LOCUS       XM_008764297            2231 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus chloride voltage-gated channel Kb
            (Clcnkb), transcript variant X3, mRNA.
ACCESSION   XM_008764297
VERSION     XM_008764297.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008764297.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008764297.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2231
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2231
                     /gene="Clcnkb"
                     /gene_synonym="ClC-K2L; Clck2; Clcnk1l"
                     /note="chloride voltage-gated channel Kb; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 8 ESTs, 3 long SRA reads, 3 Proteins, and 90%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:79430"
                     /db_xref="RGD:628639"
     CDS             69..2003
                     /gene="Clcnkb"
                     /gene_synonym="ClC-K2L; Clck2; Clcnk1l"
                     /codon_start=1
                     /product="chloride channel protein ClC-Kb isoform X2"
                     /protein_id="XP_008762519.1"
                     /db_xref="GeneID:79430"
                     /db_xref="RGD:628639"
                     /translation="MEEIVGLREGSPRKPVPLQELWRPCPRIRRNIQGSLEWLKERLF
                     RVGEDWYFLVALGVLMALISYAMNFAIGRVVRGSGIPEVKTILTGVILEDYLDIKNFG
                     AKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPENKTKEMELLAA
                     GAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNSEQE
                     TITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYCQRTSLFFLKANGFTSKL
                     LATSKPLYSALAAVVLASITYPPGVGRFMASRLSMSEYLETLFDNNSWALMTKNSSPP
                     WSAEPDPQNLWLEWCHPQMTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFVYGAA
                     IGRLFGEVLSLAFPEGIVAGGKVSPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVSG
                     QIVHALPVLMAVLAANAICQSYQPSFYDGTIIVKKLPYLPWIRGRKIGSHLVTVGHFM
                     NCTLTTLAKDMPLEEVIKVVISTDVTQYPLVETTESQVLVGIVKRTHLVQSLHTDSAS
                     WAPGQQPCLQDILANGCPTQPVTLQLSTETSLHETHNLFELLNLQLLFVTSRGRAVGS
                     VSWVELKKAISTLTNPPAPK"
ORIGIN      
        1 acaaacaaag aagctgtgtt ggaggagggc ctgttggggt ttcggcaggg cacgctgaca
       61 gagaaaccat ggaggaaata gtggggcttc gagagggctc ccccaggaag ccagtgcctc
      121 tgcaagaact ctggaggccg tgcccacgaa tccgcagaaa catccagggg agcctagagt
      181 ggctgaaaga gcggctgttc cgtgtgggtg aggactggta cttcctggtg gctctcgggg
      241 tgctcatggc tctgatcagc tatgccatga actttgctat tggacgtgtg gtcagagggt
      301 ctgggatccc cgaggtgaaa accatcttga cgggtgtgat cctggaggac tacctagaca
      361 ttaagaactt cggggccaag gtggtgggcc tctcctgcac cctggcaaca ggcagtacca
      421 tcttcctggg aaaactgggc ccctttgtgc acctgagcgt gatgatcgct gcttacctgg
      481 gccgcgtgcg caccaagacc gtcggggaac ctgagaacaa gaccaaagaa atggaattgt
      541 tggctgcagg agcagcagtg ggtgtggcca cggtcttcgc cgccccaatc agtggtgttc
      601 tgttcagcat cgaggtcatg tcctctcact tctccgtctg ggattactgg aggggcttct
      661 tcgctgccac ctgcggggcc ttcatgtttc acctcctggc ggtcttcaac agtgaacagg
      721 agaccatcac ctccatttac aagaccagct tcccagtgga catacccttt gacttaccag
      781 agatcttctt ttttgtggcc ttgggggcca tctgtggcat cctgagttgc gggtacaact
      841 actgccagcg gacttcctta tttttcctca aggccaatgg gttcacctcc aaactgctgg
      901 ctaccagcaa gcccttgtac tcagctctgg ctgctgtggt cctggcctcc atcacctatc
      961 cacctggtgt gggtcgcttc atggcttccc ggctgtctat gtcagagtac ttggagacac
     1021 tgtttgacaa caactcttgg gcactgatga ccaagaactc gtccccaccc tggtcagcgg
     1081 agcctgatcc ccagaacctg tggttggaat ggtgtcatcc acagatgact gtctttggga
     1141 cactagtctt cttcctggtc atgaagttct ggatgctgat tttggccacc accatcccca
     1201 tccccgcagg atactttttg cccatctttg tctacggagc tgccatcggg cgcctctttg
     1261 gggaggttct atctttggcc ttcccagagg gcattgtggc tggaggcaag gtcagtccca
     1321 tcatgcccgg ggcctatgct ctggcaggtg ctgctgcctt ctcaggggcg gtgacccaca
     1381 ccctctccac agcattgctg gcctttgagg tatccggcca gatcgttcat gcactgcctg
     1441 tgctgatggc cgtgctggcg gccaatgcca tctgtcagag ctaccagccc tctttctacg
     1501 acggcaccat cattgtcaag aaactgccgt acctgccgtg gatccgtggt cgtaagattg
     1561 gttcccacct tgtgactgtg ggtcacttca tgaactgtac cctcaccacg ctggccaagg
     1621 acatgcccct ggaggaagtg atcaaagttg tgatctccac ggatgtgact cagtaccccc
     1681 tggtggagac gacagagtct caggtcctgg tgggcattgt caaaaggacc cacttggtgc
     1741 agtccctcca taccgattca gcttcctggg ctccaggcca gcagccctgt ctccaggata
     1801 tcttggctaa cggctgcccc acccagccag tgacacttca gctgtccacg gagacctccc
     1861 tgcatgagac gcacaacctc tttgagctgc tgaaccttca gctgctgttc gtgacgtcac
     1921 gaggcagagc tgtgggctct gtgtcctggg tggagctgaa gaaagcaatt tcaaccctga
     1981 ccaatccgcc cgctcccaag tgagtcagcc tgggagtcgg cagcctggcg cccagtcgct
     2041 ctcagctgct gcagggcatc tccactttgc agaggagagg actccacatt cacctctccc
     2101 caccctgaag gagctggttg taaatgaaga caccaatgcg ttctgtcaca tcgggaccct
     2161 tggtccttct agggttgtct gctgctaacc aagacttctg agaaaaataa aactgatttc
     2221 tggagccact g
//
