LOCUS       NM_201419               3097 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chloride channel accessory 4 (Clca4), mRNA.
ACCESSION   NM_201419 XM_342355 XM_342356
VERSION     NM_201419.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3097)
  AUTHORS   Song,J., Zhang,X., Qi,Z., Sun,G., Chi,S., Zhu,Z., Ren,J., Qiu,Z.,
            Liu,K., Myatt,L. and Ma,R.Z.
  TITLE     Cloning and characterization of a calcium-activated chloride
            channel in rat uterus
  JOURNAL   Biol Reprod 80 (4), 788-794 (2009)
   PUBMED   19144963
  REMARK    GeneRIF: The identification and characterization of rat Clca4 help
            decipher the contribution of Ca(2+)-activated Cl(-) conductance in
            myometrial contractility.
REFERENCE   2  (bases 1 to 3097)
  AUTHORS   Evans,S.R., Thoreson,W.B. and Beck,C.L.
  TITLE     Molecular and functional analyses of two new calcium-activated
            chloride channel family members from mouse eye and intestine
  JOURNAL   J Biol Chem 279 (40), 41792-41800 (2004)
   PUBMED   15284223
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY333961.1.
            
            On or before Jan 31, 2004 this sequence version replaced
            XM_342355.1, XM_342356.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY333961.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3097
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..3097
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /note="chloride channel accessory 4"
                     /db_xref="GeneID:362053"
                     /db_xref="RGD:1303234"
     exon            1..127
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            128..219
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            220..456
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..3066
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /note="chloride channel calcium activated 6 protein;
                     parturition-related protein PRP3; chloride channel,
                     calcium activated, family member 4; calcium-activated
                     chloride channel regulator 4; chloride channel calcium
                     activated 4"
                     /codon_start=1
                     /product="calcium-activated chloride channel regulator 4
                     precursor"
                     /protein_id="NP_958822.1"
                     /db_xref="GeneID:362053"
                     /db_xref="RGD:1303234"
                     /translation="MMGFSRGIVFLLLLYLLQGSDTSLVKLNENGYEDIIIAIDPAVS
                     EDVTIIDQIKDMVTKASAYLFEATEKRFFFKNVSILIPENWTNSDQYRRPKQESYKHA
                     DIKVAPPALQGRDEPYTRQFTKCGKKAEYIHFTPDFVLGRKQKEYGDSGRLLVHEWAH
                     LRWGVFDEYNEDQPFYSASSKKIEATRCSTGIKGMNKAQVCQGGSCITRNCRRNSTTQ
                     LYEKDCQFFPDKVQTEKSSIMFMQSIDSVTEFCKKENHNREAPTLHNQKCDYRSTWEV
                     ISNSEDFKNSTPMEMPPSPPFFSLLRISERIVCLVLDVSGSMGSYDRLNRMNQAAKFF
                     LQQILESRSWAGMVHFHSSATVKSELIQINSDVERNQLLETLPTSASGGTSICSGIRT
                     AFQVFKNKGYQTGGNDILLLSDGEDSTAKDCLDEVKDSGAVVHFIALGKAFDQSISNM
                     ANVTGGKQLFATDEAQNNGLIDAFGALASENADVTEKSLQLESKGAVLTNSRWLNDTV
                     VIDSTVGKDTYFLVTWSQQAPAIHLRDPKGTQITNFTIDTASKMAYLTIPGIAEVGVW
                     TYNLEAKVDSEILTITVTSRASRPSVPPIIVNAKVNTDTNSFPSPMIVYAEVLQGYTP
                     IIGARVTATIESNSGKTEELVLLDNGAGADAFKDDGVYSRYFTAYSDNGRYSVKVRAD
                     GGTNSARRSSRHPSSRAAYIPGWVVDGEIQGNPPRPETTEDTQPVLENFSRTASGGAF
                     VMSKVPALPLPDQYPPNQITDLQATLDGEKISLTWTAPGDDFDVGRVQQYIIRTSENI
                     IDLRDNFNKSLQVNTTHLIPKEANSKETFAFKPETISGENATYIFIAIESVDKSNLHS
                     GLSNIAQVALFTPQADPVPEESPQSGVSITTIVLSVVGAVVLVCIIVSTTVCILKRKR
                     SSSGPATTF"
     exon            457..597
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            598..745
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            746..854
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1032
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1251
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1479
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1657
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1764
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1980
