LOCUS       XM_039092379            9858 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus clock circadian regulator (Clock),
            transcript variant X12, mRNA.
ACCESSION   XM_039092379
VERSION     XM_039092379.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039092379.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9858
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..9858
                     /gene="Clock"
                     /note="clock circadian regulator; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 57
                     ESTs, 3 long SRA reads, 20 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 31 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:60447"
                     /db_xref="RGD:620271"
     CDS             562..3156
                     /gene="Clock"
                     /codon_start=1
                     /product="circadian locomoter output cycles protein kaput
                     isoform X1"
                     /protein_id="XP_038948307.1"
                     /db_xref="GeneID:60447"
                     /db_xref="RGD:620271"
                     /translation="MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEK
                     KRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKP
                     TFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPE
                     GEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGN
                     FKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEF
                     TSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKG
                     KSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIE
                     ESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSS
                     TPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIP
                     QGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMF
                     LQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQ
                     QTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSM
                     PQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPT
                     FATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQ
                     LTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLT
                     DPSKVQPQ"
ORIGIN      
        1 gctgcggagc cctgcgccca cgacgcatgc gccgggaggg agcgcaatca cggactgggc
       61 tggcggctac cggctggaga gaggaaatcc cggacggcga gagcgcgaag gaaatctggc
      121 cgccgccgcg cgcgcgctcc cgtgaacgaa aagcacaaga agaaactttt ataggcattg
      181 ttgatttgac tagggcaccg atatcccgaa ctcaccggaa aggccagctg acccttgaac
      241 ttgtagagat tttcttgtct ccatctccca tttcaccata agagcactgt gaatcatagt
      301 ccagatatgc cattgcaccc aacttcatgt gatttctggg gattcaaaca caggtcctca
      361 tacttgtgtg ggttctgatt gtcctaagaa gaaggcctta aggttcgtgg gttttggaga
      421 atccgttctg cagacacaga aagtgaaaag gaccaactgc ccaacggtgg catcaactgg
