LOCUS       NM_001012459            1955 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus C-type lectin domain containing 11A (Clec11a),
            mRNA.
ACCESSION   NM_001012459 XM_344888
VERSION     NM_001012459.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1955)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   2  (bases 1 to 1955)
  AUTHORS   Hollenbeck,S.T., Sakakibara,K., Faries,P.L., Workhu,B., Liu,B. and
            Kent,K.C.
  TITLE     Stem cell factor and c-kit are expressed by and may affect vascular
            SMCs through an autocrine pathway
  JOURNAL   J Surg Res 120 (2), 288-294 (2004)
   PUBMED   15234225
  REMARK    GeneRIF: Dramatic increase in c-kit expression observed in the rat
            carotid artery after balloon injury suggests SCF/c-kit signaling
            may affect smooth muscle cell function via an autocrine pathway.
REFERENCE   3  (bases 1 to 1955)
  AUTHORS   Otsuka,F. and Shimasaki,S.
  TITLE     A negative feedback system between oocyte bone morphogenetic
            protein 15 and granulosa cell kit ligand: its role in regulating
            granulosa cell mitosis
  JOURNAL   Proc Natl Acad Sci U S A 99 (12), 8060-8065 (2002)
   PUBMED   12048244
  REMARK    GeneRIF: negative feedback with kit ligand (Scgf) and oocyte BMP15
            regulated granulosa cell mitosis
REFERENCE   4  (bases 1 to 1955)
  AUTHORS   Hiraoka,A., Yano Ki,K., Kagami,N., Takeshige,K., Mio,H., Anazawa,H.
            and Sugimoto,S.
  TITLE     Stem cell growth factor: in situ hybridization analysis on the gene
            expression, molecular characterization and in vitro proliferative
            activity of a recombinant preparation on primitive hematopoietic
            progenitor cells
  JOURNAL   Hematol J 2 (5), 307-315 (2001)
   PUBMED   11920266
REFERENCE   5  (bases 1 to 1955)
  AUTHORS   Mio,H., Kagami,N., Yokokawa,S., Kawai,H., Nakagawa,S., Takeuchi,K.,
            Sekine,S. and Hiraoka,A.
  TITLE     Isolation and characterization of a cDNA for human mouse, and rat
            full-length stem cell growth factor, a new member of C-type lectin
            superfamily
  JOURNAL   Biochem Biophys Res Commun 249 (1), 124-130 (1998)
   PUBMED   9705843
REFERENCE   6  (bases 1 to 1955)
  AUTHORS   Bannwarth,S., Giordanengo,V., Lesimple,J. and Lefebvre,J.C.
  TITLE     Molecular cloning of a new secreted sulfated mucin-like protein
            with a C-type lectin domain that is expressed in lymphoblastic
            cells
  JOURNAL   J Biol Chem 273 (4), 1911-1916 (1998)
   PUBMED   9442024
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090344.1.
