LOCUS       NM_001106186            3553 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus cap methyltransferase 2 (Cmtr2), mRNA.
ACCESSION   NM_001106186 XM_001077341 XM_226458
VERSION     NM_001106186.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3553)
  AUTHORS   Werner M, Purta E, Kaminska KH, Cymerman IA, Campbell DA, Mittra B,
            Zamudio JR, Sturm NR, Jaworski J and Bujnicki JM.
  TITLE     2'-O-ribose methylation of cap2 in human: function and evolution in
            a horizontally mobile family
  JOURNAL   Nucleic Acids Res 39 (11), 4756-4768 (2011)
   PUBMED   21310715
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001077341.1, XM_226458.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ191924.1, FQ156277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..3553
                     /gene="Cmtr2"
                     /gene_synonym="Ftsjd1; RGD1309394"
                     /note="cap methyltransferase 2"
                     /db_xref="GeneID:292016"
                     /db_xref="RGD:1309394"
     exon            1..131
                     /gene="Cmtr2"
                     /gene_synonym="Ftsjd1; RGD1309394"
                     /inference="alignment:Splign:2.1.0"
     exon            132..3553
                     /gene="Cmtr2"
                     /gene_synonym="Ftsjd1; RGD1309394"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..2455
                     /gene="Cmtr2"
                     /gene_synonym="Ftsjd1; RGD1309394"
                     /EC_number="2.1.1.296"
                     /note="ftsJ methyltransferase domain-containing protein 1;
                     FtsJ methyltransferase domain containing 1"
                     /codon_start=1
                     /product="cap-specific mRNA
                     (nucleoside-2'-O-)-methyltransferase 2"
                     /protein_id="NP_001099656.1"
                     /db_xref="GeneID:292016"
                     /db_xref="RGD:1309394"
                     /translation="MSKRRKRPAQQPASPETFSPDALNAVSELFAKNFSYCKPLDHEW
                     QLPAPAESFTCEHVEFQAFLDLKNSLNAVKNLLCDKELDGWHRHTAFTNRAGQIIAHV
                     RKAVNAELCTQAWCKFQEILCSFPLIPQEAFQSGRLNSLHLCEAPGAFIASLNHYLKS
                     HRFPCEWSWVANSLNPYHEANDNLRMITDDRLIANTLHRWYFGPDNTGDIMTLKYLTG
                     LQDFLSGTSPIHLVTADGSFDCQGNPGEQEALVSPLHYCEAVTALTTLGDGGSFVLKM
                     FTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLCYKGREAIRPLLSRMV
                     LNFGTEMTKKALFPHHVIPKSFLERHRECCTLFHRYQLETISENIRLFECMGTGEQEK
                     LNNLRNCAVQHFMQKFQLKPLSRNHWLVKKSTLGCSTNTKWFGQRNKYFRTYNERKML
                     ETLSWKDKVARGFFDSWAEEHVVYHPGQSPLLEGSASSLECHLWCILEGKKLPKVKCS
                     PFCDSEILKTLNEAIEKSSGEALSVESKVSPKQQYRCCQIFSEESVLSELLSLTKCLQ
                     EEQGVEPSNPIRCLLVGSPTVRDLQMYTALEVQLLESVELTAFSCSLLHDGDPAYQHL
                     FLNCLLHSLKQLHSGDVMILPILSCFTRFMAGLTFVLHSCFRFITFSCPTSSEPLRTC
                     AVLLCIGYQNLPDPVFQFLQNVNELLGTLLHPGAPQQVLQFVPMEVLLQGTLLDFLWD
                     LNAAIAKRHLHLIIQGERDKVISSLEL"
ORIGIN      
        1 gaagctgttc ccgggagcgg aagtagcggg tggctcgcta gcgtgagtga ggaccgcgtg
       61 taccgtgcta ctgctccagc ccgtgcggct ctggtgggcg tgggctggag gaatgcggac
      121 ccgacttctc ggtttttaac ttggtctgaa aatgagcaag cgcaggaagc gtccagctca
      181 gcagccagcg agccccgaga ccttcagccc agacgctctc aatgccgtgt ctgagctctt
      241 cgccaagaac ttttcctact gtaagccact cgatcacgag tggcagttac cagctcccgc
      301 cgagagcttc acctgcgagc acgtcgagtt ccaagctttc cttgacttga agaactccct
      361 gaacgcagtg aaaaacctcc tgtgcgataa ggagctggac ggctggcaca ggcacaccgc
      421 cttcaccaac agggcggggc agatcatcgc ccacgtgaga aaggccgtga acgcagaact
      481 ctgtactcag gcctggtgca agttccagga gatcttgtgc agtttcccac ttatcccgca
