LOCUS       NM_176078               2527 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Rattus norvegicus chloride intracellular channel 6 (Clic6), mRNA.
ACCESSION   NM_176078
VERSION     NM_176078.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2527)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 2527)
  AUTHORS   Griffon,N., Jeanneteau,F., Prieur,F., Diaz,J. and Sokoloff,P.
  TITLE     CLIC6, a member of the intracellular chloride channel family,
            interacts with dopamine D(2)-like receptors
  JOURNAL   Brain Res Mol Brain Res 117 (1), 47-57 (2003)
   PUBMED   14499480
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Dec 3, 2020 this sequence version replaced NM_176078.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY191249.1, SRR26643299.47497.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1435              JAXUCZ010000011.1  45223715-45225149
            1436-1545           JAXUCZ010000011.1  45254941-45255050
            1546-1671           JAXUCZ010000011.1  45255567-45255692
            1672-1778           JAXUCZ010000011.1  45257005-45257111
            1779-1960           JAXUCZ010000011.1  45257788-45257969
            1961-2527           JAXUCZ010000011.1  45265695-45266261
FEATURES             Location/Qualifiers
     source          1..2527
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..2527
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /note="chloride intracellular channel 6"
                     /db_xref="GeneID:304081"
                     /db_xref="RGD:727938"
     exon            1..1435
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..2122
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /note="intracellular chloride channel 6b;
                     glutaredoxin-like oxidoreductase CLIC6"
                     /codon_start=1
                     /product="chloride intracellular channel protein 6"
                     /protein_id="NP_788267.2"
                     /db_xref="GeneID:304081"
                     /db_xref="RGD:727938"
                     /translation="MAEATEPKEVSSGSQGQPEGAVIEGPGEPGAADLEGREASEGAA
                     EAPRDLGEGAEAMASGKEEGGCGQDGEIGEVQAQDPRPGPGTETPGTSGAPGEAEAAE
                     CDSEGALIPQGAEEAPSAQQVQGTSSGLDAQGEAPEVPEDARREPEDPKASEAGEEAE
                     SGQEALGGSAPESQINPEVQGPVGDNMDTEAPAGEPQGSEGEPQGGGESSPQPQDEAI
                     EIAAAEVGGHEPGELAGASAADAKGEGETLRKDGFEEAAPEEARVDSGENGFEEAAPE
                     EARVDSGENRDQGRLQEETGEEEARPESGLKGPCEEAIQEKAPDGSLDGEEAKSTGHE
                     ESQVELSNHLAEETSAQGGEELGRVNGRRENGPASEEGDLGQEHDITLFVKAGSDGES
                     IGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVN
                     KIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANDIYEKNLLRA
                     LKKLDSYLNSPLPDEIDAYSTEDVTVSQRKFLDGDELTLADCNLLPKLHIIKIVAKKY
                     RGFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDAAKRMK"
     exon            1436..1545
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1671
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1778
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1779..1960
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2527
                     /gene="Clic6"
