LOCUS       NM_001107501            2123 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus CAP-GLY domain containing linker protein 3
            (Clip3), mRNA.
ACCESSION   NM_001107501 XM_001078996 XM_218481
VERSION     NM_001107501.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Chen X, Chen C, Hao J, Zhang J and Zhang F.
  TITLE     Effect of CLIP3 Upregulation on Astrocyte Proliferation and
            Subsequent Glial Scar Formation in the Rat Spinal Cord via STAT3
            Pathway After Injury
  JOURNAL   J Mol Neurosci 64 (1), 117-128 (2018)
   PUBMED   29218499
  REMARK    GeneRIF: CLIP3 up-regulation following spinal cord injury is
            associated with astrocyte proliferation.  CLIP3 interacted with
            STAT3 in the injured spinal cord.
REFERENCE   2  (bases 1 to 2123)
  AUTHORS   Deng X, Wei H, Lou D, Sun B, Chen H, Zhang Y and Wang Y.
  TITLE     Changes in CLIP3 expression after sciatic nerve injury in adult
            rats
  JOURNAL   J Mol Histol 43 (6), 669-679 (2012)
   PUBMED   23014974
  REMARK    GeneRIF: CLIP3 and PCNA expression during early myelination may be
            related to the direct uptake and transport of lipids and
            cholesterol, by Schwann cells to prepare for the formation of
            myelin sheath-like structures around regenerated axons after SNI.
REFERENCE   3  (bases 1 to 2123)
  AUTHORS   Sorice M, Matarrese P, Manganelli V, Tinari A, Giammarioli AM,
            Mattei V, Misasi R, Garofalo T and Malorni W.
  TITLE     Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis
            triggered by CD95/Fas
  JOURNAL   PLoS One 5 (1), e8567 (2010)
   PUBMED   20052288
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2123)
  AUTHORS   Ding J and Du K.
  TITLE     ClipR-59 interacts with Akt and regulates Akt cellular
            compartmentalization
  JOURNAL   Mol Cell Biol 29 (6), 1459-1471 (2009)
   PUBMED   19139280
REFERENCE   5  (bases 1 to 2123)
  AUTHORS   Lallemand-Breitenbach V, Quesnoit M, Braun V, El Marjou A, Pous C,
            Goud B and Perez F.
  TITLE     CLIPR-59 is a lipid raft-associated protein containing a
            cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that
            perturbs microtubule dynamics
  JOURNAL   J Biol Chem 279 (39), 41168-41178 (2004)
   PUBMED   15262990
REFERENCE   6  (bases 1 to 2123)
  AUTHORS   Perez F, Pernet-Gallay K, Nizak C, Goodson HV, Kreis TE and Goud B.
  TITLE     CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein
            belonging to the CLIP-170 family
  JOURNAL   J Cell Biol 156 (4), 631-642 (2002)
   PUBMED   11854307
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_218481.4, XM_001078996.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2123
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /note="CAP-GLY domain containing linker protein 3"
                     /db_xref="GeneID:308493"
                     /db_xref="RGD:1306245"
     exon            1..136
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            137..358
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1836
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /codon_start=1
                     /product="CAP-Gly domain-containing linker protein 3"
                     /protein_id="NP_001100971.1"
                     /db_xref="GeneID:308493"
                     /db_xref="RGD:1306245"
                     /translation="MTKTDPAPMAPPPRGEEEEEEEEDEPVPEAPSPTQERRQKPVVH
                     PSAPAPLPKDYAFTFFDPNDPACQEILFDPKTTIPELFAIVRQWVPQVQHKIDVIGNE
                     ILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWT
                     NMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASNLCLGAAKCLL
                     EHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCTLPKVT
                     LPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGK
