LOCUS       NM_001106058            1331 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus claudin 10 (Cldn10), mRNA.
ACCESSION   NM_001106058 XM_001074876 XM_214250
VERSION     NM_001106058.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Hadj-Rabia,S., Brideau,G., Al-Sarraj,Y., Maroun,R.C.,
            Figueres,M.L., Leclerc-Mercier,S., Olinger,E., Baron,S.,
            Chaussain,C., Nochy,D., Taha,R.Z., Knebelmann,B., Joshi,V.,
            Curmi,P.A., Kambouris,M., Vargas-Poussou,R., Bodemer,C.,
            Devuyst,O., Houillier,P. and El-Shanti,H.
  TITLE     Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX
            syndrome
  JOURNAL   Genet Med 20 (2), 190-201 (2018)
   PUBMED   28771254
REFERENCE   2  (bases 1 to 1331)
  AUTHORS   Klar,J., Piontek,J., Milatz,S., Tariq,M., Jameel,M.,
            Breiderhoff,T., Schuster,J., Fatima,A., Asif,M., Sher,M.,
            Mabert,K., Fromm,A., Baig,S.M., Gunzel,D. and Dahl,N.
  TITLE     Altered paracellular cation permeability due to a rare CLDN10B
            variant causes anhidrosis and kidney damage
  JOURNAL   PLoS Genet 13 (7), e1006897 (2017)
   PUBMED   28686597
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1331)
  AUTHORS   Zemke,A.C., Snyder,J.C., Brockway,B.L., Drake,J.A., Reynolds,S.D.,
            Kaminski,N. and Stripp,B.R.
  TITLE     Molecular staging of epithelial maturation using secretory
            cell-specific genes as markers
  JOURNAL   Am J Respir Cell Mol Biol 40 (3), 340-348 (2009)
   PUBMED   18757308
REFERENCE   4  (bases 1 to 1331)
  AUTHORS   Krause,G., Winkler,L., Mueller,S.L., Haseloff,R.F., Piontek,J. and
            Blasig,I.E.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   5  (bases 1 to 1331)
  AUTHORS   Ohta,H., Adachi,H. and Inaba,M.
  TITLE     Developmental changes in the expression of tight junction protein
            claudins in murine metanephroi and embryonic kidneys
  JOURNAL   J Vet Med Sci 68 (2), 149-155 (2006)
   PUBMED   16520537
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473951.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214250.4, XM_001074876.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q24"
     gene            1..1331
                     /gene="Cldn10"
                     /note="claudin 10"
                     /db_xref="GeneID:290485"
                     /db_xref="RGD:1308027"
     exon            1..406
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..1110
                     /gene="Cldn10"
                     /codon_start=1
                     /product="claudin-10"
                     /protein_id="NP_001099528.1"
                     /db_xref="GeneID:290485"
                     /db_xref="RGD:1308027"
                     /translation="MSRAQISALVCGVGGFGALVAATTSNEWKVTTRASSVITATWVY
                     QGLWMNCAAGSMASTALEIIAFVVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYFA
                     NLWKMCVTDSTGVANCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTK
                     VGGSDKAKAKIACLAGVVFILSGLCSMTGCSLYANKITTEFFDPLFMEQKYELGAALF
                     IGWAGASLCIIGGVIFCFSISDNNKTPRMGYTYNGPTSVMSSRTKYQGGEGDFKTTGP
                     SKQFDKNAYV"
     exon            407..634
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
     exon            635..796
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
     exon            797..878
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
     exon            879..986
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1331
                     /gene="Cldn10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaaattcct ctacaaagtt ttggtatctc agtagggaat tagaaagatt atttaggcta
       61 tcgctaagat gcccttactt cactatactt aatcctaaat tcccatactt ggagccatca
      121 aagtatgaag aattgtcacc caccctcatg ggcgggctgt aacatttgtg ggagtcctgt
      181 ccagtggctg catgcctagg ccaccaaagc attcagtgtg gactgtgaca gcaggcaagg
      241 ctgagcaaca tgtccagggc gcagatctca gctctggtgt gtggcgttgg agggtttggt
      301 gctcttgtcg ctgccaccac atccaatgaa tggaaagtga ccacccgagc atcgtccgtg
      361 ataaccgcca cctgggttta ccagggtctg tggatgaact gcgcagccgg cagcatggct
      421 agcacggcct tggaaatcat cgccttcgtc gtctccatct cgggctgggt gctggtgtct
      481 tccacactac ccaccgacta ctggaaggtc tccaccatcg atggcactgt catcaccacc
      541 gccacttatt ttgccaacct gtggaagatg tgcgttaccg attccaccgg tgtcgccaac
      601 tgcaaggact tcccctccat gctggcgctg gatggttaca tccaggcgtg tagaggacta
      661 atgattgccg cggtcagcct gggcttcttc ggttccattt ttgcactctt tggaatgaag
      721 tgtaccaaag tcggaggctc ggataaagcc aaagctaaga ttgcttgctt ggctggggtt
      781 gtattcatat tgtcaggtct gtgttccatg acgggctgtt ccctgtacgc gaacaaaatc
      841 acaacggaat tctttgatcc cctctttatg gagcaaaagt atgaattggg ggctgccctc
      901 ttcatcggat gggcaggagc ttctctctgc atcattggcg gtgtcatatt ttgcttttca
      961 atatccgaca acaacaaaac acccagaatg ggctacacgt acaatggacc cacgtcagtc
     1021 atgtcttccc ggaccaagta tcaaggcgga gaaggagatt ttaaaaccac aggcccttca
     1081 aaacagtttg ataaaaatgc ctatgtctaa agagctctgg caagccgcgt ctcgagtttg
     1141 ttgcgcaaga gaactgttct cacaatggtc cttccaaggc tcccctgtaa ttatcactta
     1201 agctgttttt ttttttttaa aatatgaatt tgaagaatgt tgattggatg taaatgttct
     1261 tatagttata tactaatcat ttttttctgt tgtgcctttc tataagggaa ataaacaggt
     1321 tatttacagg a
//
