LOCUS       NM_001107135            2026 bp    mRNA    linear   ROD 18-FEB-2024
DEFINITION  Rattus norvegicus claudin 15 (Cldn15), mRNA.
ACCESSION   NM_001107135 XM_001076934 XM_222085
VERSION     NM_001107135.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2026)
  AUTHORS   Cai,M., Shao,J., Wang,Y., Yung,B., Li,J.N., Zhang,H.H., Li,Y.T. and
            Yao,D.B.
  TITLE     Claudin 14/15 play important roles in early wallerian degeneration
            after rat sciatic nerve injury
  JOURNAL   Chin J Traumatol 24 (6), 374-382 (2021)
   PUBMED   33903003
  REMARK    GeneRIF: Claudin 14/15 play important roles in early wallerian
            degeneration after rat sciatic nerve injury.
REFERENCE   2  (bases 1 to 2026)
  AUTHORS   Krause,G., Winkler,L., Mueller,S.L., Haseloff,R.F., Piontek,J. and
            Blasig,I.E.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   3  (bases 1 to 2026)
  AUTHORS   Fujita,H., Chiba,H., Yokozaki,H., Sakai,N., Sugimoto,K., Wada,T.,
            Kojima,T., Yamashita,T. and Sawada,N.
  TITLE     Differential expression and subcellular localization of claudin-7,
            -8, -12, -13, and -15 along the mouse intestine
  JOURNAL   J Histochem Cytochem 54 (8), 933-944 (2006)
   PUBMED   16651389
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000227.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001107135.4.
            
            On Oct 29, 2022 this sequence version replaced NM_001107135.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00155333,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-428               JACYVU010000227.1  976259-976686       c
            429-593             JACYVU010000227.1  972072-972236       c
            594-675             JACYVU010000227.1  969432-969513       c
            676-792             JACYVU010000227.1  969228-969344       c
            793-2026            JACYVU010000227.1  967907-969140       c
FEATURES             Location/Qualifiers
     source          1..2026
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..2026
                     /gene="Cldn15"
                     /note="claudin 15"
                     /db_xref="GeneID:304388"
                     /db_xref="RGD:1310678"
     exon            1..428
                     /gene="Cldn15"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..895
                     /gene="Cldn15"
                     /codon_start=1
                     /product="claudin-15"
                     /protein_id="NP_001100605.1"
                     /db_xref="GeneID:304388"
                     /db_xref="RGD:1310678"
                     /translation="MSIAVETFGFFMSALGLLMLGVTLPNSYWRVSTVHGNVITTNTI
                     FENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRC
                     TNVGNIDLSRKAKLLAIAGAFHILAGACGMVAISWYAVNITTDFFNPLYVGTKYELGS
                     ALYLGWSASLLSILGGICVFSTCCCDSKEDPATRVGLPYKPSTVVTARATSDESDVSF
                     GKYGKNAYV"
     exon            429..593
                     /gene="Cldn15"
                     /inference="alignment:Splign:2.1.0"
     exon            594..675
                     /gene="Cldn15"
                     /inference="alignment:Splign:2.1.0"
     exon            676..792
                     /gene="Cldn15"
                     /inference="alignment:Splign:2.1.0"
     exon            793..2026
                     /gene="Cldn15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcctctga cctgccagga agcagagcct cccagagacc gggcagaagc aatcagacct
       61 gacctccaga agacagcaga caagaaccgc agctggatga gcttcccttc aaccttctcc
      121 ctcctcagtc ttccttagca tctcacctgg aggagccacc tctatcccaa tccctggggc
      181 tcaagccccc ttgcgggacc tgcatcccag catgtcgata gctgtggaga cctttggttt
      241 cttcatgtca gccctgggac tgctgatgct gggggtgacc cttccaaaca gctactggag
      301 agtgtctacc gtccatggga acgtcatcac cactaacacc atcttcgaga acctgtggta
      361 cagctgtgcc accgactccc tgggagtctc caactgctgg gacttcccgt ccatgctggc
      421 cctctctggc tatgtccagg gctgccgagc tctcatgatc accgccatcc tcctgggctt
      481 cctgggcctc tttctaggca tggtggggct ccgctgcacc aacgtgggca acatcgacct
      541 ctccagaaag gccaagctgc tggccattgc aggggccttc cacatacttg ctggagcctg
      601 tggcatggtt gctatctcat ggtatgctgt caacatcacc accgacttct tcaaccccct
      661 gtatgttgga accaagtatg aactgggctc tgccctctac ttgggctgga gcgcctctct
      721 gctctccatc ctgggcggca tctgtgtctt ctccacctgc tgctgtgact ccaaggagga
      781 cccagccacc agggtgggac ttccctacaa gccttctacg gttgtgacag cccgagccac
      841 ttccgatgaa agtgacgtca gctttggtaa atatggcaaa aatgcctacg tgtaggagct
      901 ccggcctggt ggacagcgtt tcttgtccca ctgtccccag cagaaaacgt ccccaggacc
      961 tgtgggagga ctagtctcca gttaataacc tgaggacagg ccaaatttcc aggcctcagc
     1021 ctatgccggg aagccactac ccactctggg cacaccttat ctggcactcc agtctctccc
     1081 aggaacagaa gcttcagggg caacttgcat ggcctcccac agctggactc aaggggacag
     1141 aggtgtctgc agcatgtgac tctatagaaa tatgtgcata aatcaatgta tattgtgatt
     1201 gtacaggggg ctcctggggt cctgaagtta cgaccacgga agggggtcat tttcaagcca
     1261 tagactgtca agtctgccca ctttgggggc tgtgtcatct agtgagacgg tgggccaggg
     1321 agctggggac gtggctcagt gagtttagag tgtttgctac acaagtatga ggacctgagt
     1381 tcaaatcccc agtacccgtg tgaaaagcgg gccctggaca cactcctgca gcccaagtgt
     1441 tgctagggag gggctctgag gctcactggc ttccaacctc actccaggtt ctatgtgagt
     1501 tcaatctcaa gggaatgagg tggagcacga tagagcaggg tgctgggagc cctcttccga
     1561 cctttgcggg cacacagact tgtgcgtaga ggacacacgc gtgcgcgcac acacacacac
     1621 acacacattc tcaataaaag gatttgaaag ggggaaatcg ctaacaactg ctccgaatca
     1681 cccacctcag gagactgtta atagctggga agcttctggc ccactgaaag ttcctctctg
     1741 ttgacccctg acctattttc tcacagcctc acaaaggggc agttgattta gaacgggcgg
     1801 gcattggtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     1861 gtgtgtgtgt ttaaagtcga tttggggttt aaaataaagg tttttttttt tttggttctt
     1921 tttttcggag ctggggaccg aacccagggc cttgcgcttc ccaggcaagc gctctaccac
     1981 tgagctaaat ccccaacccc aaaataaagg tatttttaaa gatgca
//
