LOCUS       NM_001108740            2548 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus cytoskeleton-associated protein 4 (Ckap4), mRNA.
ACCESSION   NM_001108740 XM_001079545 XM_343189
VERSION     NM_001108740.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2548)
  AUTHORS   Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L and Du
            R.
  TITLE     Significant Down-Regulation of Urea Cycle Generates Clinically
            Relevant Proteomic Signature in Hepatocellular Carcinoma Patients
            with Macrovascular Invasion
  JOURNAL   J Proteome Res 18 (5), 2032-2044 (2019)
   PUBMED   30901224
REFERENCE   2  (bases 1 to 2548)
  AUTHORS   Zhang C, Kho YS, Wang Z, Chiang YT, Ng GK, Shaw PC, Wang Y and Qi
            RZ.
  TITLE     Transmembrane and coiled-coil domain family 1 is a novel protein of
            the endoplasmic reticulum
  JOURNAL   PLoS One 9 (1), e85206 (2014)
   PUBMED   24454821
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2548)
  AUTHORS   Zanivan S, Maione F, Hein MY, Hernandez-Fernaud JR, Ostasiewicz P,
            Giraudo E and Mann M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   4  (bases 1 to 2548)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 2548)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 2548)
  AUTHORS   Kazi AS, Tao JQ, Feinstein SI, Zhang L, Fisher AB and Bates SR.
  TITLE     Role of the PI3-kinase signaling pathway in trafficking of the
            surfactant protein A receptor P63 (CKAP4) on type II pneumocytes
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 299 (6), L794-L807 (2010)
   PUBMED   20870746
  REMARK    GeneRIF: Data demonstrate an important role for the PI3-kinase-Akt
            pathway in intracellular transport of surfactant protein A receptor
            P63.
REFERENCE   7  (bases 1 to 2548)
  AUTHORS   Iinuma T, Aoki T, Arasaki K, Hirose H, Yamamoto A, Samata R, Hauri
            HP, Arimitsu N, Tagaya M and Tani K.
  TITLE     Role of syntaxin 18 in the organization of endoplasmic reticulum
            subdomains
  JOURNAL   J Cell Sci 122 (Pt 10), 1680-1690 (2009)
   PUBMED   19401338
REFERENCE   8  (bases 1 to 2548)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   9  (bases 1 to 2548)
  AUTHORS   Nichols RJ and Traktman P.
  TITLE     Characterization of three paralogous members of the Mammalian
            vaccinia related kinase family
  JOURNAL   J Biol Chem 279 (9), 7934-7946 (2004)
   PUBMED   14645249
REFERENCE   10 (bases 1 to 2548)
  AUTHORS   Fujimoto Y, Itabe H, Sakai J, Makita M, Noda J, Mori M, Higashi Y,
            Kojima S and Takano T.
  TITLE     Identification of major proteins in the lipid droplet-enriched
            fraction isolated from the human hepatocyte cell line HuH7
  JOURNAL   Biochim Biophys Acta 1644 (1), 47-59 (2004)
   PUBMED   14741744
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079545.1, XM_343189.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV773851.1, EX491027.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2548
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..2548
                     /gene="Ckap4"
                     /note="cytoskeleton-associated protein 4"
                     /db_xref="GeneID:362859"
                     /db_xref="RGD:1311989"
     exon            1..177
                     /gene="Ckap4"
                     /inference="alignment:Splign:2.1.0"
     exon            178..2548
                     /gene="Ckap4"
                     /inference="alignment:Splign:2.1.0"
     CDS             505..1485
                     /gene="Ckap4"
                     /codon_start=1
                     /product="cytoskeleton-associated protein 4"
                     /protein_id="NP_001102210.1"
                     /db_xref="GeneID:362859"