      481 accatcccac attaaccact aattaagaaa atacacatga gaagtacaaa tgtctaccac
      541 aagacgaaaa cataatgtgt tatgttgttt accgtaagct gtagtaaaat gagctcaatt
      601 gttgacagag atgacagtag tatttttgat ggattggtgg aagaagatga caaggacaaa
      661 gcaaaaagag tatctagaaa caaatcagaa aagaaacgta gagatcagtt caatgtactc
      721 attaaggaac tggggtctat gcttcctggt aatgctagaa agatggacaa gtctactgtt
      781 ctacagaaga gcattgattt tttacgcaaa cataaagaga tcactgcaca gtcagatgct
      841 agtgaaattc gacaggactg gaaacctaca ttccttagta atgaagagtt tacacaatta
      901 atgttagagg ctcttgatgg ttttttttta gcgatcatga cagatggaag tgtagtatat
      961 gtatctgaga cggtaacttc gttacttgaa cacttaccat ctgatcttgt ggatcaaagt
     1021 atatttaatt ttatcccaga gggagaacat tcagaggttt ataagatact atctactcac
     1081 ctgctggaaa gtgactcctt aacccccgag gacttaaaat caaaaaatca gttagaattc
     1141 tgttgtcaca tgcttcgagg aacaatagac ccaaaggagc catccaccta tgaatatgtg
     1201 agatttatag gaaattttaa atctttaaac agtgtatcaa cttcaacaca taatggtttc
     1261 gaaggaacta tacagcgcac acacaggcct tcttatgaag atagagtttg tttcgtagct
     1321 actgtcagat tagctacccc tcagttcatc aaggaaatgt gtactgttga agaaccgaat
     1381 gaagagttca catctagaca cagtttagaa tggaagtttc tatttctaga tcacagggcg
     1441 ccgccaatca taggctatct gccgtttgaa gtcctgggaa catcaggcta tgattactat
     1501 catgtggacg acctagaaag tctggcaaaa tgtcatgagc acttaatgca atatggaaaa
     1561 ggcaaatcat gttactatag gttcttgacc aaaggacagc agtggatttg gcttcagact
     1621 cattactata tcacttacca tcagtggaac tcaaggccag agttcatcgt ttgtactcac
     1681 actgtagtaa gttatgcaga agttagggct gaaagacggc gagaacttgg cattgaggag
     1741 tctcttcccg agacagctgc tgacaaaagc caagattctg ggtctgacaa tcgtataaac
     1801 acagtgagtc tcaaggaagc actggaaagg ttcgatcaca gcccaactcc ttctgcctcc
     1861 tccagaagct caagaaagtc ctcgcacaca gcagtctcag acccttcctc aacgccgaca
     1921 aagatcccca ctgatactag cactcctccc agaccgcacc tgccagctca tgagaagatg
     1981 acacagcgga ggtcatcctt cagtagtcag tccataaact cccagtcagt tggttcatca
     2041 ttaacacagc cagcgatgtc tcaagctgca aatttaccaa tcccacaagg catgtcacag
     2101 tttcagcttt cagctcagtt aggagccatg cagcatctca aagaccagct agagcagcgg
     2161 acacgcatga tagaagcaaa tattcatcgg cagcaagaag aactaaggaa aattcaagaa
     2221 caacttcaaa tggtccatgg tcaagggcta cagatgtttt tgcagcaatc aaaccctgga
     2281 ctgaattttg gttctgttca actttcctct ggaaattcca atatccagca actcacacct
     2341 ataaatatgc aaggccaagt tgtccctgtt aaccagattc agagtggggt gaatgctggc
     2401 catgtcagca caggccagca catgatccag cagcagactt tacaaagtac atcaactcag
     2461 cagagtcaac agagtgtaat gagtggacac agtcagccaa cgtctcttcc aaaccagacg
     2521 ccgagcactc tgacagcccc actgtacaat acgatggtga tctctcagcc tgcagctggg
     2581 agcatggtcc cgattccatc cagtatgccg cagaacagca cccagagtgc tacagtcacc
     2641 acgttcactc aggacagaca gataaggttt tctcaaggtc agcaacttgt gaccaaatta
     2701 gtgactgctc ctgtagcttg tggggccgtc atggtgccaa gtaccatgct tatgggtcag
     2761 gtagtgactg cctatcctac ctttgccaca caacagcagc aggcacaggc cttgtcagta