            
            On Apr 20, 2005 this sequence version replaced XM_344888.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090344.1, CO557138.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1955
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1955
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /note="C-type lectin domain containing 11A"
                     /db_xref="GeneID:29313"
                     /db_xref="RGD:3627"
     exon            1..265
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1105
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /note="stem cell growth factor; lymphocyte secreted C-type
                     lectin; C-type lectin domain family 11, member A;
                     osteolectin"
                     /codon_start=1
                     /product="C-type lectin domain family 11 member A
                     precursor"
                     /protein_id="NP_001012477.1"
                     /db_xref="GeneID:29313"
                     /db_xref="RGD:3627"
                     /translation="MQAAWLLGALLVPHLLSFGHGARGHGKEWEGVWGGALEEERDRE
                     SLMLKNLQEALGLPTGVGNKDNLAENSEGKEVWEATETQGEEEEEETTTTPSSSPTPF
                     PSPSPTSEDTVTYILGRLASLDAGLHQLHIRLHVLDTRVVELTQGLRRLRDAASDTRD
                     SVQALKEVQVRSEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQ
                     PADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRALSPE
                     SGAQPSAASHPLSPDQPNGGILENCVAQASDDGSWWDHDCERRLYFVCEFPF"
     exon            266..467
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /inference="alignment:Splign:2.1.0"
     exon            468..659
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /inference="alignment:Splign:2.1.0"
     exon            660..1927
                     /gene="Clec11a"
                     /gene_synonym="Scgf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaggttcaa ggggctagtg atctgcccac cagactggga cacttgctag ttctataccc
       61 caaccctacc ccaggctttc tgatctctac tagtctgggc gctgggaagt ccagctggat
      121 gcaggcagcc tggctcttgg gggccctact ggtccctcac cttttgagtt ttggccatgg
      181 agcccgaggt catgggaagg aatgggaagg agtctgggga ggtgccctgg aggaggagcg
      241 agatcgggag tcactgatgt tgaagaatct ccaggaggcc ctagggctgc ccactggggt
      301 gggaaataag gataatcttg ctgaaaactc tgaaggcaaa gaggtctggg aggccacgga
      361 gactcaaggg gaagaagagg aagaggaaac caccacaaca ccttcttcta gccccactcc
      421 tttccccagc ccttctccta catcagagga cacagtcact tacatcctgg gccgcttggc
      481 cagcctcgat gcaggcctac accaattgca catccgtctg catgttttgg acacccgtgt
      541 ggttgagctg acccaggggc tgcggcggct gcgggatgcc gcgagtgaca cccgcgactc
      601 agtgcaagct ctgaaggagg tacaggtccg ttctgagcag gagcacggcc gcttggaggg
      661 ctgcctgaag ggcctgcgcc taggccacaa atgcttcctg ctctcgcgag acttcgagac
      721 acaggcggcg gcgcaagcgc ggtgtaaggc gcgaggtggg agtttagcgc agcctgcgga
      781 ccgccagcaa atggatgctc taagccggta cttacgagct gctcttgccc cctacaactg
      841 gccagtgtgg ctgggagtgc acgaccggcg ctcggagggg ctctaccttt tcgagaacgg
      901 ccagcgcgtg tcattcttcg cctggcaccg cgcactcagc ccggagtccg gcgcccagcc
      961 tagtgcggca tcccatccac ttagcccgga tcagcccaat ggcggcatcc tggagaactg
     1021 cgtggcccag gcctcagacg acggctcctg gtgggaccat gactgtgagc ggcgcctcta
     1081 cttcgtctgc gagttccctt tctagagagc aggtctctgc cgcggagctc tagcgcacat
     1141 tctgcaccgt acaccgcgca ccctactgtt aggggtctgg ggtcgctcag agattaagca
     1201 agaccatgga tacattttaa taagaagagg cttttaattt tagatactgg cacccagact
     1261 gattggggcc aaggtctaca cctgagatcg cttccaagat gcaagcccta gctattatca
     1321 gcccagagct tataaaggca aatcccacaa gattgcatgt agcctgatga catggaggca
     1381 ggggcttaaa ttttaacata tatgtcttgt agttgtccta gtcatccttt gagcagagga
     1441 agcaagattg attacaaaag cagagatagc agttagtcgt acaactaaat ttgctagaac
     1501 agcaaatttt acaagaccaa tcaatttcaa aatagtcttc aatatctggg agaaagggga
     1561 agtggactgc tagtgtacag cctgcacaag ctaggagctt tcgtcttaga gccatatttg
     1621 ctttggtctc tcaagcgtag tgagtctaaa cttctaaatg taatgttgaa tacctacggt
     1681 gtacattctg caccctgtac cctacactgc gccctacatc ccactctgta cacctttcat
     1741 tctacaacct acatagtgca acctgcacct tgaaccctcc ttgggccaga agtgccacca
     1801 atcctggctg gtcccctacc cccaccctga gagatagcct gtacaacttc tccatgtccc
     1861 cccacctgtc tttgaaactt caaggtccca actaggcccg gtgccaataa atccttttaa
     1921 aatataaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
