LOCUS       NM_134377               4378 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Rattus norvegicus calsyntenin 2 (Clstn2), mRNA.
ACCESSION   NM_134377 XM_346832
VERSION     NM_134377.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4378)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
  REMARK    Erratum:[Cell Rep. 2024 Aug 27;43(8):114646. doi:
            10.1016/j.celrep.2024.114646.. PMID: 39110596]
REFERENCE   2  (bases 1 to 4378)
  AUTHORS   Hintsch,G., Zurlinden,A., Meskenaite,V., Steuble,M.,
            Fink-Widmer,K., Kinter,J. and Sonderegger,P.
  TITLE     The calsyntenins--a family of postsynaptic membrane proteins with
            distinct neuronal expression patterns
  JOURNAL   Mol Cell Neurosci 21 (3), 393-409 (2002)
   PUBMED   12498782
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 1, 2022 this sequence version replaced NM_134377.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ427342.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-313               JAXUCZ010000008.1  107516090-107516402 c
            314-436             JAXUCZ010000008.1  107270701-107270823 c
            437-632             JAXUCZ010000008.1  107039242-107039437 c
            633-841             JAXUCZ010000008.1  107038193-107038401 c
            842-991             JAXUCZ010000008.1  107025535-107025684 c
            992-1177            JAXUCZ010000008.1  106997874-106998059 c
            1178-1426           JAXUCZ010000008.1  106988567-106988815 c
            1427-1548           JAXUCZ010000008.1  106983607-106983728 c
            1549-1711           JAXUCZ010000008.1  106939734-106939896 c
            1712-1878           JAXUCZ010000008.1  106926362-106926528 c
            1879-2027           JAXUCZ010000008.1  106919435-106919583 c
            2028-2251           JAXUCZ010000008.1  106917206-106917429 c
            2252-2422           JAXUCZ010000008.1  106913771-106913941 c
            2423-2568           JAXUCZ010000008.1  106913223-106913368 c
            2569-2692           JAXUCZ010000008.1  106912989-106913112 c
            2693-2877           JAXUCZ010000008.1  106912109-106912293 c
            2878-3035           JAXUCZ010000008.1  106910230-106910387 c
            3036-4378           JAXUCZ010000008.1  106899894-106901236 c
FEATURES             Location/Qualifiers
     source          1..4378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..4378
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /note="calsyntenin 2"
                     /db_xref="GeneID:171394"
                     /db_xref="RGD:621151"
     exon            1..313
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..3096
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /note="alc-gamma; alcadein-gamma"
                     /codon_start=1
                     /product="calsyntenin-2 precursor"
                     /protein_id="NP_599204.2"
                     /db_xref="GeneID:171394"
                     /db_xref="RGD:621151"
                     /translation="MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLAAKVNKHKP
                     WIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKT
                     SGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPQEAAWKKSHKAVVHIQVKDVNEFAP
                     TFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIR
                     NTEKLSYDKQRQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGS
                     GSMPLFPGIHLETCDGAVSSLQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIID
                     LLPSPSAATNWTAGLLVDSSEMIFKFDGRQGAKIPDGIVPKNLTDQFTITMWMKHGPS
                     PGVRAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHWKLDQ
