LOCUS       NM_013139                482 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus colipase (Clps), mRNA.
ACCESSION   NM_013139
VERSION     NM_013139.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Benter,I.F., Benboubetra,M., Hollins,A.J., Yousif,M.H., Canatan,H.
            and Akhtar,S.
  TITLE     Early inhibition of EGFR signaling prevents diabetes-induced
            up-regulation of multiple gene pathways in the mesenteric
            vasculature
  JOURNAL   Vascul Pharmacol 51 (4), 236-245 (2009)
   PUBMED   19577003
REFERENCE   3  (bases 1 to 482)
  AUTHORS   Rippe,C., Erlanson-Albertsson,C. and Lindqvist,A.
  TITLE     Consequences of metabolic challenges on hypothalamic colipase and
            PLRP2 mRNA in rats
  JOURNAL   Brain Res 1185, 152-157 (2007)
   PUBMED   17936733
REFERENCE   4  (bases 1 to 482)
  AUTHORS   Lindner,I., Helwig,U., Rubin,D., Li,Y., Fisher,E., Boeing,H.,
            Mohlig,M., Spranger,J., Pfeiffer,A., Hampe,J., Schreiber,S.,
            Doring,F. and Schrezenmeir,J.
  TITLE     Putative association between a new polymorphism in exon 3
            (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes
            mellitus in two independent Caucasian study populations
  JOURNAL   Mol Nutr Food Res 49 (10), 972-976 (2005)
   PUBMED   16189801
REFERENCE   5  (bases 1 to 482)
  AUTHORS   Jennens,M.L. and Lowe,M.E.
  TITLE     Rat GP-3 is a pancreatic lipase with kinetic properties that differ
            from colipase-dependent pancreatic lipase
  JOURNAL   J Lipid Res 36 (11), 2374-2382 (1995)
   PUBMED   8656075
REFERENCE   6  (bases 1 to 482)
  AUTHORS   Payne,R.M., Sims,H.F., Jennens,M.L. and Lowe,M.E.
  TITLE     Rat pancreatic lipase and two related proteins: enzymatic
            properties and mRNA expression during development
  JOURNAL   Am J Physiol 266 (5 Pt 1), G914-G921 (1994)
   PUBMED   8203536
REFERENCE   7  (bases 1 to 482)
  AUTHORS   Wicker,C. and Puigserver,A.
  TITLE     Rat pancreatic colipase mRNA: nucleotide sequence of a cDNA clone
            and nutritional regulation by a lipidic diet
  JOURNAL   Biochem Biophys Res Commun 167 (1), 130-136 (1990)
   PUBMED   2129524
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Nov 26, 2020 this sequence version replaced NM_013139.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M58370.1, CF249190.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093048 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               JAXUCZ010000020.1  6624277-6624414     c
            139-261             JAXUCZ010000020.1  6622834-6622956     c
            262-482             JAXUCZ010000020.1  6622234-6622454     c
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..482
                     /gene="Clps"
                     /gene_synonym="COLQ"
                     /note="colipase"
                     /db_xref="GeneID:25680"
                     /db_xref="RGD:2363"
     exon            1..138
                     /gene="Clps"
                     /gene_synonym="COLQ"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..393
                     /gene="Clps"
                     /gene_synonym="COLQ"
                     /note="colipase, pancreatic"
                     /codon_start=1
                     /product="colipase precursor"
                     /protein_id="NP_037271.2"
                     /db_xref="GeneID:25680"
                     /db_xref="RGD:2363"
                     /translation="MKVLVALLVTLVAVAYAAPGPRGLFINLEDGEICVNSMQCKSRC
                     CQHDTILGIARCTHKAMENSECSPKTLYGIYYRCPCERGLTCEGDRSIIGAITNTNYG
                     VCLDSTRSKQ"
     exon            139..261
                     /gene="Clps"
                     /gene_synonym="COLQ"
                     /inference="alignment:Splign:2.1.0"
     exon            262..482
                     /gene="Clps"
                     /gene_synonym="COLQ"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccttctgcc atctgaactg ccagctccca tccaccccag ccgtaccagt caccatgaag
       61 gtccttgttg ctctgcttgt aaccctcgtt gccgtggcct atgcagctcc tggaccccgg
      121 ggtcttttta tcaacctgga ggacggtgag atctgcgtaa acagtatgca gtgtaagagc
      181 agatgctgcc aacatgacac catcctgggc atcgcccggt gcacacacaa ggccatggag
      241 aacagcgagt gctccccaaa gaccctctat gggatctact acaggtgtcc ctgtgagcgg
      301 ggcctgacct gtgaggggga caggagcatc attggcgcca tcaccaacac caactacggc
      361 gtctgcctcg actccacccg ctccaagcag tgagatcgtg cagtgagctg ggccacctct
      421 ccctttccct tcactcgccc catctgagtc acccattggc aattaaagcc cattgcaacc
      481 tt
//
