LOCUS       NM_001013429            1549 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus claudin 14 (Cldn14), mRNA.
ACCESSION   NM_001013429 XM_221634
VERSION     NM_001013429.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Cai M, Shao J, Wang Y, Yung B, Li JN, Zhang HH, Li YT and Yao DB.
  TITLE     Claudin 14/15 play important roles in early wallerian degeneration
            after rat sciatic nerve injury
  JOURNAL   Chin J Traumatol 24 (6), 374-382 (2021)
   PUBMED   33903003
  REMARK    GeneRIF: Claudin 14/15 play important roles in early wallerian
            degeneration after rat sciatic nerve injury.
REFERENCE   2  (bases 1 to 1549)
  AUTHORS   Frische S, Alexander RT, Ferreira P, Tan RSG, Wang W, Svenningsen
            P, Skjodt K and Dimke H.
  TITLE     Localization and regulation of claudin-14 in experimental models of
            hypercalcemia
  JOURNAL   Am J Physiol Renal Physiol 320 (1), F74-F86 (2021)
   PUBMED   33283646
  REMARK    GeneRIF: Localization and regulation of claudin-14 in experimental
            models of hypercalcemia.
REFERENCE   3  (bases 1 to 1549)
  AUTHORS   Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig
            IE.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   4  (bases 1 to 1549)
  AUTHORS   Charoenphandhu N, Wongdee K, Tudpor K, Pandaranandaka J and
            Krishnamra N.
  TITLE     Chronic metabolic acidosis upregulated claudin mRNA expression in
            the duodenal enterocytes of female rats
  JOURNAL   Life Sci 80 (19), 1729-1737 (2007)
   PUBMED   17383680
REFERENCE   5  (bases 1 to 1549)
  AUTHORS   Nunes FD, Lopez LN, Lin HW, Davies C, Azevedo RB, Gow A and Kachar
            B.
  TITLE     Distinct subdomain organization and molecular composition of a
            tight junction with adherens junction features
  JOURNAL   J Cell Sci 119 (Pt 23), 4819-4827 (2006)
   PUBMED   17130295
REFERENCE   6  (bases 1 to 1549)
  AUTHORS   Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem
            P, Lehrach H, Yaspo ML and Janitz M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1549)
  AUTHORS   Wilcox ER, Burton QL, Naz S, Riazuddin S, Smith TN, Ploplis B,
            Belyantseva I, Ben-Yosef T, Liburd NA, Morell RJ, Kachar B, Wu DK,
            Griffith AJ, Riazuddin S and Friedman TB.
  TITLE     Mutations in the gene encoding tight junction claudin-14 cause
            autosomal recessive deafness DFNB29
  JOURNAL   Cell 104 (1), 165-172 (2001)
   PUBMED   11163249
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091387.1.
            
            On Apr 20, 2005 this sequence version replaced XM_221634.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091387.1, CO562732.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1549
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1549
                     /gene="Cldn14"
                     /note="claudin 14"
                     /db_xref="GeneID:304073"
                     /db_xref="RGD:1309165"
     exon            1..400
                     /gene="Cldn14"
                     /inference="alignment:Splign:2.1.0"
     exon            401..1416
                     /gene="Cldn14"
                     /inference="alignment:Splign:2.1.0"
     CDS             481..1200
                     /gene="Cldn14"
                     /codon_start=1
                     /product="claudin-14"
                     /protein_id="NP_001013447.1"
                     /db_xref="GeneID:304073"
                     /db_xref="RGD:1309165"
                     /translation="MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAV
                     SYLKGLWMECVWHSTGIYQCQIYRSLLALPRDLQAARALMVISCLLSGMACACAVVGM
                     KCTRCAKGTPAKTTFAVLGGALFLLAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEI
                     GQALYLGFISSSLSLIGGTLLCLSCQDEGPYRPYQPQSRAGATTTATAPAYRPPAAYK
                     DNRAPSVTSAAHSGYRLNDYV"
ORIGIN      
        1 cagggaggtc agaaaaggct gacacaggac agtgagtagg aaaggtgagg tttcacctgc
       61 caggcacagg gacccattag ccagccgtgt gtagacatct ctggcattct tgtatcaaat
      121 gcagatatga catttctggt tggtcttgaa tgtttgcctc agcagggcca ccttgtaggg
      181 cgcaccagct agttaatctt ctaaccagag ggcatgtatg cccacgcagg ccccactcag
      241 agaccgtaat tgaccagacc actgtctcgc aagcaccctg gccttgaagc tcccatttgg
      301 tgaatgaggc taagctggaa gtcttcagtg tccttgctgt gtctccgggg tctacctgcg
      361 tcggagtgtc gaggtggatg ggactcgagc tgttctgtat gcctcccgcg ggcacctaag
      421 gaccagatcc atccctgagg acctgggcac tgcccggcgc ggctagcgga gccctcgacc
      481 atggccagca cagcggtcca gctcctaggc ttcctgctta gcttcctggg catggtggga
      541 acgctcatca ctactatcct gccgcactgg cggaggacgg cccatgtggg caccaacatc
      601 ctgacggccg tgtcctacct gaagggactg tggatggagt gtgtgtggca cagcacaggc
      661 atctaccagt gtcagatcta ccgctcgctg ctggcgctac cccgggacct acaggcggcc
      721 cgggcgctca tggtcatctc ctgcctgctg tcgggcatgg cctgcgcctg cgccgtagtg
      781 ggcatgaagt gcactcgctg tgccaagggc acacccgcca agaccacctt cgcggtgttg
      841 ggaggcgcgc tcttcctgct ggcaggcctg ctgtgcatgg tggctgtgtc ctggaccacg
      901 aatgatgtgg tgcagaattt ttacaaccct ctgctgccca gtggcatgaa gtttgagatc
      961 ggccaggccc tgtacctggg cttcatctcc tcatccctgt ctctcatcgg gggcaccctg
     1021 ctctgcctgt cgtgccagga cgagggcccc tacagaccct accagcccca gtccagggct
     1081 ggggccacca ccacagccac cgcccctgcc taccgcccac cagcagccta caaggacaac
     1141 cgtgccccct cggtgacctc agctgcacac agtgggtaca ggttgaatga ctatgtgtga
     1201 gttccctccc caggcttctg ccagggatgt tgggccccaa aggaccagtg aaggatgtag
     1261 agtcctttgt aaacgtgggg aagtaagtct ggaatacagg gaagaagggt gctcttcaaa
     1321 gcaaagactt ctaaaaagtg ctggttttgt atttattata tgtatttatg tgggtggttt
     1381 aataagagct caataaagaa tacttggaag attggcaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
