LOCUS       NM_001013202            3324 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus chloride channel accessory 5 (Clca5), mRNA.
ACCESSION   NM_001013202 XM_342354
VERSION     NM_001013202.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3324)
  AUTHORS   Yamazaki,J., Okamura,K., Uehara,K. and Hatta,M.
  TITLE     CLCA splicing isoform associated with adhesion through
            beta1-integrin and its scaffolding protein: specific expression in
            undifferentiated epithelial cells
  JOURNAL   J Biol Chem 288 (7), 4831-4843 (2013)
   PUBMED   23297403
  REMARK    GeneRIF: CLCA splicing isoform is associated with adhesion through
            beta1-integrin and its scaffolding protein
REFERENCE   2  (bases 1 to 3324)
  AUTHORS   Yamazaki,J., Okamura,K., Ishibashi,K. and Kitamura,K.
  TITLE     Characterization of CLCA protein expressed in ductal cells of rat
            salivary glands
  JOURNAL   Biochim Biophys Acta 1715 (2), 132-144 (2005)
   PUBMED   16137643
REFERENCE   3  (bases 1 to 3324)
  AUTHORS   Jeong,S.M., Park,H.K., Yoon,I.S., Lee,J.H., Kim,J.H., Jang,C.G.,
            Lee,C.J. and Nah,S.Y.
  TITLE     Cloning and expression of Ca2+-activated chloride channel from rat
            brain
  JOURNAL   Biochem Biophys Res Commun 334 (2), 569-576 (2005)
   PUBMED   16023076
  REMARK    GeneRIF: We successfully cloned a rat brain CLCA (rbCLCA).
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB119249.1.
            
            On Aug 30, 2012 this sequence version replaced NM_001013202.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB119249.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00155302,
                                           SAMD00155336 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3324              AB119249.1         2-3325
FEATURES             Location/Qualifiers
     source          1..3324
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..3324
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /note="chloride channel accessory 5"
                     /db_xref="GeneID:362052"
                     /db_xref="RGD:621100"
     exon            1..178
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..2731
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /note="chloride channel calcium activated 4;
                     Ca(2+)-activated chloride channel splicing; calcium
                     activated chloride channel; chloride channel calcium
                     activated 2"
                     /codon_start=1
                     /product="chloride channel accessory 5 precursor"
                     /protein_id="NP_001013220.1"
                     /db_xref="GeneID:362052"
                     /db_xref="RGD:621100"
                     /translation="MVPVLKVLLFLTLHLLQDTKSFKVHLNNNGYEGVVIAINPSVPE
                     DERLIPSLKEMVTQASTYLFEASQGRFYFRNVSILVPMTWKSKSEYLMPKRESYDKAD
                     VIVANSHLKYGDNPYTLQYGQCGDRGRYIHFTPNFLLTDNVRNYGPRGRVFVHEWAHL
                     RWGVFDEYNEDRPFYISGKNTIEVTRCSTDIKGSKAVHERQRGSDVTRLCRWDSRTGL
                     YEPKCKFFPDKIQTARASIMFMQNLNSVVEFCTEKTHNTEAPNLQNKICNGRSTWDVI
                     KESADFQQAPPMRGTEAPPPPTFSLLKSRQRVICLVLDKSGSMDTEDRLIRMNQAAEL
                     YLTQIVEKESMVGLVTFDSTAQIQNYLIKITNTGDYKKITGNLPQQAVGGTSICRGLE
                     AGFQAITSSDQSTSGSEIVLLTDGEDDLISSCFEVVKHSGAVIHTIALGPKAARELET
                     LSDMTGGLRFYANKDVNSLMDAFSGISSASGNLSQQALQLESKAFNIGGGTWINGTVP
                     VDSTIGNDTFFVITWTVQKPEIILRDPKRKKYTTSDFQDNKLNIRSARLQIPGTAETG
                     TWTYSLFNKGVKPQLLTVTVTTRARSPTTQPLMATAHMSQSTAQYPSPMIVYARVSQG
                     FLPVLGANVTAVIESENGSRVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKV
                     RVQARKSKARLSLRQKNKSLYIPGYVENGKIILNPPRPEVPEEATEAAVEDFSRLTSG
                     ESFTVSGAPPDGGHAHVFPPSKVTDLEAEFKGDHIHLTWTAPGKVLDKGRAHRYVIRM
                     SRHPPGLQDFNDATLVNTSGLIPKEAGSEETFKFKPASFKIENGTQLYIAILANNEAG
                     LTSEVSNIAQAVNFIPPEHSFSTLSPDISAICLTIWGLTVILNDILN"
     exon            179..319
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            320..467
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            468..576
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            577..754
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            755..982
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1207
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1385
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1486
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1711