                     /gene_synonym="Clic6b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttcgaaaga gttgagaggc aagctgagtt ctttagcccc acaccccaga ctgagcataa
       61 ggattggggt ccgggtgcga atttagaaga agcacgaacg cttgaggaag agcccaaaga
      121 ccttaagtca gggaaaaggg acatagagtc ttggggccct ctggatttcg catcaagcga
      181 aacctttgct tccagagccc agagtgcggt gtcctctcgg aggaggcacg gcagcccctg
      241 cccctcaccc ctgagcggcg tcgaggaagg gtgttttatc atggctgagg ccacggagcc
      301 caaggaggtc tcttcgggtt cccaagggca accagaaggt gcggtgatcg agggaccagg
      361 agagcctggg gctgcggacc tggaggggcg ggaagcgagc gagggagctg cagaggcacc
      421 cagggacctg ggggagggcg cggaggccat ggcctcaggg aaggaggaag gaggctgtgg
      481 gcaggatggg gaaatcgggg aagtgcaggc gcaggacccg cgcccgggcc ccgggacgga
      541 gacaccgggc accagtggag ctccgggtga agcggaggct gcggaatgcg actccgaggg
      601 cgccttgatc ccgcagggag cggaggaggc gccaagcgcc cagcaggtgc agggaacgag
      661 ctcggggcta gacgctcagg gtgaggcccc tgaggtcccc gaggacgctc gccgggagcc
      721 agaggacccc aaggcttcag aggcagggga agaggcagaa tctggtcagg aagctctggg
      781 aggcagcgcg ccagagtcgc agatcaatcc agaagtccag ggacctgtag gggacaacat
      841 ggacacagag gcccccgcag gagagccaca ggggtcagag ggagagcccc agggtggagg
      901 ggaaagcagc cctcagcccc aggatgaggc gattgagatt gcagccgcag aggttggagg
      961 gcacgagccc ggggagctgg cgggcgcttc agccgcagac gccaaggggg aaggggaaac
     1021 cctgaggaaa gatgggttcg aggaagctgc tcccgaggag gcaagagtag actctggcga
     1081 gaatgggttc gaggaagcag ctcccgagga ggcaagagta gactctggag agaataggga
     1141 ccagggcagg ctccaggagg agaccgggga ggaagaagcg agaccggaat ccgggttgaa
     1201 gggaccctgc gaggaggcca tccaagagaa ggcccccgac ggcagccttg atggagagga
     1261 ggccaaatcc accgggcacg aggagtcgca agtggagctc agtaaccacc tagcggagga
     1321 gaccagcgcc cagggcggag aagagttggg gcgagtgaat ggacgtaggg agaacggccc
     1381 agcttcggag gagggggatc tgggacagga gcacgacatc accctctttg tcaaggctgg
     1441 ctctgatgga gagagcatcg gaaactgccc attctcacag cgtctcttta tgatcctctg
     1501 gctaaagggt gttatattca atgtgacaac ggtggacctg aaacggaagc ctgcagacct
     1561 gcagaacctg gctcctggga ccaaccctcc tttcatgact tttgatggtg aagtcaagac
     1621 agatgtgaat aagattgagg agttcttaga ggagaagtta gtccccccga ggtaccctaa
     1681 gctgggaacc caacaccccg aatccaactc agcgggaaat gacgtttttg ccaaattctc
     1741 agcgtttatt aagaacacca agaaggatgc aaatgacatt tatgaaaaga acctactacg
     1801 ggccctgaag aagctggaca gttacttaaa cagcccgctg ccagacgaaa tagatgccta
     1861 cagtacggag gatgtcactg tttcccagag gaagtttctg gatggggatg agctcacact
     1921 ggccgactgt aacctcttac ccaagcttca catcattaag attgtggcca agaaatacag
     1981 aggttttgag tttccttctg aaatgactgg catttggagg tacttgaaca atgcttatgc
     2041 ccgggatgag ttcactaaca cgtgtccagc tgaccaggag attgaacacg cgtattcaga
     2101 cgcagcgaaa aggatgaagt aatgctggct tgcgtctttc ctcagatgag tgaacagggc
     2161 ttccaggagg accttctatg tttcttcccc aaaacagctt ttgcaaaaag aacgctgact
     2221 ctctaaatgc caccgcagga tgcatggtct tgcgatttgt ctgctccatc tcatctacgc
     2281 taatttatat ctttgagatt cagtcctctg gtcggccatg tttagggaaa tagtgttttg
     2341 tagcttgttt cagagcaaac tggctttgac tcaagttctc accattttta agaggttagt
     2401 ctttgatagt tgtgataatc acatgactcc cttttctctt cttaaatatc agtttaaaat
     2461 ggaaatgccg gtttagactt atagaatact ttagaacagt attagagggt atgaagaaga
     2521 agttaaa
//
