LOCUS       NM_001395082            5275 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus claspin (Clspn), mRNA.
ACCESSION   NM_001395082 XM_039109633
VERSION     NM_001395082.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5275)
  AUTHORS   Bassermann,F., Frescas,D., Guardavaccaro,D., Busino,L.,
            Peschiaroli,A. and Pagano,M.
  TITLE     The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response
            checkpoint
  JOURNAL   Cell 134 (2), 256-267 (2008)
   PUBMED   18662541
REFERENCE   2  (bases 1 to 5275)
  AUTHORS   Chini,C.C. and Chen,J.
  TITLE     Repeated phosphopeptide motifs in human Claspin are phosphorylated
            by Chk1 and mediate Claspin function
  JOURNAL   J Biol Chem 281 (44), 33276-33282 (2006)
   PUBMED   16963448
REFERENCE   3  (bases 1 to 5275)
  AUTHORS   Peschiaroli,A., Dorrello,N.V., Guardavaccaro,D., Venere,M.,
            Halazonetis,T., Sherman,N.E. and Pagano,M.
  TITLE     SCFbetaTrCP-mediated degradation of Claspin regulates recovery from
            the DNA replication checkpoint response
  JOURNAL   Mol Cell 23 (3), 319-329 (2006)
   PUBMED   16885022
REFERENCE   4  (bases 1 to 5275)
  AUTHORS   Chini,C.C. and Chen,J.
  TITLE     Human claspin is required for replication checkpoint control
  JOURNAL   J Biol Chem 278 (32), 30057-30062 (2003)
   PUBMED   12766152
REFERENCE   5  (bases 1 to 5275)
  AUTHORS   Calderari,G.
  TITLE     [Inlays in the prosthetic rehabilitation of the periodontal
            patient]
  JOURNAL   Dent Cadmos 34 (11), 1509-1537 (1966)
   PUBMED   5226314
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jun 3, 2021 this sequence version replaced XM_039109633.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.23033.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-158               JAXUCZ010000005.1  144134637-144134794
            159-255             JAXUCZ010000005.1  144136705-144136801
            256-683             JAXUCZ010000005.1  144137577-144138004
            684-845             JAXUCZ010000005.1  144139591-144139752
            846-923             JAXUCZ010000005.1  144142019-144142096
            924-996             JAXUCZ010000005.1  144142812-144142884
            997-1105            JAXUCZ010000005.1  144143770-144143878
            1106-1680           JAXUCZ010000005.1  144144051-144144625
            1681-1872           JAXUCZ010000005.1  144149886-144150077
            1873-2099           JAXUCZ010000005.1  144151379-144151605
            2100-2275           JAXUCZ010000005.1  144152849-144153024
            2276-2340           JAXUCZ010000005.1  144153292-144153356
            2341-2537           JAXUCZ010000005.1  144154041-144154237
            2538-2692           JAXUCZ010000005.1  144154543-144154697
            2693-2922           JAXUCZ010000005.1  144155788-144156017
            2923-3034           JAXUCZ010000005.1  144156517-144156628
            3035-3110           JAXUCZ010000005.1  144159798-144159873
            3111-3208           JAXUCZ010000005.1  144160263-144160360
            3209-3373           JAXUCZ010000005.1  144162880-144163044
            3374-3495           JAXUCZ010000005.1  144163142-144163263
            3496-3623           JAXUCZ010000005.1  144164635-144164762
            3624-3726           JAXUCZ010000005.1  144166238-144166340
            3727-3809           JAXUCZ010000005.1  144166904-144166986
            3810-3971           JAXUCZ010000005.1  144167187-144167348
            3972-5275           JAXUCZ010000005.1  144168228-144169531
