LOCUS       NM_012961               1798 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus chemerin chemokine-like receptor 2 (Cmklr2),
            mRNA.
ACCESSION   NM_012961 XM_008767077
VERSION     NM_012961.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Kennedy,A.J., Yang,P., Read,C., Kuc,R.E., Yang,L., Taylor,E.J.,
            Taylor,C.W., Maguire,J.J. and Davenport,A.P.
  TITLE     Chemerin Elicits Potent Constrictor Actions via Chemokine-Like
            Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in
            Human and Rat Vasculature
  JOURNAL   J Am Heart Assoc 5 (10), e004421 (2016)
   PUBMED   27742615
  REMARK    GeneRIF: CMKLR1 and GPR1 were widely expressed in vascular smooth
            muscle.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  AUTHORS   Marchese,A., Cheng,R., Lee,M.C., Porter,C.A., Heiber,M.,
            Goodman,M., George,S.R. and O'Dowd,B.F.
  TITLE     Mapping studies of two G protein-coupled receptor genes: an amino
            acid difference may confer a functional variation between a human
            and rodent receptor
  JOURNAL   Biochem Biophys Res Commun 205 (3), 1952-1958 (1994)
   PUBMED   7811287
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Oct 11, 2022 this sequence version replaced
            XM_008767077.3, NM_012961.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1065723.1,
                                           SRR26360194.54571.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09345238
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000009.1  72111612-72111735   c
            125-274             JAXUCZ010000009.1  72107404-72107553   c
            275-1798            JAXUCZ010000009.1  72079016-72080539   c
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q32"
     gene            1..1798
                     /gene="Cmklr2"
                     /gene_synonym="Gpr1"
                     /note="chemerin chemokine-like receptor 2"
                     /db_xref="GeneID:25457"
                     /db_xref="RGD:2728"
     exon            1..124
                     /gene="Cmklr2"
                     /gene_synonym="Gpr1"
                     /inference="alignment:Splign:2.1.0"
     exon            125..274
                     /gene="Cmklr2"
                     /gene_synonym="Gpr1"
                     /inference="alignment:Splign:2.1.0"
     exon            275..1798
                     /gene="Cmklr2"
                     /gene_synonym="Gpr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             305..1366
                     /gene="Cmklr2"
                     /gene_synonym="Gpr1"
                     /note="probable G-protein coupled receptor 1; G-protein
                     copled receptor 1; G protein-coupled receptor 1;
                     chemokine-like receptor 2"
                     /codon_start=1
                     /product="chemerin-like receptor 2"
                     /protein_id="NP_037093.2"
                     /db_xref="GeneID:25457"
                     /db_xref="RGD:2728"
                     /translation="MEVSREMLFEELDNYSYALEYYSQEPDAEENVYPGIVHWISLLL
                     YALAFVLGIPGNAIVIWFMGFKWKKTVTTLWFLNLAIADFVFVLFLPLYISYVALSFH
                     WPFGRWLCKLNSFIAQLNMFSSVFFLTVISLDRYIHLIHPGLSHPHRTLKNSLLVVLF
                     VWLLASLLGGPTLYFRDTVEVNNRIICYNNFQEYELTLMRHHVLTWVKFLFGYLLPLL
                     TMSSCYLCLIFKTKKQNILISSKHLWMILSVVIAFMVCWTPFHLFSIWELSIHHNSSF
                     QNVLQGGIPLSTGLAFLNSCLNPILYVLISKKFQARFRASVAEVLKRSLWEASCSGTV
                     SEQLRSAETKSLSLLETAQ"
ORIGIN      
        1 agttctccca gagaaatcat taaacctgaa ggatcctaag cacggagccc ggaagacaag
       61 acgtagcagc tcgccatcca gcctcccagc ttccccaccg atccagcaca ggcacctttt
      121 agggtgtcat ttcaaaagtc aaagaaaacc tgtctggggt ggctagaaaa gagagtgcag
      181 cttgagtgac tggaacactc cctccatttc agtctggagt tggaggtcat attcaaacac
      241 cacaacagct tggcccctca cagaacatta acagatttcc tcactctcca cctataagat
      301 catcatggaa gtctcaaggg aaatgctatt tgaagaactg gacaactact cctatgcctt
      361 agaatattac tcccaggaac ctgacgcaga ggagaatgtg tacccgggaa tcgttcactg
      421 gatctccctg ctcttatatg cccttgcgtt tgttctggga attccaggga atgccatcgt
      481 catttggttc atgggattca agtggaagaa gacggtcacc actctttggt ttctcaatct
      541 ggccattgca gacttcgtct ttgttctctt cctgcctctg tatatttcct atgtggcact
      601 gagtttccac tggccctttg gccgatggct ctgcaagctt aattccttca ttgcccaact
      661 gaacatgttt tccagtgtat tcttcttgac agtgattagc ctggaccgct acattcactt
      721 gatccaccct ggcttgtctc atccgcaccg gaccctgaag aactcactgc ttgttgttct
      781 atttgtctgg ctgttggctt ctctgctcgg aggtcctacc ctgtacttcc gggacaccgt
      841 ggaggtcaac aaccgcatta tttgttataa caacttccag gagtatgagc tcaccctgat
      901 gagacaccac gttctgacct gggtgaagtt cctttttggc tacctcttgc ctttgctgac
      961 aatgagctcc tgctacctgt gcctcatctt caagacgaag aagcaaaaca ttctgatatc
     1021 cagtaagcat ctctggatga tcctgtctgt ggtcatcgcc ttcatggttt gctggactcc
     1081 ttttcacctg ttcagcattt gggaactcag cattcatcac aacagctctt tccagaacgt
     1141 gctgcagggc ggaatccctc tctctactgg cttggccttc ctcaacagct gcttgaaccc
     1201 catcctttac gttctaataa gcaagaagtt tcaagctcga ttcagggcct ctgttgccga
     1261 ggtactaaag cggtcactgt gggaggccag ttgctctggt acagtgagtg aacaactcag
     1321 gagtgctgaa accaagagcc tgtctctcct agaaactgcc caatgagtat tttgtgccca
     1381 gaaaaccagt gcaaagtttc tgtgggagcc tcataaccaa tcctttcaga ttaggatttg
     1441 ttccgatcta aaatgattgt atttttgttc ggttacgttt ttgcgtgggt ataaaaggca
     1501 ggatctcttc cttgcaattt aaatcatgta tctttctgcc tgccctctgg tggcaattct
     1561 gatactgaca ccctaaaagt ttcccccact cttttagcct tcgtctatta atgtacgcaa
     1621 tatatgtatc agattaaata atttttatag tgtataccac atcatattaa tcatctctgt
     1681 tgaaaaacta tcaggctgac tttttttctg gtttgctttt gagtcatttt gtgtgtatgt
     1741 taatgtattt atagatgtac atgtatgtaa actgtaacta aatcattttt ctcatgga
//
