LOCUS       NM_001105773            3100 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chromosome transmission fidelity factor 18
            (Chtf18), mRNA.
ACCESSION   NM_001105773 XM_001060640 XM_213250
VERSION     NM_001105773.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Berkowitz,K.M., Sowash,A.R., Koenig,L.R., Urcuyo,D., Khan,F.,
            Yang,F., Wang,P.J., Jongens,T.A. and Kaestner,K.H.
  TITLE     Disruption of CHTF18 causes defective meiotic recombination in male
            mice
  JOURNAL   PLoS Genet 8 (11), e1002996 (2012)
   PUBMED   23133398
REFERENCE   2  (bases 1 to 3100)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 3100)
  AUTHORS   Berkowitz,K.M., Kaestner,K.H. and Jongens,T.A.
  TITLE     Germline expression of mammalian CTF18, an evolutionarily conserved
            protein required for germ cell proliferation in the fly and sister
            chromatid cohesion in yeast
  JOURNAL   Mol Hum Reprod 14 (3), 143-150 (2008)
   PUBMED   18250106
REFERENCE   4  (bases 1 to 3100)
  AUTHORS   Bermudez,V.P., Maniwa,Y., Tappin,I., Ozato,K., Yokomori,K. and
            Hurwitz,J.
  TITLE     The alternative Ctf18-Dcc1-Ctf8-replication factor C complex
            required for sister chromatid cohesion loads proliferating cell
            nuclear antigen onto DNA
  JOURNAL   Proc Natl Acad Sci U S A 100 (18), 10237-10242 (2003)
   PUBMED   12930902
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213250.4, XM_001060640.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..3100
                     /gene="Chtf18"
                     /note="chromosome transmission fidelity factor 18"
                     /db_xref="GeneID:287146"
                     /db_xref="RGD:1310473"
     exon            1..166
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..2982
                     /gene="Chtf18"
                     /note="CTF18, chromosome transmission fidelity factor 18
                     homolog"
                     /codon_start=1
                     /product="chromosome transmission fidelity protein 18
                     homolog"
                     /protein_id="NP_001099243.1"
                     /db_xref="GeneID:287146"
                     /db_xref="RGD:1310473"
                     /translation="MEDYEEDLYGVEDDFQNQFAAELEVLAELEGTGDLAPSETLQTP
                     ASRPPLTFEEAIAGGDIVPRPCPAGSSGNDSRNTRKNVRRDQPAPSSPMVKRPRLDVV
                     KRLNFEPDKEELLYPDSPPGDITPPPSPEVFPEMWDAGPSDAGADNGLMQALPSPRNP
                     VLRRPPVLEDYINVTSTCGERAFLVLRADLTGTGVQNHLPDVQWRGRGQLDLLGVPFT
                     SLKEQVDNKRRQQLLEEAQQLSDTLHSLRSEGEEAMLEGPPEEEPGPGQETAQHCLWV
                     DEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPARKPRPGVEPTRVGKEAPAP
                     GKWKSHEQVLEEMLEAELDPSRRPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMN
                     ASDDRSPEAFRTRIEAATQMESVLGAGGRPNCLVIDEIDGAPTAAINVLLSILNRKGP
                     QEAEQGGTAVAAAGGRRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLP
                     SRLVQRLQEISLQHGMRSDPGALAALCEKTDNDIRACINTLQFLYGRGQRELSVKDVQ
                     TTHVGLKDQRKGLFSVWQEVFQLPRAQRRLVGQDLMLPTHALLLNDSDKGSLTLASQR
                     FYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLGTVCCALDWLAFDDLLEQAAHHG
                     QSFQLLRYLPFLPAAFHVLFASSHVPRITFPSSQQEAQTRLSQTRNHIQTLVSGMAPA
                     TRSRATPQALVLDTLCLLLDVLSPKLRPVSTQLYSAREKQQLSSLVGTMLAYSLTYHQ
                     ERTPDGQYLYRLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMWRAEALAWTG
                     GGPQVDQGPSGPANLRTDSGEKGTRQPAPRNHEQRLEHIMKRAAVQEQPERDFFGRVV
                     IRKVAVPSKEVEAPQKDTDEWRMGVAVGRSEVWFRFNEGVSNAVRRSLYIRDLL"
     exon            167..346
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            347..494
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            495..663
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            664..756
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            757..809
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            810..948
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1158
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1256
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1380
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1532
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1626
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1725
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1856