                     ICDKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACWQGGEV
                     AKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINSLESLGRGIKYHFNPS
                     QSILVMEGDDIGNINQALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVD
                     AYIMVLQAIEPQITLQGTERFWRPAAQFESARGVTLFPDIKIISTFAKTEASGDLRAT
                     GTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATNSTAGYSI
                     YGVGSMSRYEQVLHHLRYRNWHPTSLETRRFQIKCSELNGRYTSNEFNLEVSVLHEVR
                     VSDTEHVNHLIVQPPFLQSVYHPETRSSIQRSSVVPSIATVVIIISVCMLVFVVAMGV
                     YRVRIAHQHFIQETEAAKEAEMDWDDSALTITVNPMEKHEGPGHGEDETEGEEEEEAE
                     EGMSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQRPERSTWNTAGVINIWK"
     exon            314..436
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            437..632
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            633..841
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            842..991
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1177
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1426
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1548
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1711
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1878
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2027
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2251
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2252..2422
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2568
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2569..2692
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2877
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2878..3035
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3036..4378
                     /gene="Clstn2"
                     /gene_synonym="Cs2; Cstn2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgagtgct gctgttgccg gcgaacgagc ggcgcggcga agggcagccg aggcggtggg
       61 tgagggcggc ggcggttcct gaagcgcacc cggcagctac agcgaggcgg cgcggcaagc
      121 accagcggac accggcaggc gaggcgggcg cgggcggtag gcggcggcgg cagctcggtg
      181 gcggctgagg cggcgaggat gctgccgggg aggctgtgct tggtgccgct cctgctggcg
      241 ctgggcgtag ggagcggcgg aggcagcggc gacggcgggg acagccggcg gcgccgcctc
      301 ctcgcggcga aagtcaataa acacaagcca tggatcgaga catcgtatca tggagtcata
      361 actgagaaca atgacacagt catcttggac cctcctctcg tagccctgga caaagacgcc
      421 ccagtgccat ttgcagggga aatctgcgca ttcaagatcc atgggcagga gctgcctttt
      481 gaagctgtgg tgctcaataa gacatctgga gagggccggc tccgtgccaa gagtcccatc
      541 gactgtgagc tacagaagga gtacacattc atcatccagg cctatgactg tggtgcagga
      601 cctcaggaag cagcctggaa gaagtcacac aaggctgtgg tccacatcca ggtgaaggat
      661 gtcaatgagt tcgcacccac cttcaaagaa ccagcctaca aagccatcgt cacagagggc
      721 aagatctatg acagcatcct gcaggtagaa gccatcgatg aggactgctc cccccaatac
      781 agccagattt gcaactatga aattgtcacg acggatgtgc cttttgccat tgacagaaat
      841 ggcaacatca gaaacactga gaagctgagc tatgacaagc aacgccagta tgagatcctg
      901 gtaactgctt atgactgtgg acagaagccc gctgctcagg acaccctggt ccaggtggat
      961 gtgaagccag tgtgtaagcc tggctggcaa gattggacca aaaggattga gtaccagccc
     1021 ggctcaggga gtatgccctt gttccccggc atccacctgg agacgtgcga cggagctgtg
     1081 tcctccctcc aggtcactgc agagctgcag actaattaca tcggcaaggg ctgtgaccga
     1141 gagacctact ctgagaaatc ccttcagaaa ctatgtggag catcctcggg catcatcgac
     1201 ctcttgccat cccctagtgc ggctaccaac tggactgctg gactcctggt ggacagcagt
     1261 gagatgatct tcaagtttga tggcaggcag ggtgccaaga tcccagatgg gattgtgccc
     1321 aagaacctga cagaccagtt caccatcaca atgtggatga aacatggccc cagccctggc
     1381 gtgagagctg agaaggaaac catcctctgt aactcagata aaactgaaat gaaccggcat
