LOCUS       NM_001008327            1165 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus cytosolic iron-sulfur assembly component 2A
            (Ciao2a), mRNA.
ACCESSION   NM_001008327 XM_217178
VERSION     NM_001008327.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Paul VD and Lill R.
  TITLE     Biogenesis of cytosolic and nuclear iron-sulfur proteins and their
            role in genome stability
  JOURNAL   Biochim Biophys Acta 1853 (6), 1528-1539 (2015)
   PUBMED   25583461
  REMARK    Review article
REFERENCE   2  (bases 1 to 1165)
  AUTHORS   Maio N and Rouault TA.
  TITLE     Iron-sulfur cluster biogenesis in mammalian cells: New insights
            into the molecular mechanisms of cluster delivery
  JOURNAL   Biochim Biophys Acta 1853 (6), 1493-1512 (2015)
   PUBMED   25245479
  REMARK    Review article
REFERENCE   3  (bases 1 to 1165)
  AUTHORS   Stehling O, Mascarenhas J, Vashisht AA, Sheftel AD, Niggemeyer B,
            Rosser R, Pierik AJ, Wohlschlegel JA and Lill R.
  TITLE     Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and
            maturation of different subsets of cytosolic-nuclear iron-sulfur
            proteins
  JOURNAL   Cell Metab 18 (2), 187-198 (2013)
   PUBMED   23891004
  REMARK    Erratum:[Cell Metab. 2018 Jan 9;27(1):263. PMID: 29320706]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086524.1.
            
            On Dec 16, 2004 this sequence version replaced XM_217178.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086524.1, FQ218618.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1165
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /note="cytosolic iron-sulfur assembly component 2A"
                     /db_xref="GeneID:300797"
                     /db_xref="RGD:1307481"
     exon            1..257
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..616
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /note="MIP18 family protein FAM96A; family with sequence
                     similarity 96, member A"
                     /codon_start=1
                     /product="cytosolic iron-sulfur assembly component 2A
                     precursor"
                     /protein_id="NP_001008328.1"
                     /db_xref="GeneID:300797"
                     /db_xref="RGD:1307481"
                     /translation="MERVSGLLSWTLSRVLWLSGFSEQGAAWQPRIMEEKALEVYDLI
                     RTIRDPEKPNTLEELEVVTESCVEVQEISEDDYLVIIKFTPTVPHCSLATLIGLCLRV
                     KLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCVLEPD
                     "
     exon            258..422
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /inference="alignment:Splign:2.1.0"
     exon            423..472
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /inference="alignment:Splign:2.1.0"
     exon            473..518
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /inference="alignment:Splign:2.1.0"
     exon            519..1142
                     /gene="Ciao2a"
                     /gene_synonym="Fam96a; RGD1307481"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctattctc tgctccccta aacctttaca catgtcttgg tttatttgaa gtccaggaag
       61 ttaacttctg agatcggctg cggaaagacg gtggctcggt tgggacagtc gccagggatg
      121 gcggaacgtc aggatggagc gagtgtctgg gctgctctcc tggacgctga gcagggtcct
      181 atggctctca ggcttttctg agcagggagc tgcctggcag ccccggatca tggaagagaa
      241 agcgctagaa gtttatgatt tgattcgaac tatccgggac ccagaaaagc ccaatacttt
      301 agaagaactg gaagtggtca cagagagttg tgtggaagtt caagaaataa gtgaagatga
      361 ctatttggtt attatcaagt tcacaccaac agtacctcat tgctctttgg caactcttat
      421 tggactgtgc ttaagagtaa agctccagcg atgtctgcca ttcaaacaca agctggaaat
      481 ttacatttct gaaggaactc actcgacaga agaagacatc aacaagcaga taaatgacaa
      541 agagcgagtg gcagctgcaa tggagaaccc caaccttcgg gagattgtgg aacagtgcgt
      601 cctcgagccg gactgacgcc ttcctaagag ccagtggcct ggaagcattt gatctgcttg
      661 tttaaatcct ttgaaaaatg tagaggacac atgtcgacta tataggtgat ttgtacctca
      721 gacctttttt tttgtttttt gttttttcaa gacaaggttt ttctgtatag tcctggctgt
      781 cctggaactt gttctgttga ccagactggc cttgaactca gagatccacc tggctctgtc
      841 ttctgaaagc tgggattaaa ggtgtgagcc accactggcc agccttcaga gtgttttttt
      901 aaaaggcttc tttctgagca gatttcagtt atgaggtaaa ttctaattgt tcagtgagta
      961 acattctcag gatttctaac tcaagtgatc atacagaaaa atattttcta gttattatgt
     1021 gtaaaatgtt actatttttc tgatgaccat tctgatacaa ctgtttttca tgtcaaatat
     1081 ctactgtgcc caaatgtatt tgatttaaat cattctaaaa taaatatgac agatgattct
     1141 taaaaaaaaa aaaaaaaaaa aaaaa
//