     2821 acacagcaac agcagcagca gcagcagcag cagcaacagc agcagcagca gcagccgcag
     2881 caggcgcagc cgcagcccca gtcacagcag agttcccagg accagccgca tccttcagtt
     2941 cagcagccag ctcagctgac ccagccacca caacagttct tacagacatc tcggttgctc
     3001 catgggaatc cttcgacaca gctcatcctc tccgctgcct ttccactaca acagagcact
     3061 ttccctcctt cgcaccacca gcaacaccag caacagcagc tccatcggca caggactgac
     3121 agcctgactg acccttccaa ggtccagcca cagtagcaca cgcttcctca gacactggag
     3181 aggaagggga tggccagaga gactcgctca gatggcatgc ggtcagaagt tcaacagttt
     3241 tgtgagggtc gtcttgagtg ctccagttcc ttgagtagtt ggtagggaaa tgctgcccgg
     3301 cgcttcagaa gtccattata taccagccag tgggaaatgg ttatagggac acagccaatt
     3361 ctgacagttt ctttgcccag gtattttttg atagaaagag tatattgcca aatgctaaca
     3421 agctatcaac catgatcttt actgagtcgg aaaagcacta acaatgttgg tagctttaag
     3481 tgggtctgtg cctgtatcaa atattataga ggacacacca ctgccagggg tttgcttcga
     3541 atgccatgaa gatagtccag tagttagtag tcccacccca aactcctccc cctgttccga
     3601 tagtgatgga accgtgatta cgttgagaat gttgtgcagg tttgaattct ctgtgtacag
     3661 atgctgtaag atgatgtatc gtgtgtctgg atggaggcga gaaagcagct ttgtgtgtgc
     3721 agcgtgccct ccctcacagg taccagtaca ttcattagac tcaccaccgt gtgcagactg
     3781 agaacagctc tcgtctcgtc tcgtttacaa cactgtggag ttgtagatct tctccagggc
     3841 acaagtcttc ctgtgcgtgc tctggttgtg atgtcacagt ttgttcatgt gctgctggga
     3901 atggattgtt tttaaggtta aattattcta catttccatt tattcagaaa tatcccttat
     3961 ttcattattt ttcaattatg cttgagagaa ttgcactgct ttattatttt agatggttgg
     4021 ttgagagttt gatctcatat tttgatatat ttcatagttg gaatatttat gtaaatggtt
     4081 ttcaacaagc ctgaaagtga tttcaagaat gtttcagtta taagagtaaa gtttgcacac
     4141 aaaacatttt aggcactttt ttaacattct cagaggtggg aattttaact tttaggattt
     4201 gttggaatct tttttattat ccttaaaaat ttcaatgctt cttttagtca gaaatgattc
     4261 agggttattt gagggggaaa aaaacccata gtgccttgat tttaattcag gtgataattc
     4321 gccatcttga attcatcgtc tggtttcagc agcagttttg aaaccttagt acatttttag
     4381 cagtgtgtgg tctcagtgtc actctcaagt ccccgtgagg acggctgagc ctcttggact
     4441 accccaacag caccacagaa ttattccctg gtcgcatctt cctttaaagc taagtgagtc
     4501 tttggagaat caccagtaaa tgcgtgctca gagagagggg gacacgttgt cttgaaccct
     4561 caccgcagca ctagaataat gtaactcaca ggcttttaaa catacattaa gatttcattt
     4621 ggcaatatcc ttctctacag gtaataaact ccaacaatgc tacatacatt ttaaaagcat
     4681 ttttttagat tttatggtac taataatgga tttttcaatg atgggacaaa agattgtaga
     4741 aaatagagta tgaagtgcta cagagaaagg gggtcgagtg tggcagatga gaattgacct
     4801 aaaagtgaag tgtgcgatac taaggctgct aaaagaggtg ttcagatacc caaggcacag
     4861 ttgctaggta agggcccggg agctcagagt ccctgtctgt cctcagtctc actctcatcc
     4921 tatgtctttg cttccctgtt cacctggctg caactgagtt agaaagtcag tgatgaaaag
     4981 taaacaacca aagaaaattg gtacctacct tctgcaaaag aagtgtggct agataccagt
     5041 cagtaactca catatcacag agtcctccta gctgacattc ttatggacac caggagtagt
     5101 tgtgagaata cgtgtttatg caggtgtgta cacacatgat gacgtcatgt aagtagagca
