LOCUS       NM_001398638             980 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus C-type lectin domain family 3, member B (Clec3b),
            mRNA.
ACCESSION   NM_001398638 XM_003750609
VERSION     NM_001398638.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 980)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   2  (bases 1 to 980)
  AUTHORS   Didangelos,A., Yin,X., Mandal,K., Baumert,M., Jahangiri,M. and
            Mayr,M.
  TITLE     Proteomics characterization of extracellular space components in
            the human aorta
  JOURNAL   Mol Cell Proteomics 9 (9), 2048-2062 (2010)
   PUBMED   20551380
REFERENCE   3  (bases 1 to 980)
  AUTHORS   Cartwright,M.J., Schlauch,K., Lenburg,M.E., Tchkonia,T.,
            Pirtskhalava,T., Cartwright,A., Thomou,T. and Kirkland,J.L.
  TITLE     Aging, depot origin, and preadipocyte gene expression
  JOURNAL   J Gerontol A Biol Sci Med Sci 65 (3), 242-251 (2010)
   PUBMED   20106964
  REMARK    GeneRIF: age-related changes in preadipocyte gene expression differ
            among depots, potentially contributing to fat redistribution and
            dysfunction.
REFERENCE   4  (bases 1 to 980)
  AUTHORS   Stoevring,B., Jaliashvili,I., Thougaard,A.V., Ensinger,C.,
            Hogdall,C.K., Rasmussen,L.S., Sellebjerg,F. and Christiansen,M.
  TITLE     Tetranectin in cerebrospinal fluid: biochemical characterisation
            and evidence of intrathecal synthesis or selective uptake into CSF
  JOURNAL   Clin Chim Acta 359 (1-2), 65-71 (2005)
   PUBMED   15901484
REFERENCE   5  (bases 1 to 980)
  AUTHORS   Hermann,M., Pirkebner,D., Draxl,A., Margreiter,R. and Hengster,P.
  TITLE     In the search of potential human islet stem cells: is tetranectin
            showing us the way?
  JOURNAL   Transplant Proc 37 (2), 1322-1325 (2005)
   PUBMED   15848710
REFERENCE   6  (bases 1 to 980)
  AUTHORS   Iba,K., Durkin,M.E., Johnsen,L., Hunziker,E., Damgaard-Pedersen,K.,
            Zhang,H., Engvall,E., Albrechtsen,R. and Wewer,U.M.
  TITLE     Mice with a targeted deletion of the tetranectin gene exhibit a
            spinal deformity
  JOURNAL   Mol Cell Biol 21 (22), 7817-7825 (2001)
   PUBMED   11604516
REFERENCE   7  (bases 1 to 980)
  AUTHORS   Lorentsen,R.H., Graversen,J.H., Caterer,N.R., Thogersen,H.C. and
            Etzerodt,M.
  TITLE     The heparin-binding site in tetranectin is located in the
            N-terminal region and binding does not involve the carbohydrate
            recognition domain
  JOURNAL   Biochem J 347 Pt 1 (Pt 1), 83-87 (2000)
   PUBMED   10727405
REFERENCE   8  (bases 1 to 980)
  AUTHORS   Graversen,J.H., Lorentsen,R.H., Jacobsen,C., Moestrup,S.K.,
            Sigurskjold,B.W., Thogersen,H.C. and Etzerodt,M.
  TITLE     The plasminogen binding site of the C-type lectin tetranectin is
            located in the carbohydrate recognition domain, and binding is
            sensitive to both calcium and lysine
  JOURNAL   J Biol Chem 273 (44), 29241-29246 (1998)
   PUBMED   9786936
REFERENCE   9  (bases 1 to 980)
  AUTHORS   Iba,K., Sawada,N., Chiba,H., Wewer,U.M., Ishii,S. and Mori,M.