                     NDGSVGGVRYFICPPKQGLFASVSKVSKAVDAPPSSVTSTPRTPRMDFSRVTGKGRRE
                     HKGKKKSPSSPSLGSLQQREGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIEL
                     DQPTGKHDGSVFGVRYFTCAPRHGVFAPASRIQRIGGSTDPPGDSVGAKKVHQVTMTQ
                     PKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS"
     exon            359..498
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            499..592
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            593..754
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            755..873
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1110
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1246
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1375
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1519
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1643
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1708
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1781
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..2123
                     /gene="Clip3"
                     /gene_synonym="RGD1306245"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccccgcctct gtctgggcct cgtccccttc tctctgtctc cctctcgtcc cccccattcg
       61 tcccctgaca ccgacacccc gatactcctg cactctcttc agtctcagcc tagctctcca
      121 atccgcgcta tccgaggttt gcctccaggc cacccccaac tttgcaccgg cccccaaggg
      181 ctactgagga ccatgactaa gacggatcct gccccaatgg cccctccacc ccgaggggag
      241 gaggaagagg aggaggagga agatgaaccg gtcccagaag cccccagccc cacccaggag
      301 cgccggcaaa agccagttgt gcacccctca gcacctgctc cgctccccaa agactacgct
      361 tttaccttct tcgaccccaa tgaccctgcg tgccaggaga ttctctttga tccgaagacc
      421 accatcccag agctgtttgc catcgtacgc cagtgggttc cccaagtcca gcacaagata
      481 gacgtcattg gcaatgagat tctgcgtcgg ggctgccatg tgaatgatcg tgacggcctc
      541 acagatatga cactgctcca ttatgcgtgc aaggctgggg cccatggagt tggagaccct
      601 gcggccgctg tgcgcctctc gcagcagctg ctggcgctag gcgcagatgt gactctgcgc
      661 agccgctgga ccaacatgaa cgcacttcac tatgcggcct atttcgacgt gccagacctt
      721 gtgcgtgtgc tgctgaaagg ggcgaggccc agggtggtga actccacctg tagtgacttc
      781 aaccatggct cagctctgca catcgctgcc tcgaatctgt gcctgggcgc cgccaaatgt
      841 ttactggagc atggtgccaa cccagcgctg aggaatcgaa aaggacaggt accagcggaa
      901 gtggtcccag accccatgga catgtccctt gacaaggcag aggcagccct ggtggccaag
      961 gaactgcgga cgctgctaga agaggctgtg ccactgtcct gcacccttcc taaagtcaca
     1021 ctacccaact atgacaacgt cccaggcaat ctcatgctca gcgcgctggg cctgcgtcta
     1081 ggagaccgag tgctcctcga tggccagaag acgggcacgc tgaggttctg cgggaccacc
     1141 gagttcgcca gtggccagtg ggtgggcgtg gagctagatg aaccggaagg caagaacgac
     1201 ggcagcgttg ggggtgtccg gtacttcatc tgccctccca agcagggtct ctttgcatct
     1261 gtgtccaagg tctccaaggc agtggatgca cccccctcat ctgttacctc cacgccccgc
     1321 actccccgga tggacttctc ccgtgtaacg ggcaaaggcc ggagggaaca caaagggaag
     1381 aagaagtccc catcttcccc atctctgggc agcctgcagc agcgtgaagg ggccaaagct
     1441 gaagttggag accaagtcct tgtggcaggc cagaagcagg ggattgtgcg tttctatggg
     1501 aagacggact ttgctccagg ttactggtat ggcattgagc tggaccagcc cacgggcaag
     1561 catgacggct ctgtgttcgg tgtccggtac tttacctgtg ccccgaggca cggggtcttt
     1621 gcaccagcat ctcgtatcca gaggattggt ggatccactg atccccctgg agacagtgtt
     1681 ggagcaaaaa aagtgcatca agtgacaatg acacagccca aacgcacctt cacaacagtc
     1741 cggaccccaa aggacattgc atcagagaac tctatctcca ggttactctt ctgctgctgg
     1801 tttccttgga tgctgagggc ggagatgcag tcttagagac ctggatacct aacacagaga
     1861 cagagtcccc tctagcatct cctgacacaa ggagacccca gtcaccctaa gatagagatt
     1921 cccagtgaca cctccagaat agaaaccccg ttagccagcc ctcgattact gaggtcccat
     1981 tattaacaga tctcccatga cgactccccc aaatacagac ctcatgttac cccaaaagag
     2041 attccctgag tagcaccttc aggctagtcc ctgtccccta cccctcagag cagatttccc
     2101 ccaataaaca ttttccacat cac
//
