LOCUS       NM_133414               3554 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Rattus norvegicus chloride channel CLIC-like 1 (Clcc1), mRNA.
ACCESSION   NM_133414
VERSION     NM_133414.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3554)
  AUTHORS   Chu,Q., Martinez,T.F., Novak,S.W., Donaldson,C.J., Tan,D.,
            Vaughan,J.M., Chang,T., Diedrich,J.K., Andrade,L., Kim,A.,
            Zhang,T., Manor,U. and Saghatelian,A.
  TITLE     Regulation of the ER stress response by a mitochondrial
            microprotein
  JOURNAL   Nat Commun 10 (1), 4883 (2019)
   PUBMED   31653868
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3554)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 3554)
  AUTHORS   Nagasawa,M., Kanzaki,M., Iino,Y., Morishita,Y. and Kojima,I.
  TITLE     Identification of a novel chloride channel expressed in the
            endoplasmic reticulum, golgi apparatus, and nucleus
  JOURNAL   J Biol Chem 276 (23), 20413-20418 (2001)
   PUBMED   11279057
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_133414.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB052922.1, AF117330.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                JAXUCZ010000002.1  198984511-198984542
            33-172              JAXUCZ010000002.1  198994398-198994537
            173-274             JAXUCZ010000002.1  199001329-199001430
            275-382             JAXUCZ010000002.1  199003050-199003157
            383-604             JAXUCZ010000002.1  199004771-199004992
            605-745             JAXUCZ010000002.1  199005414-199005554
            746-839             JAXUCZ010000002.1  199007179-199007272
            840-937             JAXUCZ010000002.1  199009124-199009221
            938-1084            JAXUCZ010000002.1  199009579-199009725
            1085-1426           JAXUCZ010000002.1  199011131-199011472
            1427-3554           JAXUCZ010000002.1  199012888-199015015
FEATURES             Location/Qualifiers
     source          1..3554
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..3554
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /note="chloride channel CLIC-like 1"
                     /db_xref="GeneID:170927"
                     /db_xref="RGD:708359"
     exon            1..32
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            33..172
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..1669
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /note="chloride channel CLIC-like protein 1; mid-1-related
                     chloride channel protein 1; Mid-1-related chloride channel
                     1; ER anion channel 1"
                     /codon_start=1
                     /product="chloride channel CLIC-like protein 1 precursor"
                     /protein_id="NP_596905.2"
                     /db_xref="GeneID:170927"
                     /db_xref="RGD:708359"
                     /translation="MLCSLLLCGCLLLITGYAHDDDWIDPTDMLNYDAASGTMRKSQA
                     KYGTSEKKEVNPDLSDAQELSDCLQRLDSLTHKVDDCEKKKMKDYESQSNPVFRRYLN
                     KILIEAGKLGLPDEDRVDVRYDAEILLTRQTLLEIQKFLSGEEWKPGALDDALSDILT
                     NFKSHDSEAWKWQFEDYFGVDPYNVFMVLLCLLCIVALVATELWTYVRWHTQLKRVCI
                     ISFLVSLGWNWIYLYKVAFAQHQANVAKMAPLNDVCAKKMDWTENLWEWFRISWTYKD
                     DPCQKYYELLIVNPIWLVPPTKALAVTFTNFVTEPLKYIGKGTGEFIKALMKEIPVLL
                     QIPVLVILALAVLGFCYGAGQSVPMLRHFRGPEREPPRALEPDDRRRQKELDYRFHGG
                     AGDADFSYRGPAGSIEQGPYDKMHACERDVLRQRQVNMRFPSGNKSPEVLRAFDLPDT
                     EAQEHPEVVPSHKPSIVNTSLKETSELPRESTLAECSQCAKDGSGQVPSTAESSPIVE
                     KAQLKTDSECRPHSTEAAAAAARGTDPVSSPCG"
     exon            173..274
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            275..382
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            383..604
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            605..745
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            746..839
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            840..937
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1084
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1426
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..3554
                     /gene="Clcc1"
                     /gene_synonym="ERAC1; Mclc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggacttct gcgcgagcgc acgttgtctg agccttgctc aggatgctgt gttcactgct
