LOCUS       NM_001102364            1544 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus claudin 6 (Cldn6), mRNA.
ACCESSION   NM_001102364 XM_001055688 XM_220202
VERSION     NM_001102364.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1544)
  AUTHORS   Harris,H.J., Davis,C., Mullins,J.G., Hu,K., Goodall,M.,
            Farquhar,M.J., Mee,C.J., McCaffrey,K., Young,S., Drummer,H.,
            Balfe,P. and McKeating,J.A.
  TITLE     Claudin association with CD81 defines hepatitis C virus entry
  JOURNAL   J Biol Chem 285 (27), 21092-21102 (2010)
   PUBMED   20375010
REFERENCE   2  (bases 1 to 1544)
  AUTHORS   Krause,G., Winkler,L., Mueller,S.L., Haseloff,R.F., Piontek,J. and
            Blasig,I.E.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   3  (bases 1 to 1544)
  AUTHORS   Nunes,F.D., Lopez,L.N., Lin,H.W., Davies,C., Azevedo,R.B., Gow,A.
            and Kachar,B.
  TITLE     Distinct subdomain organization and molecular composition of a
            tight junction with adherens junction features
  JOURNAL   J Cell Sci 119 (Pt 23), 4819-4827 (2006)
   PUBMED   17130295
REFERENCE   4  (bases 1 to 1544)
  AUTHORS   Morita,K., Furuse,M., Yoshida,Y., Itoh,M., Sasaki,H., Tsukita,S.
            and Miyachi,Y.
  TITLE     Molecular architecture of tight junctions of periderm differs from
            that of the maculae occludentes of epidermis
  JOURNAL   J Invest Dermatol 118 (6), 1073-1079 (2002)
   PUBMED   12060405
REFERENCE   5  (bases 1 to 1544)
  AUTHORS   Morita,K., Furuse,M., Fujimoto,K. and Tsukita,S.
  TITLE     Claudin multigene family encoding four-transmembrane domain protein
            components of tight junction strands
  JOURNAL   Proc Natl Acad Sci U S A 96 (2), 511-516 (1999)
   PUBMED   9892664
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Aug 24, 2007 this sequence version replaced
            XM_220202.3, XM_001055688.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168250.1, BU671697.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1544
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1544
                     /gene="Cldn6"
                     /note="claudin 6"
                     /db_xref="GeneID:287098"
                     /db_xref="RGD:1308837"
     exon            1..115
                     /gene="Cldn6"
                     /inference="alignment:Splign:2.1.0"
     exon            116..1544
                     /gene="Cldn6"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..791
                     /gene="Cldn6"
                     /codon_start=1
                     /product="claudin-6"
                     /protein_id="NP_001095834.1"
                     /db_xref="GeneID:287098"
                     /db_xref="RGD:1308837"
                     /translation="MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQ
                     MVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGA
                     KCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKREL
                     GASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNY
                     V"
ORIGIN      
        1 cccagctctg cgggcgccgc cattaagccc ctcctggtct cgcactccta ggcttggata
       61 tcgtgggtgg ccgaaccgga caggacgccc tcggacaaag ctgactgagc atttgccccc
      121 tcaacctcat catggcctct actggtctgc aaatcttggg gattgtcctg accctgcttg
      181 gctgggtcaa cgccctggtg tcctgtgccc tgccgatgtg gaaggtgacc gccttcatcg
      241 gcaacagcat cgttgtggcc cagatggtgt gggaggggct atggatgtcc tgtgtggtcc
      301 agagcactgg tcagatgcag tgcaaggtgt acgactcgct gctggcgctg ccccaggacc
      361 tgcaggctgc cagagccctc tgtgtcatca ccctcctcat tgtcctgctt ggcctactcc
      421 tgtaccttgc cggagccaag tgcactacct gtgtggaaga caagaattcc aagtctcgtc
      481 tggtgctcat ctctggtgtc atcttcgtca tctccggggt cctgaccctc attcccatct
      541 gctggactgc ccacgccatc atccaggact tctacaaccc cttggtcgca gacgctcaaa
      601 agcgagagct aggggcctcc ctctacctgg gttgggccgc ctcaggcctt ttgctgatag
      661 gtggagggct gctatgctgc gcctgctctt ctggagggac ccagggaccc agccattatg
      721 tggcccgcta ttcttcgcct gtcccacatt ctcggggacc ctccgaatac ccctccaaga
      781 attatgtctg atgcccactg gggagtgagg ctctactggc cagagaacct gagctgagcc
      841 gtgagaaatg atgtggggta gtttttgggg tttgtcttgt tccttgtttt ccttttgcaa
      901 tgctgggtat gaaacctggg gccccgcata tttggtaggc aagcactcca cagtgagctg
      961 tgtggtaccc tgccccctag ggttggttcc acctgttttt gagacaggct ctccctaatg
     1021 gcgctctgac tgacctccag ctctcgtttt tttttttttt ttgtttgttt gttttttttt
     1081 cctgtctcac cctgagtccg aactccgcct atcgctccgt tactggcatt tctcgctttt
     1141 acctactgta gctggaggga tttgaccctg agttcctgtg tctttattca ttctggggat
     1201 ctactgtgca aagtgtttta aggctgcctg tgaatctggc ctttgcgatt ctcaaaatgg
     1261 cttgtcccga gagttcctgc tgtggctgga ggtaactcac aggacagaca cacccgctcc
     1321 tggtcaaact cttcccagtc ctggaagggc aggtgataat ttacctaaga attttcaact
     1381 cagtcttcca acctttggcc cctgaatccc atcaccaagg ttactgtgta ctctccccac
     1441 atacggtccc agctgtgctg tagaccctcc tcccccttac ctctaacctt gcacatttcc
     1501 ctgcccacac aatgttttac ttaataaaac atgatttttt tttt
//