  TITLE     Transforming growth factor-beta 1 downregulates
            dexamethasone-induced tetranectin gene expression during the in
            vitro mineralization of the human osteoblastic cell line SV-HFO
  JOURNAL   FEBS Lett 373 (1), 1-4 (1995)
   PUBMED   7589422
REFERENCE   10 (bases 1 to 980)
  AUTHORS   Wewer,U.M., Ibaraki,K., Schjorring,P., Durkin,M.E., Young,M.F. and
            Albrechtsen,R.
  TITLE     A potential role for tetranectin in mineralization during
            osteogenesis
  JOURNAL   J Cell Biol 127 (6 Pt 1), 1767-1775 (1994)
   PUBMED   7798325
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Dec 21, 2021 this sequence version replaced XM_003750609.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ234406.1, FM046490.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               JAXUCZ010000008.1  131687575-131687780
            207-305             JAXUCZ010000008.1  131690973-131691071
            306-980             JAXUCZ010000008.1  131692618-131693292
FEATURES             Location/Qualifiers
     source          1..980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..980
                     /gene="Clec3b"
                     /gene_synonym="Tna"
                     /note="C-type lectin domain family 3, member B"
                     /db_xref="GeneID:100912012"
                     /db_xref="RGD:1311031"
     exon            1..206
                     /gene="Clec3b"
                     /gene_synonym="Tna"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..706
                     /gene="Clec3b"
                     /gene_synonym="Tna"
                     /note="tetranectin-like; tetranectin (plasminogen binding
                     protein)"
                     /codon_start=1
                     /product="tetranectin precursor"
                     /protein_id="NP_001385567.1"
                     /db_xref="GeneID:100912012"
                     /db_xref="RGD:1311031"
                     /translation="MGFWGTYLLFCLFSFLSQATTESPTPKTKKAATAKKDLVSPKMF
                     EELKNRLDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQG
                     GTLGTPQSELENEALFEYARQSVGSEAELWLGLNDMASEGAWVDMTGGRLAYKNWETE
                     ITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV"
     exon            207..305
                     /gene="Clec3b"
                     /gene_synonym="Tna"
                     /inference="alignment:Splign:2.1.0"
     exon            306..980
                     /gene="Clec3b"
                     /gene_synonym="Tna"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagacagagg tccttgtgtg cacagcctta agacgtgcag cccaggctgc agtggccact
       61 gctttctgac ccagtcactg cagccagcag cagcagtatg ggattttggg gtacctacct
      121 gctcttctgc ctcttctcct tcctgtccca ggccactaca gagtcaccca cccccaagac
      181 caagaaggct gcaactgcca agaaagattt ggtgagccca aagatgtttg aggagctcaa
      241 gaacaggttg gatgtcctgg cccaggaggt ggccctgctg aaggagaagc aggccttaca
      301 gactgtgtgc ctgaagggca ccaaggtgaa cttgaagtgc ctcctggcct tcacccaacc
      361 gaagaccttc catgaggcga gcgaggactg catctcacaa gggggcacgc tgggcacgcc
      421 gcagtctgag ctagagaatg aggcgctgtt cgagtatgcg cgccagagcg tgggcagcga
      481 ggcggagctc tggctgggtc tcaacgacat ggcttcggaa ggcgcctggg tggacatgac
      541 cggcggccgc ctggcctaca agaactggga gacggagatt acgacgcaac ccgacggcgg
      601 caaagccgag aactgcgccg ccctctccgg cgcagccaac ggcaagtggt tcgacaagcg
      661 atgtcgcgat cagttgccct acatctgcca gtttgccatt gtgtagccca gccttttcta
      721 tctcggccct ccggggctgg gcctgggcca gggaggggtg tgaaccgcaa agagcagacc
      781 gctgctcatg ggtggggctt tgtaggcttg ctgtgtgggc ggggtgtcgg tgggctgagc
      841 tgagtggggc gggcctggtg cttctcaggg agagacaagt tgttgcagag cccagagggg
      901 cgcggagact tttctgtccc tctctctgct tgtttttttt tttttttttt tgcaaataaa
      961 gttggtgcag aattcctgaa
//