       61 cctttgtgga tgtctgttac tgatcactgg ttatgctcat gacgatgact ggattgaccc
      121 aacagatatg cttaattatg acgctgcttc gggaaccatg agaaaatcgc aggcaaaata
      181 tggtacctca gagaagaagg aagtgaaccc tgacttgtca gatgcccagg agttgtcaga
      241 ctgtttgcag agactggatt ctttaacgca caaggttgat gattgtgaaa agaagaaaat
      301 gaaagactat gaaagtcaaa gtaatcctgt ttttaggaga tatctaaata agattttaat
      361 tgaagcgggc aagcttggac ttcctgatga agacagagtg gatgtgcgtt atgatgctga
      421 gatcctcctt acaagacaga cactgttgga gatacagaag ttcctcagtg gagaggaatg
      481 gaagccagga gccttggatg atgcactaag tgatatttta accaatttta agtctcatga
      541 ctcagaagca tggaagtggc aatttgaaga ctattttgga gtagatccat acaatgtgtt
      601 tatggtactc ttgtgtctgc tctgcattgt ggcgttggtg gctacggagc tatggacata
      661 tgttcgctgg catacgcagt tgaaacgcgt ttgtatcatc agttttctcg tcagtttagg
      721 atggaattgg atttatctat ataaggtagc ttttgctcag catcaggcta atgttgccaa
      781 gatggcgccg ttaaacgatg tgtgtgctaa gaagatggat tggactgaaa acctctggga
      841 atggtttaga atttcatgga cctataagga tgacccatgc caaaagtact atgagctctt
      901 aatcgtcaac cctatttggt tggttccgcc aacaaaggct ctggcagtta cattcactaa
      961 ctttgtaacg gaaccattaa agtacattgg aaaaggaact ggtgaattca ttaaagcact
     1021 catgaaggag attccggtgt tacttcagat cccggtgctt gtgattctag ccttggctgt
     1081 cctgggcttc tgctatggtg ctggacagtc agttcctatg ctgagacact tccgtggtcc
     1141 tgaaagagaa cctccccgag cacttgagcc agatgacaga agacgacaga aggaacttga
     1201 ctatagattc catggtggag caggtgatgc agatttctct tacaggggcc cagctggctc
     1261 cattgaacaa ggcccttatg acaaaatgca tgcgtgtgag agagatgttt tgagacagag
     1321 acaagttaac atgagatttc cctctggcaa caagagccct gaagtgctcc gggcatttga
     1381 tttacctgac acagaggcac aagaacatcc agaagtggtt cccagccata aaccatccat
     1441 tgtgaataca agcctcaaag agactagtga actcccaaga gaaagcaccc tggcagaatg
     1501 cagccagtgt gccaaggatg gctctggcca agtccccagc actgctgaaa gctcacccat
     1561 cgtggagaag gcccagctga agacagactc tgagtgccgc ccacacagca cagaagctgc
     1621 agcagcagca gcacgtggga ctgatcctgt cagcagccca tgtggctaaa gaccaagggg
     1681 cagaccgacc acggctagag tcatctttga agtctgtatt gactcttctt tccttacaga
     1741 tacgttgaaa cttactacaa aactgctaac tttaaattaa tggttttaca gaccatcaga
     1801 gtatctctta gctgttagga catatcttgt attttagaac agggttttgt aaaatttaca
     1861 tttttaggtt ggtgctgtaa cagacagaca ctactaattg aggtgatatt aacaggcttc
     1921 taatgttaaa tgttgctatg gttacattgc cacatgatag ctagcaatgc cacaagatcc
     1981 cagcgaccac agcaagtctt agctgatgga ggctctgagc cctcgtttac taacagggta
     2041 tctaatgagt gtctgctgtg gctgtcacag agtacacatc acctgtgtca atcatctgtg
     2101 tttctaggtg gccacctgca gagcagcgtg actttctggt caccaggcct gtctcctggt
     2161 catacatttt acattaggtc tcactaagac aagcctgagg acgacctggt tctctcagta
     2221 cttgagtttc ccacttcgtc agtgactgtg agagtggctt tattctctaa cgcagagtca
     2281 gatgtataaa gatccatttt catatttaga acttagcagt tgctttgatg ccgttcagtt
     2341 tactatattg tcctggctaa atgtagttct ggttttcaga gagctgtaga tagaggacaa
     2401 gatatattaa cttcttaagt caacattttg tttgtgattt ttaaagtgca gtctccattt
     2461 tatacttaaa aaaaagcaat ttatatattt tgttacaagt cccagttagc acttcctgtg
     2521 catgcaggtg tcctttgttg ttgcaaccat atctatattg caccttttat tcagctgctt
     2581 tccaaaaatg ataccactca agaattgaat cttgaaatta tcaggcaggc tgcttcaaca
     2641 agggcattct gaacacttgg cttttgattt ctttatacaa acgtatgatg ctcctttttt
     2701 ctctaccttg gtatctgaaa aactaatttt gtatttccat ataactttgt aaatgccttt
     2761 tttttatttt aaagattaga tcctataaaa ggtaggttta ttggaaattg aggccattgg
     2821 gaagggtggg gggggagaaa gggcctgaac ataggaagga agaggagaag agaaaatgcc
     2881 tttcgtattt tatcaggaaa gtaaaaattt ccccaaaaac caaaaggatt ttgcattaag
     2941 acagcagtat tgcagacatg taatgagtgg atgaggggaa tgagcagttc gttcactcta
     3001 atcatctgtg tataaggcag ttatttcagt gggctggacc cgttcaccct gactggtaaa
     3061 tgcactccca aggtgggaag tgtcctttga gctccggtac aattgtgagg gaaacaaacg
     3121 ccttctttaa cagatgcacc tgagaggaca ggaagttctg ttggcacact gattgctttt
     3181 aatccagaag tgaaccctta aaaacttaca gtctcgtctt cgtatttttc attacagatg
     3241 cccatttggg gatggaatct gctttgacag ctagcaaagt gacacgctgt tcttgatgac
     3301 agcaattcag gggagacttg attaaaacaa ggtgaaacta ccaaggccag tgtattgcag
     3361 aaccgagagg cagcttgtct cgagtgacta gcgagaggag cgagcgtttg tcttggaggt
     3421 taaagcccac tgtaactggc tgttaggaac agggtgggta gttgtgaaaa gcacttttta
     3481 aaatggaata aatgttgaat gcttacatgg tcttaaccac tgtaaacacc aaataaacac
     3541 ttatttttac atta
//
