggcagtc catagtttga ctccagggga gctaaggagc ccttaaaact gtcggaacgt
     4381 agtgtttttg tgtgttttcc agagacataa gctttcttca tgttctcaaa gttcccagat
     4441 ccacgaaggc tttttaacag ttttaagtaa tggaactttc agcccaatgt ttctgcaatg
     4501 cagagcgaat actgggacac ttgagaatag tgtttaggta taggtggtca agcattcttg
     4561 tcggtggggc aaggttgaca cccacttaag acagggtcct cagaaatcgc tgacacatca
     4621 cacagtaggg tgacaaccta catcccatat aacttttgcc cactgtctac caaaaccaca
     4681 gtaggtgttg ccaagagggt cagcccacag gagggaagat tggagccaga gatgcttctt
     4741 cttcgtgtgt cactgacttc acatgcccct tgtttagcct ggctgccctg aggggccatg
     4801 catgtgttct agctaagtcc acgccacctc tccctacctg ctcctgcctg ctcggaatcc
     4861 agtgctagca cttagtgctg ggtgtctcag acctaggcca gtaagtgatg agtttggaac
     4921 aagatctcga aagggagcct gctaggtaaa tgaagttccc tctcattaac cctttggcca
     4981 cccctgctgt cacattagcc cctccctctg cagaacctct aagggacctg tcaccattcc
     5041 tttccctagc tcccaagccc cacccccacc ccagattttc ttcaggttaa aatacatttt
     5101 aaaaaagaga ttttaaaata aagcatttat gaagactcaa taaattgtaa ataattttta
     5161 aataaaataa aaaaaatgta tctcctgga
//
