LOCUS       NM_001007799            1931 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus corepressor interacting with RBPJ, 1 (Cir1),
            mRNA.
ACCESSION   NM_001007799 XM_342448
VERSION     NM_001007799.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1931)
  AUTHORS   Vaz Meirelles,G., Ferreira Lanza,D.C., da Silva,J.C., Santana
            Bernachi,J., Paes Leme,A.F. and Kobarg,J.
  TITLE     Characterization of hNek6 interactome reveals an important role for
            its short N-terminal domain and colocalization with proteins at the
            centrosome
  JOURNAL   J Proteome Res 9 (12), 6298-6316 (2010)
   PUBMED   20873783
REFERENCE   3  (bases 1 to 1931)
  AUTHORS   Maita,H., Kitaura,H., Ariga,H. and Iguchi-Ariga,S.M.
  TITLE     CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative
            splicing
  JOURNAL   Exp Cell Res 303 (2), 375-387 (2005)
   PUBMED   15652350
REFERENCE   4  (bases 1 to 1931)
  AUTHORS   Hsieh,J.J., Zhou,S., Chen,L., Young,D.B. and Hayward,S.D.
  TITLE     CIR, a corepressor linking the DNA binding factor CBF1 to the
            histone deacetylase complex
  JOURNAL   Proc Natl Acad Sci U S A 96 (1), 23-28 (1999)
   PUBMED   9874765
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 8, 2022 this sequence version replaced NM_001007799.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085869.1, DY310848.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               JAXUCZ010000003.1  78596158-78596309   c
            153-247             JAXUCZ010000003.1  78592980-78593074   c
            248-321             JAXUCZ010000003.1  78589665-78589738   c
            322-332             JAXUCZ010000003.1  78589036-78589046   c
            333-397             JAXUCZ010000003.1  78588879-78588943   c
            398-446             JAXUCZ010000003.1  78588504-78588552   c
            447-564             JAXUCZ010000003.1  78586846-78586963   c
            565-671             JAXUCZ010000003.1  78570206-78570312   c
            672-757             JAXUCZ010000003.1  78568944-78569029   c
            758-1931            JAXUCZ010000003.1  78566438-78567611   c
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..1931
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /note="corepressor interacting with RBPJ, 1"
                     /db_xref="GeneID:362149"
                     /db_xref="RGD:1309199"
     exon            1..152
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1436
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /note="CBF1-interacting corepressor; CBF1 (RBPJ)
                     interacting corepressor 1; corepressor interacting with
                     RBPJ, CIR1"
                     /codon_start=1
                     /product="corepressor interacting with RBPJ 1"
                     /protein_id="NP_001007800.1"
                     /db_xref="GeneID:362149"
                     /db_xref="RGD:1309199"
                     /translation="MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQ
                     QYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGVKKENKEKEETEGETEYKFEWQKGA
                     PREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDG
                     SGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQDYVASDGEEDPEVEFLKSLTT
                     KQKQKLLRKLDRLEKKKKKKKSDKKKKKLQKSKNKHKKHKKSSSSSSSSSSSSSSSSS
                     SSSSSSSSSTSSSETDSSSESDNKEKKEKEKRKKRKKTKCSGNKSGDCKEYKSKNMLY
                     EELSSSHSDRGKAQEKLRLLKQESSGENSTWVHSGSDRKSRSHQHSPERKGSDRNGGS
                     RSRSRAEGSRRSRSRSPCGQKHREREARSRPHQSPSEEQKGRKGTRSHGDSEHRRERA
                     R"
     exon            153..247
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            248..321
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            322..332
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            333..397
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            398..446
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            447..564
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            565..671
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            672..757
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
     exon            758..1931
                     /gene="Cir1"
                     /gene_synonym="1700023b02rik; Cir; RGD1309199"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacagttccg gtgacgctcc gggagtttgt ttacgttcct cacagactta gcagttggct
       61 tctctggctc agactccaag atggggaagt cattcgccaa tttcatgtgt aaaaaggact
      121 ttcatcctgc ttccaaatcc aacatcaaga aggtatggat ggcagaacag aaaatatcat
      181 atgataaaaa gaaacaagaa gaattaatgc aacagtacct taaagaacaa gagtcatatg
      241 ataacagatt gcttatggga gatgagcgtg taaagaacgg cctgaatttc atgtatgaag
      301 ccccgccagg agttaaaaaa gaaaacaaag agaaagaaga aacggaagga gagacagaat
      361 acaagttcga atggcagaaa ggtgctccaa gggaaaaata tgctaaagat gacatgaaca
      421 tcagagatca gccctttggt attcaggttc gaaatgtaag gtgtattaaa tgtcacaagt
      481 ggggccatgt gaacacagat cgagagtgcc ccttgtttgg tctttccggg atcaatgcaa
      541 gttcagttcc tactgatggc tcagggccgt cgatgcaccc ctcggagcta atagcggaga
      601 tgagaaacag tgggtttgca ctgaaacgaa atgtactggg gagaaacttg accgcaaatg
      661 atccatcgca ggactatgtc gcaagtgacg gtgaagaaga ccctgaagtt gagttcttaa
      721 agtcgctcac caccaaacag aagcagaagc ttctcaggaa attggataga cttgaaaaga
      781 aaaaaaagaa aaagaaaagt gataagaaaa agaagaagtt acagaagagc aaaaataaac
      841 acaaaaaaca taaaaaatcc tcctcttcct catcttcttc ctcctcctcc tcctcttctt
      901 cctcctcctc ttcctcttcc tcttcctcat cctccacctc ctcctcggag acagatagca
      961 gcagtgagag tgacaacaaa gaaaagaaag agaaagagaa gaggaagaaa aggaagaaaa
     1021 ccaagtgttc tggaaataaa tccggtgact gtaaagagta caagtctaag aacatgcttt
     1081 atgaagaact ttctagcagc catagtgaca gggggaaagc ccaggaaaaa ttaaggcttc
     1141 taaaacaaga gagttctgga gaaaatagca catgggtcca ttctggttct gaccggaagt
     1201 ccagaagcca ccagcacagt ccagagagga aagggtctga cagaaacggg ggaagccgaa
     1261 gccgtagccg ggctgagggc agcaggcgaa gccggagcag gagtccttgc ggtcagaagc
     1321 acagggaaag ggaggcgagg agccggcccc accagagccc tagtgaggag cagaagggga
     1381 gaaagggcac ccgaagccat ggtgacagcg agcatagaag agagcgtgcg cgctgagcac
     1441 ccaagagata cagagagcgg caggttcaac agagctcggg aggaaccacc tgggcatcaa
     1501 gaacatcttt agcaagggct gatgtacaca ttgttatcta ataaaaagtc agttcatttc
     1561 catctctgaa aagtgtcctg tcaaatatta aagaacctgt gtgccgcagg cttaaacttt
     1621 cacatccttg cggggttatt tagggaatat tagtgctgtg gttttcggtt tgttgttgtt
     1681 gttattgttg tctttcttat tgctagttgt ttcttttgcc ttgtaccaga tttaaaatat
     1741 gtaagtaatt ctgtgctttt gttgttgttt tgaaatacca ttaaaacagt ggcagaatct
     1801 tgaatgatta tcaattcaaa tttgttatta taagatacaa atttgcttga agcaaaatgt
     1861 aatcattgtt gaaattgact agggtgaata aaacactgga taccaatcag cgtttcctta
     1921 agactttaaa a
//