     1441 cactatgcct tgtatgtgca caactgccgc cttgtcttcc tcctgcggaa ggactttgac
     1501 caggcagaca cctttcgccc cgcagagttt cactggaagc tggaccagat ttgtgacaaa
     1561 gagtggcatt actatgtcat caatgtggag ttccctgtgg tcaccttgta catggatgga
     1621 gcaacatatg aaccatacct ggtgaccaat gactggccca ttcatccatc tcacatagcc
     1681 atgcaactca ctgtcggcgc ctgttggcaa ggaggtgaag tggccaaacc acggtttgca
     1741 caatttttcc atggcagcct tgccagtctc acaatccgtc ctggcaaaat ggaaagccag
     1801 aaggtgattt cttgtttgca ggcctgcaaa gaagggctgg atattaattc cttggaaagc
     1861 cttggccgag ggataaagta tcacttcaac ccttcacagt ccatccttgt gatggaaggc
     1921 gatgacattg ggaacatcaa ccaagccctc cagaaagtct cctacatcaa ctccaggcag
     1981 ttcccaacag caggggtccg gcgcctcaga ctctcttcta aagtccagtg ctttggggaa
     2041 gacgtgtgca tcagcatccc agatgtggat gcctacatca tggtcctgca ggccatcgag
     2101 ccccagatca ccctccaggg aacagagcgt ttctggagac ctgctgccca gttcgaaagt
     2161 gccagaggag tgactctctt ccctgacatc aagatcatca gcacctttgc caagactgag
     2221 gcctctgggg acttgagagc tacaggcaca gcccccaaat cggcagtctt ggaagaaatg
     2281 ctacataatt tggatttctg tgatattttg gtgcttggag gggacttgga tccaagacaa
     2341 gagtgcttgg agctcaacca cagtgagctc caccaacgac accttgatgc caccaactct
     2401 actgctggct actctatcta tggtgtgggg tccatgagcc gttatgagca ggtactgcac
     2461 cacctccgtt accgcaactg gcaccccact tcccttgaga ctcggaggtt ccagatcaag
     2521 tgttcagagc tcaatgggcg ttacaccagc aatgagttca acttagaggt cagtgtcctc
     2581 catgaagtta gagtctctga tacggaacat gtcaaccatc ttattgtgca gccacccttc
     2641 ctccagtctg tctatcaccc tgagacccgg agtagtatcc agcgcagttc agtggtcccg
     2701 agcatcgcca ctgtggtcat cattatctct gtgtgcatgc tagtgtttgt tgtggccatg
     2761 ggtgtgtacc gagtccgaat tgcccaccag cattttatcc aagagactga ggctgccaag
     2821 gaggctgaaa tggattggga tgactctgca ctgactatca cagtcaaccc tatggagaaa
     2881 catgaaggac cagggcatgg agaagacgag actgaaggag aggaagaaga agaagcagag
     2941 gaaggcatga gctccagcag cagtggctct gatgacagtg aagaggaaga agaggaaggg
     3001 atgggcagag tcagacatgg gcagagtggc accagctctc aacgccctga aagaagtacc
     3061 tggaatacag caggagtcat aaacatttgg aagtgaagca cctagcttgt ccctacttgg
     3121 tgaagacccg atatatcact aacaaccata ttgactgagt catatagaag caggtcaacc
     3181 atgcgactct cccagcttag agaagccttt gtgaattttc atatttcgtg cagtagtcag
     3241 acagtggcag acactgggtc tgggtcttag gcagtgaaca gtgacagtgt tgcacatagt
     3301 tgcttgcaca catttagaac acgcctgaat aacacccaca atgctgcttc tgcagagtag
     3361 tctgtccaac ctaccattgt ctctgtcttg ccctgagtac ttgctaaata ctgttcactc
     3421 catcatcttt cgtcattgat gctgggacta aatataaagg ttccgggttc agccaatctc
     3481 agacccttct gtcctcccat gtctggagat gttggcacca tttcaaagcc ttgtatgaga
     3541 aaccagtttg tccccagttc ctcaacctca gtgcatggga aaggcctgag atgggcaggc
     3601 tgcttgctct actggagcct ttctggcatt cactctgcag agagaaagag cagcctcatt
     3661 gtacgcaacc accttccacc tgcacctgac tgcaaagtag cctaatggtc agtgcagccg
     3721 gagtgtcttt gctgggagcc agctgcactt ggggattgtg tgttcttggc acacagcaga
     3781 cttctgagcc tcttgaactg cctccaagaa tgaatctcgt tagtctacaa aatatattta
     3841 tttggtaact atgctactgt gtgtgtatga gtctgataca atgcaaacct tgaaatgtct
     3901 tactaaaagg acttatgaat tcataggaaa ttggatccaa cttcagaata gcgaattatg
     3961 ttgctggtca ataaagttgc ccagccacaa gggaccagag aaaaaccttc ccccccatcc
     4021 cttttttgac accctttccc tgcctaattg ccctactaga ttctaactga tgcagagtga
     4081 agaaaggtgc tgacagagta catgtgcata aagattgaag agggaaatga cctctggggc
     4141 aatcagtcga gtttcttccc atggctgtga tcctatcatg cctgattccc aaacttgcaa
     4201 tttctaacaa tttcgattct tggagtttct gagcaatttg ttaaatgcct gttcaacaca
     4261 gacagatatt tattttcagc cttggcttgg aaatgcctac aaactgattc atgttggtgg
     4321 tcgttctgac acttctgtga attggttgaa taaatatgat tttagaattt cacagtaa
//
