LOCUS       NM_053753               1888 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus C-type lectin domain family 4, member F (Clec4f),
            mRNA.
ACCESSION   NM_053753
VERSION     NM_053753.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Pridans,C., Irvine,K.M., Davis,G.M., Lefevre,L., Bush,S.J. and
            Hume,D.A.
  TITLE     Transcriptomic Analysis of Rat Macrophages
  JOURNAL   Front Immunol 11, 594594 (2021)
   PUBMED   33633725
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  AUTHORS   Yang,C.Y., Chen,J.B., Tsai,T.F., Tsai,Y.C., Tsai,C.Y., Liang,P.H.,
            Hsu,T.L., Wu,C.Y., Netea,M.G., Wong,C.H. and Hsieh,S.L.
  TITLE     CLEC4F is an inducible C-type lectin in F4/80-positive cells and is
            involved in alpha-galactosylceramide presentation in liver
  JOURNAL   PLoS One 8 (6), e65070 (2013)
   PUBMED   23762286
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1888)
  AUTHORS   Fadden,A.J., Holt,O.J. and Drickamer,K.
  TITLE     Molecular characterization of the rat Kupffer cell glycoprotein
            receptor
  JOURNAL   Glycobiology 13 (7), 529-537 (2003)
   PUBMED   12672702
  REMARK    GeneRIF: The receptor displays monosaccharide-binding
            characteristics similar to the hepatic asialoglycoprotein receptor,
            but with somewhat less selectivity
REFERENCE   4  (bases 1 to 1888)
  AUTHORS   Hoyle,G.W. and Hill,R.L.
  TITLE     Structure of the gene for a carbohydrate-binding receptor unique to
            rat kupffer cells
  JOURNAL   J Biol Chem 266 (3), 1850-1857 (1991)
   PUBMED   1846367
REFERENCE   5  (bases 1 to 1888)
  AUTHORS   Hoyle,G.W. and Hill,R.L.
  TITLE     Molecular cloning and sequencing of a cDNA for a carbohydrate
            binding receptor unique to rat Kupffer cells
  JOURNAL   J Biol Chem 263 (16), 7487-7492 (1988)
   PUBMED   2836387
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M55532.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J03734.1, BC098661.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1888
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /note="C-type lectin domain family 4, member F"
                     /db_xref="GeneID:114598"
                     /db_xref="RGD:621062"
     exon            1..127
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1704
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /note="C-type lectin 13; C-type lectin superfamily member
                     13; Kupffer cell receptor; C-type (calcium dependent,
                     carbohydrate recognition domain) lectin, superfamily
                     member 13"
                     /codon_start=1
                     /product="C-type lectin domain family 4 member F"
                     /protein_id="NP_446205.1"
                     /db_xref="GeneID:114598"
                     /db_xref="RGD:621062"
                     /translation="MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQ
                     AIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGSDNCSQFVRRAE
                     MQEAIQSLRASGNSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKG
                     TGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLG
                     RGLEEAQSEIQALRGSLQSSNDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTS
                     LKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSRELQ
                     TLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQ
                     KAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASV
                     TSQEEQAFLVQITNAVDHWIGLTDQGTEGNWRWVDGTPFDYVQSRRFWRKGQPDNWRH
                     GNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS"
     exon            128..244
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     exon            245..328
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     exon            329..1267
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1419
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1538
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1888
                     /gene="Clec4f"
                     /gene_synonym="Clecsf13; Kclr"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggctccca ggacagacct tagaatcgtg gggcaagagc agtgcaggag gatgaaggag
       61 gcggaactga acagagatgt ggctaaattc tgcactgaca accagtgtgt catcctacag
      121 ccccaaggac tggggcctaa gtcagctgct cccatggctc ccaggacact gaggcacgtc
      181 caggccattg tggcactagt ggtggtgact gtgttcttct ctctccttgc tctttttgtg
      241 gtggttttac agccttggag acagaagcag aatgaggatc atcctgtcaa agccgggctt
      301 catggaggca actactctgg atctgacaat tgttcccaat ttgtccggag ggcagaaatg
      361 caagaggcta tccagagtct cagggcctct gggaattcta gcagctgtca caaggagata
      421 cagaccctga agtaccagat ggacaatgtt agttctcagg tgcagttgct tgggggccat
      481 ctggaggaag ccaatgctga catccagcag gcaaaggatg tgctgaaggg cactggggcc
      541 ttggcctcgg agacccaggc actgagaagc tccttggagg tcgccagtgc ggatatccat
      601 agtctgagag gcgatttgga aaaggcaaat gccatgactt cccagaccca aggtctctta
      661 aagagcagca cagacaacac cagtgctgag ctccatgtgc tgggcagagg cctggaggaa
      721 gcccagtctg agatccaggc tttgagggga agtctgcaga gttcaaatga cctcggctcc
      781 cggactcaga actttctcca gcacagtatg gacaacatta gtgctgaaat ccaggccatg
      841 agagatggta tgcaaagagc tggcgaggag atgacctcat taaagaaaga tctagaaaca
      901 cttactgctc agattcaaaa tgcaaatggc cacctggagc agacagatac ccagatccag
      961 gggctaaaag ctcagttgaa aagcaccagt tccttgaact cccagattga ggtggtcaat
     1021 ggcaaattga aagactccag cagagagtta cagacactga gaagggacct gagtgatgtc
     1081 tcagctttga agtccaacgt ccagatgtta cagagcaatc ttcagaaggc caaggcagag
     1141 gtacagagtt tgaaaacagg tctggaggct accaaaactc tcgctgccaa gattcaggga
     1201 caacagagtg acctggaggc cctgcagaaa gctgtggctg cacacacgca ggggcagaag
     1261 actcagaatc aggttctcca gctgatcatg caggactgga agtacttcaa tggaaagttt
     1321 tattactttt ctcgtgacaa gaagtcatgg catgaggccg agaatttctg tgtgtcccag
     1381 ggagcacacc tggcttcggt gacctctcag gaggagcagg cattcctggt acagatcaca
     1441 aatgctgtgg accattggat tgggctcact gatcagggca cagagggcaa ctggcgctgg
     1501 gtggatggga caccattcga ttatgtccag agcagaaggt tttggaggaa aggccagcct
     1561 gacaactgga gacacggaaa cggagagcgt gaagactgtg ttcatctgca gcggatgtgg
     1621 aacgacatgg cctgtgggac cgcctacaac tgggtgtgca agaagtctac agattggtct
     1681 gtggccagaa cggaccagag ctgagtctct cccccctgag actcctatag ccttgaactc
     1741 tcctcaggac ttcttgtgtc ctgtgttgcc attgtctcgc catttaaaac atgcttgcct
     1801 ccttaaagat aagccctgca tgctagtgtc cccttagtgc cccaacaggt ctgcctagat
     1861 aagccctcaa taaacactca ttgaatgg
//
