LOCUS       NM_001106164            1519 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  Rattus norvegicus CKLF-like MARVEL transmembrane domain containing
            3 (Cmtm3), mRNA.
ACCESSION   NM_001106164 XM_001054851 XM_226200
VERSION     NM_001106164.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Ye J, Yan S, Liu R, Weng L, Jia B, Jia S, Xiong Y, Zhou Y, Leng M,
            Zhao J, Yang F and Zheng M.
  TITLE     CMTM3 deficiency induces cardiac hypertrophy by regulating MAPK/ERK
            signaling
  JOURNAL   Biochem Biophys Res Commun 667, 162-169 (2023)
   PUBMED   37229825
  REMARK    GeneRIF: CMTM3 deficiency induces cardiac hypertrophy by regulating
            MAPK/ERK signaling.
REFERENCE   2  (bases 1 to 1519)
  AUTHORS   Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P,
            Zhu C, Kros JM, Duncker DJ and Cheng C.
  TITLE     CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates
            Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin
            in Endothelial Adherens Junctions
  JOURNAL   Arterioscler Thromb Vasc Biol 37 (6), 1098-1114 (2017)
   PUBMED   28428220
REFERENCE   3  (bases 1 to 1519)
  AUTHORS   Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD and Mager J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1519)
  AUTHORS   Wilm B, James RG, Schultheiss TM and Hogan BL.
  TITLE     The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus
            intermediate mesoderm cell fate
  JOURNAL   Dev Biol 271 (1), 176-189 (2004)
   PUBMED   15196959
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474006.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_226200.3, XM_001054851.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169107.1, FQ227380.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434, SAMN06680420
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p14"
     gene            1..1519
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /note="CKLF-like MARVEL transmembrane domain containing 3"
                     /db_xref="GeneID:291813"
                     /db_xref="RGD:1308763"
     exon            1..216
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..624
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /note="chemokine-like factor super family 3"
                     /codon_start=1
                     /product="CKLF-like MARVEL transmembrane domain-containing
                     protein 3"
                     /protein_id="NP_001099634.1"
                     /db_xref="GeneID:291813"
                     /db_xref="RGD:1308763"
                     /translation="MWPRDAEPEPDPESTHGPRSGRTVPGLRALLPARAFLCSLKGRL
                     LLAESGLSFITFVCYVVSSASAFLTVPLLEFLLAIYFLFADAMQLNDKWQGLCWPMMD
                     FLRCVTAALIYFVISITAVAKYSEGAYKAAGVFGFFATIVFAIDFYLIFNEVAKFLKQ
                     GDSGNETTAHRTEEENSNSDSDSD"
     exon            217..372
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            373..468
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            469..589
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            590..1519
                     /gene="Cmtm3"
                     /gene_synonym="Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggtttccg cttccctcca gagcggtggg tgagactgtg aggccgaggc tcgaccagat
       61 agcgccgcta tgtggccccg ggacgcagag ccagagcccg acccggagtc cacgcatggc
      121 ccccgaagtg gcaggacagt gccggggctc cgagccctgt tgcccgcacg cgccttcctc
      181 tgctctctta aaggccgcct cctgctggcc gagtcgggcc tttcattcat taccttcgtc
      241 tgctatgtgg tatcctcggc atctgccttc ctcacagtgc ctcttctgga gtttctgttg
      301 gccatctact tcctctttgc tgatgccatg cagctgaatg acaagtggca gggcttgtgc
      361 tggcccatga tggacttcct gcgctgtgtc acggctgctc tcatctactt cgtcatctcc
      421 atcactgctg tcgccaaata ctcagaaggg gcttacaagg cagcaggagt ttttggcttt
      481 tttgccacaa ttgtgtttgc cattgacttc tacctgatct ttaatgaagt ggccaaattc
      541 ctcaagcaag gagactctgg gaacgagacc acagcccata ggacagaaga agagaattcc
      601 aactctgact cagattctga ctgaaggact gtctgcgctt gccaactgga gccactcagc
      661 cctctcaccc ataccgtccc cacgtggcta caggagcatg gcagggaatg cccacgggag
      721 agcagagtga ggcctcaact cacaattggc tgttggcttg gtgctgctga gctagcatgg
      781 tagggctcgt tgaacatcct cccttctcct ttctgtcttt gggccccttt aacctctttg
      841 ccccacagaa gcacacgcca aacagagcca atcactgcag ttcatgtagc agcatggggt
      901 gcggtgagac ttccttttat taacagggac agacaaaacc acagcaggct gggccaccag
      961 ccccagcctg cacagagtgt ttctgttcac gcctgcactt cggttgatag gactttcagg
     1021 aatctttgtt caagaagttt ccctcctcac tgtgaaacag ggagaaactt aactagccaa
     1081 gtcttccact gggggtctga gacctttgca gaaaggaacc caaagacttg tttaccacgg
     1141 cccacagaca gggagccaac caatacagtg gcagtgacca agtcacaagt ggctgggcag
     1201 gcccagccaa gcactctcct cctggggatc ctaaaaggta aagtgcttcc tccagacacc
     1261 tgggcaggac caccagtgac atgggccttc tatcccttgg gggctgatac tgtgtatgtg
     1321 tctttgatgg ggttttcttt ttttatattt ttttttatac aaaaacaatg taacaaatgg
     1381 ccttttctgt aacccaagag gccccaggaa tgagccagag ttctgggccc atgttttggg
     1441 catttgtaac cttcttatct tgcatgtgaa tcctctccct aaaaaaaatt gccacaatgg
     1501 attaaaacaa actgactac
//