FEATURES             Location/Qualifiers
     source          1..5275
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5275
                     /gene="Clspn"
                     /note="claspin"
                     /db_xref="GeneID:298534"
                     /db_xref="RGD:1309083"
     exon            1..158
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..4082
                     /gene="Clspn"
                     /codon_start=1
                     /product="claspin"
                     /protein_id="NP_001382011.1"
                     /db_xref="GeneID:298534"
                     /db_xref="RGD:1309083"
                     /translation="MTGEVDSEVNLEVGDLKILSQEEVDSGQGSFEALELFSERDSDE
                     EIFVSKKPKSRKVLQDSDSEAEDNAPEKPTYDSAEENNENLHSGKSQTIKSISTALAD
                     SDESSMEGTPCQESLETQETPSLELSHQTASSADFTTDRKLSKALRREGTEGKAKSKR
                     RLEKEERTREKIRRLKKKETRCEESDADRPLNDSGCLLEDSDLFETGLEEEDDSPLED
                     EESLESIRAAVKNKMKNHKKKEPSLESETFSLEDESELSKGSGRKERKAAKLSKEALK
                     KLHSETQRLVRESALNLPYHMPESKTIHDFFKRKPRPSCQGSAMALLKSCKYQSGHHK
                     EAINPADAAGMSADDPSKGSEQRTRAESAKETTILPEVSEEAGITAGSDEACGKDPVR
                     GAELEIEETEKYSDGRPSPGDRSVSQQESSISRSKDSENCHTGELTQSDPPALEGEEL
                     KTTEEAEAGEGAAEQKTESAVAPPGKARRFTVDRLRQLGVDVSSQPRLGADEDSFVIL
                     DEPETNRELEALKQRFWRHANPAASPRAHQTLNVNIIVKDLGTDGKEELKAEVVPVTL
                     AAEKLEGASHTKPGEKLQMLKAKLQEAMKLRRLEERQKRQALFKLDNEDGFEEEEEEE
                     EMTDESEEDGEEEEEEEEEEEEEEEVGDMQETSEYLLGSEDTETKAEKETDKENTDAS
                     SDVGKPVALSVPKPLSSDSTLLLFKDTSSKMGYFPTEEKSETDEHMGKQSDKLDEDDS
                     SSLLTKESSHNSSFELIGSTIPSYQPCNRHTGRGTSFLPTAGFRSPSPGLFRGSLISS
                     ASKSSGKLSEPSLPIEDSQDLYTASPEPKTLFLGAGDFQFCLEDDTQSQLLDADGFLN
                     VRNHRNRYQALKPQLPLASMDENAMDANMDELLDLCTGQFTSQSEEKCQPRKNDQKEN
                     MEELLNLCSGKFPSQDASPVAPLELRTEERESGTEDPMEEALALCSGSFPTDREEEGE
                     EEEFGDFQLVSKENEFASDEGGHSDSSDEELALDLEDDEEELLKQSEKMKRQMRLKKY
                     LEDEAEVSGSDVGSEDEYDGEDIDEYEEDAIDEVLPSDEELESQIKKIHMKTMLDDDK
                     RRLRLYQERYLADGDLHSDGPGRTRKFRWKHIDDTSQMDLFHRDSDDDQVEEQLDETE
                     AKWRKERIEREQWLREQAQQGKIAAEEEDVGEDSQFMMLAKKVTAKALQKNASRAVAV
                     QESKSVLSNPFETIRAGGAHQLKTGSLLNQPKAVLQKLATLSDLNPSAPRNSRNFVFH
                     TLSPTKAETAKSSSKPQVRRRGPSSMMSPSPKRLKTNDSSPGPKRSIFRYLES"
     exon            159..255
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            256..683
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            684..845
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            846..923
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            924..996
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1105
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1680
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1872
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..2099
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2100..2275
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2276..2340
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2537
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2692
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2922
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            2923..3034
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3110
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3111..3208
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3209..3373