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..2004
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2005..2229
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2230..2379
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..2510
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2655
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2656..2787
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2788..2845
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
     exon            2846..3100
                     /gene="Chtf18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgatggc agtggcgcgg gaagttctga gggaagctta gctgtagaag ctgtggtctg
       61 cctgcaccgg ggaccatgga agactacgag gaagatctgt atggtgtgga ggatgacttc
      121 caaaatcagt tcgcggccga actcgaagtg ctggcggagc tggaaggaac aggggacctg
      181 gcgccttctg agaccctcca gactccggcg agccgccccc cgctgacctt cgaagaggcc
      241 atcgctggtg gggacattgt cccacgtcct tgccctgcag ggtcctcagg aaatgacagc
      301 cgcaatacca gaaagaatgt tcgtagggac cagcccgcgc cctccagccc catggtcaaa
      361 cggcccaggt tggacgtggt gaagaggctg aacttcgagc cagataaaga ggagctcttg
      421 taccccgatt ctcctcctgg ggacatcacc cccccaccga gtccagaggt cttccctgag
      481 atgtgggatg ctgggccctc agatgctggt gctgacaatg gcctcatgca ggcattgcca
      541 agtccccgca atcccgttct gagacggccc cctgtcttag aggattacat caatgtgacg
      601 tccacgtgtg gagagcgggc ctttttggtg cttcgggctg acctcacagg cactggggtg
      661 cagaaccatc ttcctgatgt ccagtggcga ggccgtggcc agctggacct tctgggtgtc
      721 cccttcacct ccctgaagga gcaagttgac aacaagagac ggcagcaact gcttgaggag
      781 gcccaacagc tttcagacac tctacatagc ctcaggtctg aaggggaaga ggccatgctt
      841 gaggggcccc ctgaggagga gccgggccct ggccaggaga ctgctcagca ctgcctctgg
      901 gtggacgagt ttgcacccca gcactacaca gaactgctca gtgatgactt taccaaccgc
      961 tgccttctca aatggctgaa gctatgggac cttgtggtgt ttggtcatga gaggcctgcc
     1021 cggaagccca gacctggtgt agagcccacc cgggttggga aggaggcccc agcccctggc
     1081 aagtggaaga gtcatgagca ggtactggag gaaatgctag aagctgagct ggacccgagc
     1141 cggaggcctc ggcagaaggt ggcactgctg tgtggccctc caggattagg caagaccacg
     1201 ctggctcatg tggtcgcaag gcatgctggg tattgcgtgg tagagatgaa tgcaagtgat
     1261 gaccgtagcc ccgaggcctt ccgtacacgc attgaagcag ctacacaaat ggagtcggtg
     1321 ctaggtgccg gtgggaggcc caactgcttg gttatcgatg agattgatgg agcccccacg
     1381 gcggcgatca acgttctctt gagcatcttg aatcgcaagg gcccgcagga ggctgagcaa
     1441 gggggcacag ctgtggctgc ggcaggggga cggcgacgca gggctgaggg gggcctcctg
     1501 accaggccta tcatctgcat ctgcaatgat cagttcacac cttctttgag gcagctgaag
     1561 cagcaggctc ttctgctcca cgtcccacca actctgccct ccaggctggt gcagcggctc
     1621 caggagatct ccctgcagca cggcatgcgg tctgacccgg gtgcactggc tgccctctgt
     1681 gagaagacag acaatgacat ccgtgcctgc atcaacacac tacagtttct gtatgggagg
     1741 ggccagcggg agctgagcgt gaaggatgtg cagaccaccc atgtcggcct gaaagaccag
     1801 cgcaaggggc tattctctgt gtggcaagag gtcttccagt tgcccagggc tcaaaggcga
     1861 cttgtgggcc aggacctgat gctaccaacc catgctctcc tgctcaatga cagtgacaag
     1921 ggctctctga ccttggcttc ccagcgcttc taccacatcc tgcgtgtgac cacttctgca
     1981 ggcgagcatg agaaggttgt gcagggcctg tttgacaact ttctacgcct gcggcttcgg
     2041 gactccagcc tgggcaccgt gtgctgtgcc cttgactggc tggccttcga tgacctgctg
     2101 gaacaggcgg cccaccacgg ccagagcttt cagctgctgc gttacttgcc cttcctgccc
     2161 gcggccttcc acgtgctctt cgcctccagc cacgtgccgc gcatcacttt ccccagcagc
     2221 cagcaggagg cccagacccg gttgagccag acaaggaacc acatacagac tctggtgtca
     2281 ggaatggcac cagccactcg cagccgggcc accccgcagg ctcttgttct agatactctc
     2341 tgcctgctcc tggatgtcct ctcgcctaag ctgcgccccg tgagcacaca gctgtacagt
     2401 gcccgtgaga agcagcagtt gtcgagcctt gtgggcacca tgcttgccta tagcctcacc
     2461 taccaccagg agcgcacacc tgatgggcag tacctctaca ggctggagcc gaatgtggag
     2521 gaggtctgcc gcttcccaga actacctgcc cgcaagcccc tcacctacca ggctaagcag
     2581 cttattgccc gggagattga aatggagaag atgtggaggg cagaggcttt ggcctggact
     2641 ggaggtggcc ctcaggtgga ccagggtccc tcagggcctg caaatctgcg gacggacagt
     2701 ggggaaaagg ggacgaggca gcctgccccc cgtaaccatg agcagcggct agaacacatc
     2761 atgaagagag cagccgtgca ggagcagcct gagagggact tctttggacg tgtggtcatc
     2821 aggaaagtgg cagtcccaag caaagaggtt gaggcccccc agaaggacac ggacgagtgg
     2881 cgcatgggtg tggcagtggg caggagtgag gtgtggttcc ggttcaacga gggtgtctcc
     2941 aatgctgttc ggcgcagcct gtacatcagg gacctgctgt agccccactg ccccaggaca
     3001 tcagatcaga ctgactccca cagggatgta ccagggcaga gactcctgga gaagtctgtt
     3061 tataaagtca caccttaaca gagagtgcgg gtcaggctca
//
