LOCUS       NM_031145                836 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus calcium and integrin binding 1 (Cib1), mRNA.
ACCESSION   NM_031145
VERSION     NM_031145.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   de Jong,S.J., Crequer,A., Matos,I., Hum,D., Gunasekharan,V.,
            Lorenzo,L., Jabot-Hanin,F., Imahorn,E., Arias,A.A., Vahidnezhad,H.,
            Youssefian,L., Markle,J.G., Patin,E., D'Amico,A., Wang,C.Q.F.,
            Full,F., Ensser,A., Leisner,T.M., Parise,L.V., Bouaziz,M.,
            Maya,N.P., Cadena,X.R., Saka,B., Saeidian,A.H., Aghazadeh,N.,
            Zeinali,S., Itin,P., Krueger,J.G., Laimins,L., Abel,L., Fuchs,E.,
            Uitto,J., Franco,J.L., Burger,B., Orth,G., Jouanguy,E. and
            Casanova,J.L.
  TITLE     The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic
            immunity to beta-papillomaviruses
  JOURNAL   J Exp Med 215 (9), 2289-2310 (2018)
   PUBMED   30068544
REFERENCE   2  (bases 1 to 836)
  AUTHORS   Czeredys,M., Gruszczynska-Biegala,J., Schacht,T., Methner,A. and
            Kuznicki,J.
  TITLE     Expression of genes encoding the calcium signalosome in cellular
            and transgenic models of Huntington's disease
  JOURNAL   Front Mol Neurosci 6, 42 (2013)
   PUBMED   24324398
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 836)
  AUTHORS   Kostyak,J.C., Naik,M.U. and Naik,U.P.
  TITLE     Calcium- and integrin-binding protein 1 regulates megakaryocyte
            ploidy, adhesion, and migration
  JOURNAL   Blood 119 (3), 838-846 (2012)
   PUBMED   22128142
REFERENCE   4  (bases 1 to 836)
  AUTHORS   Sobczak,A., Debowska,K., Blazejczyk,M., Kreutz,M.R., Kuznicki,J.
            and Wojda,U.
  TITLE     Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite
            outgrowth
  JOURNAL   Biochim Biophys Acta 1813 (5), 1025-1037 (2011)
   PUBMED   21215777
  REMARK    GeneRIF: CaMy1 via SCG10 couples Ca(2+) signals with the dynamics
            of microtubules during neuronal outgrowth in the developing brain.
REFERENCE   5  (bases 1 to 836)
  AUTHORS   Kostyak,J.C. and Naik,U.P.
  TITLE     Calcium- and integrin-binding protein 1 regulates endomitosis and
            its interaction with Polo-like kinase 3 is enhanced in endomitotic
            Dami cells
  JOURNAL   PLoS One 6 (1), e14513 (2011)
   PUBMED   21264284
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 836)
  AUTHORS   Zhu,J., Stabler,S.M., Ames,J.B., Baskakov,I. and Monteiro,M.J.
  TITLE     Calcium binding sequences in calmyrin regulates interaction with
            presenilin-2
  JOURNAL   Exp Cell Res 300 (2), 440-454 (2004)
   PUBMED   15475008
REFERENCE   7  (bases 1 to 836)
  AUTHORS   Henderson,M.J., Russell,A.J., Hird,S., Munoz,M., Clancy,J.L.,
            Lehrbach,G.M., Calanni,S.T., Jans,D.A., Sutherland,R.L. and
            Watts,C.K.
  TITLE     EDD, the human hyperplastic discs protein, has a role in
            progesterone receptor coactivation and potential involvement in DNA
            damage response
  JOURNAL   J Biol Chem 277 (29), 26468-26478 (2002)
   PUBMED   12011095
REFERENCE   8  (bases 1 to 836)
  AUTHORS   Haataja,L., Kaartinen,V., Groffen,J. and Heisterkamp,N.
  TITLE     The small GTPase Rac3 interacts with the integrin-binding protein
            CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and
            spreading
  JOURNAL   J Biol Chem 277 (10), 8321-8328 (2002)
   PUBMED   11756406
REFERENCE   9  (bases 1 to 836)
  AUTHORS   Kauselmann,G., Weiler,M., Wulff,P., Jessberger,S., Konietzko,U.,
            Scafidi,J., Staubli,U., Bereiter-Hahn,J., Strebhardt,K. and Kuhl,D.