     5161 cccacattgc ttttctccct tccaaattgc cttcttctct tacgccattc catgtcatct
     5221 gagttgtgcc tcatttgtct ttttgcattg catagtgata agcatttagc tacaggagat
     5281 acaacacgct agttatgtaa ttcctgttgt tcttcaccat tcagcttcct gcttacgagt
     5341 cgcagttgat aaaggcgctc ctagctgctg acgttgctgt ccacaaggct gcacagcagt
     5401 tgtgtgcacg agctgccgct tagctcctta actcttggtt tctttggatg gcaaactgtc
     5461 tctgtctgct ccccacaaga ctgcagtatt ctgacaaaag ttcctcttct gcctgttcat
     5521 ttctgtagcc aaagctgact gaaaccccaa atctaaatca tgaaaagata ccaaatagaa
     5581 acacttctca gcttcttaga aactttacct tcccctgctc tatttcatgg ggattcaagt
     5641 ttttttgaaa attttgattc tgggcagcgc tttttagtta agaaactgtt agggtaaagg
     5701 ccacacaggt tctggttgtc ctgctgcagg ttccttgcct ggactgcttc tacatggggt
     5761 gacacaggat tagaacagga agcacaaagc tgctcttgag gctgccatca aaccagagcc
     5821 tcgatattga aaagtagtcc tcttttccac cttagaggct gcgtgggagg acagcaactg
     5881 tggcagtggg caggcttgca aatgagcact aaggccttcc caagctcaat cctagtcagg
     5941 gtagcattga gtgctgtgct ctgctgtcac tagacagggc ttaggcgtgt actaataaaa
     6001 gatgccagtg ctttgaatag tttgtgatag aagactccat gctaaccagc aagtgtttga
     6061 attctgtgtg ctgtgtagtt ggtccttgcc ttaaagcagt ctcttggaag ttaggagcac
     6121 tggggcagtc cagccatatg tgggcatcat gttgagggag atgagccttg ttcaagcctt
     6181 agaaaggacc cttagtctac acaggtagat tcttttcact tgggtattac tgtgtttaaa
     6241 atgtgtccac tatgttgagg caatttaagt ggaacacaga tagcattttt agtatttctt
     6301 ttttctgttt ctttggtgat taaaggtttg ttggtaaaca tttgtgtaaa agttgttcaa
     6361 gcctctcatc tttccagtac ctgtggtcct gttgttagaa ccagaatcca cgatggaaag
     6421 tataaacact ggatattaac attgctgagg gcgcatagcc aggagcgagc tgactgcaac
     6481 ttctcagtgg tgaagaaaca gcacaacacg gcacttgcca ttttcatagt gattgcatag
     6541 agaccttcta agattgtctg gattgagtga atactcttct aagaggagct tctcaagtaa
     6601 atgcaaagga aaagagttga ctatttttat agcatattta atatatttgt atatatctat
     6661 gagtgtagta ggaacccttc acaggcctcc cacttttcta atcccctccc cttttaccat
     6721 agcctagtac agcctcatcc gcatgggtaa tgtgcctatc gtcagcctac ctaccaaaag
     6781 atagtgctgc tgctttctga gacaggtgag atcagactct catgcctggg gatcctttat
     6841 gggaggaata gcacacttag aacaacacac cacagtttaa aagcatcatt ttgaaaggta
     6901 ataagcactt tattgcaatt attcatttag ataaagtttg tatcttaggc attaaccatt
     6961 tttaaaggat cccctaatca tcacttaggt gaaattataa atgacacatt tctgagaaat
     7021 gtttagatcc agtgaaccgt agcaggttta tgggagtgat ttcaaggtag ccaaataaac
     7081 tcggacttct gttttgaatg tggtggagtc aggagattgt agttgcgtag tttgatttaa
     7141 acactattgt aaacctatct tgcctattgt gtggacacca aaagagacca atgagcctgt
     7201 ttattttcag aggtctagga atatgcatct gtctgagtag atatacagaa ctaatctata
     7261 aacggttggt agtaatattt taggatacag taatttcaag aattattgag tgttttaaat
     7321 gtgccctgaa atgttggcat gtcatttcag cgttcccatt tgagttgctc ttgtaatatt
     7381 tttgcacaaa aaggactgag aacaagactg ctttggttga agaaaactat aatttggtct
     7441 tattttaatg tctcctgtgg aaacactgga ggtaaattgg ttggcatagt tactaattca
