LOCUS       NM_001399449            1192 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus cell death-inducing DFFA-like effector b (Cideb),
            mRNA.
ACCESSION   NM_001399449 XM_006252002
VERSION     NM_001399449.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Cote,I., Chapados,N.A. and Lavoie,J.M.
  TITLE     Impaired VLDL assembly: a novel mechanism contributing to hepatic
            lipid accumulation following ovariectomy and
            high-fat/high-cholesterol diets?
  JOURNAL   Br J Nutr 112 (10), 1592-1600 (2014)
   PUBMED   25263431
REFERENCE   2  (bases 1 to 1192)
  AUTHORS   Tiwari,S., Siddiqi,S. and Siddiqi,S.A.
  TITLE     CideB protein is required for the biogenesis of very low density
            lipoprotein (VLDL) transport vesicle
  JOURNAL   J Biol Chem 288 (7), 5157-5165 (2013)
   PUBMED   23297397
  REMARK    GeneRIF: CideB protein is required for the biogenesis of very low
            density lipoprotein (VLDL) transport vesicle
REFERENCE   3  (bases 1 to 1192)
  AUTHORS   Erdtmann,L., Franck,N., Lerat,H., Le Seyec,J., Gilot,D., Cannie,I.,
            Gripon,P., Hibner,U. and Guguen-Guillouzo,C.
  TITLE     The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced
            apoptosis
  JOURNAL   J Biol Chem 278 (20), 18256-18264 (2003)
   PUBMED   12595532
REFERENCE   4  (bases 1 to 1192)
  AUTHORS   Liang,L., Zhao,M., Xu,Z., Yokoyama,K.K. and Li,T.
  TITLE     Molecular cloning and characterization of CIDE-3, a novel member of
            the cell-death-inducing DNA-fragmentation-factor (DFF45)-like
            effector family
  JOURNAL   Biochem J 370 (Pt 1), 195-203 (2003)
   PUBMED   12429024
REFERENCE   5  (bases 1 to 1192)
  AUTHORS   Inohara,N., Koseki,T., Chen,S., Wu,X. and Nunez,G.
  TITLE     CIDE, a novel family of cell death activators with homology to the
            45 kDa subunit of the DNA fragmentation factor
  JOURNAL   EMBO J 17 (9), 2526-2533 (1998)
   PUBMED   9564035
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jan 7, 2022 this sequence version replaced XM_006252002.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EX491921.1, SRR26643287.31502.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                JAXUCZ010000015.1  33226314-33226407   c
            95-239              JAXUCZ010000015.1  33225928-33226072   c
            240-386             JAXUCZ010000015.1  33223334-33223480   c
            387-577             JAXUCZ010000015.1  33222922-33223112   c
            578-1192            JAXUCZ010000015.1  33222135-33222749   c
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p13"
     gene            1..1192
                     /gene="Cideb"
                     /note="cell death-inducing DFFA-like effector b"
                     /db_xref="GeneID:364388"
                     /db_xref="RGD:1310000"
     exon            1..94
                     /gene="Cideb"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..713
                     /gene="Cideb"
                     /note="cell death activator CIDE-B; cell death-inducing
                     DNA fragmentation factor, alpha subunit-like effector B"
                     /codon_start=1
                     /product="lipid transferase CIDEB"
                     /protein_id="NP_001386378.1"
                     /db_xref="GeneID:364388"
                     /db_xref="RGD:1310000"
                     /translation="MEYLSALSSNGLLRSVSTMSSELSRRVWNSAPPPQRPFRVCDHK
                     RTVRKGLTAATRQELLDKVVETLLLSGVLTLVLEEDGTAVETEDFFELLEDDTCLMAL
                     EQGQSWSPKSGMLSYGLGREKPKHSKDIARITFDVYKQNPRDLFGSLNVKATFYGLYS
                     MSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHRQSHLH
                     S"
     exon            95..239
                     /gene="Cideb"
                     /inference="alignment:Splign:2.1.0"
     exon            240..386
                     /gene="Cideb"
                     /inference="alignment:Splign:2.1.0"
     exon            387..577
                     /gene="Cideb"
                     /inference="alignment:Splign:2.1.0"
     exon            578..1192
                     /gene="Cideb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagtgcccag ccccgaagca ataggggggc gactcgccgt ctctcaccca gccatggaat
       61 acctttcagc cttgagctcc aatggcctgc taaggtcagt gtctactatg agctccgagc
      121 ttagccgtag ggtctggaac tcggctcctc cacctcagcg acccttccgt gtctgtgatc
      181 ataagcggac agtccggaaa ggactaacag ccgccacccg ccaggaactg ctagataagg
      241 tagtggagac cttgctgcta agcggagtgc taacgctggt cctggaggag gatgggactg
      301 cggtggagac tgaagacttc ttcgagctgc tagaggatga cacatgcttg atggctctag
      361 agcagggaca gagctggagc ccaaagagtg ggatgttgtc atacggccta ggacgggaga
      421 agccaaaaca tagcaaggac atcgcccgca tcacctttga tgtgtataag caaaatcctc
      481 gagacctctt cggcagcctc aacgtgaaag ctacattcta cgggctctac tccatgagct
      541 gcgattttca aggagttggc cctaaaaaag tactcaggga gctccttcgt tggacttcct
      601 cactgctgca aggcctgggc catatgctgc tgggaatctc atctactctg cgccatgtgg
      661 tggagggggc tgagcgatgg cagtggcacc ggcagagtca cctccattca taatgaaatt
      721 gtgctttgag cctgtgttga aagactggtt ccggggttgg ggatttagct cagtggtaga
      781 gcgcttgcct aggaagcgca aggccctagg ttcagtcccc agctccgaag gaaaaaaaaa
      841 aaaaaaaaag aaagactggt tccatgtgcc acgtgagggg cattaaaggg catcttcagg
      901 tctgggtctg cggtgtaccc taggtaacta agctgactcc aacagatcag cccactgccc
      961 tggtgctcca gcctgtacat tttcctgaag aacgataccc atcttcccta cctccctgcc
     1021 ttccactcac cctacagaac cacacccttg tcccctggca tcctgatctc accatacctg
     1081 ctgcttcatc taggttctca ctgactccta tccctgcata ccaatgacaa ctggccctag
     1141 ctttacctca ggatatcttt cccctaaaaa ataaaaatat ttccaagaaa aa
//