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3374..3495
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3496..3623
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3624..3726
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3727..3809
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3810..3971
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
     exon            3972..5275
                     /gene="Clspn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgagcgctgt accgcgtctg ggcgcgaaag ctcgaacttc gctgccgggc tggagacggc
       61 gggagctgtc gctggcaagt caaggttact ggggacgcgt tctcctggag ccgcgcggta
      121 gggaggccgg aatcatgacc ggcgaggtgg attctgaggt taacctggaa gtcggtgatc
      181 taaaaatcct ttcacaagaa gaagtagaca gtggacaggg cagctttgaa gcactcgagc
      241 tctttagtga aagagattct gacgaagaga tatttgtgag taagaagccg aagagcagga
      301 aagtgttaca agacagcgat tctgaggctg aggacaatgc tccagagaaa cccacctacg
      361 acagtgcgga ggagaataat gagaacttac actcggggaa gagtcagacg atcaaaagca
      421 tctccaccgc tctggctgac agtgacgaga gcagcatgga gggaactccg tgtcaggaga
      481 gtcttgagac tcaagagact ccttccttgg agctgagcca ccagacagca agctctgcgg
      541 acttcaccac cgacagaaag ctctccaaag cactccgcag agaaggaact gaaggaaaag
      601 caaaatccaa gagaagactg gagaaagagg agagaacaag ggagaaaatt aggagactga
      661 aaaagaagga aacaagatgt gaggaaagtg atgcagaccg gccacttaac gacagtggct
      721 gtcttcttga agatagtgat ctttttgaga caggtttgga ggaagaagat gactctccac
      781 tggaagatga ggagtcatta gagtcaatca gggcggctgt caaaaacaag atgaagaatc
      841 acaagaaaaa ggaaccatcc ctggagagtg agaccttttc attagaagat gaaagtgagt
      901 tatccaaagg cagtgggagg aaggaaagaa aggcagcaaa gttaagtaaa gaagcactaa
      961 aaaaactgca tagtgagact cagcgtctag tccgagaatc tgcacttaat cttccatatc
     1021 atatgcctga gagtaaaact attcacgatt tcttcaaacg gaagccccgg cccagttgcc
     1081 agggcagcgc catggccctg ctgaagtcat gtaagtatca gtcgggccac cacaaggaag
     1141 ccataaaccc ggcagatgca gctggaatga gtgccgatga ccccagtaaa ggttctgagc
     1201 agagaacaag ggcagaaagt gcaaaggaaa ctaccattct ccctgaggtc tcagaagaag
     1261 ccgggatcac tgctggatca gatgaggctt gtgggaagga tccggtaaga ggagcagagc
     1321 tggaaattga ggagactgag aagtacagtg atggcagacc ttctcctggg gacagatccg
     1381 tgtcacagca agaatcctcc atctccagga gcaaagacag tgagaactgt cacactggag
     1441 aactcaccca gtccgaccct cctgccttgg agggagaaga actgaaaaca acagaagaag
     1501 cagaggcagg agagggagca gccgagcaga aaactgagtc agccgtggcg ccacctggaa
     1561 aggcgagacg attcactgtg gaccgactta gacagctagg cgtggatgtt tccagtcagc
     1621 ctcggctggg tgctgatgaa gattccttcg tgatacttga tgaacctgaa accaacagag
     1681 aactggaagc cttgaagcag cgcttctgga ggcatgctaa cccagcagcc agtcccaggg
     1741 cgcatcagac gctgaatgtg aacatcatcg tgaaggactt gggcactgac gggaaggagg
     1801 agctgaaggc agaagtggtg cccgtcactt tggcagcaga gaagctggaa ggagcgagcc
     1861 acacaaaacc aggtgaaaaa ctgcagatgt taaaagctaa gttgcaggag gcaatgaaac
     1921 tccgaaggct cgaggagcgg cagaagcgcc aagcgttgtt taaattagat aatgaagatg
     1981 gatttgaaga ggaggaggaa gaggaagaaa tgacagatga gtctgaggaa gatggagaag
     2041 aggaagaaga ggaggaggag gaggaggagg aggaggagga ggttggagac atgcaggaga
     2101 cttcagaata tcttcttggc agtgaagata cagaaaccaa agctgaaaaa gaaacagata
     2161 aagaaaacac agacgccagt agtgacgtcg gcaaacctgt tgccctctct gtccccaagc
     2221 ccctgtcctc ggactccacc ttacttctgt ttaaggacac ctcttccaag atgggttact
     2281 ttcctactga agaaaaatca gaaacagatg aacacatggg caagcagtct gacaaactgg
     2341 atgaagacga ctcaagttca ctgctaacaa aagagagcag ccacaacagc agctttgagc
     2401 tcattggctc cacaattcca tcctatcagc cctgcaacag acacacaggc cgtgggacga