     7501 ggatatttaa aacagtgttg aacagctcat cagaaattaa gcaaacttat atatttaaaa
     7561 attaaaattc tttttttcca cgtgactgtt ttgcatattt tttccgttgt cataccacta
     7621 cattccttgt ttttctgata taatactttg taaaacattc aagtattcaa caggactttg
     7681 taagatgcct gggttctccc aggaagacgt cctagtgaac tgagttatag ttgtacagtc
     7741 tgtgaagact gttgagattc catcaccacc accagcaaac actgaggtgc tgagctaagc
     7801 gacaatcacc attgtaagta tttacaggac gtaggagagg ctgcgggaac acttgttccc
     7861 aaagcagttc tctgggtttc ttacataaaa tggccatgta tttgtatctc tacattgtct
     7921 agttagtgat ttggtttcct gtatttagtt tattgcatca ttatcttgtt cttggagaac
     7981 tggctcttgt ttggggcagt cactacaccc caccctccag tgactctcca ctgacagctc
     8041 attggggtcc attgtacgtc gatggtggtg cgggtgtact tccctcctgc tctgaactca
     8101 tttgaggaaa gaacattaaa agctagcttc tttcagccct gctcgcacta ctcagccttt
     8161 tctagtgtca cttgttgcct tccctgattc atgggcactt tttatacggt tgttccccca
     8221 atagtcaaag gccagtatga cagaaccaag ggcatatgtt gcctgttttt gcccatttgg
     8281 ggaaatgcta gcaaagtaat atctattaat ggctgccagt catccttata tccatacata
     8341 aatgtcctta tatatatagt ttaacaatca atgtatgcac actgaaaact ttgaaaagtt
     8401 ggctatcttt agatcctcca tagtccagca aagtggtgct taaacatggg aagccgagct
     8461 gaggggctcc ttcctgctca cacacactgg gaaatgacct ccttcagcac taccgtggct
     8521 ctggagcccc acaggcagag tctagcacac acccctggag gacagttacg aaaatactgt
     8581 cagacacaaa atgggtttaa tgacctttaa ggcatttaac tctgaggggg gtaaattcaa
     8641 aatataccat tttttgatgt ttggttttaa atctgagaaa acaaactgtg acatcgcttt
     8701 aagaaatgac atccaaatgt tttatgtttg agttggcctg tactggttca catttattgc
     8761 tggcaatggt tttaagagta ttacaaagct aatatacaga ggaaactgtt aagttgtata
     8821 actagacaat cagcttcaag caaagacatt gccttcaaaa agtccattat taagcaatgg
     8881 gtgtgtcagc cagaactgga atttatacct ttctaaaatg attttaaatc tattttcctg
     8941 tggtttaagt tggggaaagc tccagtatag cactttcata tttaccctgt gtaaagatta
     9001 aagcccaaag acaaattagt gctgtattaa aaccagttag tgcaaaaaaa aaatatatgt
     9061 tttatctttg taaagtttaa ttgttaaatt ggttagtagt tgtacaaaca tgcaccaggt
     9121 ttttctaagt tccgtgtgtc ttgctgtgct gttcttgaca ttgctgtcct tactgcttgg
     9181 ttctgggttt aaactgaaac aataatagac agagcccatc gtttctggct gccgatctcg
     9241 gataagcatt cttcccctcc taagcaaaca tgtgattgaa ataagcttaa ttcatagaac
     9301 tgagactgac gttctttcag gtatcaccac tttgccaaaa ccagaactat gaaggattag
     9361 gaatggtttc aatggtgcta cattaggttc cctggttttc ataagctacg tttggaaata
     9421 cagtattgaa taaaatgtag actcttgtta acagctgaat attgccattt taattgggtc
     9481 caatataatt ggttattctt atcaaagtta acctttggag aagtaaaact gttacatcag
     9541 cacgcctcac tcaggcttat gctgcatgac gggcacagct ctaacttagt ctcaacatgc
     9601 catctaacac tctcttctct agaccttcga gtgtattcag aacctaaagc tacagcagaa
     9661 gagccaagca gtagcaatgt ttgttttatt tatttttttt gtaaatgtaa aaataactag
     9721 atccagacct gtttcctttg atttaaaata aagaatacct cagtgctgct tctcagaatc
     9781 acctgcttca tgtggcacat aatgtgtaag agtcccattt ggatttacaa agactattaa
     9841 atgtttttaa atctgtca
//