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1982
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2150
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2390
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
     exon            2391..3310
                     /gene="Clca5"
                     /gene_synonym="CLCA; Clca2; Clca4; rbCLCA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caccatagca tgtgcgagca tggtgccagt gctgaaggtc cttctgttcc tcaccctgca
       61 cctcttgcag gacacaaaaa gcttcaaggt ccatctcaac aacaatggat atgagggtgt
      121 ggtcattgca attaacccca gtgtaccaga ggatgaaaga ctcatcccaa gcttaaagga
      181 aatggtcact caagcctcta cttacctgtt tgaagccagc caaggaaggt tttacttcag
      241 gaatgtaagc atattagtcc cgatgacctg gaagtcaaaa tctgagtact tgatgccaaa
      301 acgagaatca tatgacaaag cagatgtcat agttgccaat tctcatctga aatatggaga
      361 caatccctac acccttcaat atgggcagtg tggggacaga ggacggtaca tacatttcac
      421 tccaaacttc ctgctcactg ataacgtgcg taactatgga ccccgaggca gagtctttgt
      481 ccatgagtgg gctcatctcc ggtggggagt gtttgatgag tataatgagg accggccttt
      541 ctacatatct ggaaagaaca ctatcgaagt gacaaggtgt tctaccgaca tcaagggctc
      601 taaggcggtc catgagcgcc agagaggcag cgatgtgaca aggttatgcc gatgggactc
      661 gaggacaggg ctgtatgaac ccaaatgtaa atttttccca gacaaaattc agactgccag
      721 ggcctccata atgttcatgc aaaatctcaa ttccgtggtt gaattttgca cagaaaaaac
      781 ccataatacg gaagccccaa acctacaaaa caaaatatgc aatggcagaa gcacgtggga
      841 cgtaatcaag gagtccgctg actttcagca ggcccctccc atgagaggaa cagaagcccc
      901 tcctccaccc acgttttcct tgctcaagtc cagacagcga gtgatctgct tggtgctgga
      961 taaatccgga agcatggaca cagaagaccg ccttattcga atgaatcaag cagcggaact
     1021 gtacttaact caaattgttg aaaaggaatc tatggttgga ttagtcactt ttgacagcac
     1081 tgcccaaatc caaaattacc tgataaaaat aactaatacc ggtgactaca agaaaatcac
     1141 tggaaatctc cctcagcagg ctgttggggg gacttcaatc tgcaggggac tggaagcagg
     1201 atttcaggca attacctcca gtgaccagag tacttccggt tctgagattg tattgctaac
     1261 agatggggaa gatgatctaa taagttcatg ctttgaggtg gtcaaacaca gcggtgcggt
     1321 cattcacacc atcgccctgg ggcctaaagc tgcccgagaa ctggagactt tgtcggatat
     1381 gacaggaggg cttcgctttt atgccaacaa agatgtgaac agcctgatgg acgctttcag
     1441 tgggatttcc tctgcaagtg gcaacctctc ccagcaggct ctgcagttgg agagcaaagc
     1501 cttcaatatt ggagggggga catggataaa tggtacagta cctgtggaca gtaccattgg
     1561 caacgacact ttctttgtta ttacctggac agtccaaaag ccagaaatta ttcttcgaga
     1621 tccaaaaaga aaaaaatata caacctcaga tttccaagac aataaactaa acattcgatc
     1681 tgctcgactt caaataccag gcactgcaga gacaggaact tggacttaca gcctcttcaa
     1741 taagggggtc aaacctcagt tgctaactgt gacagtgacc actcgagcca gaagtcccac
     1801 cacacagccc ctcatggcca ccgctcacat gagtcagagc acagcccagt accctagtcc
     1861 gatgattgtg tatgcacggg tcagccaagg gtttttgcct gttctgggag ccaatgtcac
     1921 agccgtcata gaatctgaaa atggaagtcg agtcaccctg gagctctggg acaacggggc
     1981 aggtgctgac actgtcaaaa atgatggcat ctacacgaga tattttacag attatcacgg
     2041 aaatggtaga tacagcttaa aagtgcgtgt ccaggcaaga aagagcaaag ccagactaag
     2101 tttaagacaa aagaacaagt ctttatatat acctggctat gttgaaaatg gtaaaattat
     2161 actgaatcca cccagaccgg aagtcccaga agaagctaca gaagctgcag tggaagactt
     2221 cagcagacta acctctggag agtcgtttac tgtgtccgga gcgccccctg atggcggcca
     2281 cgctcatgtg ttcccaccca gtaaagttac agacctggag gccgagttta aaggtgatca
     2341 tattcacctt acctggacgg cccctggcaa ggttctcgat aaaggaagag cgcacagata
     2401 cgtcatcaga atgagccggc atcctcctgg tctccaagat tttaacgacg ctactttagt
     2461 gaatacttcc ggtctgatac ctaaagaggc tggctcagaa gaaacgttta aattcaaacc
     2521 agcaagtttt aaaatagaaa acggcaccca gctctacatt gcaattctgg ccaacaatga
     2581 agccggtctc acctctgagg tctccaacat cgcacaggct gtcaacttta ttcctccaga
     2641 acatagtttc tctacactca gccctgatat ttctgcaatc tgtctgacaa tttgggggtt
     2701 aactgtgatt cttaacgata ttttaaacta gaaaatatac taacactaaa gtccaatctt
     2761 gtacatattt gctaagtgtt tctttagaat gagtttacta aactcaatgt ctgcctgtca
     2821 acaattgtaa tatagaagtt catattcaaa gtcgggaatt ccctgagtta agtaacacca
     2881 attcttctgc tgtatgtaaa tcaagatgaa catttgctca tttggtctct taattgtccc
     2941 attcactgtg aaaataagac atctattccc ttttcacagt gtgaaacaag ttcacttttt
     3001 tttattaaca aaataaaaac gcatatgtca gtcaagagca attatgcata tattacagca
     3061 aatgatttta tagttgaatt atttgtaaga taattaataa agaatacttt ctgtttattc
     3121 aactgaaatc aaaagggact atgaaagaaa tttgtaaagg aaaatgttca aaagtagcca
     3181 tgagtcttat gtcttttgtc attgactgaa ggtgttttat gagtactccg cacaaaatga
     3241 tcgttgtaac ccttgcatct agagcaaaac ttgatatgta atagatattc aataaatgtt
     3301 tgttaaataa aaaaaaaaaa aaaa
//