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2248
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2419
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2420..2653
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..3097
                     /gene="Clca4"
                     /gene_synonym="Clca6; Prp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtacctcc cacctcgatg tgaccaagca tatcctaagc aactttctgt actgacatga
       61 gtgaaaatat gtgatgttat cttacacgaa cacagcctca gcattccagg aagttgtcct
      121 tgggcagagc cataaaccaa tgctgcgctc agccaagctc agagaagcct tcctttgcac
      181 ggactagaga gaatgcagag accgtggcta ctaacagtgc aagcaggtga tttttaggcg
      241 tatatataca cctgacaaga gacacagaga aagaaaggct gcgacgaggc cggaatgatg
      301 gggttctcca gagggattgt tttcctcctg ctcctgtacc tgcttcaggg gtcagacacc
      361 tccttggtaa agctgaatga gaatggttat gaagacatta ttattgccat cgatcctgct
      421 gtgtccgaag atgtaacaat aattgaccaa ataaaggaca tggtgactaa agcatctgca
      481 tacctttttg aagctacaga aaaaagattt tttttcaaaa acgtctctat attaattcct
      541 gagaattgga caaacagtga ccagtacagg aggccaaagc aggaaagcta caaacatgct
      601 gacattaaag ttgcacctcc tgctctccag ggcagggatg agccctacac ccggcagttc
      661 acaaagtgtg gaaagaaagc tgaatacatc cacttcaccc ccgactttgt attggggaga
      721 aaacaaaagg aatatggaga ttcaggaaga ctgttggtcc atgaatgggc ccatcttcgc
      781 tggggagtat ttgatgagta caacgaagac cagccattct acagtgcttc atcaaagaaa
      841 atcgaagcaa caaggtgttc cacaggtatc aagggtatga ataaagccca ggtatgccaa
      901 gggggcagct gtataaccag aaattgcaga cggaattcca ccacacagtt atatgaaaaa
      961 gattgtcagt tcttcccgga taaagttcaa acagaaaagt catctataat gttcatgcaa
     1021 agtatcgatt cagtgactga attctgtaaa aaagaaaacc ataatcgaga ggctccaact
     1081 ctacataatc agaagtgcga ttacagaagc acatgggaag taatcagtaa ttctgaggat
     1141 tttaaaaaca gcacacccat ggagatgcca ccctctccac ccttcttctc gctgctgagg
     1201 atcagtgaaa gaattgtgtg cctagtgctt gatgtgtctg ggagcatggg gtcttatgat
     1261 cgcctcaatc gaatgaacca agcagcaaaa ttcttcctac agcagatact tgaaagtagg
     1321 tcctgggcag ggatggtaca ctttcatagc tcggccactg ttaagagtga gctgatccaa
     1381 ataaacagtg atgtcgagag aaaccagctt ttggaaacct tacctacaag tgctagcgga
     1441 gggacatcca tctgctctgg aatcagaact gcatttcagg tatttaaaaa taaaggatac
     1501 caaactggtg ggaatgacat cttgctgttg agcgatgggg aggacagcac agccaaagac
     1561 tgccttgatg aggtgaaaga cagcggggcc gtagttcatt tcattgcctt gggaaaagca
     1621 tttgatcaat ctatatcaaa catggccaac gtaacaggtg gaaagcaact gtttgctaca
     1681 gatgaagccc agaacaatgg actcattgat gctttcgggg ccctggcttc agaaaatgct
     1741 gatgtcactg agaagtccct tcagcttgaa agcaagggtg ctgtgttgac caacagtcgc
     1801 tggctgaacg acactgtcgt tattgacagc accgtgggaa aggacacata ctttcttgtc
     1861 acctggagcc aacaagcccc tgccattcat ctcagggatc ccaaaggaac acaaataaca
     1921 aatttcacaa tcgacacggc ttccaaaatg gcctatctca ctatcccagg aattgctgag
     1981 gtcggcgttt ggacttacaa ccttgaagcc aaagtagact cagagatact aacaattaca
     2041 gtaacttctc gggcatcacg tccttctgtg ccacccatca ttgtaaatgc aaaagttaac
     2101 acagacacga acagtttccc cagtccaatg attgtgtatg cagaagttct acaaggttac
     2161 actcccatca ttggagcacg cgtgacagct accatagaat caaatagtgg aaaaacagaa
     2221 gagctagtac tgctggacaa tggtgcaggg gctgatgctt tcaaggatga cggggtctac
     2281 tccaggtact tcacggctta ttcagataat ggcagatata gcgtaaaggt ccgcgcagac
     2341 ggaggaacaa actctgcccg gagaagttca cggcatccgt ccagcagagc ggcatacata
     2401 ccaggctggg tagtggatgg agaaattcaa gggaacccac ccagacctga aactactgag
     2461 gacactcagc ccgtcctgga gaatttcagc aggacggcat ctggaggtgc ctttgtgatg
     2521 tccaaggtcc cagctcttcc attgcctgat cagtacccac caaatcaaat cacagacctc
     2581 caggccacac ttgatgggga aaagatcagt ctaacatgga cggcaccagg agatgacttt
     2641 gatgttggaa gagttcaaca gtatatcata agaacaagtg aaaatatcat tgacctcaga
     2701 gacaatttta ataagtctct tcaggttaat acaactcacc tgataccaaa agaagccaac
     2761 tccaaggaaa cctttgcctt taaaccagaa actatctcag gagaaaacgc aacctacata
     2821 ttcattgcca ttgaaagtgt cgacaaaagc aatttgcact ccggactgtc caacatcgca
     2881 caagtagcac tgttcacccc tcaggcagat cctgtccctg aggaaagtcc ccagtctgga
     2941 gttagtatca ctacgattgt gctgtctgtg gtgggcgccg ttgtactagt ttgtatcatt
     3001 gtaagtacca ctgtttgtat cttaaagaga aaaaggtcct cctcagggcc tgcaacaaca
     3061 ttttaaaaag caacatcagg gctggagaga tggctca
//