  TITLE     The polo-like protein kinases Fnk and Snk associate with a Ca(2+)-
            and integrin-binding protein and are regulated dynamically with
            synaptic plasticity
  JOURNAL   EMBO J 18 (20), 5528-5539 (1999)
   PUBMED   10523297
REFERENCE   10 (bases 1 to 836)
  AUTHORS   Stabler,S.M., Ostrowski,L.L., Janicki,S.M. and Monteiro,M.J.
  TITLE     A myristoylated calcium-binding protein that preferentially
            interacts with the Alzheimer's disease presenilin 2 protein
  JOURNAL   J Cell Biol 145 (6), 1277-1292 (1999)
   PUBMED   10366599
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 25, 2020 this sequence version replaced NM_031145.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091143.1, AF136585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                JAXUCZ010000001.1  143593019-143593115 c
            98-132              JAXUCZ010000001.1  143592854-143592888 c
            133-241             JAXUCZ010000001.1  143590774-143590882 c
            242-392             JAXUCZ010000001.1  143589024-143589174 c
            393-511             JAXUCZ010000001.1  143588789-143588907 c
            512-600             JAXUCZ010000001.1  143588621-143588709 c
            601-836             JAXUCZ010000001.1  143587591-143587826 c
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..836
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /note="calcium and integrin binding 1"
                     /db_xref="GeneID:81823"
                     /db_xref="RGD:620133"
     exon            1..97
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..622
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /note="KIP; calmyrin; kinase-interacting protein;
                     DNA-PKcs-interacting protein; calcium- and
                     integrin-binding protein"
                     /codon_start=1
                     /product="calcium and integrin-binding protein 1"
                     /protein_id="NP_112407.1"
                     /db_xref="GeneID:81823"
                     /db_xref="RGD:620133"
                     /translation="MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPPEHRT
                     VEESLHTRVSFEQILSLPELKANPFKERICMVFSTSPTRDSLSFEDFLDLLSVFSDTA
                     TPDIKSHYAFRIFDFDDDGTLDREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES
                     DIDRDGTINLSEFQHVISRSPDFASSFKIVL"
     exon            98..132
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     exon            133..241
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     exon            242..392
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     exon            393..511
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     exon            512..600
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
     exon            601..836
                     /gene="Cib1"
                     /gene_synonym="Cib; Sip2-28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcgtccc ggggagagtt ggccgagctg tgcgcgcacc gcggcgatgg gaggttcggg
       61 cagtcgcctg tctaaggagc tgctggccga gtaccaggac ctgacgttcc tgaccaagca
      121 ggagatcctc cttgcccaca gacgcttttg cgagttgctt cccccagagc atcggaccgt
      181 ggaagagtca ctgcataccc gagtatcttt tgagcagatc ctcagccttc cagagctcaa
      241 ggccaacccc ttcaaggagc gaatctgcat ggtcttctcc acgtcgccta ccagagacag
      301 cctgagcttt gaggacttcc tggacctcct gagtgtcttc agtgacacag caaccccaga
      361 catcaagtca cactatgcct tccgcatctt tgactttgat gatgatggaa ccctggacag
      421 agaagacctg agccggcttg tgaactgcct cacgggagag ggcgaggaca ctcggctcag
      481 tgcttctgag atgaagcagc tcatcgacaa tatcctggaa gagtcggaca ttgacaggga
      541 tgggaccatc aatctctccg agttccagca cgtcatctct cgctcaccag actttgccag
      601 ctcctttaag attgtcctgt gatggctttc aagtaccaac atcctgtcca agacctttcc
      661 actgctgaga tgtggccaag gttatgcctg cggtgtcagg gccagagccg gcccagcctg
      721 gagagggcgc tgcagagtct ggccccctgg caggggagga ctctccccct tgtcactgct
      781 gttgccatca ctgtttttac taattggtaa taaaggttta gaaatgtttg acttcc
//