                     /db_xref="RGD:1311989"
                     /translation="MKVASLEESKGDRSQDVKVLKEAVKEVQASMKSRERDIEALKSS
                     LQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLQSEESSSRLPEDIR
                     RLEEELQQLKVGAHGSEEAVVFRDSKAFDELQKQMEGLGARLQYVEDGVYSMQVASAS
                     HTESLESLLSKSQEYEQRLAMLQEHVESLGPISDLASTVRSLEETQLALSSDLKGLKQ
                     GLGELPGTVESLQEQVHLLLSQDPAQAAGLPPQDFLDRLSSLDNLKSSVSQVESDLKM
                     LRTAVDSLVAYSVKIETNENSLESAKGLLDDLRNDLDRLFVKVEKIHEKI"
ORIGIN      
        1 aggcttggcc ggctgctcaa ctttctcttc tacctctccc tggtggcggc ggccgccttc
       61 tccggctggt atgtccatca cgtcctggaa gaggtccagc aggtccggcg tggccaccag
      121 gacttctccc gtcagaggga tgagctgggc cagggcttgc agggcgtcga gcagaaggta
      181 cagtctctgc aagccgcagt cgggaccttc gagtccatcc tgagaagttc ccagcataaa
      241 caggatctca cagagaaagc cgtgaaggaa ggggagagtg agatcaaccg tattagtgaa
      301 gttctacaga agctgcagaa tgagattctc aaagacctgt cggacgggat ccacgtggtg
      361 aaggatgccc gagagcggga cttcacgtcc ctggagaaca cggtcgagga gcgtctgacg
      421 gagctcacca agtccatcaa tgacaacatc gccatcttca ccgacgtaca gaaaaggagc
      481 cagaaggaga taaatgaggt caagatgaag gttgcctcct tggaagaatc caagggggac
      541 cgcagtcagg acgtgaaagt cctgaaggaa gccgtgaagg aggtgcaggc ctccatgaag
      601 tctcgagaga gggacatcga ggccctcaag agttcccttc agaccatgga gtccgatgtc
      661 tacacagagg tccgggagct agtgagcctg aagcaggagc agcaggcatt caagcaggcg
      721 gccgactcag agcgcctggc tctgcaggcc ctcacggaga agcttctgca gtccgaagag
      781 tcctcctctc gtctcccaga ggacatcagg agactggagg aagagctgca gcagctgaag
      841 gtgggagccc acgggtcaga ggaggccgtg gtcttcagag actcgaaagc cttcgacgaa
      901 ctccagaagc agatggaggg cctaggcgcc aggctccagt atgtagagga cggggtctac
      961 tcgatgcagg tggcttctgc gagccacact gagagcctgg agtcgctcct gtccaagagc
     1021 caggagtacg agcaacgcct ggccatgctg caggagcacg tagaaagcct ggggcctatc
     1081 tctgacctgg ccagcacggt gaggagcctg gaggagaccc agctggcgct ctccagcgac
     1141 ttgaaggggc tgaagcaagg cttgggtgag ctgccaggga ctgtggagtc gctgcaggag
     1201 caagtgcatt tgctgctcag ccaggaccca gcccaggccg cgggcttgcc tcctcaggac
     1261 ttcctggata gactctcctc tctagacaac ctgaaatcct cagtaagcca agtggaatca
     1321 gacttgaaaa tgctcaggac ggctgtggac agtttggttg cctactctgt taaaatcgaa
     1381 acgaacgaga atagcttaga gtccgccaag ggcctgctgg acgaccttcg gaatgatctg
     1441 gataggttgt tcgtgaaagt cgagaagatc catgaaaaga tctgaacgaa ccgggtgtgt
     1501 gggcccactt tcttacgacc aaaaaaacaa aacaaaacaa aaaaaaccca ttgtttcctc
     1561 ccaggtgccc tccccgccac cttctcggcc ctgccccacc ccatggagag cagcagacac
     1621 cagctgaagg tgttccggct ctggttaatt tgtgtgcaga tattaccaca tgcctttggt
     1681 ttcttaagtc ctgtttctgc ttttggttag gcttcctgaa ggcccagccc tgtgcagaaa
     1741 aggatgggtc tcctgctagg aagatgatgg ctgtggcttt aactggggat tatcaggaag
     1801 cagattaacc ttaaaaaaaa aaaatcctgt caggctgaca gatttatagt aaaatagaaa
     1861 aaaacaacaa agaacaggtg gggggcacgt tttttttagt ctttaaagaa aattaatttt
     1921 attgtttttt tttttatact cctagccagg gtttttatga gctggccctt aacttgtctt
     1981 ccatttagaa ctggtaaaaa ctcgtagatg tcagctctga atgggtgaaa gaggcccccc
     2041 tcccccaacc tgcctgaggg tcactttcag aagcatggtg tctctgtctc tctctctctc
     2101 tctctctcta atctagtcat aaggtaacta tgcaaatgtg tcaccaggct aggctgggtc
     2161 accaagtaaa tttgggaccc tagaggggga ggttcttcgg gttctgatgt gagagctgtc
     2221 ttttccacaa aggattcggg catcaccctg ggagatggag gccaggcctt tttgttttat
     2281 cacaggacct ctggagaggt ctctgcccct gtctgtcagt gaggatcacg tgtgctgcat
     2341 gtgttctcac tgtaccctcg cccctttgag aggtattgtc tttaatgact gccttgccct
     2401 tcccaccccc caccccccaa aaaaagaaaa aaagaaaaaa actgaaaaga aaaacaaagt
     2461 ttgttagttt actgtgaaat gaactgtatg gcttatttac agtattttta attcttaata
     2521 aacacttgag ctttgttatg atcttcag
//