     2461 gttttctccc tacagcagga ttcaggtcgc catcccctgg actgttccgg ggcagtctga
     2521 tcagctcggc ttctaagagt tcagggaaac tgtctgagcc ttcacttccc atagaggatt
     2581 cccaggatct gtacaccgcc tccccagagc cgaagacact tttcctagga gcaggagact
     2641 tccagttctg tttggaagat gacactcaga gccaactgtt ggatgcagat ggatttttaa
     2701 acgttagaaa tcaccggaat cggtatcagg ctttgaagcc acagttgccg ctggccagta
     2761 tggacgagaa tgccatggat gccaacatgg atgagttgct cgacttgtgt accggacagt
     2821 tcacatctca gtctgaggag aaatgtcagc caaggaagaa tgaccagaaa gaaaacatgg
     2881 aggaacttct gaacctctgc tctggcaaat ttccttctca agacgcttcc ccggtggccc
     2941 cactggagct gaggacggag gagagggaga gtggcacaga agatcccatg gaggaggcgc
     3001 ttgctctttg ctcgggctcc ttcccaacag acagggagga agagggtgaa gaggaggaat
     3061 ttggagactt tcagcttgtt tcaaaggaga atgaatttgc tagcgatgag ggtggacaca
     3121 gtgactccag tgatgaagag ctggccctgg acctggagga tgatgaagaa gagctcctga
     3181 agcagtctga gaagatgaaa cggcaaatga gactgaagaa atacttggag gatgaggcag
     3241 aggtgtcagg cagtgacgtg ggaagtgaag acgagtatga cggggaagat atcgatgagt
     3301 acgaagaaga cgccattgat gaggtgctcc catccgacga ggagctggaa agtcagatca
     3361 agaaaataca catgaaaacc atgttggatg acgataagcg gcgactgcgg ctttatcaag
     3421 agaggtacct tgctgacggg gatctgcaca gtgacgggcc tggacgaaca agaaaattcc
     3481 gatggaaaca catagatgac acctcccaga tggatctgtt tcacagagac tctgatgacg
     3541 atcaggttga agaacagctt gacgagactg aagccaagtg gagaaaggag cgaattgaac
     3601 gagagcagtg gcttcgggaa caggctcagc aggggaaaat tgctgctgaa gaagaggacg
     3661 ttggagaaga cagtcagttt atgatgctag ccaagaaagt cacagccaag gcactgcaaa
     3721 agaatgccag tcgtgccgtg gctgttcagg aatcgaagtc tgtgctcagt aacccttttg
     3781 aaaccatcag agcgggaggt gctcaccagc tgaagacagg ctccctgcta aaccagccca
     3841 aagctgtgct tcaaaaactc gctaccctgt ctgacctcaa ccccagcgct ccccgaaact
     3901 caagaaactt tgtcttccat acactttctc ccaccaaggc agagacagca aagagttcat
     3961 ctaagcctca ggtgagaaga aggggaccat cgtcaatgat gtcaccgtcc cctaagcggc
     4021 tgaagacaaa tgatagcagt ccaggaccaa agcgaagcat cttcagatac ttggaaagct
     4081 aacaccatcc gggatgccag tgtctgtgga aagtactcaa agtaggtcca gcacggaggg
     4141 gtgggactgc tgtttctgcc gatgacctct ccttccctca gcaccaacac attacgagca
     4201 gagcttcccc ttctccccac cacacagctc tccacagcat tttctttcct agttattttt
     4261 tagtttggcc accagagttc ccagcatcga cttacagaat aattgaagtc tcacttcttc
     4321 cgttaagcac ttgacatttt cttcctagca gtttcctggg ttgacaccac tttcaagtag
     4381 aggtgttcgt tggaggaaga aagtgtggca ttatagaaaa ttacagaaag cactgaaagc
     4441 cagcactggg atgaggcctc cacagccacg caacctctaa cccagtaacc aggccaagaa
     4501 gcacagtcct gtccttctgt gtcttgtaag cttctagcct tgatctctga ttaaccttta
     4561 tcgcctttga aataaggacg taagctggta cctagttgag aaagaggctg tccctcactt
     4621 tctgcagtgt gggaggaaga taaaggttaa acccagtgtc catccgcact ggataatcaa
     4681 tggagaacag accttccctg ggactggagg agtctcaact aacagcattt gttggagagc
     4741 ctccctccct tctgcagaaa cccgaccact atttattgct gctctcgggc cgagtttctt
     4801 ggcctgacca tcagagacca ctttactact tcatcactaa tgttgggagc agaccagcag
     4861 aattagtaaa aacgttgcag agagccgcca ttagttgctt tcttccacca gccactgggc
     4921 tttcagaaac gtagaccaac tccctcccgt tgctgctttg caaaagccat tgcaggggag
     4981 aggtgggcga gtgtggaagc gagcgtggga ggctggggga ggccgtgtcc atcttttact
     5041 gagagacaga acgcagccca ttcaactgac gaaacgagga tggaggtttt ctgttgggtg
     5101 ctagggctct ttggttttgt ttttttctaa tcctcaggat aaggatactg acttggaccg
     5161 aacacacagt tgtacatttg taatcttgta atgggagaga tgtgtataaa gctgttttaa
     5221 tatgtatgta gttttcaata aatctcactg ccccgagggc agggtttgct gtcca
//