      541 ggaagctttt cagagtggaa gactgaattc tctgcacctg tgtgaagccc caggcgcttt
      601 catagccagc ctcaaccatt acttaaaatc ccaccggttc ccctgtgaat ggagctgggt
      661 agcaaatagc ctgaacccat accacgaggc caacgacaat cttaggatga ttacggacga
      721 ccggctgatt gcaaacacct tgcaccgctg gtacttcggc ccagataaca ctggtgatat
      781 catgaccctg aagtacctga ccgggcttca ggacttcctc agcggcacat ctcccattca
      841 cttggtcact gctgatggga gttttgactg ccagggaaac ccaggcgaac aggaagcttt
      901 agtctcccct ttgcattact gtgaagctgt cactgctctg accacccttg gagatggtgg
      961 ctcttttgtt ctaaagatgt ttacgttgtt tgaacactgt tctgtgaacc tcatgtacct
     1021 gctaaattgt tcctttgacc aagttcacgt tttcaaacct gctactagca aggcgggaaa
     1081 ctcagaagtc tacgtggtgt gtctctgcta taagggaaga gaggctattc gtcctttgct
     1141 atctaggatg gtgttgaact ttggcactga gatgaccaag aaggcgctct ttccccatca
     1201 tgtgatcccc aaatcctttc ttgagcgaca cagagagtgt tgtacactct tccatagata
     1261 ccagttagag actatctctg agaacattcg tctttttgag tgcatgggga cgggggagca
     1321 agagaaactg aataacttaa ggaactgtgc tgtacagcat tttatgcaaa agttccaact
     1381 gaagcccctt tctagaaatc actggctcgt caaaaaatcc actcttggct gcagtacaaa
     1441 cacaaaatgg ttcggacaga gaaacaagta ttttagaacc tataacgaac ggaagatgct
     1501 ggaaaccctt tcgtggaagg ataaagtagc caggggattc ttcgatagtt gggcggagga
     1561 acatgtcgtc tatcaccccg ggcagagccc cctcctagaa gggagtgctt ccagcctcga
     1621 gtgccacttg tggtgcattc tagaaggcaa gaaactgccg aaggtgaagt gttctccttt
     1681 ctgtgatagt gaaattttaa agactcttaa tgaagccatt gagaagtcct caggagaagc
     1741 tttgagtgtg gagtccaagg tcagtcccaa gcagcaatac cgctgttgcc aaatcttctc
     1801 ggaagaatcg gtgttatccg agttgctgag ccttaccaag tgccttcagg aagagcaggg
     1861 tgtagaaccc agcaacccca tcaggtgcct gcttgtgggt tcacccactg tccgcgatct
     1921 ccaaatgtac acggccctgg aagtccagct tctggagtcc gtcgaactta ctgccttcag
     1981 ctgttcactg ctccatgacg gtgaccccgc ctaccaacat ttgtttttga attgcctgct
     2041 acactccctg aagcagcttc actcgggaga tgtgatgatt ttgcccatcc tttcctgctt
     2101 cacaaggttt atggctggct tgacctttgt cctccacagc tgttttagat ttatcacatt
     2161 ctcttgtccc acatcgtctg agcccctcag gacctgtgct gtcctgctat gcattggtta
     2221 tcagaacctt ccagatccag tttttcagtt tctgcagaac gttaacgaac tcttgggcac
     2281 tttgctccac cccggtgccc cccagcaggt tttacagttt gtaccaatgg aggtgctcct
     2341 tcaggggaca ctgcttgatt ttttgtggga tctgaatgct gccattgcta aaaggcattt
     2401 gcatttgatt atccaaggag agagagacaa agtcatcagc agcctcgagt tgtaaaattg
     2461 aacatggcgt tgttgatgtg tcgttttgca acttaacact ttgattccat tttacctgcc
     2521 ctatttattt aataattttc atcttggaga aatgccagtt tgtgtattaa aggacattaa
     2581 ttatggaaag tcatagcttg ttctgatcag aaggacatag gactggtagg tacagcgttt
     2641 ttgtggtagg aaccatgctc tgatggtgtc cagcctctaa tcatgtgaca tccgtgtgtg
     2701 ctcggggtga ctacacgctt gcttgcatat gcagctgagc tggtcttatc cagcctagca
     2761 ccgtgtgcct tcatccagac atcatccccc cactgattcc tctctgtctg atgctgttaa
     2821 tggtgaggtt agtcatgaca ggaggtgagt cactcttggc caccgctctt tacctggaaa
     2881 cacttgacac atctggattt cagggatctc tataccaggt ttcttgataa gtgccgttcc
     2941 ctgcttttag attgatggtt cggttttctt tgaattgatg tgaaatacgg agtttttgtg
     3001 tgactttttg cgagctataa gtatccaacc aatcaagcca aaaccaaagg tcatttctgt
     3061 acagtgaaga ttgtgtctag cactcctttg ttgtgaaaag cttccttcag caatgttggc
     3121 attttcattg tcctggaaag atggttctaa ggctcgtgta aagtctcctg tgggtgacag
     3181 cagagtgcgg tggtcacgga gaacacttga gggaaatgta acacttccag aatgacagct
     3241 ggacacattg ttaatctttg ccgtttattt ttttcagtac gaaaatagca ctttactaag
     3301 attatccgtg agatagatat tttatcaatt ttatttgatt ttgttgagta atatatattt
     3361 aataatatag tgaacttttc tagcaacagg ttaattcttc atcactttaa agtttttaga
     3421 tgtcatgtaa atgtttaggt attttctgtt ccttaaaaac atagaagtat tctgccatgt
     3481 atccagttaa taaatttttc atgctcttct atttttgagt tccattacaa ttcacaaata
     3541 aagccttcag cag
//
